Tyrosine Kinase Inhibitor, Vatalanib, Inhibits Proliferation and Migration of Human Pterygial Fibroblasts
Conclusions: These results indicate that vatalanib significantly suppressed the proliferation and migration of HPFs by decreasing vascular endothelial growth factor and transforming growth factor-β. Vatalanib showed less toxicity than that of MMC. Based on these results, vatalanib may potentially serve as a new adjuvant treatment after pterygium excision surgery. (Source: Cornea)
Source: Cornea - August 9, 2017 Category: Opthalmology Tags: Basic Investigation Source Type: research

Comparison of Collagen Cross-Linking and Amniotic Membrane Transplantation in an Experimental Alkali Burn Rabbit Model
Conclusions: CXL treatment is an effective adjuvant treatment for promoting reepithelialization, reducing inflammation and neovascularization, and preventing ulceration in acute alkali burns. Providing AMT after suppressing inflammation may be a more effective treatment. (Source: Cornea)
Source: Cornea - August 9, 2017 Category: Opthalmology Tags: Basic Investigation Source Type: research

Topical Tacrolimus for Corneal Subepithelial Infiltrates Secondary to Adenoviral Keratoconjunctivitis
Conclusions: Topical tacrolimus, compounded in the pharmacy, seems to be an effective and safe alternative for the treatment of SEIs secondary to adenovirus keratoconjunctivitis. (Source: Cornea)
Source: Cornea - August 9, 2017 Category: Opthalmology Tags: Clinical Science Source Type: research

The Role of the Back Plate in Angle Anatomy with the Boston Type I Keratoprosthesis
Conclusions: We successfully visualized the angle anatomy in 66.1% of the imaged eyes, including all BPs studied. Neither the material nor the size of the B-KPro BP had a significant impact on the angle anatomy. (Source: Cornea)
Source: Cornea - August 9, 2017 Category: Opthalmology Tags: Clinical Science Source Type: research

Prevention and Management of Descemet Membrane Endothelial Keratoplasty Complications
Conclusions: DMEK shows acceptable rates of complications up to 2 years after surgery, which can be managed successfully. Anticipation of potential challenges and difficulties may aid in modifying intraoperative strategies for predisposed eyes. This knowledge may further minimize complications, in particular, when performing DMEK for an extended spectrum of corneal endothelial disorders. (Source: Cornea)
Source: Cornea - August 9, 2017 Category: Opthalmology Tags: Clinical Science Source Type: research

Validation of Catquest-9SF—A Visual Disability Instrument to Evaluate Patient Function After Corneal Transplantation
Conclusions: Rasch analysis showed that Catquest-9SF is a valid instrument for measuring visual disability in patients who have undergone corneal transplantation primarily to improve vision. (Source: Cornea)
Source: Cornea - August 9, 2017 Category: Opthalmology Tags: Clinical Science Source Type: research

Immunologic Rejection Episodes After Deep Anterior Lamellar Keratoplasty: Incidence and Risk Factors
Conclusions: This study demonstrates the substantial rate of rejection episodes that can be induced by corneal stroma in DALK and suggests that postoperative topical corticosteroids should be continued longer than the study's 7-week median and that young African Americans need higher-dose, longer-duration topical corticosteroids. The association between the side-cut method and rejection risk merits further investigation. (Source: Cornea)
Source: Cornea - August 9, 2017 Category: Opthalmology Tags: Clinical Science Source Type: research

Superficial Automated Keratopigmentation for Iris and Pupil Simulation Using Micronized Mineral Pigments and a New Puncturing Device: Experimental Study
Conclusions: SAK using a new automated puncture device and micronized mineral pigments achieved good cosmetic outcomes for iris and pupil simulation. This method could be a valid alternative to treat serious cosmetic eye problems that affect the superficial cornea or functional problems, such as photophobia or diplopia secondary to iris defects or trauma. (Source: Cornea)
Source: Cornea - August 9, 2017 Category: Opthalmology Tags: Clinical Science Source Type: research

Effect of a New Matrix Therapy Agent in Persistent Epithelial Defects After Bacterial Keratitis Treated With Topical Fortified Antibiotics
Purpose: To evaluate the effect of topical application of a matrix regenerating agent (RGTA) in subjects with a persistent epithelial defect after bacterial keratitis treated with topical fortified antibiotics. Methods: In this prospective case series of 14 subjects (14 eyes) with a persisting corneal ulcer after the cessation of fortified antibiotics, subjects were treated with an RGTA at a dose of 1 drop every other day. The main outcome measure was the proportion of subjects with complete corneal healing 1 month after initiation of treatment. The secondary outcome measures were the size and depth of corneal ulceration ...
Source: Cornea - August 9, 2017 Category: Opthalmology Tags: Clinical Science Source Type: research

