Association between glycemia risk index and arterial stiffness in type 2 diabetes
ConclusionGlycemia risk index assessed by continuous glucose monitoring is associated with increased arterial stiffness in type 2 diabetes. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - January 22, 2024 Category: Endocrinology Authors: Lingli Cai,
Wenqi Shen,
Jiang Li,
Bin Wang,
Ying Sun,
Yi Chen,
Ling Gao,
Fei Xu,
Xinhua Xiao,
Ningjian Wang,
Yingli Lu Tags: Original Article Source Type: research
Epac2 activation mediates glucagon ‐induced glucogenesis in primary rat hepatocytes
ConclusionsEpac signaling plays a role in mediating the glucogenic action of glucagon in the hepatocytes. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - January 20, 2024 Category: Endocrinology Authors: Yusuke Shiozaki ‐Takagi,
Nobuaki Ozaki,
Yukiyasu Toyoda Tags: Original Article Source Type: research
Deciphering the causal tapestry between cardiorespiratory fitness and type 2 diabetes mellitus
(Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - January 20, 2024 Category: Endocrinology Authors: Fu ‐Shun Ko,
Yun‐Kai Yeh,
Fu‐Shun Yen,
Chii‐Min Hwu Tags: Commentary Source Type: research
Development and validation of a prediction model for self ‐reported hypoglycemia risk in patients with type 2 diabetes: A longitudinal cohort study
ConclusionsThe study developed 3 and 6 month hypoglycemia risk prediction models for patients with type 2 diabetes. The discrimination and calibration of the two prediction models were good, and might help to improve clinical decision-making and guide patients to more reasonable self-care and hypoglycemia prevention at home. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - January 20, 2024 Category: Endocrinology Authors: Hongmei Xu,
Hangqing Yu,
Zhengnan Cheng,
Chun Mu,
Di Bao,
Xiaohui Li,
Qiuling Xing Tags: Original Article Source Type: research
Microvascular permeability and texture analysis of bone marrow in diabetic rabbits with critical limb ischemia based on dynamic contrast ‐enhanced magnetic resonance imaging
ConclusionsThe early stages of diabetic bone marrow with CLI can be evaluated by DCE-MRI for microvascular permeability. Texture analysis based on DCE-MRI could act as an imaging discriminator and new radiological analysis tool for critical limb ischemia in diabetes mellitus. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - January 19, 2024 Category: Endocrinology Authors: Liu Yang,
Donghang Li,
Yuchen Yan,
Qi Yang,
Liang Li,
Yunfei Zha Tags: Original Article Source Type: research
Prevalence and characteristics of diabetic symmetric sensorimotor polyneuropathy in Japanese patients with type 2 diabetes: The Japan Diabetes Complication and its Prevention Prospective study (JDCP study 10)
This study aimed to investigate the prevalence and characteristics of diabetic symmetric sensorimotor polyneuropathy (DSPN) in patients with type 2 diabetes registered in the Japan Diabetes Complication and its Prevention Prospective study. In the study, 6,338 patients with diabetes who had been treated by diabetes specialists were registered in 2007–2009. Of these, patients with type 2 diabetes who could be evaluated for DSPN were ana lyzed using thet-test, χ2-test and logistic regression analyses. DSPN was diagnosed using the Simple Diagnostic Criteria for Diabetic Polyneuropathy proposed by the Diabetic Neuropat...
Source: Journal of Diabetes Investigation - January 12, 2024 Category: Endocrinology Authors: Hideki Kamiya,
Tatsuhito Himeno,
Atsuko Watarai,
Masayuki Baba,
Rimei Nishimura,
Naoko Tajima,
Jiro Nakamura Tags: Special Research Report Source Type: research
Overnutrition in the early postnatal period influences lifetime metabolic risk: Evidence for impact on pancreatic β‐cell mass and function
Diabetes causes substantial morbidity and mortality worldwide, as well as high societal cost. Risk of metabolic disease in adulthood increases in people with accelerated childhood growth trajectory. This review explores the metabolic impact of postnatal overnutrition in humans and in rodent models, with specific attention to the connection between accelerated childhood growth and future adiposity, insulin resistance, β-cell mass and β-cell dysfunction. AbstractOverconsumption of energy-rich foods that disrupt caloric balance is a fundamental cause of overweight, obesity and diabetes. Dysglycemia and the resulting cardiov...
Source: Journal of Diabetes Investigation - January 10, 2024 Category: Endocrinology Authors: Joshua JN Burton,
Laura C Alonso Tags: Review Source Type: research
Advancements and challenges in pancreatic islet transplantation: Insights from the Collaborative Islet Transplant Registry
(Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - January 9, 2024 Category: Endocrinology Authors: Eun Young Lee,
Kun ‐Ho Yoon Tags: Commentary Source Type: research
Resistant starch and type 2 diabetes mellitus: Clinical perspective
Starch is a significant source of carbohydrates and resistant starch, which is a non-viscous fermentable fiber, has shown to enhance glucose metabolism. The efficacy of resistant starch as a medical nutrition therapy for type 2 diabetes needs further investigation. AbstractThe immediate and well-documented benefits of carbohydrate restriction include improved glycemic control in individuals with diabetes mellitus. Starch, a significant source of carbohydrates, is categorized as rapidly digestible, slowly digestible, or resistant starch (RS). RS, which is a non-viscous fermentable fiber, has shown promise in animal studies ...
