Corneal Cross-Linking: The Science Beyond the Myths and Misconceptions
Conclusions: Improved understanding of the complex interactions of riboflavin, ultraviolet A energy and oxygen in corneal CXL may provide a successful route to transepithelial corneal CXL. (Source: Cornea)
Source: Cornea - May 15, 2019 Category: Opthalmology Tags: Review Source Type: research

Fibrin Glue–Assisted Closure of Macroperforation in Predescemetic Deep Anterior Lamellar Keratoplasty With a Donor Obtained From Small Incision Lenticule Extraction
Conclusions: A donor lenticule from SMILE surgery is a useful adjunct to seal macroperforations in deep anterior lamellar keratoplasty because the thin uniform lamellar tissue is easily applied using fibrin glue and gives uniform and good apposition on both host and donor sides. It can be used immediately without further preparation unlike hand-fashioned patch grafts. (Source: Cornea)
Source: Cornea - May 15, 2019 Category: Opthalmology Tags: Techniques Source Type: research

Management of Descemet Membrane's Folds After Deep Anterior Lamellar Keratoplasty: Descemet Membrane—Tucking Technique
Conclusions: DALK is the procedure of choice for the surgical treatment of corneal stromal diseases with a healthy endothelium, such as keratoconus. DM folds are a possible complication after DALK in patients with advanced corneal ectasia, arising from the compression of the redundant host DM by the donor graft, once it is sutured to the recipient. DM folds after DALK, when they involve the visual axis, cause permanent visual disturbances DM tucking allows the displacement of the central DM folds toward the graft margin, where they do not affect the patient's quality of vision. (Source: Cornea)
Source: Cornea - May 15, 2019 Category: Opthalmology Tags: Techniques Source Type: research

Double-Line Reflection Pattern as a Simple Method to Determine Graft Orientation of Descemet Membrane Endothelial Keratoplasty
Conclusions: This method of confirming correct graft orientation requires no additional procedures, equipment, or manipulation of the donor tissue and can be used in conjunction with other marking methods already described. (Source: Cornea)
Source: Cornea - May 15, 2019 Category: Opthalmology Tags: Techniques Source Type: research

Corneal Biofilm Plaques: A Novel Clinical Presentation
Conclusions: Corneal plaques are a very rare clinical presentation of corneal biofilms that allow prolonged survival of microorganisms even in the absence of prosthetic material and clinical signs or symptoms of corneal active inflammation and/or infection. (Source: Cornea)
Source: Cornea - May 15, 2019 Category: Opthalmology Tags: Case Report Source Type: research

Descemet Membrane Endothelial Keratoplasty Using Tissues From Donors With a History of Radial Keratotomy
Conclusions: Two patients received successful DMEK grafts using tissues from donors with a history of RK. Careful eye bank screening and processing of RK donor tissues has thus far yielded similar outcomes in our recipient patients to what would be expected using tissues from donors without a history of RK. (Source: Cornea)
Source: Cornea - May 15, 2019 Category: Opthalmology Tags: Case Report Source Type: research

Coincidental Occurrence of Schnyder Corneal Dystrophy and Posterior Polymorphous Corneal Dystrophy Type 3
Conclusions: This case illustrates the coincidental occurrence of 2 rare and genetically distinct corneal dystrophies in a single patient. Furthermore, it highlights the need to perform comprehensive phenotyping in combination with appropriate genetic diagnostic testing to achieve an accurate diagnosis. (Source: Cornea)
Source: Cornea - May 15, 2019 Category: Opthalmology Tags: Case Report Source Type: research

Optical Coherence Tomography Assessment of the Cornea During Corneal Swelling: Should the Term “Descemet Membrane Folds” Be Reconsidered?
Conclusions: Folds in DM associated with corneal edema originate in the middle and posterior stroma and are secondarily transmitted into DM. On the basis of the stromal origin of these anatomic changes, “stromal folds” should be considered a more accurate term to replace “Descemet membrane folds.” (Source: Cornea)
Source: Cornea - May 15, 2019 Category: Opthalmology Tags: Basic Investigation Source Type: research