Determination of the Minimal Clinically Important Difference of the University of North Carolina Dry Eye Management Scale
Conclusions: The UNC DEMS is a valid, responsive patient-reported outcome measure instrument, which is easy to use in the clinic and capable of showing an MCID of 1 point. (Source: Cornea)
Source: Cornea - August 9, 2017 Category: Opthalmology Tags: Clinical Science Source Type: research

Interrelationships Between 3 Keratoconic Cone Parameters
Purpose: To find out the interrelationships between 3 parameters of the keratoconic cone. Methods: A total of 101 keratoconic eyes of 58 patients were included in this retrospective case series study. A complete eye examination was performed. Kmax (K) and pachymetry at the thinnest point (T) were obtained from the Pentacam tomographer. The vertex to thinnest pachymetry distance (D for decentration) was calculated using trigonometry. Pearson correlation coefficients between T and D, between T and K, and between D and K were calculated. Results: There is a statistically significant positive correlation between thinnest poi...
Source: Cornea - August 9, 2017 Category: Opthalmology Tags: Clinical Science Source Type: research

Effect of the Learning Curve on Visual and Refractive Outcomes of Small-Incision Lenticule Extraction
Conclusions: Our study showed that faster visual recovery, better safety profile, and more accurate astigmatic correction could be attained with increasing surgical experience. (Source: Cornea)
Source: Cornea - August 9, 2017 Category: Opthalmology Tags: Clinical Science Source Type: research

Induced De Novo Astigmatism After Hyperopic LASIK Versus Myopic LASIK Surgery in Nonastigmatic Eyes
Purpose: To compare the astigmatism induced surgically (SIA) by spherical hyperopic laser in situ keratomileusis (H-LASIK) versus myopic laser in situ keratomileusis (M-LASIK) in nonastigmatic eyes. Methods: A retrospective study of patients who underwent LASIK surgery between 2005 and 2014 at the Care-Vision Laser Center, Israel. We calculated the mean absolute SIA and performed risk factor analysis for induced astigmatism. Differences between H-LASIK and M-LASIK were analyzed. Results: Eyes of 3877 patients who underwent M-LASIK and of 549 patients who underwent H-LASIK were nonastigmatic preoperatively and received a ...
Source: Cornea - August 9, 2017 Category: Opthalmology Tags: Clinical Science Source Type: research

Incidence of Posterior Vitreous Detachment After Femtosecond LASIK Compared With Microkeratome LASIK
Purpose: To compare the incidence of posterior vitreous detachment (PVD) after femtosecond and microkeratome laser in situ keratomileusis (LASIK). Setting: Rowad Correction Centre, Cairo, Egypt (a private center affiliated to Cairo University). Design: Prospective, nonrandomized comparative unmasked study. Methods: The study was conducted at a single laser center. Eligible patients chose between femtosecond and microkeratome LASIK after appropriate counseling. B-scan ultrasonography was performed before surgery by a single operator. Patients with preexisting PVD (partial or complete) were excluded. The axial length was ...
Source: Cornea - August 9, 2017 Category: Opthalmology Tags: Clinical Science Source Type: research

Long-Term Ocular Surface Stability in Conjunctival Limbal Autograft Donor Eyes
Conclusions: With the advent of newer ocular surface transplantation methods, there has been concern that CLAU carries the theoretical risk of inducing LSCD. Our long-term clinical results following donor eyes after CLAU demonstrate no signs of LSCD. (Source: Cornea)
Source: Cornea - August 9, 2017 Category: Opthalmology Tags: Clinical Science Source Type: research

Outcomes of Keratoplasty After Ocular Surface Stem Cell Transplantation
Purpose: To investigate the long-term outcomes of penetrating keratoplasty (PK) and deep anterior lamellar keratoplasty (DALK) after ocular surface stem cell transplantation (OSST). Methods: An observational retrospective review was performed on all patients who underwent OSST followed by either PK or DALK with a minimum of 6-month follow-up. Results: One hundred two eyes fulfilled the inclusion criteria. The mean time to keratoplasty after OSST was 19 months, and the mean follow-up was 57 months after keratoplasty. A Kaplan–Meier analysis demonstrated 92% graft survival at year 1, 77% at year 2, 62% at year 3, 55%...
Source: Cornea - August 9, 2017 Category: Opthalmology Tags: Clinical Science Source Type: research

