A novel conditional active biologic anti-EpCAM x anti-CD3 bispecific antibody with synergistic tumor selectivity for cancer immunotherapy
Volume 16, Issue 1, January-December 2024 . (Source: mAbs)
Source: mAbs - March 6, 2024 Category: Biomedical Science Authors: Gerhard FreyAna Paula G. CugnettiHaizhen LiuCharles XingChristina WheelerHwai Wen ChangWilliam J. BoyleJay M. ShortResearch & Development, BioAtla Inc, San Diego, CA, USA Source Type: research
Improving the integrity and reproducibility of research that uses antibodies: a technical, data sharing, behavioral and policy challenge
Volume 16, Issue 1, January-December 2024 . (Source: mAbs)
Source: mAbs - March 6, 2024 Category: Biomedical Science Authors: M. BiddleP. StylianouM. RekasA. WrightJ. SousaD. RuddyM. I. StefanaK. KmiecikA. BandrowskiR.A. KahnC. LaflammeE. M. KrockowH.S. Virka NIHR Respiratory BRC, Department of Respiratory Sciences, University of Leicester, Leicester, UKb JDRF/Wellcome Diabetes Source Type: research
Exploring molecular determinants and pharmacokinetic properties of IgG1-scFv bispecific antibodies
Volume 16, Issue 1, January-December 2024 . (Source: mAbs)
Source: mAbs - March 6, 2024 Category: Biomedical Science Authors: Kristina M.J. AertkerMinu Ravindra PilvankarTobias M. PrassMichaela BlechFabian HigelSrinath Kasturirangana Analytical Development Biologicals, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riss, Germanyb Biotherapeutics Discovery, Boehringe Source Type: research
Proceedings of the 14th European immunogenicity platform open symposium on immunogenicity of biopharmaceuticals
Volume 16, Issue 1, January-December 2024 . (Source: mAbs)
Source: mAbs - March 5, 2024 Category: Biomedical Science Authors: Sophie TourdotDaniel BaltrunkonisSofie DeniesViswanath DevanarayanJoanna Grudzinska-GoebelArno KrommingaGregor P. LotzLaurent MalherbeLydia MichautKarin N. WeldinghJoao A. Pedras-VasconcelosLaura. I. Salazar-FontanaSebastian SpindeldreherZuben SaunaVeerle Source Type: research
Application of quantitative protein mass spectrometric data in the early predictive analysis of membrane-bound target engagement by monoclonal antibodies
Volume 16, Issue 1, January-December 2024 . (Source: mAbs)
Source: mAbs - March 5, 2024 Category: Biomedical Science Authors: Armin SeppMorris Muliaditana Simcyp Division, Certara UK Ltd, Sheffield, UKb Leiden Experts on Advanced Pharmacokinetics and Pharmacodynamics (LAP & P), Leiden, The Netherlands Source Type: research
Biparatopic antibodies: therapeutic applications and prospects
Volume 16, Issue 1, January-December 2024 . (Source: mAbs)
Source: mAbs - March 5, 2024 Category: Biomedical Science Authors: David L. NiquilleKyle M. FitzgeraldNimish GeraBiologics, Mythic Therapeutics, Waltham, MA, USA Source Type: research
Production of antibodies and antibody fragments containing non-natural amino acids in Escherichia coli
Volume 16, Issue 1, January-December 2024 . (Source: mAbs)
Source: mAbs - February 21, 2024 Category: Biomedical Science Authors: Jacquelyn Blake-HedgesDan GroffWilson FooJeffrey HansonElenor CastilloMiao WenDiana CheungMary Rose MasikatJian LuYoung ParkNina Abi CarlosHans UsmanKevin FongAbigail YuSihong ZhouJoyce KwongCuong TranXiaofan LiDawei YuanTrevor HallamGang YinResearch and Source Type: research
Facilitating high throughput bispecific antibody production and potential applications within biopharmaceutical discovery workflows
Volume 16, Issue 1, January-December 2024 . (Source: mAbs)
