Use of poxvirus display to select antibodies specific for complex membrane antigens
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - August 28, 2023 Category: Biomedical Science Authors: Ernest S. Smith Leslie A. Balch Maria Scrivens Shuying Shi Wei Wang Caroline D. Harvey Angelica A. Cornelison Malgorzata Gil-Moore Renee A. Kirk Loretta L. Mueller Richard L. Hall Alan P. Howell Christine A. Reilly Jessica M. Mayer Francis G. Murante Kari Source Type: research

Unique epitope –antibody interactions in the intrinsically disordered proteoglycan-like domain of human carbonic anhydrase IX defined by high-resolution NMR combined with yeast surface display
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - August 25, 2023 Category: Biomedical Science Authors: Feng NiCunle WuPing XuPing WangYves FortinMelanie ArbourLuke MassonDenis L ’AbbéAndrea AcelMylene GosselinAnne E.G. LenferinkHuman Health Therapeutics Research Centre, National Research Council Canada, Montreal, Quebec, Canada Source Type: research

A machine learning strategy for the identification of key in silico descriptors and prediction models for IgG monoclonal antibody developability properties
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - August 23, 2023 Category: Biomedical Science Authors: Andrew B. WaightDavid PrihodaRojan ShresthaKevin MetcalfMarc BaillyMarco AnconaTalal WidatallaZachary RollinsAlan C ChengDanny A. BittonLaurence Fayadat-Dilmana Discovery Biologics, Protein Sciences, Merck & Co., Inc, South San Francisco, CA, USAb Discov Source Type: research

Targeted chain-exchange-mediated reconstitution of a split type-I cytokine for conditional immunotherapy
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - August 23, 2023 Category: Biomedical Science Authors: Vedran VasicCan BuldunManfred RitzSteffen DickopfGuy J. GeorgesChristian SpickAlessa PeukerThomas MeierKlaus MayerUlrich Brinkmanna Roche Pharma Research and Early Development (pRED), Large Molecule Research, Roche Innovation Center Munich, Penzberg, Germ Source Type: research

A machine learning strategy for the identification of key in silico descriptors and prediction models for IgG monoclonal antibody developability properties
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - August 23, 2023 Category: Biomedical Science Authors: Andrew B. Waight David Prihoda Rojan Shrestha Kevin Metcalf Marc Bailly Marco Ancona Talal Widatalla Zachary Rollins Alan C Cheng Danny A. Bitton Laurence Fayadat-Dilman Source Type: research

Targeted chain-exchange-mediated reconstitution of a split type-I cytokine for conditional immunotherapy
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - August 23, 2023 Category: Biomedical Science Authors: Vedran Vasic Can Buldun Manfred Ritz Steffen Dickopf Guy J. Georges Christian Spick Alessa Peuker Thomas Meier Klaus Mayer Ulrich Brinkmann Source Type: research

Monte Carlo Thompson sampling-guided design for antibody engineering
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - August 22, 2023 Category: Biomedical Science Authors: Taro KakuzakiHikaru KogaShuuki TakizawaShoichi MetsugiHirotake ShiraiwaZenjiro SampeiKenji YoshidaHiroyuki TsunodaReiji TeramotoResearch Division, Chugai Pharmaceutical Co., Ltd., Yokohama, Japan Source Type: research

Selection of bispecific antibodies with optimal developability using FcRn ‑pH‑HPLC as an optimized FcRn affinity chromatography method
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - August 21, 2023 Category: Biomedical Science Authors: Thomas M üllerCarolin TasserMichael TesarIvica FucekUte Schniegler-MattoxJoachim KochKristina EllwangerDiscovery Research and Translational Immunology, Affimed GmbH, Heidelberg, Germany Source Type: research

Selection of bispecific antibodies with optimal developability using FcRn ‑Ph‑HPLC as an optimized FcRn affinity chromatography method
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - August 21, 2023 Category: Biomedical Science Authors: Thomas M üller Carolin Tasser Michael Tesar Ivica Fucek Ute Schniegler-Mattox Joachim Koch Kristina Ellwanger Source Type: research

Interplay of heavy chain introns influences efficient transcript splicing and affects product quality of recombinant biotherapeutic antibodies from CHO cells
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - August 9, 2023 Category: Biomedical Science Authors: Emma KelsallClaire HarrisTitash SenDiane HattonSarah DunnSuzanne GibsonCell Culture and Fermentation Sciences, Biopharmaceutical Development, R & D, AstraZeneca, Cambridge, UK Source Type: research

Advances in the structural characterization of complexes of therapeutic antibodies with PD-1 or PD-L1
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - August 2, 2023 Category: Biomedical Science Authors: Mengzhen JiangMan LiuGuodi LiuJiawen MaLixin ZhangShenlin WangState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China Source Type: research