Reply
No abstract available (Source: Cornea)
Source: Cornea - July 10, 2017 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Comment on Advantages of Anterior Segment Optical Coherence Tomography Evaluation of the Kayser–Fleischer Ring in Wilson Disease
No abstract available (Source: Cornea)
Source: Cornea - July 10, 2017 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Reply
No abstract available (Source: Cornea)
Source: Cornea - July 10, 2017 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Spontaneous Canalicular Plug Erosion After Punctal Plug Placement
No abstract available (Source: Cornea)
Source: Cornea - July 10, 2017 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Fuchs Endothelial Corneal Dystrophy in a Child
No abstract available (Source: Cornea)
Source: Cornea - July 10, 2017 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Management of Corneal Scarring Secondary to Herpes Zoster Keratitis
Conclusions: Patients with visually significant corneal scarring secondary to HZK may have good outcomes with the appropriate medical and surgical considerations, particularly in the absence of active ocular surface disease and inflammation. Those with active disease may benefit from delaying surgical intervention until a satisfactory quiescent period has been achieved. Prospective studies, such as the proposed Zoster Eye Disease Study, are imperative for validating these principles and determining evidence-based management guidelines. (Source: Cornea)
Source: Cornea - July 10, 2017 Category: Opthalmology Tags: Review Source Type: research

Selective Localized Tenonplasty for Corneal Burns Based on the Findings of Ocular Surface Fluorescein Angiography
Conclusions: We observed acceptable outcomes in our patients after selective tenonplasty based on ocular surface angiography. (Source: Cornea)
Source: Cornea - July 10, 2017 Category: Opthalmology Tags: Techniques Source Type: research

Air Pump–Assisted Graft Centration, Graft Edge Unfolding, and Graft Uncreasing in Young Donor Graft Pre-Descemet Endothelial Keratoplasty
Conclusions: Although very young donor grafts may be used for PDEK, they are difficult to center and unroll completely before floating against host stroma. An air pump–assisted technique using continuous pressurized air infusion allows successful final graft positioning even with very young donor corneas. It thus makes surgery easier as several key steps are made easier to handle. It additionally helps in tamponading hemorrhage during peripheral iridectomy, increasing surgical space, preventing fluctuations in the anterior chamber depth, and promoting graft adherence. (Source: Cornea)
Source: Cornea - July 10, 2017 Category: Opthalmology Tags: Techniques Source Type: research

Probable Donor-Derived Cytomegalovirus Disease After Keratolimbal Allograft Transplantation
Conclusions: We present the first case of CMV disease in a seronegative patient who received a presumed CMV-seropositive donor KLAL. Similar to solid organ transplantation, prophylactic and therapeutic management of CMV infection is necessary in the setting of systemic immunosuppression. (Source: Cornea)
Source: Cornea - July 10, 2017 Category: Opthalmology Tags: Case Report Source Type: research

Regression of Inflamed Pterygia by Frequent High-Dose Intralesional Ziv-Aflibercept
Conclusions: Frequent high-dose intralesional ziv-aflibercept can lead to regression and/or retraction of inflamed pterygia in this pilot study. Clinical Trial Registration: https://clinicaltrials.gov , NCT02486484. (Source: Cornea)
Source: Cornea - July 10, 2017 Category: Opthalmology Tags: Case Report Source Type: research

Water Exposure is a Common Risk Behavior Among Soft and Gas-Permeable Contact Lens Wearers
Purpose: To understand soft contact lens (SCL) and gas-permeable (GP) lens wearers' behaviors and knowledge regarding exposure of lenses to water. Methods: The Contact Lens Risk Survey (CLRS) and health behavior questions were completed online by a convenience sample of 1056 SCL and 85 GP lens wearers aged 20 to 76 years. Participants were asked about exposing their lenses to water and their understanding of risks associated with these behaviors. Chi-square analyses examined relationships between patient behaviors and perceptions. Results: GP lens wearers were more likely than SCL wearers to ever rinse or store lenses in...
Source: Cornea - July 10, 2017 Category: Opthalmology Tags: Basic Investigation Source Type: research

