Oleander-Associated Keratitis and Uveitis
Conclusions:
Severe corneal edema and anterior uveitis can be associated with oleander exposure. Aggressive treatment with oral and topical steroids may be required without persistent sequelae at the 5-month follow-up. Ophthalmologists should consider this inflammatory reaction if patients experience ocular exposure to oleander. (Source: Cornea)
Source: Cornea - September 18, 2022 Category: Opthalmology Tags: Case Report Source Type: research
Initial Case Report of Cladorrhinum samala Mycotic Keratitis
Conclusions:
We report the first case of keratitis by C. samala, highlighting the emergence of a rare dematiaceous fungi causing keratitis and the role of molecular modalities in the diagnosis of nonsporulating fungi in suspected cases. (Source: Cornea)
Source: Cornea - September 18, 2022 Category: Opthalmology Tags: Case Report Source Type: research
Corneal Pigment Opacity From Face-Down Positioning After Pars Plana Vitrectomy, Treated With Descemet Stripping Only Technique
Discussion:
This is, to the best of our knowledge, the first case describing the formation of a corneal endothelial opacity because of retinal pigment epithelium deposition associated with face-down positioning after PPV for retinal detachment. DSO is a minimally invasive, viable alternative to endothelial keratoplasty or temporary keratoprosthesis placement for the clearance of focal corneal endothelial opacities for PPV. (Source: Cornea)
Source: Cornea - September 18, 2022 Category: Opthalmology Tags: Case Report Source Type: research
Long-Term Results of Postoperative Rescuing of Inverted DMEK Grafts: Two Case Reports
Conclusions:
Postoperative repositioning of an inverted DMEK graft may be a viable procedure to delay or prevent regrafting. (Source: Cornea)
Source: Cornea - September 18, 2022 Category: Opthalmology Tags: Case Report Source Type: research
Outcomes of Nontuberculous Mycobacterial Keratitis After Clear Corneal Incision Phacoemulsification Surgery: A Case Series of 6 Eyes in South Florida
Conclusions:
Prompt medical treatment with combined topical and oral therapy can lead to infection resolution and favorable visual recovery. Early surgical intervention can ensure good outcomes in cases of scleral extension. (Source: Cornea)
Source: Cornea - September 18, 2022 Category: Opthalmology Tags: Case Report Source Type: research
DescePrep Significantly Increases Descemet Membrane Endothelial Keratoplasty Processing Efficiency and Success Rate in Diabetic Human Donor Corneas in Comparison With Manual Dissection
Purpose:
The purpose of this study was to compare the safety, efficacy, and efficiency of a Descemet membrane endothelial keratoplasty (DMEK) graft processing device, DescePrep, with a manual dissection technique through the measurement of tissue yield, processing time, and graft viability in nondiabetic and diabetic donor corneas.
Methods:
Nondiabetic (n = 20) and diabetic (n = 20) donor corneas were processed using DescePrep, which standardizes the liquid bubble technique. Nondiabetic (n = 20) and diabetic (n = 24) donor corneas were also processed through manual dissection. Corneas were stained, processed, an...