Source: mAbs - February 21, 2024 Category: Biomedical Science Authors: Caitlin FawcettJoseph. R. TickleCharlotte. H. Colesa Large Molecule Discovery, GSK, GSK Medicines Research Centre, Stevenage, UKb Department of Pure and Applied Chemistry, University of Strathclyde, Glasgow, UK Source Type: research
Impact of antibody architecture and paratope valency on effector functions of bispecific NKp30 x EGFR natural killer cell engagers
Volume 16, Issue 1, January-December 2024 . (Source: mAbs)
Source: mAbs - February 19, 2024 Category: Biomedical Science Authors: Ammelie Svea BojeLukas PekarKatharina KoepBritta LipinskiBrian RabinovichAndreas EversCarina Lynn GehlertSteffen KrohnYanping XiaoSimon KrahRinat ZaynagetdinovLars ToleikisSven PoetzschMatthias PeippStefan ZielonkaKatja Klausza Division of Antibody-Based Source Type: research
Structure- and machine learning-guided engineering demonstrate that a non-canonical disulfide in an anti-PD-1 rabbit antibody does not impede antibody developability
Volume 16, Issue 1, January-December 2024 . (Source: mAbs)
Source: mAbs - February 15, 2024 Category: Biomedical Science Authors: Wei-Ching LiangHongkang XiDawei SunLuigi D ’AscenzoJonathan ZarzarNicole StephensRyan CookYinyin LiZhengmao YeMarissa MatsumotoJian PayandehMatthieu MasureelYan Wua Department of Antibody Engineering, Genentech Inc, South San Francisco, CA, USAb Departm Source Type: research
CC-96673 (BMS-986358), an affinity-tuned anti-CD47 and CD20 bispecific antibody with fully functional fc, selectively targets and depletes non-Hodgkin ’s lymphoma
Volume 16, Issue 1, January-December 2024 . (Source: mAbs)
Source: mAbs - February 13, 2024 Category: Biomedical Science Authors: Dan ZhuHaralambos HadjivassiliouCatherine JenningsDavid MikolonMassimo AmmiranteSharmistha AcharyaJon LloydMahan AbbasianRama Krishna NarlaJoseph R. PiccottiKatie StampHo ChoKandasamy Hariharana Department of Discovery Biotherapeutics, Bristol Myers Squib Source Type: research
Electrostatic properties of human germlines and biodistribution of small biologics
Volume 16, Issue 1, January-December 2024 . (Source: mAbs)
Source: mAbs - February 9, 2024 Category: Biomedical Science Authors: Leticia Maria De Souza CordeiroKelley Christine AtkinsonArgin AivazianPatrick Frank JoyceFang JiaAlessandro Mascionia Preclinical discovery, ImaginAb, Inc, Inglewood, CA, USAb Cell biology, Skye Biologics, El Segundo, CA, USA Source Type: research
Charge heterogeneity of therapeutic monoclonal antibodies by different cIEF systems: views on the current situation
Volume 16, Issue 1, January-December 2024 . (Source: mAbs)
Source: mAbs - February 9, 2024 Category: Biomedical Science Authors: Alessandro AscioneMarcello BelfioreJaana VesterinenMihaela BudaWolf HoltkampFrancesca Luciania National Centre for the Control and Evaluation of Medicines, Istituto Superiore di Sanit à, Rome, Italyb National Centre for Drug Research and Evaluation, Isti Source Type: research
Correction
Volume 16, Issue 1, January-December 2024 . (Source: mAbs)
Source: mAbs - February 8, 2024 Category: Biomedical Science Source Type: research
In-situ biophysical characterization of high-concentration protein formulations using wNMR
Volume 16, Issue 1, January-December 2024 . (Source: mAbs)
Source: mAbs - February 1, 2024 Category: Biomedical Science Authors: Jing SongMarc TarabanY. Bruce YuLynn LuPallavi Guha BiswasWei XuHanmi XiAkhilesh BhambhaniGuangli HuYongchao Sua Analytical Research and Development, Merck & Co., Inc, Rahway, NJ, USAb University of Maryland School of Pharmacy and Institute for Bioscienc Source Type: research