Corneal Endothelial Cells Have an Absolute Requirement for Cysteine for Survival
Purpose: The aim of this study was to evaluate which amino acid(s) among the 20 standard protein amino acids is indispensable for the survival of cultured human corneal endothelial cells (HCECs). Methods: HCECs were cultured in amino acid screening media that were missing 1 specific amino acid, and cell growth was evaluated. After this first selection, we conducted a further evaluation of cell growth in response to the addition of 4 amino acids (cysteine, methionine, valine, and arginine) to amino acid-free culture media. We then evaluated the antioxidant effect of cysteine compared with other antioxidants in terms of apo...
Source: Cornea - July 10, 2017 Category: Opthalmology Tags: Basic Investigation Source Type: research

Ocular Surface Changes After Sulfur Mustard Exposure in Rabbits, Monitored by Impression Cytology
Conclusions: Continuous monitoring of the ocular surface after SM exposure by IC enables earlier detection of pathology and therapeutic intervention, therefore, is recommended for routine follow-up of casualties. Prolonged loss of goblet cells may point toward the role of mucin in the pathogenesis. (Source: Cornea)
Source: Cornea - July 10, 2017 Category: Opthalmology Tags: Basic Investigation Source Type: research

Further Analysis of the Predictability of Corneal Endothelial Cell Density Estimates When Polymegethism Is Present
Conclusions: Higher values of corneal endothelial polymegethism result in predictable increases in the variability (uncertainty) in ECD estimates, thus reducing the “accuracy” of ECD values. There is no obvious utility in assessing more than 100 cells in such endothelia. (Source: Cornea)
Source: Cornea - July 10, 2017 Category: Opthalmology Tags: Clinical Science Source Type: research

Influence of Refractive Status on the Higher-Order Aberration Pattern After Small Incision Lenticule Extraction Surgery
Purpose: To study the effect of myopia on the pattern change in higher-order aberrations after small incision lenticule extraction. Methods: Sixty eyes of 60 patients were included: low myopia (≤−3.00 D), moderate myopia (−3.00 D to −6.00 D), and high myopia (≥−6.00 D). Total higher-order aberrations (tHOA), vertical coma ( ), horizontal coma ( ), and spherical aberration ( ) were measured preoperatively and at postoperative 3 months. Results: At the end of 3 months, tHOA changed significantly compared with the preoperative values (P (Source: Cornea)
Source: Cornea - July 10, 2017 Category: Opthalmology Tags: Clinical Science Source Type: research

Corneal Breakthrough Haze After Photorefractive Keratectomy With Mitomycin C: Incidence and Risk Factors
Purpose: To identify preoperative and intraoperative factors affecting breakthrough corneal haze incidence after photorefractive keratectomy (PRK) with mitomycin C (MMC). Methods: In this retrospective study of PRK performed at the Care Vision Refractive Laser Center, Tel Aviv, Israel, a total of 7535 eyes (n = 3854 patients; mean age ± SD, 26 ± 6 years; 55% men) underwent PRK with intraoperative MMC application. Patients with histories of corneal pathology or surgery were excluded. Incidence, time of onset, and corneal haze severity were documented on follow-up of 118 ± 110 days. Eyes were grouped by...
Source: Cornea - July 10, 2017 Category: Opthalmology Tags: Clinical Science Source Type: research

Cellular Therapy With Human Autologous Adipose-Derived Adult Stem Cells for Advanced Keratoconus
Conclusions: Cellular therapy of the human corneal stroma in vivo with autologous ADASCs appears to be safe. Stem cells survive in vivo with intrastromal new collagen production. Future studies with larger samples are required to confirm these preliminary results. (Source: Cornea)
Source: Cornea - July 10, 2017 Category: Opthalmology Tags: Clinical Science Source Type: research

Endothelial Cell Loss in Diabetic and Nondiabetic Eyes After Cataract Surgery
Conclusions: Diabetic patients demonstrated increased ECL when compared with nondiabetic patients after cataract surgery. However, the role of diabetic control in reducing ECL remains unclear. (Source: Cornea)
Source: Cornea - July 10, 2017 Category: Opthalmology Tags: Clinical Science Source Type: research