Peripheral Endothelial Cell Density in Descemet Membrane Endothelial Keratoplasty Grafts
Purpose: To compare the variation in corneal endothelial cell density (ECD) from the center to the periphery in unpeeled and peeled donor corneas and to determine the impact of eccentric trephining on total endothelial cells in Descemet membrane endothelial keratoplasty (DMEK) grafts. Methods: Mated donor cornea pairs were obtained. One cornea from each pair was peeled for DMEK, whereas the other was left unpeeled. Alizarin Red was used to stain the endothelial cells. High-resolution images at fixed magnification were obtained for the center, midperiphery (2.5 mm from the center), and the periphery (5 mm from the cent...
Source: Cornea - May 15, 2019 Category: Opthalmology Tags: Basic Investigation Source Type: research

Blood Vessels and Lymphatic Vessels in the Cornea and Iris After Penetrating Keratoplasty
Conclusions: Our findings suggest that the iris–ciliary body could amplify immune signals and in part promote initiation of immune rejection after keratoplasty by providing a pathway for macrophages, which might participate in corneal lymphangiogenesis. (Source: Cornea)
Source: Cornea - May 15, 2019 Category: Opthalmology Tags: Basic Investigation Source Type: research

Seroprevalence of Anti-HIV-1, Anti-HIV-2, Hepatitis B Surface Antigen, and Anti-HCV in Eye Donors in a Tertiary Eye Hospital, Chennai, India, in the Past 13 years (2005–2017)
Conclusions: This retrospective study indicates that there is a trend of reduction in the seropositivity for HIV, HBV, and HCV among eye donors in Chennai over the last decade. (Source: Cornea)
Source: Cornea - May 15, 2019 Category: Opthalmology Tags: Basic Investigation Source Type: research

Keratoconus Corneal Posterior Surface Characterization According to the Degree of Visual Limitation
Purpose: To characterize posterior corneal surface features in patients with keratoconus and healthy controls and correlate them with the severity of the disease according to visual limitation. Methods: Retrospective, comparative, clinical study including 477 cases, 374 keratoconic eyes and 103 healthy corneas. Patients were classified according to the degree of visual limitation. The corneal posterior surface including shape indices and keratoconus screening indices was evaluated using the rotating Scheimpflug camera and Placido disc topographer. Results: Dioptric power of the posterior corneal surface increases l...
Source: Cornea - May 15, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Comparison of Small Incision Lenticule Extraction Surgery With and Without Cyclotorsion Error Correction for Patients With Astigmatism
Conclusions: SMILE surgery combined with cyclotorsion error compensation yielded a significant improvement in surgical outcomes regarding safety, efficiency, and predictability for patients with astigmatism. (Source: Cornea)
Source: Cornea - May 15, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Identification of a Novel ZNF469 Mutation in a Pakistani Family With Brittle Cornea Syndrome
Conclusions: This is the first report of a ZNF469 homozygous mutation causing a BCS phenotype in a consanguineous Pakistani family. Our data extend the mutation spectrum of ZNF469 variants implicated in BCS. (Source: Cornea)
Source: Cornea - May 15, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Management of Ocular Allergy Itch With an Antihistamine-Releasing Contact Lens
Conclusions: This large-scale assessment (n = 244) is the first demonstration of efficacy for CL delivery of a therapeutic for ocular allergy. Results are comparable to direct topical drug delivery and suggest that the lens/ketotifen combination can provide a means of simultaneous vision correction and treatment for CL wearers with ocular allergies. (Source: Cornea)
Source: Cornea - May 15, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Evaluation of Chemokine mRNA Expression to Assess Allergic Inflammation of the Ocular Surface in Chronic Allergic Conjunctival Diseases
Conclusions: At least 2 kinds of inflammatory reactions, IL-1α- and CXCL8-associated inflammation and CCL24- and IL-16-associated inflammation, may be involved in the exacerbation of chronic ACDs. (Source: Cornea)
Source: Cornea - May 15, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

