Eyeliner Induces Tear Film Instability and Meibomian Gland Dysfunction
Purpose: To compare the degree of tear film instability and severity of meibomian gland dysfunction between subjects who use eyeliner and those who do not use eyeliner. Methods: This cross-sectional study included 42 healthy volunteer women who had no dry eye symptoms (Ocular Surface Disease Index score (Source: Cornea)
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

FemtoLASIK After Descemet Membrane Endothelial Keratoplasty
Conclusions: Our findings suggest that the residual refractive error after DMEK surgery can be safely and effectively treated with FemtoLASIK. (Source: Cornea)
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

A Combined Biomechanical and Tomographic Model for Identifying Cases of Subclinical Keratoconus
Purpose: To develop a combined biomechanical and tomographic model for identifying eyes with subclinical keratoconus (SKC) that are categorized as normal or borderline in the Pentacam Belin/Ambrósio Enhanced Ectasia Display. Methods: This case–control study comprised 62 eyes with SKC and randomly selected eyes of 186 age-matched healthy controls. SKC was defined as the presence of the following: 1) normal topography, topometric indices, and slit lamp; 2) normal or borderline Belin/Ambrósio Enhanced Ectasia Display D index, back and front elevation difference; and 3) keratoconus in the fellow eye. S...
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

Long-Term Outcomes of Descemet Membrane Endothelial Keratoplasty in Postvitrectomized Eyes With the Use of Pars Plana Infusion
Conclusions: Although pars plana infusion is a helpful technique for DMEK in vitrectomized eyes, such cases are still quite difficult to perform compared with standard DMEK and use of an infusion may increase the risk of retinal complications. Descemet Stripping Automated Endothelial Keratoplasty may be the preferred technique in these challenging vitrectomized eyes. (Source: Cornea)
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

The Impact on Work Patterns of Implementing the Save Sight Keratoconus Registry in the Hospital Setting
Conclusions: The SSKR was implemented into clinical practice without affecting the total consultation time, time spent directly interacting with patients, or use of patient records. Our findings support that registries requiring data entry could be widely adopted into routine clinical practice. (Source: Cornea)
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

Re-Treatment by Flap Relift Versus Surface Ablation After Myopic Laser In Situ Keratomileusis
Purpose: To compare clinical outcomes of patients undergoing first re-treatment by flap relift with those re-treated by surface ablation on the flap after an initial myopic laser-assisted in situ keratomileusis (LASIK) procedure. Methods: This is a retrospective cohort analysis of consecutive patients who underwent myopic LASIK and required re-treatment between January 2007 and December 2016. Cases re-treated by flap relift were propensity score matched with cases re-treated by surface ablation, and clinical outcomes were compared. One eye from each patient was included. Results: A total of 1,234 out of 21,191 case...
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

Clinical Outcomes and Endothelial Cell Density After Descemet Membrane Endothelial Keratoplasty Using Peripherally-trephinated Donor Tissue (DMEK-pD) in Fuchs Endothelial Corneal Dystrophy
Purpose: To evaluate the clinical outcomes and endothelial cell density (ECD) after Descemet membrane endothelial keratoplasty using peripherally trephinated donor tissue (DMEK-pD) and compare with DMEK using centrally trephinated donor tissue (DMEK-cD) in patients with Fuchs endothelial corneal dystrophy (FECD). Methods: This was a prospective comparative interventional case series. One hundred twenty-five eyes of 110 patients with FECD and cataract who underwent either DMEK-pD (n = 60) or DMEK-cD (n = 65) combined with phacoemulsification, between June 2016 and November 2018, were included. Preoperative and postoper...
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

Corneal Topographic Astigmatism Based on Total Corneal Power Data (CorT Total): A Benchmark for Total Corneal Astigmatism
Conclusions: The CorT Total is a reliable benchmark measure that can be used to assess how well other measures of total corneal astigmatism correspond with the manifest refractive cylinder. (Source: Cornea)
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

