Clinical and Histological Characterization of Toxic Keratopathy From Depatuxizumab Mafodotin (ABT-414), an Antibody-Drug Conjugate: Retraction
No abstract available (Source: Cornea)
Source: Cornea - October 6, 2018 Category: Opthalmology Tags: Retraction Source Type: research

Severe Ocular Burn Secondary to Isopropyl Alcohol Exposure
No abstract available (Source: Cornea)
Source: Cornea - October 6, 2018 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Reply
No abstract available (Source: Cornea)
Source: Cornea - October 6, 2018 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Comment on: Sulfur Hexafluoride 20% Versus Air 100% for Anterior Chamber Tamponade in Descemet Membrane Endothelial Keratoplasty A Meta-Analysis
No abstract available (Source: Cornea)
Source: Cornea - October 6, 2018 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Reply
No abstract available (Source: Cornea)
Source: Cornea - October 6, 2018 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Just What Do We Know About Corneal Collagen Turnover?
No abstract available (Source: Cornea)
Source: Cornea - October 6, 2018 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Viability of Descemet Membrane Endothelial Keratoplasty Grafts Folded in the Eye Bank
Conclusions: Despite additional manipulation of the graft, trifolding of Descemet membrane and endothelium may be performed by an eye bank technician without significantly increased cell loss relative to graft preparation as a scroll. (Source: Cornea)
Source: Cornea - October 6, 2018 Category: Opthalmology Tags: Techniques Source Type: research

Late-Onset Microsporidial Keratitis in Femtosecond Astigmatic Keratotomy After Laser-Assisted Phacoemulsification
Conclusions: This is the first reported case of microsporidial keratitis presenting as a late-onset infection after femtosecond laser–assisted AK. (Source: Cornea)
Source: Cornea - October 6, 2018 Category: Opthalmology Tags: Case Report Source Type: research

Squamous Cell Carcinoma Invading a Transplanted Cornea: Eye- and Vision-Sparing Palladium-103 Plaque Radiation Therapy for a Functionally Monocular Patient
Conclusions: Transcorneal intraocular tumor invasion was controlled using palladium-103 ophthalmic plaque radiation therapy applied through the natural and donor cornea. Definitive treatment resulted in local tumor control and preservation of vision. (Source: Cornea)
Source: Cornea - October 6, 2018 Category: Opthalmology Tags: Case Report Source Type: research

Impact of Iontophoresis and PACK-CXL Corneal Concentrations of Antifungals in an In Vivo Model
Conclusions: Iontophoresis seems to provide the highest VRZ concentration and highest antifungal activity in the cornea compared with other treatment applications for C. albicans and F. solani keratitis. (Source: Cornea)
Source: Cornea - October 6, 2018 Category: Opthalmology Tags: Basic Investigation Source Type: research

Comparative Study of Ocular Pharmacokinetics of Gatifloxacin Between Continuous Lavage and Hourly Topical Instillation in Rabbits
Conclusions: Compared with hourly topical instillation, continuous lavage through the Morgan lens could achieve significantly higher concentrations in ocular tissues within a short period, especially in the cornea. Continuous lavage may be a much more efficient way to treat recalcitrant corneal infections. (Source: Cornea)
Source: Cornea - October 6, 2018 Category: Opthalmology Tags: Basic Investigation Source Type: research

