Issue Information
(Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - August 23, 2023 Category: Endocrinology Tags: Issue Information Source Type: research
Weight loss improves inflammation by T helper 17 cells in an obese patient with psoriasis at high risk for cardiovascular events
In this study, we found an increase in Th17 cells in a patient with obesity, type 2 diabetes and psoriasis. Furthermore, weight loss with diet and exercise resulted in a decrease in Th17 cells and improvement of psoriasis. This case supports the hypothesis that obesity leads to an increase in Th1 7 cells and chronic inflammation of the skin and blood vessel walls, thereby promoting psoriasis and atherosclerosis. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - August 23, 2023 Category: Endocrinology Authors: Yoshiro Maezawa,
Yusuke Endo,
Satomi Kono,
Tomohiro Ohno,
Yuumi Nakamura,
Naoya Teramoto,
Ayano Yamaguchi,
Kazuto Aono,
Takuya Minamizuka,
Hisaya Kato,
Takahiro Ishikawa,
Masaya Koshizaka,
Minoru Takemoto,
Toshinori Nakayama,
Koutaro Yokote Tags: Case Report Source Type: research
Machine learning for the prediction of atherosclerotic cardiovascular disease during 3 ‐year follow up in Chinese type 2 diabetes mellitus patients
ConclusionsThe prediction models offer opportunities to personalize treatment and maximize the benefits of these medical interventions. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - August 23, 2023 Category: Endocrinology Authors: Jinru Ding,
Yingying Luo,
Huwei Shi,
Ruiyao Chen,
Shuqing Luo,
Xu Yang,
Zhongzhou Xiao,
Bilin Liang,
Qiujuan Yan,
Jie Xu,
Linong Ji Tags: Original Article Source Type: research
Incretin hormone responses to carbohydrate and protein/fat are preserved in adults with sulfonylurea ‐treated KCNJ11 neonatal diabetes
Insulin secretion in individuals with sulfonylurea-treatedKCNJ11 permanent neonatal diabetes is thought to be dependent on non- adenosine triphosphate-sensitive potassium channel pathways; for example, incretin hormones. We assessed incretin hormone secretion after different foods in individuals with sulfonylurea-treatedKCNJ11 permanent neonatal diabetes, in comparison with people without diabetes. Patterns of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 secretion after protein/fat and carbohydrate meals were similar in cases and controls. An intact incretin pathway might provide a therapeutic t...
Source: Journal of Diabetes Investigation - August 22, 2023 Category: Endocrinology Authors: Pamela Bowman,
Kashyap A Patel,
Timothy J McDonald,
Jens J Holst,
Bolette Hartmann,
Maria Leveridge,
Beverley M Shields,
Suzie Hammersley,
Steve R Spaull,
Bridget A Knight,
Sarah E Flanagan,
Maggie H Shepherd,
Rob C Andrews,
Andrew T Hattersl Tags: Short Report Source Type: research
Factors associated with bleeding complications in patients with coronavirus disease 2019 admitted to intensive care units: A multicenter retrospective cohort study
ConclusionsIn patients with severe COVID-19 with high glycated hemoglobin and renal failure, we recommend additional attention to the course of COVID-19, given the risk of bleeding complications. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - August 16, 2023 Category: Endocrinology Authors: Dan Imai,
Emi Ushigome,
Masahide Hamaguchi,
Satoru Hashimoto,
Michiaki Fukui Tags: Original Article Source Type: research
Elevated serum uric acid is a risk factor for progression to prediabetes in Japanese women: A 5 ‐year retrospective chort study
ConclusionsThe results indicate that elevated serum SUA levels might be positively and independently associated with an increased risk of progression to prediabetes in Japanese women. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - August 9, 2023 Category: Endocrinology Authors: Masanori Shimodaira,
Yu Minemura,
Tomohiro Nakayama Tags: Original Article Source Type: research
Sarcopenia: Loss of mighty armor against frailty and aging
The goal of diabetes management is to achieve longevity and quality of life equivalent to those of people without diabetes, and for that, it is now deemed important to pay close attention not only to diabetic vascular complications but also to diabetic comorbidities, as is recommended by the Japan Diabetes Society. In this editorial, we focus on sarcopenia as an important diabetic comorbidity which is an aging-related phenomenon in skeletal muscle. Taking our recent report on a sarcopenia mouse model and other accumulated evidence into account, we propose the existence of a skeletal muscle-centered inter-tissue network tha...
Source: Journal of Diabetes Investigation - August 8, 2023 Category: Endocrinology Authors: Takayoshi Sasako,
Kohjiro Ueki Tags: Editorial Source Type: research
Association between hemoglobin glycation index and non ‐alcoholic fatty liver disease in the patients with type 2 diabetes mellitus
ConclusionsA higher HGI suggests an elevated risk of developing NAFLD in patients with type 2 diabetes. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - August 8, 2023 Category: Endocrinology Authors: Meng Wang,
Shiwei Li,
Xinxin Zhang,
Xin Li,
Jingqiu Cui Tags: Original Article Source Type: research
Diabetic ketoacidosis due to a sensor defect of FreeStyle Libre: A case report
We report a case of a 59-year-old man with type 1 diabetes mellitus who developed diabetic ketoacidosis due to a sensor defect. After replacing the sensor with a new one, the glucose value shown in the device was much lower than usual, which made him consider that he was hypoglycemic. Accordingly, he reduced his insulin dose and eventually developed diabetic ketoacidosis. He was unaware of the discrepancy due to the lack of self-monitoring of his blood glucose, although he was educated to do. In sum, glucose monitoring with the FreeStyle Libre is helpful; however, it is necessary to remind the patient that a sensor defect ...