Validity of Postmortem Glycated Hemoglobin to Determine Status of Diabetes Mellitus in Corneal Donors
Conclusions: Postmortem HbA1c testing is feasible with current eye bank procedures and is reflective of glycemic control of donors during 90 days before death. HbA1c testing could potentially be a useful adjunct to review of the medical history and records for donor assessment for endothelial keratoplasty suitability and long-term graft success. (Source: Cornea)
Source: Cornea - July 10, 2017 Category: Opthalmology Tags: Clinical Science Source Type: research

Characterization of Corneal Involvement in Eyes With Mucous Membrane Pemphigoid by In Vivo Confocal Microscopy
Purpose: To describe the morphological features of the corneal epithelial layers, subbasal nerve plexus, stroma, and endothelium in patients with mucous membrane pemphigoid (MMP) as shown by in vivo confocal microscopy (IVCM). Methods: Central corneal images were captured from 10 healthy age-matched control eyes and 30 eyes with clinically diagnosed MMP by in vivo laser scanning confocal microscopy (HRT III RCM). Morphological changes of the corneal epithelial layers, stroma, and endothelium, characteristics of corneal nerves, and presence of inflammatory dendritic cells (DCs) were evaluated. Results: Images obtained by ...
Source: Cornea - July 10, 2017 Category: Opthalmology Tags: Clinical Science Source Type: research

Quantitative Analysis of Depth, Distribution, and Density of Cysts in Acanthamoeba Keratitis Using Confocal Microscopy
Conclusions: Eyes with AK requiring therapeutic keratoplasty were more likely to have a deeper and more diffuse penetration of cysts in the cornea compared with those resolving with medical treatment. (Source: Cornea)
Source: Cornea - July 10, 2017 Category: Opthalmology Tags: Clinical Science Source Type: research

Morphology and Function of Meibomian Glands and Other Tear Film Parameters in Junior High School Students
Purpose: We measured tear film parameters, including the morphology and function of meibomian glands, in junior high school students at 15 years of age. Methods: A total of 111 eyes of 111 students (56 males and 55 females) were enrolled in the study. The ocular symptom score (0–14), after-school study time, lipid layer thickness (LLT) of the tear film, partial blink rate, lid margin abnormalities (0–4), tear film breakup time, corneal and conjunctival epithelial damage (fluorescein staining score, 0–9), meiboscore as determined by noncontact meibography (0–6), Schirmer test value, and meibum grade...
Source: Cornea - July 10, 2017 Category: Opthalmology Tags: Clinical Science Source Type: research

Efficacy of 2-Month Treatment With Cord Blood Serum Eye Drops in Ocular Surface Disease: An In Vivo Confocal Microscopy Study
Purpose: To investigate the morphological changes of corneal epithelium and subbasal nerves by in vivo confocal microscopy in patients with ocular surface disease (OSD) treated with cord blood serum (CBS) eye drops. Methods: Twenty patients with OSD (mean age 61.1 ± 12.6 years) were included in this prospective 1-arm study and treated with CBS eye drops for 2 months. Corneal sensitivity, Schirmer test score, breakup time, subjective symptoms [Ocular Surface Disease Index (OSDI) and Visual Analogue Scale (VAS)], and corneal staining were evaluated before (T0) and after (T1) treatment. In vivo confocal microscopy ana...
Source: Cornea - July 10, 2017 Category: Opthalmology Tags: Clinical Science Source Type: research

Effects of Diquafosol Ophthalmic Solution on Quality of Life in Dry Eye Assessed Using the Dry Eye–Related Quality-of-Life Score Questionnaire: Effectiveness in Patients While Reading and Using Visual Display Terminals
Conclusions: Diquafosol ophthalmic solution was effective in patients with dry eye, especially those with foreign body sensation and problems when reading and using visual display terminals. (Source: Cornea)
Source: Cornea - July 10, 2017 Category: Opthalmology Tags: Clinical Science Source Type: research

Central Connections of the Lacrimal Functional Unit
Conclusions: The wetting length was reduced by topical anesthesia, when instilled bilaterally and ipsilaterally. The latter response implies an ipsilateral, reflex sensory drive to lacrimal secretion. In the unanesthetized fellow eye, the reduction compared with its saline control was not quite significant. This implies a relative lack of central, sensory, reflex cross-innervation, although the possibility cannot entirely be ruled out. These results are relevant to the possibility of reflex lacrimal compensation from a normal fellow eye, in cases of unilateral corneal anesthesia. (Source: Cornea)
Source: Cornea - July 10, 2017 Category: Opthalmology Tags: Clinical Science Source Type: research