Survival Analysis of Corneal Densitometry After Collagen Cross-Linking for Progressive Keratoconus
Conclusions: Corneal cross-linking halted keratoconus progression when detectable haze was present. There was continuous corneal flattening measured at 1 year after haze resolution. Thinning of the cornea was seen only when haze was detectable after cross-linking. (Source: Cornea)
Source: Cornea - October 6, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Keratoconus Progression After Corneal Cross-Linking in Eyes With Preoperative Maximum Keratometry Values of 58 Diopters and Steeper
Conclusions: The incidence of progression (23% at 1 and 18% at 2 years, respectively) is considerably higher than in previously reported results of CXL in eyes with mean Kmax ≥58.0 D. To the best of our knowledge, this study represents the largest number of such steep corneas analyzed with respect to long-term progression after CXL. (Source: Cornea)
Source: Cornea - October 6, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Anterior Segment Changes After Femtosecond Laser-Assisted Implantation of a 355-Degree Intrastromal Corneal Ring Segment in Advanced Keratoconus
Purpose: To study anterior segment changes after implantation of a Keraring with a 355-degree arc length in central advanced keratoconus. Methods: Thirty eyes of 22 patients with advanced central keratoconus (grade 3) and absent corneal scarring underwent femtosecond laser-assisted (VisuMax) implantation of a Keraring 355-degree arc length intrastromal corneal ring segment (ICRS) with a segment thickness of 300 μm. Comprehensive ocular evaluations were performed preoperatively and postoperatively to assess uncorrected distance visual acuity, corrected distance visual acuity, K1, K2, Kmax, corneal volume, anterior c...
Source: Cornea - October 6, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Changes in the ABCD Keratoconus Grade After Intracorneal Ring Segment Implantation
Purpose: To assess the changes in the ABCD keratoconus staging system 6 months after intracorneal ring segment implantation. Methods: Fifty eyes of 50 patients with keratoconus who were implanted with the Keraring (Mediphacos, Belo Horizonte, Brazil) using the femtosecond laser were assessed. Preoperative and postoperative assessments included determination of distance uncorrected visual acuity and distance corrected visual acuity (DCVA), refraction, and Scheimpflug tomography with the Pentacam HR. In the ABCD keratoconus staging system, the elements A, B, C, and D stand for anterior and posterior radii of curvature i...
Source: Cornea - October 6, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Prevalence of Novel Candidate Sjogren Syndrome Autoantibodies in the Dry Eye Assessment and Management (DREAM) Study
Purpose: To evaluate the prevalence of novel candidate Sjogren syndrome (SS) autoantibodies [salivary protein-1 (SP-1), parotid secretory protein, carbonic anhydrase 6] in the DRy Eye Assessment and Management (DREAM) cohort, a study evaluating the effectiveness of omega-3 fatty acid supplements for the treatment of dry eye. Methods: Participants underwent ocular surface examinations and serological testing for traditional and novel SS autoantibodies. Dry eye assessment and management participants were categorized into the following 3 groups: 1) no history of SS or other autoimmune diseases and negative traditional SS...
Source: Cornea - October 6, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Endothelial Cell Loss in Obstetric Forceps-Related Corneal Injury: A Longitudinal Specular Microscopic Study
Conclusions: In children with forceps-related corneal injury, lower ECD with a higher annual decrease can be assessed with specular microscopy for risk stratification and parental counseling purposes. (Source: Cornea)
Source: Cornea - October 6, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Effect of Cataract Surgery on the Refractive Index of the Cornea Estimated by Optical Pachymetry
Conclusions: The RI of the human cornea along the antero–posterior axis can be estimated using a modified application of traditional optical pachymetry. The average values for the corneal RI were higher compared with those reported in previous reports. The change in the RI after phacoemulsification could be predicted from the preoperative value. (Source: Cornea)
Source: Cornea - October 6, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Comparative Outcomes of Boston Keratoprosthesis Type 1 Implantation Based on Vision in the Contralateral Eye
Conclusions: Most patients with failed keratoplasty who were implanted with a Boston keratoprosthesis type I experienced improved vision, and visual acuity of the contralateral eye did not seem to influence the visual outcome of surgery. However, patients with good vision in the contralateral eye were more likely to experience complications, possibly because of reduced vigilance when the other eye has ambulatory vision. (Source: Cornea)
Source: Cornea - October 6, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Outcomes of the Boston Type I Keratoprosthesis as the Primary Penetrating Corneal Procedure
Conclusions: In the setting of preexisting ocular comorbidities in which PK is associated with poor outcomes and KPros have been associated with an increased incidence of postoperative complications, primary KPro is associated with significantly greater % of eyes with CDVA ≥ 20/200 in the first 4 years. However, given a significantly higher incidence of postoperative intraocular pressure elevation in these eyes, longer follow-up is needed to determine whether the difference in CDVA is maintained. (Source: Cornea)
Source: Cornea - October 6, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Infectious Keratitis After Ocular Surface Stem Cell Transplantation
Purpose: To describe the rate, clinical/microbiological characteristics, and outcomes of infectious keratitis in eyes with limbal stem cell deficiency after ocular surface stem cell transplantation (OSST). Methods: In this retrospective chart review of 278 eyes that underwent OSST between January 2006 and December 2016, eyes treated for previous infectious keratitis (bacterial, fungal, or viral) were included. Demographics, risk factors, course, microbiological characteristics, and outcomes were assessed. Results: A total of 52 eyes (18.7%) of 48 patients (28 men and 20 women) developed 75 episodes (culture-proven ...
Source: Cornea - October 6, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Spectral Domain Anterior Segment Optical Coherence Tomography in Fungal Keratitis
Purpose: To evaluate the use of spectral domain anterior segment optical coherence tomography (SD-ASOCT) in fungal keratitis. Methods: Fifty eyes of 50 patients with fungal keratitis were recruited. Serial ASOCT was performed on days 0, 7, 14, 21, 28, 42, and 56. Corneal thickness (CT) in the infiltrate area, infiltrate thickness (IT), and infiltrate width were measured at each follow-up. The presence of any specific feature on ASOCT was evaluated. Results: Mean CT and IT at presentation were 650.5 ± 108 μm and 401.1 ± 91 μm, which reduced significantly at each follow-up [on days 7, 14, 28, and ...
Source: Cornea - October 6, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Acanthamoeba Keratitis: Are Recent Cases More Severe?
Conclusions: In recent years, the general profile of patients with AK has changed at WEH. Currently, we are treating older patients with more severe keratitis who are presenting later and with worse vision compared with our previous patients. At the same time, treatment outcomes have been poorer. (Source: Cornea)
Source: Cornea - October 6, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