The Use of Conjunctival Staining to Measure Ocular Surface Inflammation in Patients With Dry Eye
This study evaluated 28 patients with Sjögren syndrome (SS) DED, 28 patients with non-SS DED, and 10 controls. The messenger ribonucleic acid (mRNA) expression of inflammatory cytokines such as tumor necrosis factor-α, interleukin (IL)-1β, IL-6, interferon (IFN)-γ, IL-17, and matrix metalloproteinase 9 (MMP9) from conjunctival epithelium was investigated by real-time polymerase chain reaction. Protein expression was confirmed by immunofluorescence staining. Correlations were evaluated between the mRNA expression of inflammatory cytokines and clinical DED parameters such as ocular surface disease index...
Source: Cornea - May 15, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Efficacy of Vectored Thermal Pulsation and Warm Compress Treatments in Meibomian Gland Dysfunction: A Meta-Analysis of Randomized Controlled Trials
Conclusions: A single 12-minute VTPT was more efficacious than traditional WCT in treating DED either in objective or subjective measurements. We recommended choosing an appropriate treatment after shared decision-making. (Source: Cornea)
Source: Cornea - May 15, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

The Correlation Between Dry Eyes, Anxiety and Depression: The Sicca, Anxiety and Depression Study
Conclusions: There is a significant correlation between the severity of DED and symptoms of depression and anxiety. Effective DED treatment could have a positive impact on the symptoms of depression and anxiety. (Source: Cornea)
Source: Cornea - May 15, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Relationship Between the Degree of Iris Pigmentation and Corneal Sensitivity to a Cooling Stimulus
Purpose: To explore the relationship between the degree of iris pigmentation and corneal sensitivity threshold (CST) on a variety of different ethnicities, using the air-jet noncontact corneal aesthesiometer and by applying a consistent method of subject iris pigmentation classification. Methods: A total of 200 subjects (mean age 23.7 ± 3.1 years, 127 women) participated in this clinical cross-sectional study: 100 whites, 40 Asians, 40 Chinese, and 20 Afro-Caribbeans. CST was assessed within the central cornea using a noncontact corneal aesthesiometer, and the degree of iris pigmentation of each subject was not...
Source: Cornea - May 15, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Outcomes of Cyanoacrylate Tissue Adhesive Application in Corneal Thinning and Perforation
Conclusions: CTA application was moderately effective in stabilizing corneal perforation and thinning in the very short-term. Multiple applications are often required. Maintenance of globe integrity after glue application decreases with time and the need for surgical intervention remains high. (Source: Cornea)
Source: Cornea - May 15, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Successful Management of Herpes Simplex Keratitis With Oral Valganciclovir in Patients Unresponsive or Allergic to Conventional Antiviral Therapy
Conclusions: In case of treatment-related side effects or failure with conventional antiviral therapies, oral valganciclovir may present an alternative for the treatment and prophylaxis of HSV keratitis. (Source: Cornea)
Source: Cornea - May 15, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Transient Cornea Verticillata of Unknown Etiology: A Case Report
No abstract available (Source: Cornea)
Source: Cornea - April 2, 2019 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Reply
No abstract available (Source: Cornea)
Source: Cornea - April 2, 2019 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Letter to the Editor Re “Multicenter Study of Intense Pulsed Light Therapy for Patients With Refractory Meibomian Gland Dysfunction”
No abstract available (Source: Cornea)
Source: Cornea - April 2, 2019 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Reply
No abstract available (Source: Cornea)
Source: Cornea - April 2, 2019 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Comment on “Descemetorhexis Without Endothelial Keratoplasty Versus DMEK for Treatment of Fuchs Endothelial Corneal Dystrophy”
No abstract available (Source: Cornea)
Source: Cornea - April 2, 2019 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Sjögren's Syndrome: More Than Just Dry Eye
Conclusions: There needs to be a paradigm shift in which eye care providers and rheumatologists become more familiar with various SS-related extraglandular ocular manifestations. Existing disease activity measurement instruments must incorporate dry eye symptoms, particularly those related to visual dysfunction. An evidence-based screening algorithm for determining which patients with dry eye should be tested for underlying SS may be particularly helpful in preventing delays in diagnosis. (Source: Cornea)
Source: Cornea - April 2, 2019 Category: Opthalmology Tags: Review Source Type: research

Aspiration of Tri-folded, Endothelium-In Grafts for Descemet Membrane Endothelial Keratoplasty
Conclusions: Endothelium-in DMEK grafts may be loaded into a plastic cartridge using a skill set similar to aspiration of a scroll. (Source: Cornea)
Source: Cornea - April 2, 2019 Category: Opthalmology Tags: Techniques Source Type: research

