Antibodies to watch in 2023
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - December 6, 2022 Category: Biomedical Science Authors: H élène KaplonSilvia CrescioliAlicia ChenowethJyothsna VisweswaraiahJanice M. Reicherta Translational Medicine Department, Institut de Recherches Internationales Servier Suresnes, Franceb St. John’s Institute of Dermatology, School of Basic & Medical Source Type: research

A novel anti-NGF PEGylated Fab ’ provides analgesia with lower risk of adverse effects
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - December 2, 2022 Category: Biomedical Science Authors: Yukari KoyaHirotsugu TanakaEiji YoshimiNobuaki TakeshitaShuji MoritaHiroki MorioKanako MoriHiroshi FushikiMasazumi Kamoharaa Drug Discovery Research, Astellas Pharma Inc, Tsukuba, Japanb Incubation Lab, Astellas Innovation Management LLC, Cambridge, MA, U Source Type: research

Kinetic analysis of ternary and binary binding modes of the bispecific antibody emicizumab
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - December 1, 2022 Category: Biomedical Science Authors: Stefanie MakAgnes MarszalNena MatschekoUlrich RantDynamic Biosensors GmbH, Munich, Germany Source Type: research

A glyco-engineering approach for site-specific conjugation to Fab glycans
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - November 30, 2022 Category: Biomedical Science Authors: Maria L. JaramilloTraian SuleaYves DurocherMauro AcchioneMelissa J. SchurAnna RobothamJohn F. KellyMarie-France GoneauAlma RobertYuneivy Cepero-DonatesMichel Gilberta Human Health Therapeutics Research Centre, National Research Council Canada, 6100 Royalm Source Type: research

Reduction of therapeutic antibody self-association using yeast-display selections and machine learning
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - November 26, 2022 Category: Biomedical Science Authors: Emily K. Makowski Hongwei Chen Matthew Lambert Eric M. Bennett Nicole S. Eschmann Yulei Zhang Jennifer M. Zupancic Alec A. Desai Matthew D. Smith Wenjia Lou Amendra Fernando Timothy Tully Christopher J. Gallo Laura Lin Peter M. Tessier Source Type: research

Non-human primates in the PKPD evaluation of biologics: Needs and options to reduce, refine, and replace. A BioSafe White Paper
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - November 24, 2022 Category: Biomedical Science Authors: Karelle M énochet Hongbin Yu Bonnie Wang Jay Tibbitts Cheng-Pang Hsu Amrita V. Kamath Wolfgang F. Richter Andreas Baumann Source Type: research

A computational method for predicting the aggregation propensity of IgG1 and IgG4(P) mAbs in common storage buffers
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - November 24, 2022 Category: Biomedical Science Authors: James T. Heads Sebastian Kelm Kerry Tyson Alastair D. G. Lawson Source Type: research

Enhanced immunogenic potential of cancer immunotherapy antibodies in human IgG1 transgenic mice
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - November 17, 2022 Category: Biomedical Science Authors: Jerome Egli Stefan Heiler Felix Weber Guido Steiner Timo Schwandt Katharine Bray-French Christian Klein Sebastian Fenn Gregor P. Lotz Eugenia Opolka-Hoffmann Thomas E. Kraft Laetitia Petersen Rebecca Moser Jonathan DeGeer Michel Siegel Daniela Finke Julia Source Type: research

Clearance of therapeutic antibody glycoforms after subcutaneous and intravenous injection in a porcine model
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - November 16, 2022 Category: Biomedical Science Authors: David Falck Martin Lechmann Ana Mom čilović Marco Thomann Carolien A. M. Koeleman Cordula Jany Sebastian Malik Manfred Wuhrer Dietmar Reusch Source Type: research

Deciphering deamidation and isomerization in therapeutic proteins: Effect of neighboring residue
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - November 15, 2022 Category: Biomedical Science Authors: Flaviyan Jerome Irudayanathan Jonathan Zarzar Jasper Lin Saeed Izadi Source Type: research

Engineering a pure and stable heterodimeric IgA for the development of multispecific therapeutics
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - November 7, 2022 Category: Biomedical Science Authors: Florian Heinkel Meghan M. Verstraete Siran Cao Janessa Li Patrick Farber Elizabeth Stangle Begonia Silva-Moreno Fangni Peng Surjit Dixit Martin J. Boulanger Thomas Spreter Von Kreudenstein Eric Escobar-Cabrera Source Type: research