Cost–Benefit and Cost–Utility Analysis of Amphotericin B Supplementation of Corneal Storage Media With Endothelial Keratoplasty-Prepared Tissue
Conclusions: We found that amphotericin B supplementation can be cost-effective under conservative assumptions if it is moderately effective in preventing post-EK fungal infections. (Source: Cornea)
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

Outcomes of Gel Stent Implantation for Glaucoma in Patients With Previous Corneal Graft Surgery: A Case Series
Conclusions: Glaucoma after graft surgery is a well-known and devastating complication, and as numbers of graft surgery performed increases, so will the incidence of glaucoma. MIGS devices such as the Xen45 Gel Stent (Allergan plc) should become a part of our accepted armory to treat raised IOP refractory to medical treatment without delay. (Source: Cornea)
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

Double-Masked and Unmasked Prospective Study of Terpinen-4-ol Lid Scrubs With Microblepharoexfoliation for the Treatment of Demodex Blepharitis
Purpose: To evaluate terpinen-4-ol lid scrubs (Cliradex) with Microblepharoexfoliation (MBE) (BlephEx) in the treatment of Demodex blepharitis. Methods: An Institutional Review Board (IRB) approved the randomized prospective double-masked trial of 50 patients with Demodex positive blepharitis. All subjects were given an in-office MBE treatment and randomized to masked lid scrubs (terpinen-4-ol or sham) twice daily for 1 month. All subjects then returned for an additional MBE treatment and received open-label terpinen-4-ol scrubs twice daily for 1 month. Outcomes: Demodex levels, Ocular Surface Disease Index, tear o...
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

A 6-Week, Prospective, Randomized, Single-Masked Study of Lifitegrast Ophthalmic Solution 5% Versus Thermal Pulsation Procedure for Treatment of Inflammatory Meibomian Gland Dysfunction
Conclusions: Although MGD is often considered a disease of gland obstruction, these findings demonstrate antiinflammatory treatment with lifitegrast significantly improved patient symptoms and signs compared with treatment for obstruction (TPP). Lifitegrast should be included in treatment for inflammatory MGD. (Source: Cornea)
Source: Cornea - March 7, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

Risk Factors for the Development of Ocular Hypertension After Keratoplasty: A Systematic Review
Purpose: To identify risk factors for the development of ocular hypertension after keratoplasty. Methods: A systematic search in PubMed and Embase identified 67 relevant articles published between January 1990 and 2019. We preferentially searched for data on an intraocular pressure increase above 21 mmHg at 6 months or a threshold or time point close to that and reported whether the preoperative or intraoperative status of risk factors was defined. The results were presented in evidence tables, visualizing the direction of the association, whether univariate and/or multivariate analysis was performed, and the signific...
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Review Source Type: research

Measurement of Quality of Life in Keratoconus
Conclusions: There is a need for a comprehensive and high-quality patient-reported outcome measure in keratoconus. A questionnaire should be chosen based on the purpose and the quality of the questionnaire. This review guides selection of an appropriate questionnaire. (Source: Cornea)
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Review Source Type: research

Femtosecond Laser-Assisted Penetrating Keratoplasty for Treating Infective Keratitis
Conclusions: Femtosecond laser-assisted PKP was found to be an effective method for treating infective keratitis (particularly that caused by Pseudomonas aeruginosa and Fusarium) that did not respond to medical treatment. Early surgical intervention before the disease becomes advanced is recommended. (Source: Cornea)
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Techniques Source Type: research

Descemet Stripping Only for a Chronic Descemet Detachment After Cataract Surgery
Conclusions: DSO is a viable therapy in certain cases of postsurgical corneal decompensation. (Source: Cornea)
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Case Report Source Type: research

Suprachoroidal Hemorrhage During Descemet Membrane Endothelial Keratoplasty
Conclusions: Suprachoroidal hemorrhage is a rare but potentially devastating intraoperative complication which may occur during DMEK, particularly in eyes with relevant risk factors. An inability to deepen the anterior chamber following graft implantation may signify the condition. (Source: Cornea)
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Case Report Source Type: research