Intraoperative Optical Coherence Tomography–Guided Femtosecond Laser–Assisted Deep Anterior Lamellar Keratoplasty
Purpose: To describe the feasibility and outcomes of intraoperative optical coherence tomography (OCT)–guided, femtosecond laser–assisted deep anterior lamellar keratoplasty in which the lamellar and tunnel cuts were completed by laser. Methods: The Ziemer Z8 system was used to scan the corneas intraoperatively and guide the stromal lamellar and tunnel cuts created by the laser. Thirty porcine eyes and 3 human cadaver globes were used to evaluate the accuracy of laser-created intrastromal tunnels and the feasibility of achieving big-bubble pneumatic dissection. The tunnel distance above the Descemet membra...
Source: Cornea - April 2, 2019 Category: Opthalmology Tags: Techniques Source Type: research

Deep Trephination Allows High Rates of Successful Pneumatic Dissection for DALK Independent of Surgical Experience
Conclusions: The standardized DALK technique using a deep trephination allows high success rates of pneumatic dissection even for surgeons inexperienced in keratoplasty. (Source: Cornea)
Source: Cornea - April 2, 2019 Category: Opthalmology Tags: Techniques Source Type: research

Deep Anterior Lamellar Keratoplasty in Eyes With Intrastromal Corneal Ring Segments
Conclusions: The presence of ICRSs facilitates gauging the depth of cannula insertion at the time of DALK, to succeed with pneumatic dissection. (Source: Cornea)
Source: Cornea - April 2, 2019 Category: Opthalmology Tags: Techniques Source Type: research

Intraoperative Optical Coherence Tomography to Guide Corneal Biopsy: A Case Report
Conclusions: Intraoperative OCT is a novel tool that assists in the identification and location of corneal pathology for biopsy. (Source: Cornea)
Source: Cornea - April 2, 2019 Category: Opthalmology Tags: Case Report Source Type: research

Crystalline Keratopathy in Post-LASIK Ectasia: A Case Report
Conclusions: This is the first known reported case of significantly delayed progressive noninfectious crystalline keratopathy in post-LASIK ectasia. The pathophysiology of this condition remains elusive to date and highlights the challenges of noninvasive diagnostic techniques and yet the utility of molecular genetic analysis in elucidating the etiology of this unique clinical presentation. (Source: Cornea)
Source: Cornea - April 2, 2019 Category: Opthalmology Tags: Case Report Source Type: research

Donor-Related Nontuberculous Mycobacterial Interface Infection After Descemet Membrane Endothelial Keratoplasty
Conclusion: This case highlights the importance of early diagnosis and intensive treatment of nontuberculous mycobacterial interface keratitis. If intensive medical therapy is able to contain infection but fails to eradicate interface keratitis, DMEK exchange is a possible treatment option. (Source: Cornea)
Source: Cornea - April 2, 2019 Category: Opthalmology Tags: Case Report Source Type: research

Inferior Quadrant of Tear Film Is More Likely to Break and Breaks Early in Patients With Dry Eyes
Purpose: To investigate the temporal and spatial distribution of tear film breakup time via a noninvasive topographer in normal subjects and patients with dry eye disease (DED). Methods: A total of 77 subjects were separated into normal and DED groups based on their symptoms and tear film instabilities. In noninvasive evaluation with Oculus Keratograph, the precorneal tear film was recorded and reconstructed into a two-dimensional map that evolved with time. Whether or not each sector broke and the breakup time if it did were recorded. The map was further grouped into 4 quadrants to reveal the spatial variation. Resu...
Source: Cornea - April 2, 2019 Category: Opthalmology Tags: Basic Investigation Source Type: research

