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No abstract available (Source: Cornea)
Source: Cornea - May 8, 2018 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Mechanism of Immunologic Rejection After Deep Anterior Lamellar Keratoplasty
No abstract available (Source: Cornea)
Source: Cornea - May 8, 2018 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Corneal Cross-Linking for Pediatric Keratcoconus Review
Conclusions: Studies of cross-linking in pediatric patients are sparse, with relatively short follow-up times, and mostly on small groups of patients. Treatment with cross-linking halts progression of keratoconus in the pediatric population, and early treatment seems to be cost-effective compared with later penetrating keratoplasty. Long-term effects and regression rates remain unclear, and further studies are needed in this population. (Source: Cornea)
Source: Cornea - May 8, 2018 Category: Opthalmology Tags: Review Source Type: research

“Meniscus Sign” to Identify the Lenticule Edge in Small-Incision Lenticule Extraction
Conclusions: The meniscus sign helps to identify the lenticule edge and correct dissection planes and provides a visual landmark during the entire surgical procedure. (Source: Cornea)
Source: Cornea - May 8, 2018 Category: Opthalmology Tags: Techniques Source Type: research

Topical Interferon Alpha-2b Induced Reactive Lymphoid Hyperplasia Masquerading as Orbital Extension of Ocular Surface Squamous Neoplasia
Conclusions: Excisional biopsy of the lesions confirmed benign reactive lymphoid hyperplasia and resolved with no recurrence. (Source: Cornea)
Source: Cornea - May 8, 2018 Category: Opthalmology Tags: Case Report Source Type: research

Descemet Membrane Endothelial Keratoplasty (DMEK) Under Previous DMEK for Secondary Endothelial Graft Failure
Conclusions: A second DMEK graft without peeling or removing the first DMEK graft is an alternative treatment option for DMEK graft secondary failure. This approach is able to achieve full anatomical and functional restoration of the prefailure status. This technique allows a second graft surgery to be easier, faster, and with less intraoperative risks (as a result of a potential difficult host descemetorhexis). Future studies with larger samples and a longer follow-up are necessary to confirm the short and long-term outcomes of this new DMEK under DMEK approach. (Source: Cornea)
Source: Cornea - May 8, 2018 Category: Opthalmology Tags: Case Report Source Type: research

Confocal Microscopy Observation of Cornea Verticillata After Vandetanib Therapy for Medullary Thyroid Carcinoma
Conclusions: In both patients, vandetanib seemed to be the cause of CV. The CM images supported the idea of drug–lipid complex deposits in vandetanib-induced CV. (Source: Cornea)
Source: Cornea - May 8, 2018 Category: Opthalmology Tags: Case Report Source Type: research

Characteristics of Linear Interstitial Keratitis by In Vivo Confocal Microscopy and Anterior Segment Optical Coherence Tomography
Conclusions: Although linear IK appeared as localized anterior stromal inflammation on AS-OCT, panstromal inflammation was revealed by IVCM. (Source: Cornea)
Source: Cornea - May 8, 2018 Category: Opthalmology Tags: Case Report Source Type: research

Feasibility Study of Human Corneal Endothelial Cell Transplantation Using an In Vitro Human Corneal Model
Conclusions: Direct transplantation of cultured human CE cells and immortalized HCEC-12 to bare posterior corneal stroma resulted in formation of an endothelial monolayer and restoration of stromal hydration to physiological thickness, demonstrating the feasibility of cell therapy in treatment of CE decompensation in a human in vitro model. (Source: Cornea)
Source: Cornea - May 8, 2018 Category: Opthalmology Tags: Basic Investigation Source Type: research

Keratoprosthesis Decentration and Tilt Results in Degradation in Image Quality
Conclusions: Decentration of up to 0.5 mm had no significant impact on image quality and an attempt at good intraoperative centration of the KPro within this range is important. Conversely, decentration of 0.9 mm or more during surgical implantation can result in significant degradation in retinal image quality including astigmatism. The effect is greater in the pseudophakic eye. (Source: Cornea)
Source: Cornea - May 8, 2018 Category: Opthalmology Tags: Basic Investigation Source Type: research

