Factors Influencing Corneal Biomechanics in Diabetes Mellitus
Purpose: Diabetes mellitus (DM) induces changes in corneal biomechanical properties. The influence of disease-specific factors was evaluated, and a novel DM index was created. Methods: Eighty-one patients with DM and 75 healthy subjects were matched according to age, intraocular pressure, and central corneal thickness. Information on the disease was collected, and measurements with the Ocular Response Analyzer and the Corvis ST were taken. Results were compared between the groups, and the influence of disease-specific factors was evaluated. From dynamic corneal response parameters, a DM index was calculated. Results:...
Source: Cornea - April 2, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

Corneal Collagen Cross-Linking Under General Anesthesia for Pediatric Patients With Keratoconus and Developmental Delay
Conclusions: We demonstrate the efficacy and safety of CXL under general anesthesia in halting the progression of KCN for pediatric patients with developmental delay or an inability to cooperate with the procedure until topical anesthesia. (Source: Cornea)
Source: Cornea - April 2, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

Correlation Between Angle Parameters and Central Corneal Thickness in Fuchs Endothelial Corneal Dystrophy
Purpose: To evaluate the correlation between anterior chamber parameters and central corneal thickness (CCT) or peripheral corneal thickness (PCT) in patients with Fuchs endothelial corneal dystrophy (FECD) using anterior segment optical coherence tomography. Methods: This case–control study included 20 eyes from 20 patients with FECD and 31 eyes from 31 patients with healthy corneas. CCT was measured as an indicator of FECD severity. Anterior chamber angle parameters, including trabecular–iris angle (TIA500) and angle opening distance (AOD500), were measured as an indicator of peripheral anterior chamber ...
Source: Cornea - April 2, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

Long-term Results of Corneal Wedge Resection for High Postkeratoplasty Astigmatism
Conclusions: Corneal wedge resection is a valuable resource for the management of high postkeratoplasty astigmatism. It is a safe and reproducible procedure, with stable results at 12 months and thereafter. (Source: Cornea)
Source: Cornea - April 2, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

Reply
No abstract available (Source: Cornea)
Source: Cornea - March 12, 2020 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Comment on: “In Vivo Confocal Microscopy of Prominent Conjunctival and Corneal Nerves in Multiple Endocrine Neoplasia Type 2B”
No abstract available (Source: Cornea)
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Comment on “Interferon Alpha-2b Eye Drops Prevent Recurrence of Pterygium After the Bare Scleral Technique: A Single-Center, Sequential, and Controlled Study”
No abstract available (Source: Cornea)
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Comment on: “Interferon Alpha-2b Eye Drops Prevent Recurrence of Pterygium After the Bare Sclera Technique: A Single-Center, Sequential, and Controlled Study”
No abstract available (Source: Cornea)
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Reply
No abstract available (Source: Cornea)
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Obstructive Sleep Apnea–Hypopnea Syndrome and Keratoconus: An Epiphenomenon Related to Sleep Position?
No abstract available (Source: Cornea)
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Current Global Bioethical Dilemmas in Corneal Transplantation
Conclusions: Around the world, the number of required corneal transplants exceeds the number of donated corneas that are available and suitable for transplantation. This shortage of corneal tissue has led to the emergence of practices that may put the 4 basic principles of bioethics at risk: autonomy, beneficence, nonmaleficence, and justice. Therefore, it has been necessary to create ethical guidelines such as the Barcelona Principles and the World Health Organization Principles of Transplantation that attempt to regulate these practices. (Source: Cornea)
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Review Source Type: research

Four-Flanged Intrascleral Intraocular Lens Fixation Technique: No Flaps, No Knots, No Glue
Conclusions: The 4-flanged technique improves and simplifies the existing single-piece, nonfoldable IOL intrascleral fixation techniques. (Source: Cornea)
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Techniques Source Type: research

Clinical Evaluation of the “Lifeline Suture” Technique for DSAEK in Cases Without Posterior Capsule Using a Novel Donor Insertion Device
Conclusions: In this preliminary case series of bullous keratopathy without posterior capsule, DSAEK outcomes using the novel NSI donor inserter with lifeline suture were comparable or better than the results expected with conventional strategies. Thus, this technique enabled apparently safe DSAEK, preventing donor migration into the vitreous cavity while maintaining a stable anterior chamber, and is suitable for complex eyes including aphakia, lacking posterior capsule, or avitreal. (Source: Cornea)
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Techniques Source Type: research

