Selection of target-binding proteins from the information of weakly enriched phage display libraries by deep sequencing and machine learning
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - January 23, 2023 Category: Biomedical Science Authors: Tomoyuki Ito Thuy Duong Nguyen Yutaka Saito Yoichi Kurumida Hikaru Nakazawa Sakiya Kawada Hafumi Nishi Koji Tsuda Tomoshi Kameda Mitsuo Umetsu Source Type: research

Toward generalizable prediction of antibody thermostability using machine learning on sequence and structure features
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - January 23, 2023 Category: Biomedical Science Authors: Ameya Harmalkar Roshan Rao Yuxuan Richard Xie Jonas Honer Wibke Deisting Jonas Anlahr Anja Hoenig Julia Czwikla Eva Sienz-Widmann Doris Rau Austin J. Rice Timothy P. Riley Danqing Li Hannah B. Catterall Christine E. Tinberg Jeffrey J. Gray Kathy Y. Wei Source Type: research

Correlated analytical and functional evaluation of higher order structure perturbations from oxidation of NISTmAb
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - January 23, 2023 Category: Biomedical Science Authors: Tsega L. Solomon Frank Delaglio John P. Giddens John P. Marino Yihua Bruce Yu Marc B. Taraban Robert G. Brinson Source Type: research

Approaches to expand the conventional toolbox for discovery and selection of antibodies with drug-like physicochemical properties
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - January 11, 2023 Category: Biomedical Science Authors: Hristo L. SvilenovPaolo ArosioTim MenzenPeter TessierPietro Sormannia Laboratory of General Biochemistry and Physical Pharmacy, Faculty of Pharmaceutical Sciences, Ghent University, Gent, Belgiumb Department of Chemistry and Applied Biosciences, ETH Z ür Source Type: research

HDX-MS study on garadacimab binding to activated FXII reveals potential binding interfaces through differential solvent exposure
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - January 11, 2023 Category: Biomedical Science Authors: Saw Yen OwEugene A. KappVesna TomasetigAnton ZalewskiJason SimmondsCon PanousisMichael J. WilsonAndrew D. NashMatthias PelzingResearch and Development, CSL Limited, Bio21 Molecular Science and Biotechnology Institute, Parkville, Australia Source Type: research

Approaches to expand the conventional toolbox for discovery and selection of antibodies with drug-like physicochemical properties
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - January 11, 2023 Category: Biomedical Science Authors: Hristo L. Svilenov Paolo Arosio Tim Menzen Peter Tessier Pietro Sormanni Source Type: research

HDX-MS study on garadacimab binding to activated FXII reveals potential binding interfaces through differential solvent exposure
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - January 11, 2023 Category: Biomedical Science Authors: Saw Yen Ow Eugene A. Kapp Vesna Tomasetig Anton Zalewski Jason Simmonds Con Panousis Michael J. Wilson Andrew D. Nash Matthias Pelzing Source Type: research

Receptor occupancy assessment and interpretation in terms of quantitative systems pharmacology: nivolumab case study
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - December 16, 2022 Category: Biomedical Science Authors: Dmitry ShchelokovOleg Demin JrInSysBio UK Limited, Edinburgh, UK Source Type: research

Restoring the biological activity of crizanlizumab at physiological conditions through a pH-dependent aspartic acid isomerization reaction
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - December 15, 2022 Category: Biomedical Science Authors: Fabian BickelFran çois GriaudWolfram KernFrieder KroenerManuela GritschJérôme DayerSamuel BarteauBlandine DenefeldChi-Ya Kao-ScharfManuel LangIzabela Slupska-MuanzaCarla SchmidtMatthias BergJürgen SiggLina BoadoDirk CheliusAnalytical Development, Tech Source Type: research

Characterization of the high-affinity anti-CTLA-4 monoclonal antibody JS007 for immune checkpoint therapy of cancer
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - December 13, 2022 Category: Biomedical Science Authors: Jiawei GuanHongchuan LiuYan ChaiJie YuJian YaoJing WangZhiwei PanJing ZhangYuehua ZhouHui LiuSheng YaoJianxun QiHui FengGeorge F. GaoQihui WangYi ShiShuguang Tana Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Source Type: research

Developability profiling of a panel of Fc engineered SARS-CoV-2 neutralizing antibodies
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - December 8, 2022 Category: Biomedical Science Authors: Andrew DippelAustin GallegosVineela AletiArnita BarnesXiaoru ChenElizabeth ChristianJared DelmarQun DuReza EsfandiaryErika FarmerAndrew GarciaQing LiJia LinWeiyi LiuLeeAnn MachieskyNeil ModyArun ParupudiMeagan ProphetKeith RickertKim RosenthalSong RenHari Source Type: research