Corneal Cryopreservation Using Glycerylphosphorylcholine-Enriched Medium
Conclusions: This study demonstrates a cryoprotective effect of corneas preserved in K-Sol containing the phosphodiester GPC at subzero-degree temperatures. In corneas immersed in preservation medium containing GPC, a higher degree of transparency is maintained and a lesser degree of histopathologic changes is observed with storage at both −8°C and in liquid nitrogen. (Source: Cornea)
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Basic Investigation Source Type: research

A Fixed-Depth Microneedle Enhances Reproducibility and Safety for Corneal Gene Therapy
Conclusions: Further development of the PCI microneedle is warranted especially for AAV corneal gene therapy and offers the potential to enhance transduction while significantly reducing safety concerns and intraclinician and interclinician injection variability. (Source: Cornea)
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Basic Investigation Source Type: research

Quantitative and Qualitative Differences in Endothelial Cell Loss Between Endothelium-In Versus Endothelium-Out Loading in Descemet Membrane Endothelial Keratoplasty
Conclusions: Our results suggest comparable ECL between Geuder (endothelium-out) and Coronet (endothelium-in) DMEK EndoGlide tissue injection techniques. Patterns of ECL in the Coronet group correlated with forceps grabs, but this study suggests that additional manipulation of tissue does not result in higher ECL. (Source: Cornea)
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Basic Investigation Source Type: research

Coexistence of Congenital Hereditary Endothelial Dystrophy and Fuchs Endothelial Corneal Dystrophy Associated With SLC4A11 Mutations in Affected Families
Conclusions: Heterozygosity for SLC4A11 mutations in the parents of children with autosomal recessive CHED appears to be a risk factor for the development of FECD in these cases. (Source: Cornea)
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Basic Investigation Source Type: research

Epidemiological Association Between Systemic Diseases and Keratoconus in a Korean Population: A 10-Year Nationwide Cohort Study
Purpose: To investigate the association of systemic diseases with keratoconus in the general Korean population. Methods: This is a nationwide population-based retrospective cohort study using the Korean National Health Insurance Service-National Sample Cohort database from 2002 to 2015, involving 1,108,369 individuals. Patients with keratoconus were identified using the Korean standard classification of diseases code H18.6. The prevalence and annual incidence rates were estimated. To examine the risk factors, 5 controls were matched per patient with keratoconus by propensity score matching using age and household inco...
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Basic Investigation Source Type: research

Multiple-Image Deep Learning Analysis for Neuropathy Detection in Corneal Nerve Images
Conclusions: The proposed method provides a completely automated analysis of corneal confocal images. Results demonstrate the potentiality of the CNN in identifying clinically useful features for corneal nerves by analysis of multiple images. (Source: Cornea)
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Basic Investigation Source Type: research

Histological Corneal Alterations in Keratoconus After Crosslinking—Expansion of Findings
Conclusions: CXL may cause permanent keratocyte loss or repopulation of altered keratocytes, resulting in clinical complications such as corneal opacification or perforation. Despite its good safety profile and high effectiveness in progressive keratoconus, CXL should be performed in accordance with current guidelines strictly adhering to protocol and safety standards. (Source: Cornea)
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Basic Investigation Source Type: research

Efficacy and Safety of Intense Pulsed Light in Patients With Meibomian Gland Dysfunction—A Randomized, Double-Masked, Sham-Controlled Clinical Trial
Purpose: To study the efficacy and safety of intense pulsed light (IPL) in patients with meibomian gland dysfunction (MGD). Methods: This prospective randomized double-masked sham-controlled trial included 114 patients with MGD. Patients were randomized into the IPL or sham group. Either the IPL or sham procedure was performed on days 0, 15, and 45. Ocular Surface Disease Index (OSDI), visual analog scale, visual acuity, tear breakup time, meibum quality and expressibility, meibography grade, ocular surface staining, tear film lipid layer thickness, tear osmolarity, Schirmer test, tear interleukin-1 receptor agonist, ...
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

