Bivalent non-human gal- α1-3-gal glycan epitopes in the Fc region of a monoclonal antibody model can be recognized by anti-Gal-α1-3-Gal IgE antibodies
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - July 27, 2023 Category: Biomedical Science Authors: Grayson HatfieldLioudmila TepliakovaJessica TranHuixin LuMichel GilbertRoger Y. Tama Centre for Oncology, Radiopharmaceuticals and Research, Biologic and Radiopharmaceutical Drugs Directorate, Health Canada, Ottawa, Ontario, Canadab Human Health Therapeut Source Type: research
Generation and engineering of potent single domain antibody-based bispecific IL-18 mimetics resistant to IL-18BP decoy receptor inhibition
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - July 20, 2023 Category: Biomedical Science Authors: Britta LipinskiLaura UnmuthPaul ArrasStefan BeckerChristina BauerLars ToleikisSimon KrahAchim DoernerDesislava YanakievaAmmelie Svea BojeKatja KlauszMatthias PeippVanessa SiegmundAndreas EversHarald KolmarLukas PekarStefan Zielonkaa Antibody Discovery and Source Type: research
Prediction of long-term polysorbate degradation according to short-term degradation kinetics
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - July 7, 2023 Category: Biomedical Science Authors: Sisi ZhangCaterina RiccardiDane CarlsonDouglas KamenKenneth S. GrahamMohammed ShameemHanne BakHui XiaoNing Lia Analytical Chemistry, Regeneron Pharmaceuticals, Tarrytown, NY, USAb Formulation Group, Regeneron Pharmaceuticals, Tarrytown, NY, USAc Preclinic Source Type: research
Improved antibody pharmacokinetics by disruption of contiguous positive surface potential and charge reduction using alternate human framework
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - July 6, 2023 Category: Biomedical Science Authors: Romain OllierAline FuchsFlorence GauyeKatarzyna PiorkowskaS ébastien MenantMonisha RatnamPaolo MontanariFlorence GuilhotDidier PhillipeMickael AudrainAnne-Laure EgesipeDamien NévoltrisTamara SeredeninaAndrea PfeiferMarie Kosco-VilboisTariq AfrozResearch Source Type: research
Therapeutic index improvement of antibody-drug conjugates
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - July 6, 2023 Category: Biomedical Science Authors: Hans-Peter GerberSanjeev GangwarAlison Bettsa Department of Research and Development, Codeable Therapeutics, Palo Alto, CA, USAb Department of DMPK & Modeling, Applied BioMath, Concord, MA, USAc Department of DMPK & Modeling, Preclinical & Translationa Source Type: research
Improved antibody pharmacokinetics by disruption of contiguous positive surface potential and charge reduction using alternate human framework
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - July 6, 2023 Category: Biomedical Science Authors: Romain Ollier Aline Fuchs Florence Gauye Katarzyna Piorkowska S ébastien Menant Monisha Ratnam Paolo Montanari Florence Guilhot Didier Phillipe Mickael Audrain Anne-Laure Egesipe Damien N évoltris Tamara Seredenina Andrea Pfeifer Marie Kosco-Vilbois Tar Source Type: research
Therapeutic index improvement of antibody-drug conjugates
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - July 6, 2023 Category: Biomedical Science Authors: Hans-Peter Gerber Sanjeev Gangwar Alison Betts Source Type: research
Evidence of variable human Fc γ receptor-Fc affinities across differentially-complexed IgG
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - July 5, 2023 Category: Biomedical Science Authors: Andrew R. CrowleyMatthew R. MehlenbacherMohammad M. SajadiAnthony L. DeVicoGeorge K. LewisMargaret E. Ackermana Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Dartmouth College, Hanover, NH, USAb Department of Chemistry Source Type: research
Manufacturability and functionality assessment of different formats of T-cell engaging bispecific antibodies
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - July 5, 2023 Category: Biomedical Science Authors: Han Ping LohFarouq Bin MahfutSerene W ChenYuhan HuangJianxin HuoWei ZhangKong Peng LamShengli XuYuansheng Yanga Bioprocessing Technology Institute (BTI), Agency for Science, Technology and Research (A*STAR), Singapore, Singaporeb Singapore Immunology Netw Source Type: research
Evidence of variable human Fc γ receptor-Fc affinities across differentially-complexed IgG
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - July 5, 2023 Category: Biomedical Science Authors: Andrew R. Crowley Matthew R. Mehlenbacher Mohammad M. Sajadi Anthony L. DeVico George K. Lewis Margaret E. Ackerman Source Type: research
Manufacturability and functionality assessment of different formats of T-cell engaging bispecific antibodies
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - July 5, 2023 Category: Biomedical Science Authors: Han Ping Loh Farouq Bin Mahfut Serene W Chen Yuhan Huang Jianxin Huo Wei Zhang Kong Peng Lam Shengli Xu Yuansheng Yang Source Type: research