Adenocarcinoma Arising in the Conjunctiva With Periparotid Lymph Node Metastases
Conclusions: ADC arising in the conjunctiva is a very rare occurrence. Additional observation is required for the management of this rare conjunctival tumor. (Source: Cornea)
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Case Report Source Type: research

Treatment Outcome of Modified Argon Laser Photoablation for Conjunctival Cysts
Conclusions: Our modified method of argon laser photoablation uses staining of the conjunctival cyst surface to increase the amount of thermal laser energy absorbed by the target. This novel technique is simple and effective for treating conjunctival cysts in an outpatient clinic. (Source: Cornea)
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Basic Investigation Source Type: research

Protective Effects of Cyclosporine A Emulsion Versus Cyclosporine A Cationic Emulsion Against Desiccation Stress in Human Corneal Epithelial Cells
Conclusions: CsACE had more potent anti-inflammatory and antiapoptotic effects than CsAE in a transwell desiccation stress model. CsACE also enhanced proliferation and survival factors under desiccation stress compared with CsAE in this in vitro dry eye model. (Source: Cornea)
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Basic Investigation Source Type: research

Comparing Dry Eye Disease After Small Incision Lenticule Extraction and Laser Subepithelial Keratomileusis
Conclusions: Both SMILE and LASEK groups showed temporary decreases in corneal sensitivity, which recovered to baseline levels. Although subjective symptoms worsened after SMILE, SIT values improved after LASEK. Compared with SMILE, LASEK yielded better results regarding subjective symptoms, tear production, and corneal sensitivity. (Source: Cornea)
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

Discrepancies in Endothelial Cell Density Values of Human Donor Corneas Resulting From Comparison Between Specular Microscopes and Endothelial Analysis Methods
Conclusions: There is a slight statistically significant mean difference between the ECD values obtained from the 2 specular microscopes, which is negated by standardization to a single analysis method. Eye banks and surgeons should use caution in making decisions based only on very small differences in ECD between otherwise equivalent corneal donor tissues. (Source: Cornea)
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

An Analysis of YouTube Videos as Educational Resources for Patients About Refractive Surgery
Conclusions: Although some of the analyzed online videos contain beneficial information, YouTube videos do not generally seem to be useful as educational resources for patients about refractive surgery. Nevertheless, health care professionals should continue to assess the reliability and usefulness of medical information provided by online resources from the viewpoint of patients. (Source: Cornea)
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

Design and Outcomes of a Novel Keratoprosthesis: Addressing Unmet Needs in End-Stage Cicatricial Corneal Blindness
Conclusions: The Lux keratoprosthesis was developed for patients with severe cicatricial keratoconjunctivitis who were otherwise not candidates for existing keratoprosthesis designs. Short-term outcomes after implantation of the Lux keratoprosthesis were encouraging. (Source: Cornea)
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

Efficacy of Amniotic Membrane Transplantation for the Treatment of Corneal Ulcers
Purpose: To evaluate the outcome of amniotic membrane transplantation (AMTX) as a treatment for corneal ulcers. Methods: Patients treated with AMTX for refractory corneal ulcers between 2012 and 2017 were evaluated in a retrospective analysis. Primary outcome measure was complete reepithelialization. Results: A total of 149 patients were included (mean age 68 ± 18 years). The mean duration between ulcer onset and AMTX was 42 ± 46 days. The longest time between ulcer diagnosis and AMTX was found in bacterial ulcers and the shortest time to AMTX in eyes with trauma/chemical burns (mean 65 ± 15 da...
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

Eyeliner Induces Tear Film Instability and Meibomian Gland Dysfunction
Purpose: To compare the degree of tear film instability and severity of meibomian gland dysfunction between subjects who use eyeliner and those who do not use eyeliner. Methods: This cross-sectional study included 42 healthy volunteer women who had no dry eye symptoms (Ocular Surface Disease Index score (Source: Cornea)
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

FemtoLASIK After Descemet Membrane Endothelial Keratoplasty
Conclusions: Our findings suggest that the residual refractive error after DMEK surgery can be safely and effectively treated with FemtoLASIK. (Source: Cornea)
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

A Combined Biomechanical and Tomographic Model for Identifying Cases of Subclinical Keratoconus
Purpose: To develop a combined biomechanical and tomographic model for identifying eyes with subclinical keratoconus (SKC) that are categorized as normal or borderline in the Pentacam Belin/Ambrósio Enhanced Ectasia Display. Methods: This case–control study comprised 62 eyes with SKC and randomly selected eyes of 186 age-matched healthy controls. SKC was defined as the presence of the following: 1) normal topography, topometric indices, and slit lamp; 2) normal or borderline Belin/Ambrósio Enhanced Ectasia Display D index, back and front elevation difference; and 3) keratoconus in the fellow eye. S...
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

