Design of antibody variable fragments with reduced reactivity to preexisting anti-drug antibodies
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - June 14, 2023 Category: Biomedical Science Authors: Maria U. Johansson Christopher Weinert Dietrich Alexander Reichardt Dana Mahler Dania Diem Christian Hess Diana Feusi Simon Carnal Julia Tietz Noreen Giezendanner Fabio Mario Spiga David Urech Stefan Warmuth Source Type: research

Characterization of anti-SARS-CoV-2 monoclonal antibodies focusing on antigen binding, neutralization, and Fc γR activation via formation of immune complex
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - June 13, 2023 Category: Biomedical Science Authors: Minoru TadaMichihiko AoyamaAkiko Ishii-WatabeDivision of Biological Chemistry and Biologicals, National Institute of Health Sciences, Kawasaki, Japan Source Type: research

Affinity-controlled capture and release of engineered monoclonal antibodies by macroporous dextran hydrogels using coiled-coil interactions
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - June 10, 2023 Category: Biomedical Science Authors: Seyed Farzad BaniahmadRomane OliverioInes Obregon-GomezAlma RobertAnne E.G. LenferinkElena PazosNick VirgilioXavier BanquyGregory De CrescenzoYves Durochera Department of Biochemistry and Molecular Medicine, Faculty of Medicine, University of Montreal, Mo Source Type: research

Generation of a novel fully human non-superagonistic anti-CD28 antibody with efficient and safe T-cell co-stimulation properties
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - June 8, 2023 Category: Biomedical Science Authors: Abdullah ElsayedChristian PellegrinoLouis Pl üssFrederik PeissertRamon BenzFranziska UlrichGudrun ThorhallsdottirSheila Dakhel PlazaAlessandra VillaJacqueline MockEmanuele PucaRoberto De LucaMarkus G. ManzCornelia HalinDario Neria Philochem AG, Libernstr Source Type: research

In-line product quality monitoring during biopharmaceutical manufacturing using computational Raman spectroscopy
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - June 8, 2023 Category: Biomedical Science Authors: Jiarui WangJingyi ChenJoey StudtsGang Wanga Boehringer Ingelheim Pharma GmbH/Co. KG, Biberach an der Riss, Germanyb Karlsruhe Institute of Technology, Karlsruhe, Germany Source Type: research

Generation of a novel fully human non-superagonistic anti-CD28 antibody with efficient and safe T-cell co-stimulation properties
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - June 8, 2023 Category: Biomedical Science Authors: Abdullah Elsayed Christian Pellegrino Louis Pl üss Frederik Peissert Ramon Benz Franziska Ulrich Gudrun Thorhallsdottir Sheila Dakhel Plaza Alessandra Villa Jacqueline Mock Emanuele Puca Roberto De Luca Markus G. Manz Cornelia Halin Dario Neri Source Type: research

In-line product quality monitoring during biopharmaceutical manufacturing using computational Raman spectroscopy
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - June 8, 2023 Category: Biomedical Science Authors: Jiarui Wang Jingyi Chen Joey Studts Gang Wang Source Type: research

Effects of the COVID-19 pandemic: new approaches for accelerated delivery of gene to first-in-human CMC data for recombinant proteins
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - June 6, 2023 Category: Biomedical Science Authors: Herv é BrolyJonathan SouquetAlain Becka Biotech Process Sciences, Merck-Serono, Corsier-Sur-Vevey, Switzerlandb Biologics CMC and Developability, IRPF, Centre d’Immunologie Pierre Fabre, Saint-Julien-En-Genevois, France Source Type: research

A systematic review of commercial high concentration antibody drug products approved in the US: formulation composition, dosage form design and primary packaging considerations
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - May 27, 2023 Category: Biomedical Science Authors: Indrajit GhoshHiten GutkaMary E. KrauseRyan ClemensRamesh S. Kashia Sterile Product Development, Bristol Myers Squibb, New Brunswick, NJ, USAb College of Pharmacy, University of Illinois at Chicago, Chicago, USAc Sterile Product Development, Bristol Myers Source Type: research

Generation and in vivo characterization of a novel high-affinity human antibody targeting carcinoembryonic antigen
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - May 27, 2023 Category: Biomedical Science Authors: Louis Pl üssFrederik PeissertAbdullah ElsayedGiulia RottaJonas RömerSheila Dakhel PlazaAlessandra VillaEmanuele PucaRoberto De LucaAnnette OxeniusDario Neria Philochem AG, Libernstrasse 3, Otelfingen, Switzerlandb Department of Biology, Swiss Federal In Source Type: research

Molecular recognition requires dimerization of a VHH antibody
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - May 27, 2023 Category: Biomedical Science Authors: Christopher A. SmithGregory J. SonnesonRobert J. HoeyJennifer M. HinermanKimberly SheehyRichard WalterAndrew B. HerrJames R. Horna Department of Chemistry and Biochemistry, Northern Illinois University, DeKalb, IL, USAb Division of Immunobiology, Cincinna Source Type: research

Generation and in vivo characterization of a novel high-affinity human antibody targeting carcinoembryonic antigen
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - May 27, 2023 Category: Biomedical Science Authors: Louis Pl üss Frederik Peissert Abdullah Elsayed Giulia Rotta Jonas R ömer Sheila Dakhel Plaza Alessandra Villa Emanuele Puca Roberto De Luca Annette Oxenius Dario Neri Source Type: research