Source: Journal of Diabetes Investigation - August 3, 2023 Category: Endocrinology Authors: Toshiki Kogai,
Junko Sato,
Marin Hirakata,
Tatsuya Iwamoto,
Kenichi Nakajima,
Hiromasa Goto,
Yuya Nishida,
Hirotaka Watada Tags: CASE REPORT Source Type: research
Real ‐world risk of cardiovascular diseases in patients with type 2 diabetes associated with sodium–glucose cotransporter 2 inhibitors in comparison with metformin: A propensity score‐matched model analysis in Japan
Risk of CVD using SGLT2Is compared with metformin. AbstractWe aimed to compare the effects of cardiovascular disease risk in Japanese patients with type 2 diabetes on sodium–glucose cotransporter 2 inhibitors (SGLT2Is) or metformin. This retrospective, real-world cohort study was carried out using a claims database and propensity score matching; 58,402 eligible patients (29,201 per group) were included. The outcomes included nonfatal myocardi al infarction, angina pectoris, nonfatal stroke, hospitalization for heart failure and composite end-points. The hazard ratio (HR) for the composite end-point was 0.79, which w...
Source: Journal of Diabetes Investigation - July 31, 2023 Category: Endocrinology Authors: Takeshi Horii,
Yoichi Oikawa,
Akira Shimada,
Kiyoshi Mihara Tags: SHORT REPORT Source Type: research
Prediabetes and the risk of lung cancer incidence and mortality: A meta ‐analysis
ConclusionsPrediabetes might be associated with a mildly increased risk of lung cancer incidence in men, but not in women. In addition, prediabetes may be related to a higher risk of lung cancer mortality in the adult population. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - July 30, 2023 Category: Endocrinology Authors: Enjian Shen,
Xi Chen Tags: Original Article Source Type: research
Associations of polyneuropathy with risk of all ‐cause and cardiovascular mortality, cardiovascular disease events stratified by diabetes status
ConclusionsPolyneuropathy was associated with all-cause and cardiovascular mortality, and with CVD events in subjects with diabetes or prediabetes, even those having normal glucose tolerance. This study suggests the importance of polyneuropathy as a risk factor for death and highlights the necessity of early diagnosis and lifestyle intervention for those with type 2 diabetes and polyneuropathy. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - July 30, 2023 Category: Endocrinology Authors: Kyuho Kim,
Su ‐Nam Lee,
Yu‐Bae Ahn,
Seung‐Hyun Ko,
Jae‐Seung Yun Tags: Original Article Source Type: research
Delineating the transcriptional atlas for impaired insulin secretion: A window into type 2 diabetes pathophysiology
(Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - July 27, 2023 Category: Endocrinology Authors: Jian Li,
Jin Yang,
Tianpei Hong Tags: COMMENTARY Source Type: research
Successful introduction of sensor ‐augmented pump therapy in a patient with diabetes and needle phobia: A case report
We reported a successful introduction of SAP in an adult with pancreatic diabetes and needle phobia. The SAP treatment achieved self-management, better glycemic control, and high treatment satisfaction quantified using the Diabetes Treatment Satisfaction Questionnaire. Our case demonstrates that SAP is a potentially effective therapy in adults with needle phobia and diabetes requiring insulin therapy. ABSTRACTNeedle phobia is a specific phobia classified as an anxiety disorder in the Diagnostic and Statistical Manual of Mental Disorders-5, and can be a serious problem for patients requiring insulin injections. However, the...
Source: Journal of Diabetes Investigation - July 26, 2023 Category: Endocrinology Authors: Keiji Sugai,
Junpei Shikuma,
Satoshi Hiroike,
Hironori Abe,
Ryo Suzuki Tags: Case Report Source Type: research
Polar vasculosis is associated with better kidney outcome in type 2 diabetes with biopsy ‐proven diabetic kidney disease: A multicenter cohort study
ConclusionsThis study showed that polar vasculosis of DKD was associated with less advanced IFTA and a better kidney outcome in type 2 diabetes with proteinuria. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - July 23, 2023 Category: Endocrinology Authors: Miho Shimizu,
Kengo Furuichi,
Tadashi Toyama,
Masayuki Yamanouchi,
Junichi Hoshino,
Shinji Kitajima,
Akinori Hara,
Yasunori Iwata,
Norihiko Sakai,
Yukio Yuzawa,
Hiroshi Kitamura,
Hiroshi Sato,
Yugo Shibagaki,
Yoshiki Suzuki,
Noriko Uesugi,
Tags: Original Article Source Type: research