PACK-CXL in Reducing the Time to Heal in Suppurative Corneal Ulcers: Observations of a Pilot Study From South India
Conclusions: CXL reduced the time to heal in suppurative corneal ulcers less than 6 mm in diameter and can be used as an adjuvant to antimicrobial therapy. (Source: Cornea)
Source: Cornea - October 6, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Goldmann Applanation Tonometer Versus Ocular Response Analyzer for Measuring Intraocular Pressure After Descemet Stripping Automated Endothelial Keratoplasty
Purpose: To evaluate agreement between IOP measured using the ocular response analyzer (ORA) versus using the Goldmann applanation tonometer (GAT) in patients treated by Descemet stripping automated endothelial keratoplasty (DSAEK). Methods: This prospective, case–control study comprised 38 normal eyes and 37 post-DSAEK eyes. IOP was measured using the GAT (IOPGAT). The ORA was used to measure corneal biomechanics and cornea-compensated IOP (IOPCC). Corneal hysteresis (CH), corneal resistance factor, and IOP measurements of the 2 groups were compared. Intertonometer agreement was evaluated in each study group us...
Source: Cornea - October 6, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Fungal Interface Keratitis After Descemet Membrane Endothelial Keratoplasty
Conclusions: Fungal IK is a rare complication after DMEK. Based on our experience, we believe that treatment of early fungal IK with aggressive presentation should include both immediate graft exchange and intracameral application of voriconazole and amphotericin, in addition to topical and systemic antifungal treatment. Graft exchange seems not to be mandatory in late infections. (Source: Cornea)
Source: Cornea - October 6, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Evaluation of Anterior and Posterior Corneal Irregularity After Descemet Membrane Endothelial Keratoplasty
Purpose: To investigate the changes in anterior and posterior corneal irregularity after Descemet membrane endothelial keratoplasty (DMEK). Methods: This retrospective study included 27 eyes of 23 patients who underwent DMEK and 27 eyes of age-matched healthy controls. Corneal irregularity indexes, surface regularity of height (SR_H), and higher-order aberrations were evaluated in 4- and 6-mm diameters of the cornea, preoperatively and postoperatively, using anterior segment optical coherence tomography. Results: The best spectacle-corrected visual acuity (logarithm of the minimum angle of resolution) improved from...
Source: Cornea - October 6, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Short Axial Length and Iris Damage Are Associated With Iris Posterior Synechiae After Descemet Membrane Endothelial Keratoplasty in Asian Eyes
Purpose: To evaluate the frequency and severity of iris posterior synechiae after Descemet membrane endothelial keratoplasty (DMEK) and to investigate possible causes of iris posterior synechiae. Methods: Twenty-three eyes were investigated in 20 Asian patients who underwent DMEK 1 month after phacoemulsification and intraocular lens implantation surgery. A preexisting iris damage score was defined by iris damage and classified into 5 grades. Six months after DMEK, the iris posterior synechiae severity score was evaluated based on the extent of posterior synechiae, according to every 45 degrees of the pupillary rim (p...
Source: Cornea - October 6, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Clinical Outcomes of Descemet Membrane Endothelial Keratoplasty in Eyes With Previous Radial Keratotomy
Conclusions: DMEK is technically feasible in eyes with previous RK and may provide excellent outcomes. A significant change in the anterior corneal contour and associated refractive power of the eye may be anticipated depending on the amount of preoperative corneal edema and the number of RK incisions. (Source: Cornea)
Source: Cornea - October 6, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Influence of Postoperative Intraocular Pressure on Graft Detachment After Descemet Membrane Endothelial Keratoplasty
In this study, postoperative intraocular pressure (IOP) is investigated in this regard. Methods: In total, 1047 DMEK procedures in patients with Fuchs endothelial dystrophy or bullous keratopathy were reviewed. All rebubbling procedures were recorded as well as postoperative IOP values (first measure 2 hours postoperatively and highest and lowest value within 3 days after surgery), donor factors (donor age, organ culture time, and endothelial cell count), and whether DMEK surgery had been combined with cataract surgery (triple-DMEK). Incidence rates were estimated with the Kaplan–Meier method. Cox regression was u...
Source: Cornea - October 6, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Corneal Cross-Linking: Current USA Status Report From the Cornea Society
Abstract: The initial published clinical report on riboflavin/ultraviolet A corneal cross-linking (CXL) for treatment of progressive keratoconus dates back to 2003. CXL has since then been widely used outside the United States for treatment of progressive keratoconus and post-laser in situ keratomileusis ectasia. The Food and Drug Administration (FDA) approved Avedro Inc.'s corneal cross-linking system (KXL) for treatment of patients with progressive keratoconus and post-laser in situ keratomileusis ectasia in April 2016. The procedure is not currently approved for stable keratoconus. There are 2 FDA-approved topical oph...
Source: Cornea - September 12, 2018 Category: Opthalmology Tags: Special Article Source Type: research

