A perspective toward mass spectrometry-based de novo sequencing of endogenous antibodies
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - June 14, 2022 Category: Biomedical Science Authors: Sebastiaan C. de Graaf Max Hoek Sem Tamara Albert J. R. Heck Source Type: research

Enzymatic glycan remodeling –metal free click (GlycoConnect™) provides homogenous antibody-drug conjugates with improved stability and therapeutic index without sequence engineering
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - May 29, 2022 Category: Biomedical Science Authors: Marloes A. Wijdeven Remon van Geel Jorin H. Hoogenboom Jorge M. M. Verkade Brian M. G. Janssen Inge Hurkmans Laureen de Bever Sander S. van Berkel Floris L. van Delft Source Type: research

The proximity of the N- and C- termini of bovine knob domains enable engineering of target specificity into polypeptide chains
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - May 29, 2022 Category: Biomedical Science Authors: Alice Hawkins Callum Joyce Kevin Brady Adam Hold Alan Smith Michael Knight Conor Howard Jean van den Elsen Alastair D.G. Lawson Alex Macpherson Source Type: research

An adapted consensus protein design strategy for identifying globally optimal biotherapeutics
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - May 25, 2022 Category: Biomedical Science Authors: Yanyun Liu Kenny Tsang Michelle Mays Gale Hansen Jeffrey Chiecko Maureen Crames Yangjie Wei Weijie Zhou Chase Fredrick James Hu Dongmei Liu Douglas Gebhard Zhong-Fu Huang Akshita Datar Anthony Kronkaitis Kristina Gueneva-Boucheva Daniel Seeliger Fei Han S Source Type: research

Deep mutational engineering of broadly-neutralizing nanobodies accommodating SARS-CoV-1 and 2 antigenic drift
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - May 20, 2022 Category: Biomedical Science Authors: Adrien Laroche Maria Lucia Orsini Delgado Benjamin Chalopin Philippe Cuniasse Steven Dubois Rapha ël Sierocki Fabrice Gallais St éphanie Debroas Laurent Bellanger St éphanie Simon Bernard Maill ère Herv é Nozach Source Type: research

International nonproprietary names for monoclonal antibodies: an evolving nomenclature system
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - May 18, 2022 Category: Biomedical Science Authors: Sofia S. Guimaraes Koch Robin Thorpe Nana Kawasaki Marie-Paule Lefranc Sarel Malan Andrew C.R. Martin Gilles Mignot Andreas Pl ückthun Menico Rizzi Stephanie Shubat Karin Weisser Raffaella Balocco Source Type: research

The human antibody sequence space and structural design of the V, J regions, and CDRH3 with Rosetta
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - May 11, 2022 Category: Biomedical Science Authors: Samuel Schmitz Emily A. Schmitz James E. Crowe Jens Meiler Source Type: research

Novel super-neutralizing antibody UT28K is capable of protecting against infection from a wide variety of SARS-CoV-2 variants
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - May 11, 2022 Category: Biomedical Science Authors: Tatsuhiko Ozawa Hideki Tani Yuki Anraku Shunsuke Kita Emiko Igarashi Yumiko Saga Noriko Inasaki Hitoshi Kawasuji Hiroshi Yamada so-Ichiro Sasaki Mayu Somekawa Jiei Sasaki Yoshihiro Hayakawa Yoshihiro Yamamoto Yoshitomo Morinaga Nobuyuki Kurosawa Masaharu Source Type: research

Physiologically Based Modeling to Predict Monoclonal Antibody Pharmacokinetics in Humans from in vitro Physiochemical Properties
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - May 1, 2022 Category: Biomedical Science Authors: Shihao Hu Amita Datta-Mannan David Z. D ’Argenio Source Type: research

Predicting antibody binders and generating synthetic antibodies using deep learning
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - April 28, 2022 Category: Biomedical Science Authors: Yoong Wearn Lim Adam S. Adler David S. Johnson Source Type: research

Elimination of plasma soluble antigen in cynomolgus monkeys by combining pH-dependent antigen binding and novel Fc engineering
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - April 28, 2022 Category: Biomedical Science Authors: Yuji Hori Ken Ohmine Hitoshi Katada Yuki Noguchi Kazuki Sato Takeru Nambu Lam Runyi Adeline Gan Siok Wan Kenta Haraya Kazuhisa Ozeki Masahiko Nanami Tatsuhiko Tachibana Zenjiro Sampei Taichi Kuramochi Junichi Nezu Kunihiro Hattori Tomoyuki Igawa Source Type: research

Development of QSAR models for in silico screening of antibody solubility
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - April 20, 2022 Category: Biomedical Science Authors: Xuan Han James Shih Yuhao Lin Qing Chai Steven M. Cramer Source Type: research

The eIg technology to generate Ig-like bispecific antibodies
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - April 15, 2022 Category: Biomedical Science Authors: Lennart K ühl Nadine Aschmoneit Roland E. Kontermann Oliver Seifert Source Type: research

Enhanced anti-angiogenetic effect of transferrin receptor-mediated delivery of VEGF-trap in a glioblastoma mouse model
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - April 7, 2022 Category: Biomedical Science Authors: Peng Zhao Yasuaki Anami Peng Gao Xuejun Fan Leike Li Kyoji Tsuchikama Ningyan Zhang Zhiqiang an Source Type: research

Upstream cell culture process characterization and in-process control strategy development at pandemic speed
Volume 14, Issue 1, January-December 2022 . (Source: mAbs)
Source: mAbs - April 5, 2022 Category: Biomedical Science Authors: Jianlin Xu Jianfa Ou Kyle P. McHugh Michael C. Borys Anurag Khetan Source Type: research