The Role of Topical Azithromycin in the Treatment of Meibomian Gland Dysfunction
This study evaluates the efficacy of topical AZ supplementation to systemic AZ, warm compresses, artificial tears, and lid scrubs for the treatment of meibomian gland dysfunction (MGD). Methods: Eighty-five patients with stage 4 MGD were enrolled in the study. The patients enrolled into the study were divided into 2 groups. Group 1 comprised 55 patients who received preservative-free topical 1.5% AZ administered as a unit dose, and group 2 comprised 30 patients who did not receive topical AZ. Both groups were prescribed artificial tear eye drops and systemic AZ. Fluorescein tear film breakup time (TBUT), corneal stainin...
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

Comparison of Laser Platform Estimation and Objective Measurement of Maximum Ablation Depth Using Scheimpflug Pachymetry in Myopic Femtosecond Laser In Situ Keratomileusis
Purpose: To compare the preoperative estimation of maximum ablation depth provided by the laser platform with objective measurement using Scheimpflug pachymetry in myopic femtosecond laser-assisted in situ keratomileusis (FS-LASIK). Methods: This is a prospective study carried out at the Rothschild Foundation, Paris, France. In 89 consecutive myopic eyes (45 patients) treated with FS-LASIK, the maximum ablation depth was calculated by measuring the difference between preoperative and 3-month postoperative measurements in central corneal thickness using Scheimpflug pachymetry (Pentacam HR; Oculus Optikgeräte, Wetz...
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

Association Between Early Sjögren Markers and Symptoms and Signs of Dry Eye
Conclusions: Most of the individuals with DE tested positive for 1 or more EMS antibodies, including men and Hispanics. Future studies will be needed to understand how to incorporate EMS data into the care of an individual with DE. (Source: Cornea)
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

Psychometric Properties of the Keratoconus Outcomes Research Questionnaire: A Save Sight Keratoconus Registry Study
Purpose: The aim of this study was to evaluate the psychometric properties of the Keratoconus Outcomes Research Questionnaire (KORQ) in patients enrolled in the Save Sight Keratoconus Registry. Methods: A cross-sectional study was conducted utilizing prospectively collected web-based registry data. The psychometric properties of the KORQ were assessed using both classical test theory and Rasch analysis. Andrich group rating scale variant of the Rasch analysis was conducted using Winsteps software, Version 3.92.1. Results: The KORQ was completed by 189 patients with keratoconus (men, 67.7%; white, 69.8%; median age ...
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

Analysis of Compensatory Corneal Epithelial Thickness Changes in Keratoconus Using Corneal Tomography
Conclusions: The “doughnut pattern” of epithelial remodeling in keratoconus is supported by Scheimpflug imaging. This pattern is demonstrated to partially compensate for central corneal steepening seen in keratoconus. (Source: Cornea)
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

Five-Year Graft Survival and Clinical Outcomes of 500 Consecutive Cases After Descemet Membrane Endothelial Keratoplasty
Purpose: To report the 5-year graft survival and clinical outcomes after Descemet membrane endothelial keratoplasty (DMEK). Methods: A retrospective, interventional case series was performed at a tertiary referral center. Five hundred eyes of 393 patients that underwent DMEK for Fuchs endothelial corneal dystrophy, bullous keratopathy, failed previous corneal transplants other than DMEK, or other indications were evaluated for graft survival, best-corrected visual acuity (BCVA), endothelial cell density, postoperative complications, and retransplantation rate. Results: Kaplan–Meier analysis demonstrated an es...
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

Corneal Collagen Cross-Linking With Photoactivated Chromophore for Infectious Keratitis After Penetrating Keratoplasty
Conclusions: PACK-CXL appears to be a promising adjuvant procedure in the management of resistant graft infections by reducing both the duration required for complete healing and rates of graft failure. (Source: Cornea)
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