Descemet Membrane Endothelial Keratoplasty Learning Curve for Graft Preparation in an Eye Bank Using 645 Donor Corneas
Conclusions: There is a learning curve for DMEK graft preparation. ECL and tissue wastage can be reduced with practice and skills. However, each operator may be limited to his or her own learning capability. (Source: Cornea)
Source: Cornea - May 8, 2018 Category: Opthalmology Tags: Basic Investigation Source Type: research

Cellular Proliferation and Migration of Human Pterygium Cells: Mitomycin Versus Small-Molecule Inhibitors
Conclusions: In our study, MMC induced cell death in pterygium and conjunctival cell lines, whereas Nutlin had a targeted impact on pterygium cells. Our results implied that MMC inhibited both pterygium cell proliferation and migration through an apoptosis-independent pathway. (Source: Cornea)
Source: Cornea - May 8, 2018 Category: Opthalmology Tags: Basic Investigation Source Type: research

Epithelial Keratitis After Cataract Surgery
Purpose: To evaluate the incidence, related perioperative factors, clinical characteristics, and possible etiologies of epithelial keratitis after cataract surgery. Methods: A retrospective chart review of 666 eyes in 666 patients who underwent cataract surgery was performed to evaluate the incidence of epithelial keratitis and related factors in the postoperative period. Results: Postoperative epithelial keratitis developed in 15 eyes. Eleven of the 15 eyes were diagnosed with herpes simplex keratitis (HSK); 10 of the 11 eyes were diagnosed by polymerase chain reaction, and the remaining 1 eye by clinical diagnosi...
Source: Cornea - May 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Role of Dendritic Cells and Inflammatory Cells in Herpetic Endotheliitis: Analysis Using In Vivo Confocal Microscopy
Purpose: To observe the pathological changes in dendritic cells (DCs) and inflammatory cells in the corneal epithelium and endothelium using in vivo confocal microscopy during the management of herpetic endotheliitis. Methods: A total of 110 eyes with herpetic endotheliitis were included. All patients were treated with antiviral agents combined with glucocorticoids. Changes in corneal edema were observed using slit-lamp microscopy and anterior segment optical coherence tomography. DCs and inflammatory cells in the epithelium and endothelium were detected using in vivo confocal microscopy before treatment and at 1 to 2...
Source: Cornea - May 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Systemic Absorption of Mitomycin-C When Used in Pterygium Surgery
Conclusions: In this study of 27 patients treated with topical application of MMC for pterygium surgery, there was no measurable evidence of systemic drug absorption. Although systemic absorption has been found with the use of larger quantities of MMC, there is an extremely low likelihood of systemic absorption or toxicity of MMC after pterygium surgery. (Source: Cornea)
Source: Cornea - May 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Ocular Surface Workup With Automated Noninvasive Measurements for the Diagnosis of Meibomian Gland Dysfunction
Purpose: To analyze diagnostic performance of an ocular surface workup based on automated noninvasive measurements in the diagnosis of meibomian gland dysfunction (MGD). Methods: Two hundred ninety-eight eyes of 149 patients with MGD and 54 eyes of 27 control patients were analyzed. Ocular Surface Disease Index (OSDI), noninvasive breakup time (BUT), lipid layer thickness, meibomian gland loss, and tear osmolarity were calculated. The correlations among variables in the MGD group were analyzed. The area under the curve (AUC) of receiver operating characteristic curves was calculated. Results: OSDI, noninvasive BUT,...
Source: Cornea - May 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Perioperative Ocular Parameters Associated With Persistent Dry Eye Symptoms After Cataract Surgery
Purpose: To evaluate perioperative dry eye (DE) syndrome and meibomian gland dysfunction (MGD) parameters associated with persistent DE symptoms after cataract surgery. Methods: We enrolled patients who underwent uncomplicated cataract surgery without previous ocular comorbidities and previous use of ophthalmic treatment except for artificial tears at a single tertiary hospital. Lipid layer thickness, meibomian gland (MG) dropout, tear breakup time, Oxford staining score, lid margin abnormality, meibum quality, meibum expressibility, MG orifice obstruction, MGD stage, Ocular Surface Disease Index (OSDI), and Schirmer ...
Source: Cornea - May 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Accuracy of Corneal Thickness by Swept-Source Optical Coherence Tomography and Scheimpflug Camera in Virgin and Treated Fuchs Endothelial Dystrophy
Purpose: To assess intraobserver repeatability, intersession reproducibility, and agreement of swept-source Fourier-domain optical coherence tomography (SS-OCT) and the Scheimpflug camera in measuring corneal thickness in virgin and grafted eyes with Fuchs endothelial corneal dystrophy (FECD). Methods: Thirty-six control eyes, 35 FECD eyes, 30 FECD with corneal edema eyes, 25 Descemet stripping automated endothelial keratoplasty (DSAEK) eyes, and 29 Descemet membrane endothelial keratoplasty (DMEK) eyes were included. The apical center, pupillary center, and thinnest corneal thickness were determined in 3 consecutive ...
Source: Cornea - May 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