Long-Term Outcomes of Descemet Membrane Endothelial Keratoplasty in Postvitrectomized Eyes With the Use of Pars Plana Infusion
Conclusions: Although pars plana infusion is a helpful technique for DMEK in vitrectomized eyes, such cases are still quite difficult to perform compared with standard DMEK and use of an infusion may increase the risk of retinal complications. Descemet Stripping Automated Endothelial Keratoplasty may be the preferred technique in these challenging vitrectomized eyes. (Source: Cornea)
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

The Impact on Work Patterns of Implementing the Save Sight Keratoconus Registry in the Hospital Setting
Conclusions: The SSKR was implemented into clinical practice without affecting the total consultation time, time spent directly interacting with patients, or use of patient records. Our findings support that registries requiring data entry could be widely adopted into routine clinical practice. (Source: Cornea)
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

Re-Treatment by Flap Relift Versus Surface Ablation After Myopic Laser In Situ Keratomileusis
Purpose: To compare clinical outcomes of patients undergoing first re-treatment by flap relift with those re-treated by surface ablation on the flap after an initial myopic laser-assisted in situ keratomileusis (LASIK) procedure. Methods: This is a retrospective cohort analysis of consecutive patients who underwent myopic LASIK and required re-treatment between January 2007 and December 2016. Cases re-treated by flap relift were propensity score matched with cases re-treated by surface ablation, and clinical outcomes were compared. One eye from each patient was included. Results: A total of 1,234 out of 21,191 case...
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

Clinical Outcomes and Endothelial Cell Density After Descemet Membrane Endothelial Keratoplasty Using Peripherally-trephinated Donor Tissue (DMEK-pD) in Fuchs Endothelial Corneal Dystrophy
Purpose: To evaluate the clinical outcomes and endothelial cell density (ECD) after Descemet membrane endothelial keratoplasty using peripherally trephinated donor tissue (DMEK-pD) and compare with DMEK using centrally trephinated donor tissue (DMEK-cD) in patients with Fuchs endothelial corneal dystrophy (FECD). Methods: This was a prospective comparative interventional case series. One hundred twenty-five eyes of 110 patients with FECD and cataract who underwent either DMEK-pD (n = 60) or DMEK-cD (n = 65) combined with phacoemulsification, between June 2016 and November 2018, were included. Preoperative and postoper...
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

Corneal Topographic Astigmatism Based on Total Corneal Power Data (CorT Total): A Benchmark for Total Corneal Astigmatism
Conclusions: The CorT Total is a reliable benchmark measure that can be used to assess how well other measures of total corneal astigmatism correspond with the manifest refractive cylinder. (Source: Cornea)
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

Cost–Benefit and Cost–Utility Analysis of Amphotericin B Supplementation of Corneal Storage Media With Endothelial Keratoplasty-Prepared Tissue
Conclusions: We found that amphotericin B supplementation can be cost-effective under conservative assumptions if it is moderately effective in preventing post-EK fungal infections. (Source: Cornea)
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

Outcomes of Gel Stent Implantation for Glaucoma in Patients With Previous Corneal Graft Surgery: A Case Series
Conclusions: Glaucoma after graft surgery is a well-known and devastating complication, and as numbers of graft surgery performed increases, so will the incidence of glaucoma. MIGS devices such as the Xen45 Gel Stent (Allergan plc) should become a part of our accepted armory to treat raised IOP refractory to medical treatment without delay. (Source: Cornea)
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

Double-Masked and Unmasked Prospective Study of Terpinen-4-ol Lid Scrubs With Microblepharoexfoliation for the Treatment of Demodex Blepharitis
Purpose: To evaluate terpinen-4-ol lid scrubs (Cliradex) with Microblepharoexfoliation (MBE) (BlephEx) in the treatment of Demodex blepharitis. Methods: An Institutional Review Board (IRB) approved the randomized prospective double-masked trial of 50 patients with Demodex positive blepharitis. All subjects were given an in-office MBE treatment and randomized to masked lid scrubs (terpinen-4-ol or sham) twice daily for 1 month. All subjects then returned for an additional MBE treatment and received open-label terpinen-4-ol scrubs twice daily for 1 month. Outcomes: Demodex levels, Ocular Surface Disease Index, tear o...
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

