Ultra ‐high performance liquid chromatography coupled to tandem mass spectrometry‐based metabolomics study of diabetic distal symmetric polyneuropathy
ConclusionsThe finding of the 12 signature metabolites might provide a novel perspective for the pathogenesis of DSPN. Future studies are required to test this observation further. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - June 23, 2023 Category: Endocrinology Authors: Jiahui Xu,
Qingguang Chen,
Mengjie Cai,
Xu Han,
Hao Lu Tags: ORIGINAL ARTICLE Source Type: research
Updates on dyslipidemia in patients with diabetes
(Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - June 22, 2023 Category: Endocrinology Authors: Shintaro Ide,
Yoshiro Maezawa,
Koutaro Yokote Tags: UPDATE Source Type: research
Issue Information
(Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - June 22, 2023 Category: Endocrinology Tags: Issue Information Source Type: research
The era of continuous glucose monitoring and its expanded role in type 2 diabetes
(Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - June 22, 2023 Category: Endocrinology Authors: Jin Yu,
Jae ‐Hyoung Cho,
Seung‐Hwan Lee Tags: UPDATE Source Type: research
Diet and exercise are a fundamental part of comprehensive care for type 2 diabetes
(Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - June 21, 2023 Category: Endocrinology Authors: Yun Kai Yeh,
Fu ‐Shun Yen,
Chii‐Min Hwu Tags: UPDATE Source Type: research
A case of fulminant type 1 diabetes and protein C deficiency complicated by deep vein thrombosis
We report a case of diabetic ketoacidosis (DKA) at the onset of fulminant type 1 diabetes, who developed massive deep vein thrombosis with pulmonary embolism after the acute-phase DKA treatment, it being subsequently recognized that he had type I protein C partial deficiency. Our case highlights that venous thrombosis should always be considered as a potential complication of DKA. AbstractA 25-year-old man was diagnosed with diabetic ketoacidosis (DKA) at the onset of fulminant type 1 diabetes. After acute-phase DKA treatment including placement of a central venous catheter, a massive deep vein thrombosis (DVT) and pulmona...
Source: Journal of Diabetes Investigation - June 16, 2023 Category: Endocrinology Authors: Masato Kohata,
Shinjiro Kodama,
Nobuhiro Yaoita,
Shinichiro Hosaka,
Kei Takahashi,
Keizo Kaneko,
Junta Imai,
Satoshi Yasuda,
Hideki Katagiri Tags: Case Report Source Type: research
Is a low ‐carbohydrate, high‐fat diet feasible for people with type 2 diabetes and nonalcoholic fatty liver disease?
More rigorous studies are needed to obtain robust and consistent results to provide helpful and feasible dietary recommendations for patients with type 2 diabetes and nonalcoholic fatty liver disease (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - June 15, 2023 Category: Endocrinology Authors: Fu ‐Shun Yen,
Pei‐Chuan Lee,
Chii‐Min Hwu Tags: COMMENTARY Source Type: research
LncRNA SNHG1 knockdown inhibits hyperglycemia induced ferroptosis via miR ‐16‐5p/ACSL4 axis to alleviate diabetic nephropathy
ConclusionsSNHG1 knockdown inhibited ferroptosisvia the miR-16-5p/ACSL4 axis to alleviate diabetic nephropathy, which provided some new insights for the novel treatment of diabetic nephropathy. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - June 14, 2023 Category: Endocrinology Authors: Xiangdong Fang,
Jianling Song,
Yanxia Chen,
Shuying Zhu,
Weiping Tu,
Ben Ke,
Lidong Wu Tags: Original Article Source Type: research
Predicting three categories of Dementia Assessment Sheet for Community ‐based Integrated Care System 8‐items score‐based glycemic targets using the number of animal names recalled
ConclusionsAnimal scores would be useful in predicting the categories of DASC-8. Animal fluency could be a screening tool of DASC-8 when a patient's family member or supportive person is absent. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - June 14, 2023 Category: Endocrinology Authors: Hiroko Hiiragi,
Taichi Minami,
Yasuo Terauchi Tags: Clinical Trial Source Type: research