A New Approach for the Calculation of Total Corneal Astigmatism Considering the Magnitude and Orientation of Posterior Corneal Astigmatism and Thickness
Purpose: To evaluate a new method of calculation of total corneal astigmatism based on Gaussian optics and the power design of a spherocylindrical lens (C) in the healthy eye and to compare it with keratometric (K) and power vector (PV) methods. Methods: A total of 92 healthy eyes of 92 patients (age, 17–65 years) were enrolled. Corneal astigmatism was calculated in all cases using K, PV, and our new approach C that considers the contribution of corneal thickness. An evaluation of the interchangeability of our new approach with the other 2 methods was performed using Bland–Altman analysis. Results: Stat...
Source: Cornea - May 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

A Comparative Study of Central Corneal Epithelial, Stromal, and Total Thickness in Males With and Without Primary Open-Angle Glaucoma
Purpose: To compare the central corneal epithelial thickness (CET), stromal thickness (CST), and total thickness (CCT) in males with and without primary open-angle glaucoma and to determine the factors associated with corneal thickness. Methods: A case–control study was conducted to evaluate 116 male patients at the Miami Veterans Affair Medical Center. Subjects with available anterior segment optical coherence tomography images (Cirrus HD-OCT, Carl Zeiss Meditec Inc, Dublin, CA) were retrospectively classified into 2 groups by glaucoma status. CET, CST, and CCT measurements between the groups were compared. Ass...
Source: Cornea - May 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Outcomes of Trabeculectomy and Glaucoma Drainage Devices for Elevated Intraocular Pressure After Penetrating Keratoplasty
Purpose: To assess and compare the outcomes of trabeculectomy with and without antimetabolites (AMs) and glaucoma drainage devices (GDDs) in the management of elevated intraocular pressure (IOP) after penetrating keratoplasty (PK). Methods: Data of 84 eyes of 81 patients who underwent trabeculectomy (12 eyes without an AM and 42 eyes with an AM) or GDD implantation (30 eyes) after PK were reviewed retrospectively. The main outcome measures were IOP control, corneal graft survival, and postoperative ocular complications. Results: At the final visit, IOP success ( (Source: Cornea)
Source: Cornea - May 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Cumulative Endothelial Cell Loss in Descemet Membrane Endothelial Keratoplasty Grafts From Preparation Through Insertion With Glass Injectors
Purpose: Evaluation of cumulative Descemet membrane endothelial keratoplasty endothelial cell loss (ECL) from preparation through injection using 2 different glass injectors. Methods: Eighteen Descemet membrane endothelial keratoplasty grafts with “S” stamps were prepared by eye bank technicians. Nine grafts were assigned to injection with a modified glass Jones tube injector with a 2.4-mm opening and 9 were assigned to injection with the DORC glass pipette injector ( (Source: Cornea)
Source: Cornea - May 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Sulfur Hexafluoride 20% Versus Air 100% for Anterior Chamber Tamponade in DMEK: A Meta-Analysis
Conclusions: In DMEK, 20% SF6 tamponade and longer postoperative time supine were associated with 58% fewer rebubbling procedures, and an ECL not statistically different from using 100% air. (Source: Cornea)
Source: Cornea - May 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Nomogram to Predict Graft Thickness in Descemet Stripping Automated Endothelial Keratoplasty: An Eye Bank Study
Conclusions: We report a nomogram to predict thickness of DSAEK corneal grafts prepared in an eye bank setting, which was accurate to within 25 μm 80% of the time. Other eye banks could consider performing similar analyses. (Source: Cornea)
Source: Cornea - May 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Descemet Membrane Endothelial Keratoplasty for Failed Deep Anterior Lamellar Keratoplasty: A Case Series
Conclusions: DMEK surgery may be effective in managing DALK failure. (Source: Cornea)
Source: Cornea - May 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Outcomes of Descemet Membrane Endothelial Keratoplasty in Eyes With a Previous Descemet Stripping Automated Endothelial Keratoplasty Graft
Conclusions: DMEK is effective for replacing previous DSAEK not only for graft failure but also for suboptimal visual outcomes. (Source: Cornea)
Source: Cornea - May 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

