Issue Information
(Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - September 21, 2023 Category: Endocrinology Tags: Issue Information Source Type: research
Non ‐classical monocytes frequency and serum vitamin D3 levels are linked to diabetic foot ulcer associated with peripheral artery disease
ConclusionsNon-classical monocytes frequency and vitamin D3 levels were significantly reduced in DFU patients with PAD. Non-classical monocytes frequency was associated with vitamin D3 in DFUs patients, and both parameters were linked to lipid profile. Vitamin D3 upregulation was a risk-reducing factor for PAD occurrence. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - September 21, 2023 Category: Endocrinology Authors: Reham Hammad,
Maisa A Abdel Wahab,
Nehal Farouk,
Mohamed Yahia Zakaria,
Mona A Eldosoky,
Asmaa A Elmadbouly,
Sara A Tahoun,
Eman Mahmoud,
Seham K Khirala,
Amena Rezk Mohammed,
Wafaa Abdelaziz Emam,
Asmaa A Abo Elqasem,
Fatma M Kotb,
Rasha Abd Tags: ORIGINAL ARTICLE Source Type: research
Imeglimin ‐mediated glycemic control in maternally inherited deafness and diabetes
We studied the effect of imeglimin in a patient with maternally inherited diabetes and deafness (MIDD). Imeglimin potentially improves glucose concentration-dependent insulin secretion and metabolism in MIDD. Imeglimin shows potential as a new treatment for MIDD. AbstractMitochondrial dysfunction causes maternally inherited deafness and diabetes (MIDD). Herein, we report improved glycemic control in a 47-year-old Japanese woman with MIDD using imeglimin without major adverse effects. Biochemical tests and metabolome analysis were performed before and after imeglimin administration. Blood glucose level fluctuations were det...
Source: Journal of Diabetes Investigation - September 16, 2023 Category: Endocrinology Authors: Ryoichi Ishibashi,
Kiichi Hirayama,
Suzuka Watanabe,
Kosuke Okano,
Yuta Kuroda,
Yusuke Baba,
Takuma Kanayama,
Chiho Ito,
Keisuke Kasahara,
Saki Aiba,
Ryo Iga,
Ryohei Ohtani,
Yosuke Inaba,
Masaya Koshizaka,
Yoshiro Maezawa,
Koutaro Yokote Tags: Case Report Source Type: research
Advantages of sensor ‐augmented insulin pump therapy for pregnant women with type 1 diabetes mellitus
ConclusionThe present study showed that SAP therapy is more effective in preventing large for gestational age newborns in pregnant women with type 1 diabetes mellitus than CSII/SMBG. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - September 15, 2023 Category: Endocrinology Authors: Hitomi Imafuku,
Kenji Tanimura,
Naohisa Masuko,
Masako Tomimoto,
Yutoku Shi,
Akiko Uchida,
Masashi Deguchi,
Kazumichi Fujioka,
Akane Yamamoto,
Kei Yoshino,
Yushi Hirota,
Wataru Ogawa,
Yoshito Terai Tags: Original Article Source Type: research
Type 1 diabetes, COVID‐19 vaccines and short‐term safety: Subgroup analysis from the global COVAD study
ConclusionsCOVID-19 vaccination was safe and well tolerated in patients with type 1 diabetes with similar AE profiles compared with HCs, although severe rashes were more common in type 1 diabetes patients. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - September 12, 2023 Category: Endocrinology Authors: Tulika Chatterjee,
Naveen Ravichandran,
Narmadha Nair,
Abraham Edgar Gracia ‐Ramos,
Bhupen Barman,
Parikshit Sen,
Mrudula Joshi,
Sreoshy Saha,
Arvind Nune,
Arun Kumar R Pande,
Tsvetelina Velikova,
Ioannis Parodis,
Ai Lyn Tan,
Samuel Katsuyu Tags: Original Article Source Type: research
Local low ‐frequency vibration accelerates healing of full‐thickness wounds in a hyperglycemic rat model
ConclusionsThe results suggest that LLFV promotes wound healing, improves glycometabolism and inflammation, and enhances vasodilation and angiogenesis in hyperglycemic wounds. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - September 9, 2023 Category: Endocrinology Authors: Daijiro Haba,
Qi Qin,
Chihiro Takizawa,
Sanai Tomida,
Takeo Minematsu,
Hiromi Sanada,
Gojiro Nakagami Tags: Original Article Source Type: research
Exosomal circHIPK3 derived from umbilical cord ‐derived mesenchymal stem cells enhances skin fibroblast autophagy by blocking miR‐20b‐5p/ULK1/Atg13 axis
ConclusionUCMSCs-derived exosomal circHIPK3 promoted cell autophagy and proliferation and accelerated the fibroblast injury repair by the miR-20b-5p/ULK1/Atg13 axis. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - September 9, 2023 Category: Endocrinology Authors: Zhi ‐Yang Qiu,
Shi‐Shuai Lin,
Nan‐Fang Pan,
Zhi‐Hu Lin,
Yun‐Chuan Pan,
Zun‐Hong Liang Tags: Original Article Source Type: research
Prospective randomized comparative study of the effect of pemafibrate add ‐on or double statin dose on small dense low‐density lipoprotein‐cholesterol in patients with type 2 diabetes and hypertriglyceridemia on statin therapy
ConclusionsIn patients with type 2 diabetes and hypertriglyceridemia, the addition of pemafibrate to a statin is superior to doubling a statin in reducing sdLDL-C without increasing adverse effects. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - August 31, 2023 Category: Endocrinology Authors: Tsutomu Hirano,