A surge in serum mucosal cytokines associated with seroconversion in children at risk for type 1 diabetes
ConclusionsIn a cohort of children at risk for type 1 diabetes followed from birth, a transient, systemic increase in mucosa-associated cytokines around the time of seroconversion lends support to the view that mucosal infection, e.g., by an enteric virus, may drive the development of islet autoimmunity. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - June 14, 2023 Category: Endocrinology Authors: Leonard C Harrison,
Esther Bandala ‐Sanchez,
Helena Oakey,
Peter G Colman,
Kelly Watson,
Ki Wook Kim,
Roy Wu,
Emma E Hamilton‐Williams,
Natalie L Stone,
Aveni Haynes,
Rebecca L Thomson,
Peter J Vuillermin,
Georgia Soldatos,
William D Rawl Tags: Original Article Source Type: research
Long non ‐coding ribonucleic acid zinc finger E‐box binding homeobox 1 antisense RNA 1 regulates myocardial fibrosis in diabetes through the Hippo–Yes‐associated protein signaling pathway
ConclusionLong non-coding ribonucleic acid ZEB1-AS1 alleviated myocardial fibrosis through the miR-181c-5p –SIRT1–YAP axis in diabetic mice. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - June 13, 2023 Category: Endocrinology Authors: Jing Wu,
Rui Lyu,
Shumin Chen,
Xiaoguang Wang Tags: Original Article Source Type: research
Is caloric restriction enough to increase longevity? Fasting and circadian alignment
Effects of caloric restriction, fasting and circadian alignment on longevity in mice and potential risks and benefits of extrapolation to humans. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - June 12, 2023 Category: Endocrinology Authors: Yoshiyuki Hamamoto,
Takeshi Kurose,
Yutaka Seino Tags: Commentary Source Type: research
Blockade of glucagon increases muscle mass and alters fiber type composition in mice deficient in proglucagon ‐derived peptides
ConclusionsThese results show that hyperaminoacidemia induced by blockade of glucagon action in mice increases skeletal muscle weight and stimulates slow-to-fast transition in type II fibers of skeletal muscle, mimicking the phenotype of a high-protein diet. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - June 10, 2023 Category: Endocrinology Authors: Shinji Ueno,
Yusuke Seino,
Shihomi Hidaka,
Masashi Nakatani,
Keisuke Hitachi,
Naoya Murao,
Yasuhiro Maeda,
Haruki Fujisawa,
Megumi Shibata,
Takeshi Takayanagi,
Katsumi Iizuka,
Daisuke Yabe,
Yoshihisa Sugimura,
Kunihiro Tsuchida,
Yoshitaka Ha Tags: Original Article Source Type: research
Improving diagnostic accuracy of 3 Screen ICA ELISA kit in the identification of Japanese type 1 diabetes
ConclusionOur findings suggest that the 3 Screen ICA ELISA may be a valuable screening tool for Japanese patients with type 1 diabetes, potentially increasing the diagnostic sensitivity and accuracy beyond the existing GADA, IA-2A, and ZnT8A tests. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - June 9, 2023 Category: Endocrinology Authors: Eiji Kawasaki,
Hideaki Jinnouchi,
Yasutaka Maeda,
Akira Okada,
Yoshihisa Ito,
Koichi Kawai Tags: Original Article Source Type: research
Weight loss improves inflammation by T helper 17 cells in an obese patient with psoriasis at high risk for cardiovascular events
In this study, we found an increase in Th17 cells in a patient with obesity, type 2 diabetes and psoriasis. Furthermore, weight loss with diet and exercise resulted in a decrease in Th17 cells and improvement of psoriasis. This case supports the hypothesis that obesity leads to an increase in Th1 7 cells and chronic inflammation of the skin and blood vessel walls, thereby promoting psoriasis and atherosclerosis. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - June 9, 2023 Category: Endocrinology Authors: Yoshiro Maezawa,
Yusuke Endo,
Satomi Kono,
Tomohiro Ohno,
Yuumi Nakamura,
Naoya Teramoto,
Ayano Yamaguchi,
Kazuto Aono,
Takuya Minamizuka,
Hisaya Kato,
Takahiro Ishikawa,
Masaya Koshizaka,
Minoru Takemoto,
Toshinori Nakayama,
Koutaro Yokote Tags: CASE REPORT Source Type: research