In Vivo Endothelial Cell Density Decline in the Early Postoperative Phase After Descemet Membrane Endothelial Keratoplasty
Conclusions: After DMEK, ECD shows an in vivo decline of 18% from 1 day to 6 months postoperatively, with a sharp 13% drop in the first week, and a slower decrease thereafter. The remaining difference of 20% from preoperative ECD values may be attributed to a measurement error in the eye bank with an overestimation of the graft's viable endothelial cell population and/or intraoperative trauma to the graft. (Source: Cornea)
Source: Cornea - May 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Letter to the Editor in Response to Kim et al, “Effect of Histocompatibility Y Antigen Matching on Graft Survival in Primary Penetrating Keratoplasty.”
No abstract available (Source: Cornea)
Source: Cornea - March 31, 2018 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Lamina Cribrosa Thickness in Patients With Keratoconus
No abstract available (Source: Cornea)
Source: Cornea - March 31, 2018 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Reply
No abstract available (Source: Cornea)
Source: Cornea - March 31, 2018 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Standardizing the Descemet Membrane Endothelial Keratoplasty Graft Preparation Method in the Eye Bank—Experience of 527 Descemet Membrane Endothelial Keratoplasty Tissues: A Proposed Modification
No abstract available (Source: Cornea)
Source: Cornea - March 31, 2018 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Five Keratoplasties From One Donor Cornea
Conclusions: In this limited series, we demonstrate that 1 donor cornea can be successfully used for 5 recipients. Although performing DALK and Q-DMEK on a single day is technically challenging, it is feasible and can dramatically reduce the shortage and the cost of corneal tissue. Strict case selection is necessary. Further study on this approach is required. (Source: Cornea)
Source: Cornea - March 31, 2018 Category: Opthalmology Tags: Techniques Source Type: research

Technique for Preparing Ultrathin and Nanothin Descemet Stripping Automated Endothelial Keratoplasty Tissue
Conclusions: We propose the term “NT-DSAEK” for grafts ≤50 μm. The described nomogram allows for standardized creation of NT grafts with a low tissue loss rate. This technique is safe and does not result in significant ECC loss compared with UT-DSAEK and DMEK grafts. Further studies are necessary to corroborate the postsurgical results of NT grafts. (Source: Cornea)
Source: Cornea - March 31, 2018 Category: Opthalmology Tags: Techniques Source Type: research

Terrien Marginal Degeneration Complicated by a Corneoscleral Cyst
Conclusions: This is an interesting case highlighting the rare complication of corneoscleral cyst in a young patient with inflammatory TMD. Excision of the cyst with a corneal patch graft and amniotic membrane grafting without any chemical cautery is effective in preventing recurrence. (Source: Cornea)
Source: Cornea - March 31, 2018 Category: Opthalmology Tags: Case Report Source Type: research