Contralateral Eye Comparison Between 2 Cap Thicknesses in Small Incision Lenticule Extraction: 110 Versus 130 μm
Purpose: To evaluate the posterior corneal elevation (PCE) and biomechanical changes after small incision lenticule extraction (SMILE) at depths of 110 μm and 130 μm. Methods: One hundred sixteen eyes from 58 consecutive patients who underwent SMILE were included in this prospective study. Each patient underwent SMILE in one eye to a depth of 110 μm and in the other eye to a depth of 130 μm. A Scheimpflug camera and Hartmann-Shack WASCA aberrometer were used to assess the PCE and wavefront aberrations, respectively, before SMILE and at 1 and 3 months after surgery. The PCE was analyzed along 3 optical zone...
Source: Cornea - April 2, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Epi-Bowman Blunt Keratectomy Versus Diluted EtOH Epithelial Removal in Myopic Photorefractive Keratectomy: A Prospective Contralateral Eye Study
Conclusions: Our data suggest that this novel EBK device and technique may minimize postoperative pain, accelerate re-epithelialization, and offer earlier visual recovery, compared with EtOH when used for myopic PRK. (Source: Cornea)
Source: Cornea - April 2, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Long-term Chronological Changes in Very Asymmetric Keratoconus
Purpose: To investigate chronological changes in patients with very asymmetric keratoconus (KC) by Scheimpflug-based corneal tomographic evaluation. Methods: We retrospectively reviewed the clinical records of 382 patients with KC attending a university hospital. Patients who were diagnosed with KC in one eye and forme fruste keratoconus in the other eye at the last visit and followed up with Scheimpflug-based tomographic corneal imaging were included. The anterior radius of curvature (ARC) and posterior radius of curvature (PRC) obtained at a 3.0-mm optical zone and the thinnest pachymetry reading of corneal thicknes...
Source: Cornea - April 2, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Vision-Related Quality of Life in Keratoconus: A Save Sight Keratoconus Registry Study
Purpose: To assess vision-related quality of life using the Impact of Vision Impairment Questionnaire (IVI) in patients with keratoconus enrolled in the Save Sight Keratoconus Registry. Methods: In this cross-sectional study, data on 107 keratoconic patients were collected through a prospectively designed web-based registry from a quaternary referral eye hospital and 2 corneal subspecialty practices. Vision-related quality of life was evaluated using the IVI. Rasch analysis was used to transform the IVI responses into interval-level measures comprising reading, mobility, and emotional well-being subscales. Association...
Source: Cornea - April 2, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Measurement of Corneal Biomechanical Properties in Diabetes Mellitus Using the Ocular Response Analyzer and the Corvis ST
Purpose: Hyperglycemia in diabetes mellitus (DM) might induce changes in corneal biomechanics. Therefore, biomechanical properties of the cornea were measured using the ocular response analyzer and the Corvis ST. Methods: In the study, 35 eyes of 35 diabetic patients were included. After an ophthalmological examination, measurements with the ocular response analyzer and the Corvis ST were taken. Additionally, biometry and corneal topography were performed and HbA1c values were collected. Results were compared to an age-, pachymetry- and intraocular pressure-matched group of 35 healthy subjects. Results: Mean age (6...
Source: Cornea - April 2, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Evaluation of the Ocular Surface in Different Contact Lens Replacement Schedules
Purpose: To evaluate the effects of different contact lens (CL) replacement schedules and different CL materials on the ocular surface and tear function. Methods: Daily disposable hydrogel CLs were given to group 1 (n = 22), daily disposable silicone hydrogel CLs were given to group 2 (n = 25), and reusable silicone hydrogel CLs were given to group 3 (n = 24). Tear function tests and inflammatory cytokine [interleukin (IL)-6, IL-8, IL-17A, and matrix metalloproteinase (MMP)-9] levels were evaluated before and at 1 and 3 months after CL usage. Impression cytology was evaluated before and at 3 months after CL usage. Re...
Source: Cornea - April 2, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Evaluation of Dry Eye Disease in Children With Systemic Lupus Erythematosus and Healthy Controls
Conclusions: There is discordance between symptoms and signs of DED in children with SLE. Corneal fluorescein staining is essential for the diagnosis of DED in these children. (Source: Cornea)
Source: Cornea - April 2, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Validation of Alternative Methods for Detecting Meibomian Gland Dropout Without an Infrared Light System: Red Filter for Simple and Effective Meibography
