Mass spectrometry-based multi-attribute method in protein therapeutics product quality monitoring and quality control
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - April 14, 2023 Category: Biomedical Science Authors: Feng YangJennifer ZhangAlexander BuettnerEva VosikaMonica SadekZhiqi HaoDietmar ReuschMaximiliane KoenigWayman ChanAnja BathkeHilary PallatVictor LundinJochen Felix KepertPatrick BulauGalahad DeperaltaChristopher YuRichard BeardsleyTura CamilliReed Harris Source Type: research
Determination of ultra-trace metal-protein interactions in co-formulated monoclonal antibody drug product by SEC-ICP-MS
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - April 10, 2023 Category: Biomedical Science Authors: Laurence Whitty-L éveilléZachary L. VanAernumJorge Alexander PavonChrista MurphyKatie NealWilliam ForestXinliu GaoWendy ZhongDouglas D. RichardsonHillary A. SchuesslerAnalytical Research and Development, Merck & Co, Inc, Rahway, New Jersey Source Type: research
Trends in industrialization of biotherapeutics: a survey of product characteristics of 89 antibody-based biotherapeutics
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - March 31, 2023 Category: Biomedical Science Authors: Kyle P. MartinChristine GrimaldiRolf GremplerSteven HanselSandeep Kumara Biotherapeutics Discovery, Boehringer Ingelheim Pharmaceutical Inc, Ridgefield, CT, USAb Drug Metabolism and Pharmacokinetics, Boehringer Ingelheim Pharmaceutical Inc, Ridgefield, CT Source Type: research
Structure-based engineering of a novel CD3 ε-targeting antibody for reduced polyreactivity
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - March 30, 2023 Category: Biomedical Science Authors: Catherine Y LiuCory L AhonenMichael E BrownLing ZhouMartin WelinEric M KraulandRobert PejchalPaul F WidboomMichael B Battlesa Adimab, LLC, NH, USAb SARomics Biostructures AB, Lund, Sweden Source Type: research
Mechanistic PK/PD modeling to address early-stage biotherapeutic dosing feasibility questions
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - March 23, 2023 Category: Biomedical Science Authors: Joshuaine GrantFei HuaJoshua F. ApgarJohn M. BurkeDiana H. MarcantonioApplied BioMath, LLC, Concord, MA, USA Source Type: research
Impact of IgG subclass on monoclonal antibody developability
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - March 22, 2023 Category: Biomedical Science Authors: Paul CainLihua HuangYu TangVictor AnguianoYiqing Fenga Biotechnology Discovery Research, Lilly Research Laboratories, Lilly Technology Center North, Indianapolis, IN, USAb Bioproduct Research & Development, Lilly Research Laboratories, Lilly Technology C Source Type: research
Generation of robust bispecific antibodies through fusion of single-domain antibodies on IgG scaffolds: a comprehensive comparison of formats
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - March 20, 2023 Category: Biomedical Science Authors: Andreas V. MadsenPeter KristensenAlexander K. BuellSteffen Goletza Department of Biotechnology and Biomedicine, Technical University of Denmark, Kgs. Lyngby, Denmarkb Department of Chemistry and Bioscience, Aalborg University, Aalborg, Denmark Source Type: research
Blueprint for antibody biologics developability
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - March 7, 2023 Category: Biomedical Science Authors: Carl MieczkowskiXuejin ZhangDana LeeKhanh NguyenWei LvYanling WangYue ZhangJackie WayJean-Michel Griesa Department of Protein Sciences, Hengenix Biotech, Inc, Milpitas, CA, USAb President, Discovery Research, Hengenix Biotech, Inc, Milpitas, CA, USA Source Type: research
