An affinity threshold for maximum efficacy in anti-PD-1 immunotherapy
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - August 4, 2022 Category: Biomedical Science Authors: Sarah C. Cowles Allison Sheen Luciano Santollani Emi A. Lutz Brianna M. Lax Joseph R. Palmeri Gordon J. Freeman K. Dane Wittrup Source Type: research
Discovery and engineering of an anti-TREM2 antibody to promote amyloid plaque clearance by microglia in 5XFAD mice
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - August 3, 2022 Category: Biomedical Science Authors: Peng Zhao Yuanzhong Xu Xuejun Fan Leike Li Xin Li Hisashi Arase Qingchun Tong Ningyan Zhang Zhiqiang An Source Type: research
Development of novel ultra-sensitive IL-11 target engagement assays to support mechanistic PK/PD modeling for an anti-IL-11 antibody therapeutic
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - August 2, 2022 Category: Biomedical Science Authors: Maria Myzithras Siqi Lin Legairre Radden Cynthia Hess Kenny Zheng Cai Angus MacDonald Ralph Binetti Michael Marlow Paul Fracasso Glenn Gibson Christina Bartlett Julie Hawkins Steven Hansel Source Type: research
Extending the capabilities of intact-mass analyses to monoclonal immunoglobulins of the E-isotype (IgE)
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - July 27, 2022 Category: Biomedical Science Authors: Wenhua Yang Daniil G. Ivanov Igor A. Kaltashov Source Type: research
TNB-738, a biparatopic antibody, boosts intracellular NAD+ by inhibiting CD38 ecto-enzyme activity
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - July 22, 2022 Category: Biomedical Science Authors: Harshad S. Ugamraj Kevin Dang Laure-H élène Ouisse Benjamin Buelow Eduardo N. Chini Giulia Castello James Allison Starlynn C Clarke Laura M. Davison Roland Buelow Rong Deng Suhasini Iyer Ute Schellenberger Sankar N. Manika Shipra Bijpuria Astrid Musnier Source Type: research
Effect of molecular size on interstitial pharmacokinetics and tissue catabolism of antibodies
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - July 22, 2022 Category: Biomedical Science Authors: Hanine Rafidi Sharmila Rajan Konnie Urban Whitney Shatz-Binder Keliana Hui Gregory Z. Ferl Amrita V. Kamath C. Andrew Boswell Source Type: research
Antibody markup language (AbML) — a notation language for antibody-based drug formats and software for creating and rendering AbML (abYdraw)
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - July 15, 2022 Category: Biomedical Science Authors: James Sweet-Jones Maham Ahmad Andrew C.R. Martin Source Type: research
High-throughput profiling of antibody self-association in multiple formulation conditions by PEG stabilized self-interaction nanoparticle spectroscopy
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - July 13, 2022 Category: Biomedical Science Authors: Samantha Phan Auralee Walmer Eudean W. Shaw Qing Chai Source Type: research
A versatile design platform for glycoengineering therapeutic antibodies
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - July 9, 2022 Category: Biomedical Science Authors: Seth D. Ludwig Zachary J. Bernstein Christian Agatemor Kris Dammen-Brower Jeffrey Ruffolo Jonah M. Rosas Jeremy D. Post Robert N. Cole Kevin J. Yarema Jamie B. Spangler Source Type: research
Mechanistic insights into the rational design of masked antibodies
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - July 8, 2022 Category: Biomedical Science Authors: Carolina T. Orozco Manuela Bersellini Lorraine M. Irving Wesley W. Howard David Hargreaves Paul W. A. Devine Elise Siouve Gareth J. Browne Nicholas J. Bond Jonathan J. Phillips Peter Ravn Sophie E. Jackson Source Type: research
Separating clinical antibodies from repertoire antibodies, a path to in silico developability assessment
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - June 30, 2022 Category: Biomedical Science Authors: Christopher Negron Joyce Fang Michael J. McPherson W. Blaine Stine Andrew J. McCluskey Source Type: research
Engineering death resistance in CHO cells for improved perfusion culture
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - June 23, 2022 Category: Biomedical Science Authors: Michael A. MacDonald Matthias N öbel Ver ónica S. Martínez Kym Baker Evan Shave Peter P. Gray Stephen Mahler Trent Munro Lars K. Nielsen Esteban Marcellin Source Type: research
Antigenic landscapes on Staphylococcus aureus pore-forming toxins reveal insights into specificity and cross-neutralization
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - June 22, 2022 Category: Biomedical Science Authors: Shweta Kailasan Ravi Kant Madeleine Noonan-Shueh Tulasikumari Kanipakala Grant Liao Sergey Shulenin Daisy W. Leung Richard A. Alm Rajan P. Adhikari Gaya K. Amarasinghe Michael L. Gross M. Javad Aman Source Type: research
Development of disulfide-stabilized Fabs for targeting of antibody-directed nanotherapeutics
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - June 16, 2022 Category: Biomedical Science Authors: Melissa L. Geddie Dmitri B. Kirpotin Neeraj Kohli Tad Kornaga Bjoern Boll Maja Razlog Daryl C. Drummond Alexey A. Lugovskoy Source Type: research
In vitro discovery of a human monoclonal antibody that neutralizes lethality of cobra snake venom
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - June 14, 2022 Category: Biomedical Science Authors: Line Ledsgaard Andreas H. Laustsen Urska Pus Jack Wade Pedro Villar Kim Boddum Peter Slavny Edward W. Masters Ana S. Arias Saioa Oscoz Daniel T. Griffiths Alice M. Luther Majken Lindholm Rachael A. Leah Marie Sofie M øller Hanif Ali John McCafferty Bruno Source Type: research