A 6-Week, Prospective, Randomized, Single-Masked Study of Lifitegrast Ophthalmic Solution 5% Versus Thermal Pulsation Procedure for Treatment of Inflammatory Meibomian Gland Dysfunction
Conclusions: Although MGD is often considered a disease of gland obstruction, these findings demonstrate antiinflammatory treatment with lifitegrast significantly improved patient symptoms and signs compared with treatment for obstruction (TPP). Lifitegrast should be included in treatment for inflammatory MGD. (Source: Cornea)
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

Risk Factors for the Development of Ocular Hypertension After Keratoplasty: A Systematic Review
Purpose: To identify risk factors for the development of ocular hypertension after keratoplasty. Methods: A systematic search in PubMed and Embase identified 67 relevant articles published between January 1990 and 2019. We preferentially searched for data on an intraocular pressure increase above 21 mmHg at 6 months or a threshold or time point close to that and reported whether the preoperative or intraoperative status of risk factors was defined. The results were presented in evidence tables, visualizing the direction of the association, whether univariate and/or multivariate analysis was performed, and the signific...
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Review Source Type: research

Measurement of Quality of Life in Keratoconus
Conclusions: There is a need for a comprehensive and high-quality patient-reported outcome measure in keratoconus. A questionnaire should be chosen based on the purpose and the quality of the questionnaire. This review guides selection of an appropriate questionnaire. (Source: Cornea)
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Review Source Type: research

Femtosecond Laser-Assisted Penetrating Keratoplasty for Treating Infective Keratitis
Conclusions: Femtosecond laser-assisted PKP was found to be an effective method for treating infective keratitis (particularly that caused by Pseudomonas aeruginosa and Fusarium) that did not respond to medical treatment. Early surgical intervention before the disease becomes advanced is recommended. (Source: Cornea)
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Techniques Source Type: research

Descemet Stripping Only for a Chronic Descemet Detachment After Cataract Surgery
Conclusions: DSO is a viable therapy in certain cases of postsurgical corneal decompensation. (Source: Cornea)
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Case Report Source Type: research

Suprachoroidal Hemorrhage During Descemet Membrane Endothelial Keratoplasty
Conclusions: Suprachoroidal hemorrhage is a rare but potentially devastating intraoperative complication which may occur during DMEK, particularly in eyes with relevant risk factors. An inability to deepen the anterior chamber following graft implantation may signify the condition. (Source: Cornea)
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Case Report Source Type: research

Corneal Cryopreservation Using Glycerylphosphorylcholine-Enriched Medium
Conclusions: This study demonstrates a cryoprotective effect of corneas preserved in K-Sol containing the phosphodiester GPC at subzero-degree temperatures. In corneas immersed in preservation medium containing GPC, a higher degree of transparency is maintained and a lesser degree of histopathologic changes is observed with storage at both −8°C and in liquid nitrogen. (Source: Cornea)
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Basic Investigation Source Type: research

A Fixed-Depth Microneedle Enhances Reproducibility and Safety for Corneal Gene Therapy
Conclusions: Further development of the PCI microneedle is warranted especially for AAV corneal gene therapy and offers the potential to enhance transduction while significantly reducing safety concerns and intraclinician and interclinician injection variability. (Source: Cornea)
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Basic Investigation Source Type: research

Quantitative and Qualitative Differences in Endothelial Cell Loss Between Endothelium-In Versus Endothelium-Out Loading in Descemet Membrane Endothelial Keratoplasty
Conclusions: Our results suggest comparable ECL between Geuder (endothelium-out) and Coronet (endothelium-in) DMEK EndoGlide tissue injection techniques. Patterns of ECL in the Coronet group correlated with forceps grabs, but this study suggests that additional manipulation of tissue does not result in higher ECL. (Source: Cornea)
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Basic Investigation Source Type: research

Coexistence of Congenital Hereditary Endothelial Dystrophy and Fuchs Endothelial Corneal Dystrophy Associated With SLC4A11 Mutations in Affected Families
Conclusions: Heterozygosity for SLC4A11 mutations in the parents of children with autosomal recessive CHED appears to be a risk factor for the development of FECD in these cases. (Source: Cornea)
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Basic Investigation Source Type: research

