Development and pharmacokinetic assessment of a fully canine anti-PD-1 monoclonal antibody for comparative translational research in dogs with spontaneous tumors
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - December 4, 2023 Category: Biomedical Science Authors: Sho YoshimotoNicholas ChesterAilian XiongEnrico RadaelliHong WangMarc BrillantesGayathri GulendranPatrick GlassmanDon L. SiegelNicola J. Masona Department of Clinical Sciences and Advanced Medicine, School of Veterinary Medicine, University of Pennsylvani Source Type: research
Anti-citrullinated histone monoclonal antibody CIT-013, a dual action therapeutic for neutrophil extracellular trap-associated autoimmune diseases
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - November 30, 2023 Category: Biomedical Science Authors: Maarten van der LindenSangeeta KumariDaphne MontizaanStephanie van DalenAnnemarie KipMartyn FosterInge Reinieren-BeerenElsa NeubertLuise ErpenbeckKelsy WaaijenbergTirza BruurmijnRezie te PoelePeter van ZandvoortPaul VinkEric MeldrumHelmuth van EsRenato G. Source Type: research
Monoclonal antibody and protein therapeutic formulations for subcutaneous delivery: high-concentration, low-volume vs. low-concentration, high-volume
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - November 28, 2023 Category: Biomedical Science Authors: M. DesaiA. KunduM. HagemanH. LouD. Boisverta Medical Affairs, Enable Injections, Inc, Cincinnati, OH, USAb Manufacturing Sciences, Takeda Pharmaceuticals, Brooklyn Park, MN, USAc Department of Pharmaceutical Chemistry, The University of Kansas, Lawrence, Source Type: research
BERT2DAb: a pre-trained model for antibody representation based on amino acid sequences and 2D-structure
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - November 27, 2023 Category: Biomedical Science Authors: Xiaowei LuoFan TongWenbin ZhaoXiangwen ZhengJiangyu LiJing LiDongsheng Zhaoa Information Center, Academy of Military Medical Sciences, Beijing, Chinab State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Be Source Type: research
Epitope mapping of monoclonal antibodies: a comprehensive comparison of different technologies
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - November 27, 2023 Category: Biomedical Science Authors: Xibei DangLars GuelenDavid Lutje HulsikGrigori ErmakovEdward J. HsiehJoost KreijtzJudith Stammen-VogelzangsImke LodewijksAstrid BertensArne BramerMarco GuadagnoliAlexis NazabalAndrea van ElsasThierry FischmannVeronica JuanAmy BeebeMaribel BeaumontHans van Source Type: research
Correction
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - November 27, 2023 Category: Biomedical Science Source Type: research
Robust production of monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the CH1-C λ interface
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - November 6, 2023 Category: Biomedical Science Authors: John D. BagertVaheh OganesyanChi-I ChiangMike IannottiJia LinChunning YangSterling PayneWill McMahonSamuel EdwardsAndrew DippelMark HutchinsonFengying HuangVineela AletiChendi NiuChen QianJessica DenhamSofia FerreiraPallab PradhanMark PenneyChunlei WangWe Source Type: research
A window into the human immune system: comprehensive characterization of the complexity of antibody complementary-determining regions in functional antibodies
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - October 25, 2023 Category: Biomedical Science Authors: Oscar Mejias-GomezAndreas V. MadsenKerstin SkovgaardLasse E. PedersenJ. Preben MorthTimothy P. JenkinsPeter KristensenSteffen Goletza Department of Biotechnology and Biomedicine, Technical University of Denmark, Kgs. Lyngby, Denmarkb Department of Chemist Source Type: research
Utility of physiologically based pharmacokinetic modeling to predict inter-antibody variability in monoclonal antibody pharmacokinetics in mice
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - October 12, 2023 Category: Biomedical Science Authors: Shufang LiuSara C. HumphreysKevin D. CookKip P. ConnerAna R. CorreiaAlex W. JacobitzMelissa YangRonya PrimackMarcus SotoRupa PadakiMariusz LubomirskiRichard SmithMarissa MockVeena A. Thomasa Department of Pharmacokinetics and Drug Metabolism, Amgen Inc, S Source Type: research
Delivery of the Brainshuttle ™ amyloid-beta antibody fusion trontinemab to non-human primate brain and projected efficacious dose regimens in humans
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - October 12, 2023 Category: Biomedical Science Authors: Hans Peter GrimmVanessa SchumacherMartin Sch äferSabine Imhof-JungPer-Ola FreskgårdKevin BradyCarsten HofmannPetra RügerTilman SchlothauerUlrich GöpfertMaximilian HartlSylvia RottachAdrian ZwickShanon SegerRachel NeffJens NiewoehnerNiels Janssena Roch Source Type: research
Utility of physiologically based pharmacokinetic modeling to predict inter-antibody variability in monoclonal antibody pharmacokinetics in mice
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - October 12, 2023 Category: Biomedical Science Authors: Shufang LiuSara C. HumphreysKevin D. CookKip P. ConnerAna R. CorreiaAlex W. JacobitzMelissa YangRonya PrimackMarcus SotoRupa PadakiMariusz LubomirskiRichard SmithMarissa MockVeena A. Thomasa Department of Pharmacokinetics and Drug Metabolism, Amgen Inc, S Source Type: research
Delivery of the Brainshuttle ™ amyloid-beta antibody fusion trontinemab to non-human primate brain and projected efficacious dose regimens in humans
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - October 12, 2023 Category: Biomedical Science Authors: Hans Peter GrimmVanessa SchumacherMartin Sch äferSabine Imhof-JungPer-Ola FreskgårdKevin BradyCarsten HofmannPetra RügerTilman SchlothauerUlrich GöpfertMaximilian HartlSylvia RottachAdrian ZwickShanon SegerRachel NeffJens NiewoehnerNiels Janssena Roch Source Type: research
A library approach for the de novo high-throughput isolation of humanized VHH domains with favorable developability properties following camelid immunization
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - September 28, 2023 Category: Biomedical Science Authors: Paul ArrasHan Byul YooLukas PekarChristian Schr öterThomas ClarkeSimon KrahDaniel KlewinghausVanessa SiegmundAndreas EversStefan Zielonkaa Antibody Discovery & Protein Engineering, Merck Healthcare KGaA, Darmstadt, Germanyb Institute for Organic Chemist Source Type: research
Identification of tyrosine sulfation in the variable region of a bispecific antibody and its effect on stability and biological activity
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - September 24, 2023 Category: Biomedical Science Authors: Christopher B. LietzEkaterina DeyanovaYounhee ChoJon CordiaSarah FrancSally KabroSteven WangDavid MikolonDouglas D. Banksa Department of Pharmaceutical Candidate Optimization - DMPK, Bristol Myers Squibb, San Diego, CA, USAb Department of Pharmaceutical C Source Type: research