Recognition of Fungal Keratitis in Boston Type I Keratoprosthesis: Importance of Awareness and Novel Identification of Exophiala phaeomuriformis
Conclusions: Although fungal infiltration after KPro placement does not represent a novel clinical infection, identification of the rare Exophiala species in a patient with a KPro has not been reported and provides an opportunity for reflection on fungal identification, prophylaxis, and prevention in this vulnerable patient population. (Source: Cornea)
Source: Cornea - March 31, 2018 Category: Opthalmology Tags: Case Report Source Type: research

Clinically Significant Enhancement of Voriconazole Efficacy by Moxifloxacin and Gentamicin in Fungal Keratitis
Conclusions: In a subset of patients with fungal keratitis, the addition of topical moxifloxacin 0.3% or moxifloxacin 0.3% and gentamicin 0.3% may enhance the therapeutic effect of topical voriconazole 1%. (Source: Cornea)
Source: Cornea - March 31, 2018 Category: Opthalmology Tags: Case Report Source Type: research

Corneal Neurotization With a Great Auricular Nerve Graft: Effective Reinnervation Demonstrated by In Vivo Confocal Microscopy
Conclusions: Corneal neurotization leads to reinnervation of the cornea and recovery of ocular sensation in adults. The GAN is suitable for use in corneal neurotization because of its anatomical proximity and the low level of associated morbidity. Confocal microscopy demonstrated the occurrence of corneal reinnervation, which preceded the recovery of corneal sensation. (Source: Cornea)
Source: Cornea - March 31, 2018 Category: Opthalmology Tags: Case Report Source Type: research

Corneal Neurotization for Neurotrophic Keratopathy: Clinical Outcomes and In Vivo Confocal Microscopic and Histopathological Findings
Conclusions: Our study elucidates the mechanism of corneal neurotization surgery at a cellular level. Although only 1 patient achieved long-term improvement in corneal sensation postoperatively, the findings on IVCM and histopathological examination suggest that partial regeneration/maintenance of corneal nerves after corneal neurotization surgery is likely attributed to the paracrine neurotrophic support, instead of direct sprouting, from the perilimbal transplanted nerve fascicles. (Source: Cornea)
Source: Cornea - March 31, 2018 Category: Opthalmology Tags: Case Report Source Type: research

Involvement of Nectin–Afadin in the Adherens Junctions of the Corneal Endothelium
Conclusions: We believe this to be the first report of conservation of the nectin–afadin system in the corneal endothelium and its involvement in the formation of adherens junctions. N-cadherin, as a member of the cadherin family, is also essential for the formation and maintenance of cell–cell adhesion mediated by nectins and tight junctions in the corneal endothelium. (Source: Cornea)
Source: Cornea - March 31, 2018 Category: Opthalmology Tags: Basic Investigation Source Type: research

Reduction in Histone H3 Acetylation and Chromatin Remodeling in Corneas of Alloxan-Induced Diabetic Rats
Conclusions: The results of this study show that alloxan-induced diabetes altered the histone H3 acetylation pattern and compromised the chromatin supraorganization in corneal tissue/cells. Continued research is needed to understand the clinical and morphofunctional significance of changes in corneal cell nuclei of diabetic individuals. (Source: Cornea)
Source: Cornea - March 31, 2018 Category: Opthalmology Tags: Basic Investigation Source Type: research

Effects of 20% Human Serum on Corneal Epithelial Toxicity Induced by Benzalkonium Chloride: In Vitro and Clinical Studies
Conclusions: Data demonstrate that 20% human serum is effective in treating BAK-induced cytotoxicity in hCECs and provides a basis for using 20% autologous serum for patients with preservative-induced corneal epitheliopathy. (Source: Cornea)
Source: Cornea - March 31, 2018 Category: Opthalmology Tags: Basic Investigation Source Type: research