Quarter-Descemet Membrane Endothelial Keratoplasty: One- to Two-Year Clinical Outcomes
Conclusions: Quarter-DMEK surgery yields visual outcomes similar to those of conventional DMEK and may potentially quadruple the availability of endothelial grafts. Further modifications of the graft preparation and the surgical technique may improve clinical outcomes in terms of lower ECD decrease and fewer graft detachments. (Source: Cornea)
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

Peripheral Hypertrophic Subepithelial Opacities of Corneal Grafts After Deep Anterior Lamellar Keratoplasty
Conclusions: Graft flattening during the early postoperative period and prolonged time interval from surgery to initial suture removal might be factors predisposing to the development of PGHSO. This complication did not affect postoperative visual outcomes when the central 4-mm area of the graft remained clear. (Source: Cornea)
Source: Cornea - February 8, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research

A Direct Visualization of Continuous Meibum Secretion From Orifices of Meibomian Glands to Tear Film: Erratum
No abstract available (Source: Cornea)
Source: Cornea - January 3, 2020 Category: Opthalmology Tags: Errata Source Type: research

Effect of OTX-101, a Novel Nanomicellar Formulation of Cyclosporine A, on Corneal Staining in Patients With Keratoconjunctivitis Sicca: A Pooled Analysis of Phase 2b/3 and Phase 3 Studies: Erratum
No abstract available (Source: Cornea)
Source: Cornea - January 3, 2020 Category: Opthalmology Tags: Errata Source Type: research

Is There Any Role for Lysine in Herpetic Keratitis?
No abstract available (Source: Cornea)
Source: Cornea - January 3, 2020 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Another Comment on: “Microscope-Integrated Optical Coherence Tomography-guided Drainage of Acute Corneal Hydrops in Keratoconus Combined with Suturing and Gas-aided Reattachment of Descemet Membrane”
No abstract available (Source: Cornea)
Source: Cornea - January 3, 2020 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Comment on: “Microscope-Integrated Optical Coherence Tomography-Guided Drainage of Acute Corneal Hydrops in Keratoconus Combined With Suturing and Gas-Aided Reattachment of Descemet Membrane”
No abstract available (Source: Cornea)
Source: Cornea - January 3, 2020 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Reply
No abstract available (Source: Cornea)
Source: Cornea - January 3, 2020 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Comment on: “Safety and Efficacy of Supratarsal Triamcinolone for Treatment of Vernal Keratoconjunctivitis in Ireland”
No abstract available (Source: Cornea)
Source: Cornea - January 3, 2020 Category: Opthalmology Tags: Letters to the Editor Source Type: research

The Prevalence and Risk Factors for Keratoconus: A Systematic Review and Meta-Analysis
Conclusions: The results of this study, as the most comprehensive meta-analysis of keratoconus prevalence and risk factors, showed that keratoconus had a low prevalence in the world and eye rubbing, family history of keratoconus, allergy, asthma, and eczema were the most important risk factors for keratoconus according to the available evidence. (Source: Cornea)
Source: Cornea - January 3, 2020 Category: Opthalmology Tags: Review Source Type: research

Treatment of Acute Corneal Hydrops With Combined Intracameral Gas and Approximation Sutures in Patients With Corneal Ectasia
Conclusions: Combined intracameral gas injection and approximation sutures are probably effective and safe for the treatment of acute CH. This treatment results in rapid recovery with very rare complications. (Source: Cornea)
Source: Cornea - January 3, 2020 Category: Opthalmology Tags: Techniques Source Type: research

Pressure-Induced Interlamellar Stromal Keratitis After Small-Incision Lenticule Extraction Procedure: A Case Report
Conclusions: Clinicians should be aware that PISK is a potential complication of SMILE. Postoperative intraocular pressure measurements are an important aspect of the management of postcorneal refractive surgery patients because the differentiation of PISK from diffuse lamellar keratitis, as well as the early detection and treatment of PISK, can avoid severe complications. (Source: Cornea)
Source: Cornea - January 3, 2020 Category: Opthalmology Tags: Case Report Source Type: research