Toshiyuki Hayashi,
Hiroe Sugita,
Atsuko Tamasawa,
Satoshi Goto,
Masako Tomoyasu,
Takeshi Yamamoto,
Makoto Ohara,
Michishige Terasaki,
Hideki Kushima,
Yasuki Ito,
Sho ‐ichi Yamagishi,
Yusaku Mori Tags: CLINICAL TRIAL Source Type: research
Glycated hemoglobin variability and the risk of cardiovascular events in patients with prediabetes and type 2 diabetes mellitus: A post‐hoc analysis of a prospective and multicenter study
ConclusionHigh HbA1c variability in the highest quartile showed a statistically significant association with multiple adverse cardiovascular events in an Asian population. Minimizing HbA1c fluctuation during long-term follow up should be another important objective for type 2 diabetes patients. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - August 24, 2023 Category: Endocrinology Authors: Worapaka Manosroi,
Mattabhorn Phimphilai,
Nipawan Waisayanand,
Supawan Buranapin,
Chaicharn Deerochanawong,
Siriluck Gunaparn,
Arintaya Phrommintikul,
Wanwarang Wongcharoen,
for the CORE ‐Thailand investigators Tags: Original Article Source Type: research
Baseline prevalence of hyperglycemia and its predictors among community clinic users of a selected rural area of Bangladesh: A cross ‐sectional study using the WHO PEN Protocol 1
ConclusionsHyperglycemia, preD and type 2 diabetes showed a comparatively high prevalence among the CC users of the selected rural area. Obesity and hypertension are the key modifiable risk factors that should be reduced using a CC-centered risk reduction strategy. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - August 23, 2023 Category: Endocrinology Authors: Mithila Faruque,
Lingkan Barua,
Shagoofa Rakhshanda,
Palash Chandra Banik,
Riffat Ara Shawon,
AKM Fazlur Rahman,
Saidur Rahman Mashreky Tags: Original Article Source Type: research
Efficacy, safety and tolerability of imeglimin in patients with type 2 diabetes mellitus: A meta‐analysis of randomized controlled trials
ConclusionsImeglimin is efficacious, safe, and well tolerated as monotherapy and adjunctive therapy. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - August 23, 2023 Category: Endocrinology Authors: Katsuhiko Hagi,
Masahiro Nitta,
Hirotaka Watada,
Kohei Kaku,
Kohjiro Ueki Tags: ORIGINAL ARTICLE Source Type: research
Issue Information
(Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - August 23, 2023 Category: Endocrinology Tags: Issue Information Source Type: research
Weight loss improves inflammation by T helper 17 cells in an obese patient with psoriasis at high risk for cardiovascular events
In this study, we found an increase in Th17 cells in a patient with obesity, type 2 diabetes and psoriasis. Furthermore, weight loss with diet and exercise resulted in a decrease in Th17 cells and improvement of psoriasis. This case supports the hypothesis that obesity leads to an increase in Th1 7 cells and chronic inflammation of the skin and blood vessel walls, thereby promoting psoriasis and atherosclerosis. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - August 23, 2023 Category: Endocrinology Authors: Yoshiro Maezawa,
Yusuke Endo,
Satomi Kono,
Tomohiro Ohno,
Yuumi Nakamura,
Naoya Teramoto,
Ayano Yamaguchi,
Kazuto Aono,
Takuya Minamizuka,
Hisaya Kato,
Takahiro Ishikawa,
Masaya Koshizaka,
Minoru Takemoto,
Toshinori Nakayama,
Koutaro Yokote Tags: Case Report Source Type: research
Machine learning for the prediction of atherosclerotic cardiovascular disease during 3 ‐year follow up in Chinese type 2 diabetes mellitus patients
ConclusionsThe prediction models offer opportunities to personalize treatment and maximize the benefits of these medical interventions. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - August 23, 2023 Category: Endocrinology Authors: Jinru Ding,
Yingying Luo,
Huwei Shi,
Ruiyao Chen,
Shuqing Luo,
Xu Yang,
Zhongzhou Xiao,
Bilin Liang,
Qiujuan Yan,
Jie Xu,
Linong Ji Tags: Original Article Source Type: research
Incretin hormone responses to carbohydrate and protein/fat are preserved in adults with sulfonylurea ‐treated KCNJ11 neonatal diabetes
Insulin secretion in individuals with sulfonylurea-treatedKCNJ11 permanent neonatal diabetes is thought to be dependent on non- adenosine triphosphate-sensitive potassium channel pathways; for example, incretin hormones. We assessed incretin hormone secretion after different foods in individuals with sulfonylurea-treatedKCNJ11 permanent neonatal diabetes, in comparison with people without diabetes. Patterns of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 secretion after protein/fat and carbohydrate meals were similar in cases and controls. An intact incretin pathway might provide a therapeutic t...
Source: Journal of Diabetes Investigation - August 22, 2023 Category: Endocrinology Authors: Pamela Bowman,
Kashyap A Patel,
Timothy J McDonald,
Jens J Holst,
Bolette Hartmann,
Maria Leveridge,
Beverley M Shields,
Suzie Hammersley,
Steve R Spaull,
Bridget A Knight,
Sarah E Flanagan,
Maggie H Shepherd,
Rob C Andrews,
Andrew T Hattersl Tags: Short Report Source Type: research
