Multivalent design of the monoclonal SynO2 antibody improves binding strength to soluble α-Synuclein aggregates
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - September 22, 2023 Category: Biomedical Science Authors: Inga PetersenMuhammad Ilyas AliAlex PetrovicAnders Jimmy YtterbergKarin Stax ängMonika HodikFadi RofoSina BondzaGreta Hultqvista Department of Pharmacy, Uppsala University, Uppsala, Swedenb Department of Pharmacy, SciLifeLab Drug Discovery and Developmen Source Type: research

Development of in silico models to predict viscosity and mouse clearance using a comprehensive analytical data set collected on 83 scaffold-consistent monoclonal antibodies
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - September 12, 2023 Category: Biomedical Science Authors: Marissa MockAlex W. JacobitzChristopher James LangmeadAthena SudomDaniel YooSara C. HumphreysMai AldayLarysa AlekseychykNicolas AngellVivian BiHannah CatterallChen-Chun ChenHui-Ting ChouKip P. ConnerKevin D. CookAna R. CorreiaAndrew DykstraSudipa Ghimire- Source Type: research

Discovery and characterization of prolactin neutralizing monoclonal antibodies for the treatment of female-prevalent pain disorders
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - September 12, 2023 Category: Biomedical Science Authors: Stephanie MaciubaGregory D. BowdenHarrison J. StrattonKazimierz WisniewskiClaudio D. SchteingartJuan C. AlmagroPhilippe ValadonJoshua LowitzScott M. GlaserGrace LeeMahdi DolatyariEdita NavratilovaFrank PorrecaPierre J.M. Rivi èrea Peptide Logic, San Dieg Source Type: research

Development of in silico models to predict viscosity and mouse clearance using a comprehensive analytical data set collected on 83 scaffold-consistent monoclonal antibodies
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - September 12, 2023 Category: Biomedical Science Authors: Marissa Mock Alex W. Jacobitz Christopher James Langmead Athena Sudom Daniel Yoo Sara C. Humphreys Mai Alday Larysa Alekseychyk Nicolas Angell Vivian Bi Hannah Catterall Chen-Chun Chen Hui-Ting Chou Kip P. Conner Kevin D. Cook Ana R. Correia Andrew Dykstr Source Type: research

Discovery and characterization of prolactin neutralizing monoclonal antibodies for the treatment of female-prevalent pain disorders
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - September 12, 2023 Category: Biomedical Science Authors: Stephanie Maciuba Gregory D. Bowden Harrison J. Stratton Kazimierz Wisniewski Claudio D. Schteingart Juan C. Almagro Philippe Valadon Joshua Lowitz Scott M. Glaser Grace Lee Mahdi Dolatyari Edita Navratilova Frank Porreca Pierre J.M. Rivi ère Source Type: research

Rapid in vitro assessment of the immunogenicity potential of engineered antibody therapeutics through detection of CD4+ T cell interleukin-2 secretion
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - September 8, 2023 Category: Biomedical Science Authors: Yoshiyuki ArataShigeki MotoyamaMariko YanoTatsuya IkunoShunsuke ItoTomochika MatsushitaAkira TakeiriYukari NishitoNami YabukiHideaki MizunoZenjiro SampeiMasayuki MishimaMasaki HondaJumpei KiyokawaHiromi SuzukiShuichi ChibaMitsuyasu TaboChiyomi Kuboa Trans Source Type: research

Biophysical characterization of PVR family interactions and therapeutic antibody recognition to TIGIT
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - September 7, 2023 Category: Biomedical Science Authors: SJ J. DiongAarti JashnaniAndrew W. DrakeChristine BeeFelix FindeisenGavin DollingerFeng WangArvind RajpalPavel StropPeter S. Leea Discovery Biologics, Bristol Myers Squibb, Redwood City, CA, USAb Biochemistry and Biophysics, Merck, South San Francisco, CA Source Type: research

Mammalian display to secretion switchable libraries for antibody preselection and high throughput functional screening
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - August 30, 2023 Category: Biomedical Science Authors: Ramona GaaHannah Melina MayerDaniela NoackKavita KumariRalf GuentherShang-Pu TsaiQingyong JiAchim Doernera NBE Technologies, Merck KGaA, Darmstadt, Germanyb Discovery Biology, Syngene International, Bangalore, Indiac NBE Technologies, EMD Serono, Billeric Source Type: research

Use of poxvirus display to select antibodies specific for complex membrane antigens
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - August 28, 2023 Category: Biomedical Science Authors: Ernest S. SmithLeslie A. BalchMaria ScrivensShuying ShiWei WangCaroline D. HarveyAngelica A. CornelisonMalgorzata Gil-MooreRenee A. KirkLoretta L. MuellerRichard L. HallAlan P. HowellChristine A. ReillyJessica M. MayerFrancis G. MuranteKari A ViggianiElai Source Type: research

Exploration of the antibody –drug conjugate clinical landscape
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - August 28, 2023 Category: Biomedical Science Authors: Heather MaeckerVidya JonnalagaddaSunil BhaktaVasu JammalamadakaJagath R. JunutulaAarvik Therapeutics, Inc, Hayward, CA, USA Source Type: research