Human Corneal Changes After Rose Bengal Photodynamic Antimicrobial Therapy for Treatment of Fungal Keratitis
No abstract available (Source: Cornea)
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Letter to the Editor Source Type: research

Topical Tacrolimus as Adjuvant Therapy to Corticosteroids in Acute Endothelial Graft Rejection After Penetrating Keratoplasty: A Randomized Controlled Trial Erratum
No abstract available (Source: Cornea)
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Erratum Source Type: research

Comparative Image Atlas of Current and New Technologies in Corneal Donor Tissue Evaluation: Erratum
No abstract available (Source: Cornea)
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Erratum Source Type: research

Femtosecond Laser–Assisted Graft Preparation for Descemet Membrane Endothelial Keratoplasty
Conclusions: The femtosecond laser may be a useful adjunct in graft preparation for DMEK. (Source: Cornea)
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Techniques Source Type: research

Descemet Stripping Automated Endothelial Keratoplasty With a Retention Suture: Description of a Technique for Patients at High Risk of Graft Detachment
Conclusions: A cloverleaf or parallel retention suture in conjunction with Descemet stripping automated endothelial keratoplasty seems to reduce the risk of detachment in high-risk patients, while maintaining adequate cell density and graft clarity at 1 year. (Source: Cornea)
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Techniques Source Type: research