Topical Vancomycin 5% Is More Efficacious Than 2.5% and 1.25% for Reducing Viable Methicillin-Resistant Staphylococcus aureus in Infectious Keratitis
Conclusions: Vancomycin 5% was most potent for treating experimental MRSA keratitis. The clinician may need to reassess treatment regarding antibacterial efficacy and patient comfort. (Source: Cornea)
Source: Cornea - January 3, 2020 Category: Opthalmology Tags: Basic Investigation Source Type: research

Histone Deacetylase Inhibitors Enhance the Amoebicidal Effect of Low Concentration of Polyhexamethylene Biguanide by Inducing Apoptosis
Conclusions: Combinatorial treatments showed high amoebicidal effects on Acanthamoeba and low CPEs on HCE cells, which suggests their potential application for Acanthamoeba keratitis treatment. (Source: Cornea)
Source: Cornea - January 3, 2020 Category: Opthalmology Tags: Basic Investigation Source Type: research

Revisiting the Safety of the Corneal Collagen Crosslinking Procedure: Evaluation of the Effect of Ultraviolet A Radiation on Retinal Function and Structure
Purpose: To evaluate the effect of ultraviolet A radiation on retinal function and structure after the corneal collagen crosslinking procedure. Methods: In the present prospective, single-center cohort study 17 eyes of 17 patients who underwent collagen crosslinking (Dresden protocol) for the treatment of corneal ectasia were examined preoperatively and at 2 and 6 weeks postoperatively with multifocal electroretinogram and optical coherence tomography. The P1 amplitude density (P1-AD) of the central retinal response was documented in 5 concentric rings, with ring 1 (R1) representing the foveal response and rings 2 to ...
Source: Cornea - January 3, 2020 Category: Opthalmology Tags: Basic Investigation Source Type: research

Changes in the Matrix Metalloproteinase 9 Point-of-Care Test Positivity According to MMP-9 Concentration and Loading Volume
Conclusions: The InflammaDry test had a different detection range depending on MMP-9 formulas; higher concentrations of preform MMP-9 protein were needed to yield positive results. In addition, InflammaDry positivity varied based on the loading volumes. Clinicians should be aware of the possibility of false negatives with low tear volumes despite elevated MMP-9 concentrations. (Source: Cornea)
Source: Cornea - January 3, 2020 Category: Opthalmology Tags: Basic Investigation Source Type: research

In Vitro Evaluation of the Feasibility of Slit-Lamp Nd: YAG Laser Descemetorhexis
Conclusions: Creating a central descemetorhexis with a slit-lamp Nd:YAG laser proved feasible in vitro. This new technical approach might open the door to a customized in vivo “descemetorhexis-only” treatment for Fuchs endothelial corneal dystrophy eyes, while avoiding the risks associated with intraocular surgery. (Source: Cornea)
Source: Cornea - January 3, 2020 Category: Opthalmology Tags: Basic Investigation Source Type: research

Patient-Reported Vision-Related Quality of Life After Boston Type I Keratoprosthesis
Purpose: To determine patient-reported vision-related quality of life (VR-QoL) after Boston type I keratoprosthesis (BKPro) and its determinants. Methods: A cross-sectional study including consecutive consenting BKPro patients was conducted. The French National Eye Institute Visual Function Questionnaire-25 measured postoperative VR-QoL. Medical charts were retrospectively reviewed for demographics, ocular comorbidities, indication for surgery, postoperative visual acuity (VA), and complications. Univariate analyses were used to identify VR-QoL determinants. Multivariate linear regression was additionally performed fo...
Source: Cornea - January 3, 2020 Category: Opthalmology Tags: Clinical Science Source Type: research