Collagen-Based Fillers as Alternatives to Cyanoacrylate Glue for the Sealing of Large Corneal Perforations
Conclusions: An ab interno patch system using CLP-PEG hydrogels designed to promote corneal tissue regeneration may be a viable alternative to conventional cyanoacrylate glue patching for the treatment of corneal perforation. Further experimentation and material refinement is required in advance of clinical trials. (Source: Cornea)
Source: Cornea - March 31, 2018 Category: Opthalmology Tags: Basic Investigation Source Type: research

Assessment of Glaucomatous Damage After Boston Keratoprosthesis Implantation Based on Digital Planimetric Quantification of Visual Fields and Optic Nerve Head Imaging
Conclusions: Clinicians should strive to vigilantly monitor for glaucoma despite the inherent difficulties in tonometry, optic nerve visualization and imaging, and visual field testing in KPro patients. Meticulous glaucoma surveillance with structural and functional testing combined with earlier IOP-lowering surgical intervention may result in decreased rates of glaucomatous vision loss in KPro patients. (Source: Cornea)
Source: Cornea - March 31, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Effects of Repeated Intravitreal Aflibercept Injection on the Corneal Endothelium in Patients With Age-Related Macular Degeneration: Outcomes From the RE-VIEW Study
Conclusions: Repeated IAI for 52 weeks had no apparent corneal endothelial toxicity noted on specular microscopy in patients treated for neovascular age-related macular degeneration. (Source: Cornea)
Source: Cornea - March 31, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Corneal Endothelial Tolerance After Iris-Fixated Phakic Intraocular Lens Implantation: A Model to Predict Endothelial Cell Survival
Conclusions: pIOL implantation is a safe surgical means to correct high myopia in phakic patients without compromising corneal endothelium survival. (Source: Cornea)
Source: Cornea - March 31, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Correlation Between Postoperative Central Corneal Thickness and Endothelial Damage After Cataract Surgery by Phacoemulsification
Purpose: To study the correlation between postoperative corneal edema and endothelial cell loss after cataract surgery by microcoaxial phacoemulsification. Methods: Eighty-five eyes of 85 consecutive patients with mild cataract (up to C5, N4, and P5: per LOCS III classification) were included in a prospective study from September 2014 to November 2014. Eighty-five eyes were necessary to obtain a precision of 0.15 for computation of the Pearson correlation coefficient. Pachymetry and endothelial cell density measurements were taken preoperatively, 2 hours after surgery, and 4 days, 15 days, and 1 month after surgery us...
Source: Cornea - March 31, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

An Early Finding of Keratoconus: Increase in Corneal Densitometry
Purpose: To investigate the corneal densitometry in subclinical keratoconus with normal elevation and pachymetric parameters. Methods: Patients with clinical keratoconus in one eye and subclinical keratoconus in the fellow eye were identified. The study group was selected from patients with subclinical keratoconus who showed normal results from topographic and Belin-Ambrósio Enhanced Ectasia Display III (BAD) analysis (Kmean (Source: Cornea)
Source: Cornea - March 31, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Additional Intrastromal Corneal Ring Segments in Keratoconus
Conclusions: KeraRing implantation in properly selected eyes with previously implanted INTACS could enhance final visual and refractive outcomes. (Source: Cornea)
Source: Cornea - March 31, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Visibility and Depth of the Stromal Demarcation Line After Corneal Collagen Cross-Linking Using Anterior Segment Optical Coherence Tomography: Comparison Between Isoosmolar and Hypoosmolar Riboflavin
Conclusions: The use of isoosmolar or hypoosmolar riboflavin does not significantly modify the depth or visibility of the stromal DL 1 month after accelerated CXL on AS-OCT evaluation. (Source: Cornea)
Source: Cornea - March 31, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Corneal Collagen Cross-Linking With Riboflavin and Ultraviolet A Light for Pediatric Keratoconus: Ten-Year Results
Conclusions: The study demonstrates the ability of CXL to slow down KC progression in pediatric patients, improving functional performance. Long-term stability may be correlated with CXL-induced delay in corneal collagen turnover and with spontaneous age-related KC stabilization. A 24% regression rate could be contemplated in the patients who were aged 15 years and younger at the time of inclusion in the treatment protocol. (Source: Cornea)
Source: Cornea - March 31, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research