Source: Journal of Diabetes Investigation - January 8, 2024 Category: Endocrinology Authors: Min Kyung Kim,
Juri Park,
Doo ‐Man Kim Tags: Review Source Type: research
New diagnostic criteria (2023) for slowly progressive type 1 diabetes (SPIDDM): Report from Committee on Type 1 Diabetes of the Japan Diabetes Society (English version)
The diagnostic criteria for slowly progressive type 1 diabetes (slowly progressive insulin-dependent diabetes mellitus; SPIDDM) have been revised by the Committee on Type 1 Diabetes of the Japan Diabetes Society. AbstractThe diagnostic criteria for slowly progressive type 1 diabetes (slowly progressive insulin-dependent diabetes mellitus; SPIDDM) have been revised by the Committee on Type 1 Diabetes of the Japan Diabetes Society. All of the following three criteria must be met for ‘a definitive diagnosis of SPIDDM’: (1) presence of anti-islet autoantibodies at some point in time during the disease course; (2) absence o...
Source: Journal of Diabetes Investigation - January 8, 2024 Category: Endocrinology Authors: Akira Shimada,
Eiji Kawasaki,
Norio Abiru,
Takuya Awata,
Yoichi Oikawa,
Haruhiko Osawa,
Hiroshi Kajio,
Junji Kozawa,
Kazuma Takahashi,
Daisuke Chujo,
Shinsuke Noso,
Tomoyasu Fukui,
Junnosuke Miura,
Kazuki Yasuda,
Hisafumi Yasuda,
Akihisa Im Tags: Special Research Report Source Type: research
Prognostic value of longitudinal HbA1c variability in predicting the development of diabetic sensorimotor polyneuropathy among patients with type 2 diabetes mellitus: A prospective cohort observational study
ConclusionsApart from age and diabetes duration, HbA1c variability emerged as a robust predictor for the occurrence of new DSPN. Among the various measures of HbA1c variability evaluated, HbA1c ARV demonstrated the highest potential as a reliable indicator for anticipating the onset of new DSPN. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - January 3, 2024 Category: Endocrinology Authors: Yun ‐Ru Lai,
Wen‐Chan Chiu,
Chih‐Cheng Huang,
Ben‐Chung Cheng,
I‐Hsun Yu,
Chia‐Te Kung,
Ting Yin Lin,
Hui Ching Chiang,
Chun‐En Aurea Kuo,
Cheng‐Hsien Lu Tags: Original Article Source Type: research
Issue Information
(Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - January 2, 2024 Category: Endocrinology Tags: Issue Information Source Type: research
Identification of eight genomic protective alleles for mitochondrial diabetes by Kinship ‐graph convolutional network
ConclusionsThere are protective alleles in the nuclear genome that are associated with the onset-age of MIDD patients and might also provide protective effects on the deafness derived from MIDD patients. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - December 30, 2023 Category: Endocrinology Authors: Jiahao Wang,
Dandan Yan,
Haoyue Cui,
Rong Zhang,
Xiaojing Ma,
Luonan Chen,
Cheng Hu,
Jiarui Wu Tags: Original Article Source Type: research
Short ‐term recovery of insulin secretion in response to a meal is associated with future glycemic control in type 2 diabetes patients
ConclusionsShort-term recovery of insulin secretion in response to a meal during hospitalization, evaluated with the index-C, might predict future glycemic control. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - December 28, 2023 Category: Endocrinology Authors: Asako Enkaku,
Daisuke Chujo,
Miki Kamigishi,
Shinya Inagawa,
Shinnosuke Matsukoshi,
Waka Sakai,
Akiko Takikawa,
Shiho Fujisaka,
Kazuyuki Tobe Tags: Original Article Source Type: research
Comparative effects of fixed ‐dose mitiglinide/voglibose combination and glimepiride on vascular endothelial function and glycemic variability in patients with type 2 diabetes: A randomized controlled trial
ConclusionsIn our short-duration randomized crossover study, although not impacting vascular endothelial function, mitiglinide/voglibose demonstrated potential benefits in reducing glycemic variability, postprandial hyperglycemia, and hypoglycemia in patients with type 2 diabetes. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - December 27, 2023 Category: Endocrinology Authors: Kenichi Tanaka,
Yosuke Okada,
Saeko Umezu,
Ryoma Hashimoto,
Yukiko Tomoyose,
Rina Tateyama,
Yuri Hori,
Momo Saito,
Akemi Tokutsu,
Satomi Sonoda,
Fumi Uemura,
Akira Kurozumi,
Yoshiya Tanaka Tags: Clinical Trial Source Type: research
