Management of Keratoconus in Down Syndrome and Other Intellectual Disability
Conclusions:
KC is strikingly prevalent in the ID population. Ireland has the highest rate of Down syndrome in Europe (26.3:10,000 live births). This group is rarely suitable for corneal transplantation, and corneal collagen crosslinking is an effective intervention to prevent progression to advanced KC in this already socially restricted group. We propose an algorithm for investigation/treatment and also recommend uniform pediatric KC screening/treatment in ID populations. (Source: Cornea)
Source: Cornea - March 10, 2022 Category: Opthalmology Tags: Clinical Science Source Type: research
Best Indicators for Detecting Keratoconus Progression in Children: A Report From the Shahroud Schoolchildren Eye Cohort Study
Conclusions:
According to our findings, changes in index of height decentration, Zonal Kmax-3 mm, refractive astigmatism, single point Kmax, and index of vertical asymmetry are the best indices for detecting KC progression in children younger than 12 years. (Source: Cornea)
Source: Cornea - March 10, 2022 Category: Opthalmology Tags: Clinical Science Source Type: research
Impact of Graves Disease on Ocular Surface and Corneal Epithelial Thickness in Patients With and Without Graves Orbitopathy
Conclusions:
GD negatively influenced ocular surface and CET, with a higher level of eye dryness and corneal thinning regardless of GO status, suggesting that subclinical chronic inflammation may play a role in the pathogenesis of tear film and ocular surface stability. (Source: Cornea)
Source: Cornea - March 10, 2022 Category: Opthalmology Tags: Clinical Science Source Type: research
Clinical Outcomes of a New Type of Continuous Intrastromal Corneal Ring for Treatment of Keratoconus
This study was conducted on 95 contact lens–intolerant keratoconic eyes with clear central corneas. A continuous corneal ring, annular intrastromal corneal inlay (AICI), was inserted using femtosecond laser in all cases. Patients were followed up for 1, 3, and 12 months postsurgery. Visual and subjective refractive outcomes were evaluated in each examination. Besides, keratometry and aberrometric values were recorded before and 12 months after surgery. Finally, vector analysis of refractive astigmatism was performed using the Alpins method.
Results:
The uncorrected and corrected distance visual acuities improved s...
Source: Cornea - March 10, 2022 Category: Opthalmology Tags: Clinical Science Source Type: research
Efficacy of Topical Ivermectin 1% in the Treatment of Demodex Blepharitis
Conclusions:
In patients with Demodex blepharitis, the use of topical ivermectin 1% cream for 15 minutes once weekly in addition to eyelid hygiene had more significantly improved symptoms, ocular surface staining, eyelid debris, redness/swelling, and telangiectasia as compared with eyelid hygiene alone. These findings support the efficacy of topical ivermectin 1% cream application in the treatment of Demodex blepharitis. (Source: Cornea)
Source: Cornea - March 10, 2022 Category: Opthalmology Tags: Clinical Science Source Type: research
TearCare for the Treatment of Meibomian Gland Dysfunction in Adult Patients With Dry Eye Disease: A Masked Randomized Controlled Trial
Purpose:
The aim of this study was to demonstrate the safety and effectiveness of a single TearCare procedure compared with a single LipiFlow procedure in treatment of the dry eye disease associated with meibomian gland dysfunction.
Methods:
In a multicenter, masked, randomized controlled trial, 135 subjects received a single TearCare (TC) treatment (n = 67) or a single LipiFlow (LF) treatment (n = 68) at baseline and were followed up for 1 month posttreatment. Tear film breakup time, meibomian gland function, and corneal and conjunctival staining scores were assessed as dry eye signs at baseline, 2 weeks, and 1...
Source: Cornea - March 10, 2022 Category: Opthalmology Tags: Clinical Science Source Type: research
Outcomes After Corneal Crosslinking for Keratoconus in Children and Young Adults
Conclusions:
Corneal crosslinking stabilizes, and in some cases improves, visual and corneal parameters in pediatric and young adult patients with keratoconus. The procedure is safe and well-tolerated and may prevent keratoconus progression in young patients. (Source: Cornea)
Source: Cornea - March 10, 2022 Category: Opthalmology Tags: Clinical Science Source Type: research
Corneal Neurotization: A Novel Surgical Procedure for Neurotrophic Keratopathy
Conclusions:
CN represents a game-changing surgical procedure for NK, which has the potential to restore corneal sensitivity in all stages of the disease regardless of the mechanism of denervation. Further long-term results are needed to confirm its efficacy over time. The design of randomized clinical trials comparing CN with noninterventional therapies could further validate the adoption of this technique. (Source: Cornea)
Source: Cornea - March 10, 2022 Category: Opthalmology Tags: Invited Submission Source Type: research
Therapeutic Corneal Transplantation in Acanthamoeba Keratitis: Penetrating Versus Lamellar Keratoplasty
Conclusions:
After AK resolution by 6 to 12 months of medical treatment, OPK seems to be the best surgical choice in patients with AK. If AK could not be eradicated by medical therapy, TDALK may be chosen in the early disease stage and TPK in later stages. (Source: Cornea)
Source: Cornea - February 9, 2022 Category: Opthalmology Tags: Review Source Type: research
Examining Corneal Tissue Exportation Fee and Its Impact on Equitable Allocation
This article describes the fee structures and determines whether they support or hinder the equitable allocation of corneal tissue. (Source: Cornea)
Source: Cornea - February 9, 2022 Category: Opthalmology Tags: Review Source Type: research
Remote Surgeon Virtual Presence: A Novel Telementoring Method for Live Surgical Training
Conclusions:
Telementoring is a promising tool that can traverse large distances for ophthalmic education. (Source: Cornea)
Source: Cornea - February 9, 2022 Category: Opthalmology Tags: Techniques Source Type: research
Modified procedure for Loading “Flat” DMEK Grafts Into an Injector
Conclusions:
ECL was not significantly different in grafts prepared using a drop-in loading procedure compared with grafts prepared using the standard suction protocol. The drop-in loading protocol may be particularly useful to surgeons who load their own grafts and eye bank processing technicians who encounter a “flat” DMEK graft that does not scroll or a loosely scrolled DMEK graft. (Source: Cornea)
Source: Cornea - February 9, 2022 Category: Opthalmology Tags: Techniques Source Type: research
Rescue Technique to Solve Postoperative Refractory Double Anterior Chamber in Deep Anterior Lamellar Keratoplasty
Conclusions:
Macroperforation of Descemet membrane during DALK with incomplete removal of the stroma can lead to persistent double anterior chamber. This complication could be solved by the technique devised by this study. (Source: Cornea)
Source: Cornea - February 9, 2022 Category: Opthalmology Tags: Techniques Source Type: research
Manual DALK in Keratoconus: An Ex Vivo Light and Transmission Electron Microscopy Analysis 2 Years After Surgery
Conclusions:
This study confirmed the available clinical and confocal studies that show progressive stromal remodeling after manual DALK. Two years after surgery, no posterior stromal interface was detected. (Source: Cornea)
Source: Cornea - February 9, 2022 Category: Opthalmology Tags: Case Report Source Type: research
Methamphetamine-Induced Keratitis Case Series
Abstract:
Methamphetamine-induced keratitis is a recognized but not widely studied cause of corneal stromalysis and infections. These 2 cases describe the presentation and clinical course of keratitis in patients with preceding methamphetamine use. (Source: Cornea)
Source: Cornea - February 9, 2022 Category: Opthalmology Tags: Case Report Source Type: research
