Cadonilimab, a tetravalent PD-1/CTLA-4 bispecific antibody with trans-binding and enhanced target binding avidity
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - March 6, 2023 Category: Biomedical Science Authors: Xinghua PangZhaoliang HuangTingting ZhongPeng ZhangZhongmin Maxwell WangMichelle XiaBaiyong LiResearch and Development Department, Akeso Biopharma, Inc, Zhongshan, China Source Type: research

eIg-based bispecific T-cell engagers targeting EGFR: Format matters
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - March 3, 2023 Category: Biomedical Science Authors: Lennart K ühlAnnelie K. SchäferSebastian KraftNadine AschmoneitRoland E. KontermannOliver Seiferta Institute of Cell Biology and Immunology, University of Stuttgart, Stuttgart, Germanyb Stuttgart Research Center Systems Biology (SRCSB), University of St Source Type: research

High-throughput optofluidic screening of single B cells identifies novel cross-reactive antibodies as inhibitors of uPAR with antibody-dependent effector functions
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - March 2, 2023 Category: Biomedical Science Authors: Andr é Luiz LourençoShih-Wei ChuoMarkus F. BohnByron HannShireen KhanNeha YevalekarNitin PatelTeddy YangLina XuDandan LvRobert DrakasSarah LivelyCharles S. Craika Department of Pharmaceutical Chemistry, University of California San Francisco, San Franci Source Type: research

Assessing developability early in the discovery process for novel biologics
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - February 24, 2023 Category: Biomedical Science Authors: Monica L. Fern ández-QuinteroAnne LjungarsFranz WaiblVictor GreiffJan Terje AndersenTorleif T. GjølbergTimothy P. JenkinsBjørn Gunnar VoldborgLise Marie GravSandeep KumarGuy GeorgesHubert KettenbergerKlaus R. LiedlPeter M. TessierJohn McCaffertyAndreas Source Type: research

Strategies for clinical dose optimization of T cell-engaging therapies in oncology
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - February 24, 2023 Category: Biomedical Science Authors: Kathryn BallSimon J DovediPavan VajjahAlex Phippsa Clinical Pharmacology and Quantitative Pharmacology, Biopharmaceuticals R & D, AstraZeneca, Cambridge, UKb Early Oncology R & D, AstraZeneca, Cambridge, UK Source Type: research

Assessing developability early in the discovery process for novel biologics
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - February 24, 2023 Category: Biomedical Science Authors: Monica L. Fern ández-Quintero Anne Ljungars Franz Waibl Victor Greiff Jan Terje Andersen Torelif T. Gj ølberg Timothy P. Jenkins Bj ørn Gunnar Voldborg Lise Marie Grav Sandeep Kumar Guy Georges Hubert Kettenberger Klaus R. Liedl Peter M. Tessier John M Source Type: research

SpyDisplay: A versatile phage display selection system using SpyTag/SpyCatcher technology
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - February 21, 2023 Category: Biomedical Science Authors: Sarah-Jane KellmannChristian HentrichMateusz PutyrskiHanh HanuschkaManuel CavadaAchim KnappikFrancisco YleraBio-Rad AbD Serotec GmbH, Neuried, Germany Source Type: research

Characterization of high-molecular weight by-products in the production of a trivalent bispecific 2+1 heterodimeric antibody
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - February 17, 2023 Category: Biomedical Science Authors: Dario A. T. CramerVojtech FrancAnna-Katharina HeidenreichMichaela HookMahdi AdibzadehDietmar ReuschAlbert J. R. HeckMarkus Habergera Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmace Source Type: research

Deciphering cross-species reactivity of LAMP-1 antibodies using deep mutational epitope mapping and AlphaFold
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - February 17, 2023 Category: Biomedical Science Authors: Tiphanie PruvostMagali MathieuSteven DuboisBernard Maill èreEmmanuelle VigneHervé Nozacha CEA, INRAE, Medicines and Healthcare Technologies Department, Université Paris-Saclay, SIMoS, Franceb Sanofi, Large Molecule Research, Vitry-sur-Seine, Francec Sa Source Type: research