Variable domain mutational analysis to probe the molecular mechanisms of high viscosity of an IgG1 antibody
Volume 16, Issue 1, January-December 2024 . (Source: mAbs)
Source: mAbs - January 25, 2024 Category: Biomedical Science Authors: Jing DaiSaeed IzadiJonathan ZarzarPatrick WuAngela OhPaul J. Cartera Department of Antibody Engineering, Genentech, Inc, South San Francisco, CA, USAb Department of Pharmaceutical Development, Genentech, Inc, South San Francisco, CA, USAc Department of Bi Source Type: research
A tailored lectin microarray for rapid glycan profiling of therapeutic monoclonal antibodies
Volume 16, Issue 1, January-December 2024 . (Source: mAbs)
Source: mAbs - January 22, 2024 Category: Biomedical Science Authors: Shen LuoBaolin ZhangOffice of Pharmaceutical Quality, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA Source Type: research
Interactions of the anti-FcRn monoclonal antibody, rozanolixizumab, with Fc γ receptors and functional impact on immune cells in vitro
Volume 16, Issue 1, January-December 2024 . (Source: mAbs)
Source: mAbs - January 19, 2024 Category: Biomedical Science Authors: Omar S. QureshiEmma J. SuttonRosemary F. BithellShauna M. WestRona M. CutlerGillian McCluskeyGraham CraggsAsher MaroofNicholas M. BarnesDavid P. HumphreysStephen RapeckiBryan J. SmithAnthony Shocka UCB Pharma, Berkshire, UKb Celentyx Ltd, Birmingham Resea Source Type: research
Engineering hydrophobicity and manufacturability for optimized biparatopic antibody –drug conjugates targeting c-MET
Volume 16, Issue 1, January-December 2024 . (Source: mAbs)
Source: mAbs - January 12, 2024 Category: Biomedical Science Authors: Andreas EversSimon KrahDeniz DemirRamona GaaDesislava ElterChristian SchroeterStefan ZielonkaNicolas RascheJulia DotterweichChristine KnuehlAchim Doernera Antibody Discovery and Protein Engineering, Merck Healthcare KGaA, Darmstadt, Germanyb ADC and Targe Source Type: research
Antibodies to watch in 2024
Volume 16, Issue 1, January-December 2024 . (Source: mAbs)
Source: mAbs - January 5, 2024 Category: Biomedical Science Authors: Silvia CrescioliH élène KaplonAlicia ChenowethLin WangJyothsna VisweswaraiahJanice M. Reicherta Business Intelligence Research, The Antibody Society, Inc., Framingham, MA, USb Translational Medicine Department, Institut de Recherches Internationales Ser Source Type: research
Therapeutic efficacy of a potent anti-Venezuelan equine encephalitis virus antibody is contingent on Fc effector function
Volume 16, Issue 1, January-December 2024 . (Source: mAbs)
Source: mAbs - January 3, 2024 Category: Biomedical Science Authors: Jennifer L. SchwedlerMaxwell A. StefanChristine E. ThatcherPeter R. McIlroyAnupama SinhaAshlee M. PhillipsChristopher A. SumnerColleen M. CourtneyChristina Y. KimDina R. WeilhammerBrooke Harmona Biotechnology and Bioengineering Department, Sandia National Source Type: research
Comprehensive characterization of higher order structure changes in methionine oxidized monoclonal antibodies via NMR chemometric analysis and biophysical approaches
Volume 16, Issue 1, January-December 2024 . (Source: mAbs)
Source: mAbs - December 20, 2023 Category: Biomedical Science Authors: Mingyue LiVictor A. BeaumontShahajahan AkbarHannah DuncanArch CreasyWenge WangKelly SackettLisa MarzilliJason C. RouseHai-Young Kima Pfizer, Inc. BioTherapeutics Pharmaceutical Sciences, Analytical Research and Development, Andover, MA, USAb Pfizer, Inc. Source Type: research
Accelerating the speed of innovative anti-tumor drugs to first-in-human trials incorporating key de-risk strategies
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - December 14, 2023 Category: Biomedical Science Authors: Yuqi WangQuan QuanCamille GleasonHelin YuLujia PengYanshen KangLing JiangKailun WuJie PanMoxiyele BaoQing ZhuMeiqi YiMing FangYue ZhengLing QiuBin XuXiang LiJinfeng SongJiamu SunZheng ZhangZijun SuJara LinYuanyuan XieApril XuXiling SongChichi HuangZhirong Source Type: research
Determining the affinities of high-affinity antibodies using KinExA and surface plasmon resonance
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - December 13, 2023 Category: Biomedical Science Authors: M. Frank ErasmusMolly DovnerFortunato FerraraSara D ’AngeloAndré A. TeixeiraCamila Leal-LopesLaura SpectorElizabeth HopkinsAndrew R. M. Bradburya Specifica, LLC, a Q2 Solutions Company, Santa Fe, NM, USAb Sapidyne, Inc, Boise, ID, USA Source Type: research
Discovery of ginisortamab, a potent and novel anti-gremlin-1 antibody in clinical development for the treatment of cancer
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - December 12, 2023 Category: Biomedical Science Authors: Gareth C. G. DaviesNeesha DediPaul S. JonesLara KevorkianDavid McMillanCristina OttoneMonika-Sarah E. D. SchulzeAnthony Scott-TuckerRoohi TewariShauna WestMichael WrightTania F. RowleyUCB Pharma, Slough, UK Source Type: research
Breaking barriers in antibody discovery: harnessing divergent species for accessing difficult and conserved drug targets
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - December 5, 2023 Category: Biomedical Science Authors: Soma S.R. BanikNatasha KushnirBenjamin J. DoranzRoss ChambersIntegral Molecular, Philadelphia, PA, USA Source Type: research
