A surge in serum mucosal cytokines associated with seroconversion in children at risk for type 1 diabetes

ConclusionsIn a cohort of children at risk for type 1 diabetes followed from birth, a transient, systemic increase in mucosa-associated cytokines around the time of seroconversion lends support to the view that mucosal infection, e.g., by an enteric virus, may drive the development of islet autoimmunity.

Source: Journal of Diabetes Investigation - June 14, 2023 Category: Endocrinology Authors: Leonard C Harrison, Esther Bandala ‐Sanchez, Helena Oakey, Peter G Colman, Kelly Watson, Ki Wook Kim, Roy Wu, Emma E Hamilton‐Williams, Natalie L Stone, Aveni Haynes, Rebecca L Thomson, Peter J Vuillermin, Georgia Soldatos, William D Rawl Tags: Original Article Source Type: research