Novel Technique for Improving Graft Unfolding in Vitrectomized Eyes Using a Temporary Diaphragm in Descemet Membrane Endothelial Keratoplasty
Purpose: To describe a new surgical technique for performing Descemet membrane endothelial keratoplasty (DMEK) using a temporary hydrophilic methacrylate sheet in the anterior chamber in cases of previous vitrectomy with complete removal of the vitreous body. Methods: Medical records were reviewed for baseline and follow-up best spectacle-corrected visual acuity, endothelial cell count, and indication for DMEK using a temporary hydrophilic methacrylate sheet. Operative notes were analyzed in all cases to identify any specific intraoperative event. Results: Seven eyes of 7 patients were included in this analysis. Me...
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Techniques Source Type: research

Primary Modified Predescemetic Deep Anterior Lamellar Keratoplasty in Acute Corneal Hydrops
Conclusions: Primary pdDALK was possible as single-stage definitive treatment with early visual rehabilitation and avoidance of scarring in our case series. Simultaneous correction of pathology by closure of DM break, anatomical correction of ectasia and thinning, optical correction by improved corneal topography and by regaining corneal structure and transparency, and retention of host DM and endothelium are advantages. Advanced DALK surgeons may use this technique. (Source: Cornea)
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Case Report Source Type: research

Conjunctival Eosinophilic Masses With Chronic Eosinophilic Pneumonia
Conclusions: Based on the clinical course and histopathology, the conjunctival proliferative masses in our case were assumed to be associated with CEP. (Source: Cornea)
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Case Report Source Type: research

“Eye Dropping”—A Case Report of Transconjunctival Lysergic Acid Diethylamide Drug Abuse
Conclusions: To the best of our knowledge, this is the first reported case of bilateral hemorrhagic conjunctival abrasion and corneal abrasion secondary to LSD. “Kissing” conjunctival lesions, which have been previously reported with heroin use, should raise suspicion for drug abuse. (Source: Cornea)
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Case Report Source Type: research

Characterization of Corneal Donor Tissue Lesions by Anterior Segment Optical Coherence Tomography Compared With Eye Bank Technician Slit-Lamp Examination
Conclusions: Our study highlights both advantages and limitations of OCT compared with technician SLE in the evaluation of donor corneal tissue. Although OCT may miss some peripheral lesions and LASIK scars that are identifiable on SLE, OCT's depth resolution is helpful in differentiating whether shallow anterior opacities actually extend deeper into the stroma or are confined superficially to the epithelium. (Source: Cornea)
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Basic Investigation Source Type: research

Therapeutic Effects of Topical 8-Oxo-2’-deoxyguanosine on Ethanol-Induced Ocular Chemical Injury Models
Purpose: To evaluate the therapeutic effects of topical 8-oxo-2’-deoxyguanosine (8-oxo-dG) on experimental ocular chemical injury models. Methods: We created ocular chemical injury models with 8-week-old BALB/c mice (n = 70) by applying 100% ethanol; the mice were then treated with 8-oxo-dG eye drops 10 and 5 mg/mL and phosphate-buffered saline (PBS) twice daily. After 7 days, clinical findings such as corneal integrity, clarity, and neovascularization were assessed. Histology, immunohistochemistry findings, and inflammatory cytokine levels using real-time polymerase chain reactions in the corneas of the mice we...
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Basic Investigation Source Type: research

Association Between Advanced Keratoconus and Serum Levels of Zinc, Calcium, Magnesium, Iron, Copper, and Selenium
In this study, 50 patients with advanced KCN and 50 control subjects were included. Plasma levels of Zn, Ca, Mg, Fe, Cu, and Se were compared between the groups. Results: Mean ± SD age of the patients in the case and control groups was 29.3 ± 3.5 and 28.9 ± 5.9 years, respectively (P = 0.669). Among serum parameters, there were no statistically significant differences between the 2 groups in serum levels of Ca, Mg, and Fe (P> 0.05), whereas serum levels of Zn and Cu were significantly lower in the case group than the control group [65.92 ± 7.90 vs. 87.36 ± 13.64 μg/dL and 78.48 &...
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Basic Investigation Source Type: research

