Characterization of high-molecular weight by-products in the production of a trivalent bispecific 2+1 heterodimeric antibody
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - February 17, 2023 Category: Biomedical Science Authors: Dario A. T. Cramer Vojtech Franc Anna-Katharina Heidenreich Michaela Hook Mahdi Adibzadeh Dietmar Reusch Albert J. R. Heck Markus Haberger Source Type: research

Deciphering cross-species reactivity of LAMP-1 antibodies using deep mutational epitope mapping and AlphaFold
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - February 17, 2023 Category: Biomedical Science Authors: Tiphanie Pruvost Magali Mathieu Steven Dubois Bernard Maill ère Emmanuelle Vigne Herv é Nozach Source Type: research

TRYBE ®: an Fc-free antibody format with three monovalent targeting arms engineered for long in vivo half-life
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - February 15, 2023 Category: Biomedical Science Authors: Emma Dav éOliver DurrantNeha DhamiJoanne CompsonJanice BroadbridgeSophie ArcherAsher MaroofKevin WhaleKarelle MenochetPierre BonnaillieEmily BarryGavin WildClaude PeerboomPallavi BhattaMark EllisMatthew HinchliffeDavid P. HumphreysSam P. Heywooda Early S Source Type: research

Challenges in antibody structure prediction
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - February 13, 2023 Category: Biomedical Science Authors: Monica L. Fern ández-QuinteroJanik KokotFranz WaiblAnna-Lena M. FischerPatrick K. QuoikaCharlotte M. DeaneKlaus R. Liedla Department of General, Inorganic and Theoretical Chemistry, University of Innsbruck, Innsbruck, Austriab Center for Protein Assembli Source Type: research

The emerging landscape of novel 4-1BB (CD137) agonistic drugs for cancer immunotherapy
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - February 2, 2023 Category: Biomedical Science Authors: Christina ClausClaudia Ferrara-KollerChristian KleinRoche Innovation Center Zurich, Roche Pharma Research and Early Development (pRED), Schlieren, Switzerland Source Type: research

Bispecific antibody CAP256.J3LS targets V2-apex and CD4-binding sites with high breadth and potency
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - February 2, 2023 Category: Biomedical Science Authors: Baoshan ZhangJason GormanYoung D. KwonAmarendra PeguCara W. ChaoTracy LiuMangaiarkarasi AsokanMichael F. BenderTatsiana BylundLeland DamronDeepika GollapudiPaula LeiYile LiCuiping LiuMark K. LouderKrisha McKeeAdam S. OliaReda RawiArne Sch önShuishu WangE Source Type: research

The emerging landscape of novel 4-1BB (CD137) agonistic drugs for cancer immunotherapy
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - February 2, 2023 Category: Biomedical Science Authors: Christina Claus Claudia Ferrara-Koller Christian Klein Source Type: research

Predictive modeling of concentration-dependent viscosity behavior of monoclonal antibody solutions using artificial neural networks
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - January 27, 2023 Category: Biomedical Science Authors: Jonathan SchmittAbbas RazviChristoph GrapentinLonza AG/Ltd, Drug Product Services, Basel, Switzerland Source Type: research

Toward generalizable prediction of antibody thermostability using machine learning on sequence and structure features
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - January 23, 2023 Category: Biomedical Science Authors: Ameya HarmalkarRoshan RaoYuxuan Richard XieJonas HonerWibke DeistingJonas AnlahrAnja HoenigJulia CzwiklaEva Sienz-WidmannDoris RauAustin J. RiceTimothy P. RileyDanqing LiHannah B. CatterallChristine E. TinbergJeffrey J. GrayKathy Y. Weia Department of Che Source Type: research

Selection of target-binding proteins from the information of weakly enriched phage display libraries by deep sequencing and machine learning
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - January 23, 2023 Category: Biomedical Science Authors: Tomoyuki ItoThuy Duong NguyenYutaka SaitoYoichi KurumidaHikaru NakazawaSakiya KawadaHafumi NishiKoji TsudaTomoshi KamedaMitsuo Umetsua Department of Biomolecular Engineering, Graduate School of Engineering, Tohoku University, Sendai, Japanb Artificial Int Source Type: research

Correlated analytical and functional evaluation of higher order structure perturbations from oxidation of NISTmAb
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - January 23, 2023 Category: Biomedical Science Authors: Tsega L. SolomonFrank DelaglioJohn P. GiddensJohn P. MarinoYihua Bruce YuMarc B. TarabanRobert G. Brinsona Institute for Bioscience and Biotechnology Research, National Institute of Standards and Technology and the University of Maryland, Rockville, Maryl Source Type: research