“Corneal Plication” for the Management of Progressive Corneal Graft Protrusion in Patients With Keratoconus: a New Technique
Conclusions: Corneal graft plication may represent a realistic alternative to more invasive procedures, currently used for the management of this long-term post-PKP complication in patients with keratoconus because it is a nonperforating technique that seems to provide satisfactory anatomical and visual outcomes without the need for any tissue excision or regrafting. (Source: Cornea)
Source: Cornea - February 9, 2022 Category: Opthalmology Tags: Case Report Source Type: research

Bilateral Corneal Ectasia 3 Years After Small Incision Lenticule Extraction in a Borderline Case
Conclusions: There are a very few reports of corneal ectasia after SMILE with normal preoperative topography. (Source: Cornea)
Source: Cornea - February 9, 2022 Category: Opthalmology Tags: Case Report Source Type: research

First Clinical Experience With Ophthalmic e-Device for Unaided Patient Self-Examination During COVID-19 Lockdown
Conclusions: An e-Device for combined BCVA self-measurement and biomicroscopy self-imaging may have potential as an aid in remote ophthalmic examination in the absence of an ophthalmic professional and may be considered for patients who are unable to visit an ophthalmic clinic for routine follow-up. (Source: Cornea)
Source: Cornea - February 9, 2022 Category: Opthalmology Tags: Basic Investigation Source Type: research

Fungal Keratitis: Diagnostic Characteristics of the Potassium Hydroxide Preparation With Calcofluor White in Northern California
Conclusions: The observed sensitivity and specificity of the KOH–CFW preparation are significantly lower than many previously reported values. In regions with low incidence of fungal keratitis, the KOH–CFW preparation may have diagnostic performance similar to that of the clinical impression formed only on the basis of history and physical examination. (Source: Cornea)
Source: Cornea - February 9, 2022 Category: Opthalmology Tags: Basic Investigation Source Type: research

Complications of Adenoviral Keratoconjunctivitis in Ophthalmologists and Orthoptists: Epidemiology and Risk Factor, A Retrospective Questionnaire Analysis
Conclusions: AK and SEI affect a large proportion of ophthalmologists and orthoptists, possibly for years, with high morbidity leading to occupational discomfort. Few practitioners asked for either to be recognized as an occupational disease. Associated factors would require a dedicated study. (Source: Cornea)
Source: Cornea - February 9, 2022 Category: Opthalmology Tags: Basic Investigation Source Type: research

Acellular Porcine Cornea Produced by Supercritical Carbon Dioxide Extraction: A Potential Substitute for Human Corneal Regeneration
Conclusions: APC manufactured by SCCO2 technology revealed complete cells and non-collagenous protein removal compared with the Triton–sodium dodecyl sulfate decellularization process. APC showed excellent biocompatibility in rabbit lamellar corneal transplantation with a follow-up to 1 year. APC can be a potential substitute for human-donated cornea for corneal transplantation in the near future. (Source: Cornea)
Source: Cornea - February 9, 2022 Category: Opthalmology Tags: Basic Investigation Source Type: research

The Impact of the COVID-19 Pandemic on Corneal Transplantation in Brazil
Purpose: The purpose of this study was to evaluate the impact of the coronavirus disease 2019 pandemic on corneal transplantation (CT) in Brazil. Methods: Data from patients who underwent CT at the Hospital Oftalmológico de Sorocaba (HOS), Brazil, were analyzed. National and state numbers of keratoplasties, patients added to the CT waiting list, and total patients on the waiting list were also obtained. Baseline prepandemic (from January 1, 2019, to March 31, 2020) data were compared with 2 time frames of the coronavirus disease 2019 pandemic: elective CT suspension period (between April 1, 2020, and September ...
Source: Cornea - February 9, 2022 Category: Opthalmology Tags: Clinical Science Source Type: research

Corneal Nerve Fiber and Sensitivity Loss After Repeated Intravitreal Anti-VEGF Injections: An In Vivo Confocal Microscopy Study
Conclusions: Corneal SBNP parameters were affected, corneal sensitivity was decreased, and OSDI scores were increased in patients with multiple intravitreal anti-VEGF injections. IVCM parameters were not significantly different between AMD and DME groups. (Source: Cornea)
Source: Cornea - February 9, 2022 Category: Opthalmology Tags: Clinical Science Source Type: research