Epidemiological Association Between Systemic Diseases and Keratoconus in a Korean Population: A 10-Year Nationwide Cohort Study
Purpose: To investigate the association of systemic diseases with keratoconus in the general Korean population. Methods: This is a nationwide population-based retrospective cohort study using the Korean National Health Insurance Service-National Sample Cohort database from 2002 to 2015, involving 1,108,369 individuals. Patients with keratoconus were identified using the Korean standard classification of diseases code H18.6. The prevalence and annual incidence rates were estimated. To examine the risk factors, 5 controls were matched per patient with keratoconus by propensity score matching using age and household inco...
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Basic Investigation Source Type: research

Multiple-Image Deep Learning Analysis for Neuropathy Detection in Corneal Nerve Images
Conclusions: The proposed method provides a completely automated analysis of corneal confocal images. Results demonstrate the potentiality of the CNN in identifying clinically useful features for corneal nerves by analysis of multiple images. (Source: Cornea)
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Basic Investigation Source Type: research

Histological Corneal Alterations in Keratoconus After Crosslinking—Expansion of Findings
Conclusions: CXL may cause permanent keratocyte loss or repopulation of altered keratocytes, resulting in clinical complications such as corneal opacification or perforation. Despite its good safety profile and high effectiveness in progressive keratoconus, CXL should be performed in accordance with current guidelines strictly adhering to protocol and safety standards. (Source: Cornea)
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Basic Investigation Source Type: research

Efficacy and Safety of Intense Pulsed Light in Patients With Meibomian Gland Dysfunction—A Randomized, Double-Masked, Sham-Controlled Clinical Trial
Purpose: To study the efficacy and safety of intense pulsed light (IPL) in patients with meibomian gland dysfunction (MGD). Methods: This prospective randomized double-masked sham-controlled trial included 114 patients with MGD. Patients were randomized into the IPL or sham group. Either the IPL or sham procedure was performed on days 0, 15, and 45. Ocular Surface Disease Index (OSDI), visual analog scale, visual acuity, tear breakup time, meibum quality and expressibility, meibography grade, ocular surface staining, tear film lipid layer thickness, tear osmolarity, Schirmer test, tear interleukin-1 receptor agonist, ...
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

The Role of Topical Azithromycin in the Treatment of Meibomian Gland Dysfunction
This study evaluates the efficacy of topical AZ supplementation to systemic AZ, warm compresses, artificial tears, and lid scrubs for the treatment of meibomian gland dysfunction (MGD). Methods: Eighty-five patients with stage 4 MGD were enrolled in the study. The patients enrolled into the study were divided into 2 groups. Group 1 comprised 55 patients who received preservative-free topical 1.5% AZ administered as a unit dose, and group 2 comprised 30 patients who did not receive topical AZ. Both groups were prescribed artificial tear eye drops and systemic AZ. Fluorescein tear film breakup time (TBUT), corneal stainin...
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

Comparison of Laser Platform Estimation and Objective Measurement of Maximum Ablation Depth Using Scheimpflug Pachymetry in Myopic Femtosecond Laser In Situ Keratomileusis
Purpose: To compare the preoperative estimation of maximum ablation depth provided by the laser platform with objective measurement using Scheimpflug pachymetry in myopic femtosecond laser-assisted in situ keratomileusis (FS-LASIK). Methods: This is a prospective study carried out at the Rothschild Foundation, Paris, France. In 89 consecutive myopic eyes (45 patients) treated with FS-LASIK, the maximum ablation depth was calculated by measuring the difference between preoperative and 3-month postoperative measurements in central corneal thickness using Scheimpflug pachymetry (Pentacam HR; Oculus Optikgeräte, Wetz...
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

Association Between Early Sjögren Markers and Symptoms and Signs of Dry Eye
Conclusions: Most of the individuals with DE tested positive for 1 or more EMS antibodies, including men and Hispanics. Future studies will be needed to understand how to incorporate EMS data into the care of an individual with DE. (Source: Cornea)
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

Psychometric Properties of the Keratoconus Outcomes Research Questionnaire: A Save Sight Keratoconus Registry Study
Purpose: The aim of this study was to evaluate the psychometric properties of the Keratoconus Outcomes Research Questionnaire (KORQ) in patients enrolled in the Save Sight Keratoconus Registry. Methods: A cross-sectional study was conducted utilizing prospectively collected web-based registry data. The psychometric properties of the KORQ were assessed using both classical test theory and Rasch analysis. Andrich group rating scale variant of the Rasch analysis was conducted using Winsteps software, Version 3.92.1. Results: The KORQ was completed by 189 patients with keratoconus (men, 67.7%; white, 69.8%; median age ...
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research