Clinical Outcomes After Implantation of 320°-Arc Length Intrastromal Corneal Ring Segments in Keratoconus
Purpose: To evaluate the clinical outcomes after implantation of a new 320°-arc length Ferrara intrastromal corneal ring segment (320-ICRS) in eyes of patients with keratoconus. Methods: A multicentric nonrandomized study was conducted in which a new 320-ICRS was placed in 138 eyes of 130 patients with keratoconus. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), keratometry, corneal volume, asphericity, lines of vision gain/loss, and vectorial analysis were assessed preoperatively and at the final follow-up visit after the procedure. Results: The mean follow-up time was 6.2 &...
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

High-Resolution Anterior Segment Optical Coherence Tomography in Intraepithelial Versus Invasive Ocular Surface Squamous Neoplasia
Conclusions: A visible clear plane of separation and increased thickness on ASOCT may serve as surrogate markers of intraepithelial OSSN and help differentiate it from invasive OSSN. (Source: Cornea)
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Conjunctival Squamous Neoplasia: Staging and Initial Treatment
Conclusions: The AJCC stage does not correlate with the initial treatment of CIN. The AJCC T3 category should be reviewed to differentiate diffuse SCCs with broad surface extension from tumors with deep scleral invasion. (Source: Cornea)
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Infrared Video Meibography of Lower Lid Meibomian Glands Shows Easily Distorted Glands: Implications for Longitudinal Assessment of Atrophy or Growth Using Lower Lid Meibography
Purpose: To evaluate measurement reliability of the meibomian gland (MG) tissue area during infrared video meibography (IR-VM) of the lower lid. Methods: This is a retrospective analysis, using ImageJ, of IR-VM of 17 lids of 11 consecutive patients (age 56.6 ± 15.9 years; 9 females and 2 males) focusing on the presence of a statistically significant variation of the MG tissue area and the MG tissue area relative to the total measurement field (TMF) secondary to inadvertent lid distortion and/or an altered vertical gaze direction during a single-image acquisition video sequence. Results: For lids with distort...
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Effect of the Meibomian Gland Squeezer for Treatment of Meibomian Gland Dysfunction
Purpose: To investigate the effect of the meibomian gland squeezer for treatment of meibomian gland dysfunction (MGD). Methods: Seventy patients (140 eyes) with MGD were randomly divided into 2 groups: 36 patients who were treated by the meibomian gland squeezer as the treatment group and 34 patients were selected as the control group. Patients were evaluated at baseline, and 2-week and 1-month visits for subjective symptoms, objective signs and pain assessments, including ocular symptom scores, Ocular Surface Disease Index, tear breakup time, corneal fluorescein staining, Schirmer scores with no anesthetic (Schirmer ...
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Meibomian Gland Dropout in Hematological Patients Before Hematopoietic Stem Cell Transplantation
Purpose: To perform qualitative and quantitative analysis of meibomian gland (MG) dropout in hematological patients before hematopoietic stem cell transplantation (HSCT) and to correlate it with both ocular surface and hematological characteristics. Methods: This prospective study included 46 consecutive patients undergoing HSCT and 30 age- and sex-matched healthy controls. Noninvasive meibography of the lower eyelid, meiboscore (Pult scale), Schirmer test type I, tear film breakup time, and corneal and conjunctival staining were measured. Subjective symptoms were scored by the Ocular Surface Disease Index. The dry ey...
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Development of the Modified Lenticule Edge Dissection Technique for Small Incision Lenticule Extraction
Conclusions: The modified lenticule edge dissection technique of SMILE is simpler and faster in identifying the correct dissection plane. It is efficient in reducing surgical manipulation, shortening the learning curve required for lenticule dissection, and allows surgeons to perform SMILE more safely and efficiently. (Source: Cornea)
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research