Molecular recognition requires dimerization of a VHH antibody
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - May 27, 2023 Category: Biomedical Science Authors: Christopher A. Smith Gregory J. Sonneson Robert J. Hoey Jennifer M. Hinerman Kimberly Sheehy Richard Walter Andrew B. Herr James R. Horn Source Type: research

A systematic review of commercial high concentration antibody drug products approved in the US: formulation composition, dosage form design and primary packaging considerations
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - May 27, 2023 Category: Biomedical Science Authors: Indrajit Ghosh Hiten Gutka Mary E. Krause Ryan Clemens Ramesh S. Kashi Source Type: research

Multivalent IgM scaffold enhances the therapeutic potential of variant-agnostic ACE2 decoys against SARS-CoV-2
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - May 25, 2023 Category: Biomedical Science Authors: Meghan M. VerstraeteFlorian HeinkelJanessa LiSiran CaoAnh TranElizabeth C. HalversonRobert GeneElizabeth StangleBegonia Silva-MorenoSifa ArrafiJegarubee BavananthasivamMadeline FungMariam Eji-LasisiStephanie MastermanSteve XanthoudakisSurjit DixitJohn Bab Source Type: research

Identification and characterization of an unexpected isomerization motif in CDRH2 that affects antibody activity
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - May 25, 2023 Category: Biomedical Science Authors: Meiqi YiJian SunHanzi SunYifei WangShan HouBeibei JiangYuanyuan XieRuyue JiLiu XueXiao DingXiaomin SongApril XuChichi HuangQuan QuanJing Songa Department of Biologics, BeiGene (Beijing) Co. Ltd, Beijing, Chinab Department of Molecular Science, BeiGene (Be Source Type: research

Multivalent IgM scaffold enhances the therapeutic potential of variant-agnostic ACE2 decoys against SARS-CoV-2
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - May 25, 2023 Category: Biomedical Science Authors: Meghan M. Verstraete Florian Heinkel Janessa Li Siran Cao Anh Tran Elizabeth C. Halverson Robert Gene Elizabeth Stangle Begonia Silva-Moreno Sifa Arrafi Jegarubee Bavananthasivam Madeline Fung Mariam Eji-Lasisi Stephanie Masterman Steve Xanthoudakis Surji Source Type: research

Evolution of phage display libraries for therapeutic antibody discovery
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - May 24, 2023 Category: Biomedical Science Authors: Yang ZhangConsultant for Biopharma Companies, New York, USA Source Type: research

Ranking mAb –excipient interactions in biologics formulations by NMR spectroscopy and computational approaches
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - May 23, 2023 Category: Biomedical Science Authors: Chunting ZhangSteven T. GossertJonathan WilliamsMichael LittleMarilia BarrosBarton DearBradley FalkAnkit D. KantheRobert GarmiseLuciano MuellerAndrew IlottAnuji Abrahama Drug Product Development, Bristol Myers Squibb, New Brunswick, NJ, USAb Drug Discover Source Type: research

Technical advancement and practical considerations of LC-MS/MS-based methods for host cell protein identification and quantitation to support process development
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - May 23, 2023 Category: Biomedical Science Authors: Jia GuoRegina KuferDelia LiStefanie WohlrabMidori Greenwood-GoodwinFeng Yanga Protein Analytical Chemistry, Genentech, A Member of the Roche Group, South San Francisco, CA, USAb Pharma Technical Development Analytics, Roche Diagnostics GmbH, Penzberg, Ger Source Type: research

Ranking mAb –excipient interactions in biologics formulations by NMR spectroscopy and computational approaches
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - May 23, 2023 Category: Biomedical Science Authors: Chunting Zhang Steven T. Gossert Jonathan Williams Michael Little Marilia Barros Barton Dear Bradley Falk Ankit D. Kanthe Robert Garmise Luciano Mueller Andrew Ilott Anuji Abraham Source Type: research

GlycoVHH: optimal sites for introducing N-glycans on the camelid VHH antibody scaffold and use for macrophage delivery
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - May 22, 2023 Category: Biomedical Science Authors: Loes van SchieWander Van BreedamCharlotte RoelsBert SchepensMartin FrankAhmad Reza MehdipourBram LaukensWim NerinckxFrancis SantensSimon DevosIebe RosseyKarel ThooftSandrine VanmarckeAnnelies Van HeckeXavier SaelensNico Callewaerta UGent Department of Bio Source Type: research

IL-38 blockade induces anti-tumor immunity by abrogating tumor-mediated suppression of early immune activation
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - May 22, 2023 Category: Biomedical Science Authors: John P. DowlingPavel A. NikitinFang ShenHalley ShuklaJames P. FinnNirja PatelCezary SwiderJamie L. Bingaman-SteeleChris NicolescuEden L SikorskiEvan J. GreenawaltMichael J. MorinMatthew K. RobinsonKaren LundgrenBenjamin C. HarmanResearch & Development, I Source Type: research