Source: Cornea - September 18, 2022 Category: Opthalmology Tags: Basic Investigation Source Type: research
Examination of a Modified Graft Preparation Technique to Induce Double-Scroll Formation and Promote the Use of Younger Descemet Membrane Endothelial Keratoplasty Donor Tissue
Conclusions:
Double-scroll graft formation using controlled BSS bursts is a reliable technique that can be performed without causing additional damage to DMEK grafts. This technique may make graft unscrolling easier and can promote the use of younger donor tissue for DMEK. (Source: Cornea)
Source: Cornea - September 18, 2022 Category: Opthalmology Tags: Basic Investigation Source Type: research
Pegylated Interferon Alpha 2a for the Treatment of Ocular Surface Squamous Neoplasia
Conclusions:
Topical PegIFN-α-2a might be an effective and safe treatment option for noninvasive OSSN. (Source: Cornea)
Source: Cornea - September 18, 2022 Category: Opthalmology Tags: Basic Investigation Source Type: research
Investigation of SARS-CoV-2 in Postmortem Ocular Tissues and Evaluation of Its Effects on Corneal Donation
Conclusions:
Cadavers with negative postmortem nasopharyngeal swab samples for SARS-CoV-2 and those with the time from diagnosis to death of>3 weeks may be considered as candidates for corneal donation. (Source: Cornea)
Source: Cornea - September 18, 2022 Category: Opthalmology Tags: Clinical Science Source Type: research
Effect of Azithromycin on the Ocular Surface Microbiome of Children in a High Prevalence Trachoma Area
Conclusions:
We found a reduction in the load of C. trachomatis and 3 Neisseria species in communities treated with azithromycin. These benefits came at the cost of selection for macrolide resistance. (Source: Cornea)
Source: Cornea - September 18, 2022 Category: Opthalmology Tags: Clinical Science Source Type: research
Effects of Type 2 Diabetes Mellitus and Smoking on Changes in Corneal Endothelial Morphology and Cell Density
Purpose:
The purpose of this study was to compare the corneal endothelial morphology and cell density of diabetic smokers and nonsmokers with 50 to 70 age-matched healthy subjects and to determine whether smoking increases the effects of type 2 diabetes mellitus (DM) on these corneal parameters.
Methods:
This prospective cohort study included 200 patients who were assigned to 4 groups, including smokers with type 2 DM (group 1), nonsmokers with type 2 DM (group 2), healthy smokers (group 3), and healthy nonsmokers (control group, group 4). Noncontact specular microscopy was used to measure central endothelial ce...
Source: Cornea - September 18, 2022 Category: Opthalmology Tags: Clinical Science Source Type: research
Implementation of the Corneal Sweep Test in the Diagnosis of Recurrent Corneal Erosion: A 2-Year Retrospective Study
Conclusions:
The CST is a new and effective technique to help diagnose corneal erosions in the absence of visible corneal findings. Clear corneal cataract surgery is an under-recognized but important risk factor to consider because the incision can be the source for an erosion. Using the CST could lead to a paradigm shift in the way clinicians approach RCEs and patients with a persistent ocular pain syndrome. (Source: Cornea)
Source: Cornea - September 18, 2022 Category: Opthalmology Tags: Clinical Science Source Type: research
Prevalence and Characteristics of Dupilumab-Induced Ocular Surface Disease in Adults With Atopic Dermatitis
Conclusions:
DIOSD is a common adverse event that is usually mild but may lead to treatment interruption and vision-threatening complications. A personal history of asthma and family history of atopic dermatitis may be associated with a higher risk of developing DIOSD. (Source: Cornea)
Source: Cornea - September 18, 2022 Category: Opthalmology Tags: Clinical Science Source Type: research
Dysbiosis of Ocular Surface Microbiota in Patients With Refractive Allergic Conjunctival Diseases
Conclusions:
The ocular surface microbiota in patients with severe ACD exhibited decreased diversity and exacerbation of dysbiosis compared with that in patients with mild ACD and control subjects. Patients with mild refractory ACD also exhibited decreased diversity of these microbiota. These alterations in microbiota indicated a change in the ocular surface of patients with refractory ACD (be it because of disease pathogenesis or topical immunomodulatory treatment). (Source: Cornea)
Source: Cornea - September 18, 2022 Category: Opthalmology Tags: Clinical Science Source Type: research
Considerations for Corneal Surgery With Patients in the 10th Decade of Life
Purpose:
The purpose of this study was to report the indications, ocular and systemic comorbidities, and surgical outcomes of corneal transplantation in patients older than 90 years.
Methods:
A retrospective review was conducted to identify individuals 90 years and older who underwent corneal transplantation surgery at the Bascom Palmer Eye Institute between January 2013 and October 2020. Outcomes included best-corrected visual acuity and graft survival over time. Paired t tests were used to compare visual acuity preoperatively versus postoperatively. Graft survival was evaluated with Kaplan–Meier curves.
R...
Source: Cornea - September 18, 2022 Category: Opthalmology Tags: Clinical Science Source Type: research