Purpose: To evaluate the validity and reliability of alternative methods for evaluating meibomian gland (MG) dropout without using an infrared light system: red-filtered or isolated red-channel images (RCIs) of the everted eyelid. Methods: We evaluated MG dropout in the everted upper and lower eyelids of 125 eyes of 64 patients with good-quality infrared meibography images (IMIs) and color digital photographs with and without a red filter. Red-filtered images (RFIs) were converted to black and white and adjusted for contrast/brightness [adjusted red-filtered images (aRFIs)]. RCIs were computationally isolated from col...
Source: Cornea - April 2, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Efficacy of Omega-3 Fatty Acid Supplementation for Treatment of Dry Eye Disease: A Meta-Analysis of Randomized Clinical Trials
Purpose: To assess whether omega-3 fatty acid (FA) supplementation is more efficacious than placebo in amelioration of signs and symptoms of dry eye disease. Methods: We performed a systematic literature search in PubMed, Scopus, Web of Science, and Cochrane Central Register of Controlled Trials databases. We included randomized clinical trials comparing omega-3 FA supplementation with placebo in patients with dry eye disease. The outcome measures were dry eye symptoms, breakup time (BUT), Schirmer test, and corneal fluorescein staining. The pooled effect sizes were estimated using a random-effects model. Heterogeneit...
Source: Cornea - April 2, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Effect of Anti–Vascular Endothelial Growth Factor Therapy on Corneal Nerves
Purpose: Vascular endothelial growth factor (VEGF) is a trophic factor for corneal nerves (CNs). Despite its widespread use to treat a variety of retinal diseases, the effect of repetitive intravitreal (IV) anti-VEGF injections on CN is not known. Methods: Retrospective case–control study. CN parameters were compared between eyes in 39 individuals who received anti-VEGF injections in one eye only. Next, we compared CN parameters between 50 eyes of 50 individuals with a history of IV anti-VEGF injections and 80 eyes of 80 individuals without a history of injection. In vivo confocal microscopic examination was con...
Source: Cornea - April 2, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Therapeutic Challenges and Prognosis of Descemet's Membrane Endothelial Keratoplasty in Herpes Simplex Eye Disease
Purpose: To describe the functional outcome, postoperative complications, and complication management of Descemet's membrane endothelial keratoplasty (DMEK) in corneal decompensation secondary to Herpes simplex eye disease (HED). Methods: This retrospective interventional case series included 17 eyes that received DMEK for endothelial decompensation secondary to HED. Complete ophthalmological examination, including corrected-distance visual acuity (CDVA), anterior segment slit-lamp, and optical coherence tomography assessment, were performed preoperatively and postoperatively at regular follow-up intervals. Visual out...
Source: Cornea - April 2, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Recent Surgical Trends in Pediatric Corneal Transplantation: A 13-Year Review
Purpose: Corneal transplantation is the standard of care for pediatric corneal opacities, but little consensus exists on optimal surgical management. Our goal was to evaluate cross-sectional data of donor and recipient characteristics collected from eye banks providing tissue for pediatric corneal transplant cases to assess surgical trends in pediatric keratoplasty over the past 13 years. Methods: We performed a retrospective review of recipient data, collected from 4 major eye banks, for pediatric patients ( (Source: Cornea)
Source: Cornea - April 2, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Micropulse Transscleral Cyclophotocoagulation in Keratoplasty Eyes
Purpose: To assess the outcomes of micropulse transscleral cyclophotocoagulation for intraocular pressure (IOP) control in keratoplasty eyes. Methods: Outcomes of micropulse laser treatments of postkeratoplasty eyes were retrospectively reviewed. IOP was assessed with applanation tonometry. Keratoplasty survival was calculated with Kaplan–Meier survival analysis. Results: Sixty-one eyes in 57 patients received laser treatment; 31 eyes received 1, 21 received 2, 8 received 3, and 1 received 4 treatments. The median follow-up was 21 months (range, 2–35 months). At baseline, the mean IOP was 28 ± 11...
Source: Cornea - April 2, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Keratometric, Pachymetric, and Surface Elevation Characterization of Corneas With Fuchs Endothelial Corneal Dystrophy Treated With DMEK
Purpose: To characterize pachymetric, keratometric, and surface elevation parameters in pseudophakic eyes with Fuchs dystrophy that underwent Descemet membrane endothelial keratoplasty (DMEK) and to compare these characteristics with those in normal pseudophakic eyes. Methods: Postoperative corneal tomography with a median follow-up of 20 months was evaluated using the Pentacam tomographer on 46 DMEK eyes. Results were compared with data from an age-matched cohort of 46 normal eyes. Parameters included curvature analysis, keratometry values, corneal thickness (CT), pachymetric progression index, Ambrósio relati...
Source: Cornea - April 2, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research