Patients' Perceived Treatment Effectiveness in Dry Eye Disease
This study aimed to evaluate patients' PTE in dry eye disease (DED) and investigate factors contributing to these patients' perceptions. Methods: This cross-sectional study included 66 patients with DED. At enrollment, all patients had comprehensive ophthalmic assessment. In addition, to evaluate the patient's PTE, they were asked to use a 10-point scale ranging from “strongly disagree (score 1)” to “strongly agree (score 10)” to score their views on whether their DED treatments had been effective. Changes in clinical parameters of DED over time during their care were also evaluated retrospectively...
Source: Cornea - July 10, 2017 Category: Opthalmology Tags: Clinical Science Source Type: research

Femtosecond Laser Assisted Pterygium Surgery
Conclusions: FLAPS is a new technique, in which the preparation of an ultrathin CAG is done by the FSL. After optimization in porcine eyes, the clinical trial in the first 6 eyes was performed without any complications and the FSL might assist in further standardizing the surgical procedure. Longer follow-up and larger cohorts are needed to assess recurrence rates. (Source: Cornea)
Source: Cornea - June 13, 2017 Category: Opthalmology Tags: Techniques Source Type: research

New Technique of Femtosecond Laser-Assisted Intracorneal Ring Segment Implantation
Conclusions: The results of this pilot study are promising. A comparative prospective study with more eyes and longer follow-up may confirm whether this technique is better than the conventional femtosecond laser-assisted one. (Source: Cornea)
Source: Cornea - June 13, 2017 Category: Opthalmology Tags: Techniques Source Type: research

Microkeratome-Assisted Anterior Lamellar Keratoplasty for the Correction of High-Degree Postkeratoplasty Astigmatism
Conclusions: MALK is an effective and safe technique for the correction of high-degree postkeratoplasty astigmatism. (Source: Cornea)
Source: Cornea - June 13, 2017 Category: Opthalmology Tags: Techniques Source Type: research

Bilateral Herpetic Keratitis After Bilateral Intravitreal Bevacizumab for Exudative Macular Degeneration
Conclusions: To our knowledge, this is the first documented account of bilateral herpetic epithelial keratitis after bilateral intravitreal bevacizumab injections. (Source: Cornea)
Source: Cornea - June 13, 2017 Category: Opthalmology Tags: Case Report Source Type: research

Solitary Iris Plasmacytoma With Anterior Chamber Crystalline Deposits
Conclusions: Iris plasmacytoma is rare and should prompt systemic evaluation to rule out multiple myeloma. Solitary iris plasmacytoma can be successfully treated with plaque radiotherapy. (Source: Cornea)
Source: Cornea - June 13, 2017 Category: Opthalmology Tags: Case Report Source Type: research

Immunohistochemical Profiling of Corneas With Fuchs Endothelial Corneal Dystrophy
Purpose: Fuchs endothelial corneal dystrophy (FECD) is the leading indication for endothelial keratoplasty. Further insight into its pathophysiology is needed to develop alternative therapies. Methods: Sixteen genes from a previous microarray expression experiment (FECD vs. normal) were validated using immunohistochemistry on paraffin-embedded corneas (n = 6 FECD, n = 6 normal). The results were quantified manually and semiautomatically. Results: A higher percentage of corneal endothelial cells stained for alpha–smooth muscle actin (αSMA), cytokeratin 7, and superoxide dismutase 3 in FECD versus normal [odds ...
Source: Cornea - June 13, 2017 Category: Opthalmology Tags: Basic Investigation Source Type: research

Comparison of 2 Different Methods of Transepithelial Corneal Collagen Cross-Linking: Analysis of Corneal Histology and Hysteresis
Conclusions: Accelerated transepithelial CXL using pulsed UVA showed considerably deeper effect in the stroma with keratocyte loss than transepithelial CXL using continuous UVA. (Source: Cornea)
Source: Cornea - June 13, 2017 Category: Opthalmology Tags: Basic Investigation Source Type: research

Biomechanical and Histopathologic Effects of Pulsed-Light Accelerated Epithelium-On/-Off Corneal Collagen Cross-Linking
Conclusions: Both transepithelial and accelerated epithelium-off CXL produced biomechanical and histopathologic improvements, which were not significantly different between the 2 pulsed-light accelerated CXL treatments. (Source: Cornea)
Source: Cornea - June 13, 2017 Category: Opthalmology Tags: Basic Investigation Source Type: research