A mouse pancreatic organoid model to compare PD-L1 blocking antibodies
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - November 5, 2022 Category: Biomedical Science Authors: Guangyuan Li Susmita Ghosh JuMe Park Hyunsu Shin Mamatha Garige Gregory Reaman Carole Sourbier Source Type: research

Insights into ultra-low affinity lipase-antibody noncovalent complex binding mechanisms
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - October 26, 2022 Category: Biomedical Science Authors: Elizabeth Sara Hecht Shrenik Mehta Aaron T. Wecksler Ben Aguilar Nathaniel Swanson Wilson Phung Ananya Dubey Kelsoe W. Henry Benner Devin Tesar Robert F. Kelley Wendy Sandoval Alavattam Sreedhara Source Type: research

Pandemic ’s silver lining
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - October 18, 2022 Category: Biomedical Science Authors: Fortunato Ferrara Sara D ’Angelo M. Frank Erasmus Andr é A. Teixeira Camila Leal-Lopes Laura P. Spector Tom Pohl Adeline Fanni Simon Cocklin Andrew R. M. Bradbury Source Type: research

Unambiguous identification of α-Gal epitopes in intact monoclonal antibodies by NMR spectroscopy
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - October 14, 2022 Category: Biomedical Science Authors: Arthur Hinterholzer Jennifer Moises Christof Regl Sebastian Schwap Erdmann Rapp Christian G. Huber Mario Schubert Source Type: research

A competitive binding-mass spectrometry strategy for high-throughput evaluation of potential critical quality attributes of therapeutic monoclonal antibodies
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - October 13, 2022 Category: Biomedical Science Authors: Zhengqi Zhang Yuetian Yan Shunhai Wang Ning Li Source Type: research

Development of T-cell engagers selective for cells co-expressing two antigens
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - October 7, 2022 Category: Biomedical Science Authors: Danielle M. Dicara Sunil Bhakta Mary Ann Go James Ziai Ron Firestein Bill Forrest Chen Gu Steven R. Leong Genee Lee Shang-Fan Yu Andrew G. Polson Nicholas J. Agard Source Type: research

Fast-tracking antibody maturation using a B cell-based display system
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - October 7, 2022 Category: Biomedical Science Authors: Hitomi Masuda Atsushi Sawada Shu-ichi Hashimoto Kanako Tamai Ke-Yi Lin Naoto Harigai Kohei Kurosawa Kunihiro Ohta Hidetaka Seo Hiroshi Itou Source Type: research

The impact of forced degradation conditions on mAb dimer formation and subsequent influence on aggregation propensity
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - October 5, 2022 Category: Biomedical Science Authors: Michael J. Knight L éontine Floret Nisha Patel John O ’Hara Elizabeth Rodriguez Source Type: research

Investigating protein –excipient interactions of a multivalent VHH therapeutic protein using NMR spectroscopy
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - September 27, 2022 Category: Biomedical Science Authors: Jainik Panchal Bradley T. Falk Valentyn Antochshuk Mark A. McCoy Source Type: research

Physicochemical and biological impact of metal-catalyzed oxidation of IgG1 monoclonal antibodies and antibody-drug conjugates via reactive oxygen species
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - September 24, 2022 Category: Biomedical Science Authors: Zephania Kwong Glover Aaron Wecksler Baikuntha Aryal Shrenik Mehta Melissa Pegues Wayman Chan Mari Lehtimaki Allen Luo Alavattam Sreedhara V. Ashutosh Rao Source Type: research

Systematic analysis of the varied designs of 819 therapeutic antibodies and Fc fusion proteins assigned international nonproprietary names
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - September 16, 2022 Category: Biomedical Science Authors: Ian Wilkinson Geoff Hale Source Type: research

Simultaneous affinity maturation and developability enhancement using natural liability-free CDRs
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - September 7, 2022 Category: Biomedical Science Authors: Andre A. R. Teixeira Sara D ’Angelo M. Frank Erasmus Camila Leal-Lopes Fortunato Ferrara Laura P. Spector Leslie Naranjo Esteban Molina Tamara Max Ashley DeAguero Katherine Perea Shaun Stewart Rebecca A. Buonpane Horacio G. Nastri Andrew R. M. Bradbury Source Type: research

Liposomal T cell engager and re-director for tumor cell eradication in cancer immunotherapy
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - August 30, 2022 Category: Biomedical Science Authors: Fang Xie Luchen Zhang Sanyuan Shi Anjie Zheng Jiaxing Di Shanshan Jin Xuguang Miao Fenglan Wu Xiaolong Chen Yanhong Zhang Xiaohui Wei Yuhong Xu Source Type: research

Full-length recombinant antibodies from Escherichia coli: production, characterization, effector function (Fc) engineering, and clinical evaluation
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - August 26, 2022 Category: Biomedical Science Authors: Md Harunur Rashid Source Type: research

NAb-seq: an accurate, rapid, and cost-effective method for antibody long-read sequencing in hybridoma cell lines and single B cells
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - August 13, 2022 Category: Biomedical Science Authors: Hema Preethi Subas Satish Kathleen Zeglinski Rachel T. Uren Stephen L. Nutt Matthew E. Ritchie Quentin Gouil Ruth M. Kluck Source Type: research