Reliability of Several Glaucoma Tests in Patients With Boston Type 1 Keratoprosthesis
Conclusions: The 10-2 visual field and RNFL thickness seem sufficiently repeatable and might allow the detection of glaucoma progression in KPro eyes. Such testing is important, given limited inter-rater agreement regarding the palpation IOP estimate. (Source: Cornea)
Source: Cornea - February 9, 2022 Category: Opthalmology Tags: Clinical Science Source Type: research

Long-Term Outcome of Descemet Membrane Endothelial Keratoplasty in Eyes With Fuchs Endothelial Corneal Dystrophy Versus Pseudophakic Bullous Keratopathy
Purpose: The aim of this study was to compare the long-term outcome of Descemet membrane endothelial keratoplasty (DMEK) in patients with Fuchs endothelial corneal dystrophy (FECD) and pseudophakic bullous keratopathy (PBK). Methods: Records of consecutive DMEK surgeries performed between 2015 and 2016 at the Department of Ophthalmology, Cologne, Germany, were retrospectively reviewed from the prospective Cologne DMEK Database. Eyes with either PBK or FECD with a complete 3-year follow-up were enrolled. Main outcome parameters included central corneal thickness (CCT), peripheral corneal thickness (PCT), best spe...
Source: Cornea - February 9, 2022 Category: Opthalmology Tags: Clinical Science Source Type: research

Ocular Surface Squamous Neoplasia With Coexistent Microbial Keratitis: Incidence, Risk Factors, Clinical Features, Microbiological Profile, and Treatment Outcome
Conclusions: Rarely, MK can coexist with OSSN leading to a poor treatment outcome. Male sex, human immunodeficiency virus seropositivity, large limbal pigmented OSSN lesion with keratin and corneal component, noduloulcerative morphology, and scleral invasion were risk factors for this association. (Source: Cornea)
Source: Cornea - February 9, 2022 Category: Opthalmology Tags: Clinical Science Source Type: research

Bilateral Increase of Matrix Metalloproteinase-9 Expression in Tears After the Unilateral Decrease of Corneal Sensitivity
Conclusions: Patients with the unilateral neurotrophic keratitis demonstrated a significant bilateral increase of the MMP-9 expression in the tear film as compared with controls. Despite the tearing reflex and corneal surface barrier being preserved in the unaffected contralateral eyes, it is necessary to pay attention to the possible attenuation of meibomian gland function in the opposite eyes as well. (Source: Cornea)
Source: Cornea - February 9, 2022 Category: Opthalmology Tags: Clinical Science Source Type: research

Freeze-Dried Versus Cryopreserved Amniotic Membranes in Corneal Ulcers Treated by Overlay Transplantation: A Case–Control Study
Conclusions: This is the first study that provides positive insight into the effectiveness of FD-AM compared with C-AM when used as overlay transplantation for treating corneal ulcers. (Source: Cornea)
Source: Cornea - February 9, 2022 Category: Opthalmology Tags: Clinical Science Source Type: research

Astigmatic Vectorial Analysis in Pediatric Keratoconus After Unilateral Cross-Linking Treatment
Purpose: The aims of this study were to evaluate the treatment response of pediatric keratoconus (KC) patients to unilateral corneal collagen cross-linking (CXL) in treated eyes, disease progression in untreated eyes, and define the predictive value of astigmatic parameters by astigmatic vectorial analysis. Methods: Pediatric patients with KC with CXL-treated progressive eye and untreated fellow eye were included. Patients with other ocular conditions and a history of previous ocular surgery were excluded. Astigmatic changes in anterior and posterior corneal surfaces were evaluated with vectorial analysis. The r...
Source: Cornea - February 9, 2022 Category: Opthalmology Tags: Clinical Science Source Type: research

Descemet Stripping Only for Fuchs Endothelial Corneal Dystrophy: Will It Become the Gold Standard?
This article describes the history of the development of DSO, its current status, and what successful DSO tells us about the pathophysiology of FECD. Remaining questions and future directions are also highlighted. (Source: Cornea)
Source: Cornea - February 9, 2022 Category: Opthalmology Tags: Invited Submission Source Type: research