GlycoVHH: optimal sites for introducing N-glycans on the camelid VHH antibody scaffold and use for macrophage delivery
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - May 22, 2023 Category: Biomedical Science Authors: Loes van Schie Wander Van Breedam Charlotte Roels Bert Schepens Martin Frank Ahmad Reza Mehdipour Bram Laukens Wim Nerinckx Francis Santens Simon Devos Iebe Rossey Karel Thooft Sandrine Vanmarcke Annelies Van Hecke Xavier Saelens Nico Callewaert Source Type: research

High concentration formulation developability approaches and considerations
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - May 16, 2023 Category: Biomedical Science Authors: Jonathan ZarzarTarik KhanManiraj BhagawatiBenjamin WeicheJasmin Sydow-AndersenAlavattam Sreedharaa Pharmaceutical Development, Genentech Inc, South San Francisco, CA, USAb Pharma Technical Development Europe, F. Hoffmann-La Roche Ltd, Basel, Switzerlandc Source Type: research

Izokibep: Preclinical development and first-in-human study of a novel IL-17A neutralizing Affibody molecule in patients with plaque psoriasis
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - May 15, 2023 Category: Biomedical Science Authors: Susanne KlintJoachim FeldwischLindvi GudmundsdotterKarin Dillner BergstedtElin GunneriussonIngmarie H öidén GuthenbergAnders WennborgAndrew C. NyborgAmol P. KambojPaul M. PelosoDavid BejkerFredrik Y. Frejda Affibody AB, Solna, Swedenb ACELYRIN, Agoura H Source Type: research

10th antibody industrial symposium: new developments in antibody and adoptive cell therapies
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - May 15, 2023 Category: Biomedical Science Authors: Ana AntunesLuis Alvarez-VallinaFederico BertoglioNicolas BouquinSt éphanie CornenFrancis DuffieuxPierre FerréRaphaëlle GilletChristian JorgensenMark B LeickBernard MaillèreHélène NegreMireia PelegrinNicolas PoirierDietmar ReuschBruno RobertGuy Serre Source Type: research

Izokibep: Preclinical development and first-in-human study of a novel IL-17A neutralizing Affibody molecule in patients with plaque psoriasis
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - May 15, 2023 Category: Biomedical Science Authors: Susanne Klint Joachim Feldwisch Lindvi Gudmundsdotter Karin Dillner Bergstedt Elin Gunneriusson Ingmarie H öidén Guthenberg Anders Wennborg Andrew C. Nyborg Amol P. Kamboj Paul M. Peloso David Bejker Fredrik Y. Frejd Source Type: research

Engaging natural killer cells for cancer therapy via NKG2D, CD16A and other receptors
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - May 11, 2023 Category: Biomedical Science Authors: Kerry A. WhalenKavya RakhraNaveen K. MehtaAlexander SteinleJennifer S. MichaelsonPatrick A. Baeuerlea Preclinical and Early Development, Cullinan Oncology, Inc, Cambridge, MA, USAb Institute for Molecular Medicine, Goethe-University Frankfurt, Frankfurt a Source Type: research

VERITAS: Harnessing the power of nomenclature in biologic discovery
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - May 10, 2023 Category: Biomedical Science Authors: Riti BiswasEd BelouskiKevin GrahamMichelle HortterMarissa MockChristine E. TinbergAlan J. Russella Biologic Therapeutic Discovery, Amgen Research, South San Francisco, CA, USAb Biologic Therapeutic Discovery, Amgen Research, Thousand Oaks, CA, USA Source Type: research

Identifying developability risks for clinical progression of antibodies using high-throughput in vitro and in silico approaches
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - April 19, 2023 Category: Biomedical Science Authors: Tushar JainTodd BolandMaximiliano V ásqueza Adimab LLC, Palo Alto, CA, USAb Computational Biology, Adimab LLC, Lebanon, NH, USA Source Type: research

“Stapling” scFv for multispecific biotherapeutics of superior properties
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - April 19, 2023 Category: Biomedical Science Authors: Lauren E. BoucherElisabeth Geyer PrinslowMichael FeldkampFang YiRupesh NanjundaSheng-Jiun WuTun LiuEilyn R. LacySteven JacobsNatalia KozlyukBrian Del RosarioBingyuan WuPatricia AquinoRobert C. DavidsonSamantha HeyneNicholas MazzantiJames TestaMichael D. D Source Type: research

Identifying developability risks for clinical progression of antibodies using high-throughput in vitro and in silico approaches
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - April 19, 2023 Category: Biomedical Science Authors: Tushar Jain Todd Boland Maximiliano V ásquez Source Type: research