Reply
No abstract available (Source: Cornea)
Source: Cornea - February 5, 2019 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Response to “Descemet Membrane Endothelial Keratoplasty for Failed Penetrating Keratoplasty: Visual Outcomes and Graft Survival”
No abstract available (Source: Cornea)
Source: Cornea - February 5, 2019 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Comparison of Tri-folded and Scroll-based Graft Viability in Preloaded Descemet Membrane Endothelial Keratoplasty
Conclusions: All techniques used resulted in clinically acceptable levels of ECL. Tri-folded tissue in a plastic cartridge did not result in ECL inferior to a scroll when prepared either immediately or preloaded for 48 hours. (Source: Cornea)
Source: Cornea - February 5, 2019 Category: Opthalmology Tags: Techniques Source Type: research

Femtosecond Laser-Assisted Deep Lamellar Descemet Membrane Endothelial Keratoplasty for the Treatment of Endothelial Dysfunction Associated With Posterior Stromal Scarring
Conclusions: As long as the anterior and mid-stroma are unaffected, those with endothelial diseases associated with opacification of the posterior stroma can benefit from endothelial keratoplasty through a Femto-DL-DMEK procedure, avoiding all well-known drawbacks of penetrating keratoplasty. (Source: Cornea)
Source: Cornea - February 5, 2019 Category: Opthalmology Tags: Case Report Source Type: research

Conjunctival Colloid Milium
Conclusions: Adult periocular colloid milium is an unusual presentation of a rare cutaneous deposition disease. The occurrence of conjunctival colloid milium is rare, and we report this case to increase knowledge and management regarding this rare disease and to differentiate it from other diseases such as amyloidosis, lipoid proteinosis, plasmacytoma, and conjunctival lymphoma, which carry a graver prognosis, and have a similar clinical appearance and can be distinguished only on the basis of histopathological characteristics. (Source: Cornea)
Source: Cornea - February 5, 2019 Category: Opthalmology Tags: Case Report Source Type: research

Bilateral Ulcerative Keratitis Associated With Afatinib Treatment for Non–Small-cell Lung Carcinoma
Conclusions: To the best of our knowledge, this is the first case in the literature that reports afatinib-related ulcerative keratitis. Careful monitoring for signs of ocular adverse events is recommended during treatment with afatinib for non–small-cell lung carcinoma. (Source: Cornea)
Source: Cornea - February 5, 2019 Category: Opthalmology Tags: Case Report Source Type: research

Ocular and Genetic Characteristics Observed in Two Cases of Fish-Eye Disease
Conclusions: Although it is a rare genetic disorder, FED should be considered in the differential diagnosis of corneal clouding. Corneal lipid deposits, visible on AS-OCT are suggestive of FED, and genetic analysis can be used to confirm the clinical diagnosis. Finally, there may be a relationship between dry eye disease and LCAT enzyme deficiency disorders, which should be investigated in further studies. (Source: Cornea)
Source: Cornea - February 5, 2019 Category: Opthalmology Tags: Case Report Source Type: research

Deep Anterior Lamellar Keratoplasty in a Case of Hurler–Scheie Syndrome Undergoing Enzyme Replacement Therapy
Conclusions: The present case highlights the possible effectiveness of DALK in patients with mucopolysaccharidosis (MPS)-related corneal stromal opacification, treated with ERT. (Source: Cornea)
Source: Cornea - February 5, 2019 Category: Opthalmology Tags: Case Report Source Type: research

Global Consensus on Definition, Classification, Diagnosis, and Staging of Limbal Stem Cell Deficiency
Conclusions: This global consensus provides a comprehensive framework for the definition, classification, diagnosis, and staging of LSCD. The newly established criteria will aid in the correct diagnosis and formulation of an appropriate treatment for different stages of LSCD, which will facilitate a better understanding of the condition and help with clinical management, research, and clinical trials in this area. (Source: Cornea)
Source: Cornea - February 5, 2019 Category: Opthalmology Tags: Special Article Source Type: research

Evaluation of Patent Blue as the Vital Dye in an Animal Model of Descemet Membrane Endothelial Keratoplasty
Conclusions: PB at 0.5% to 1.0% is biocompatible and can stain the graft sufficiently, making it an alternative for DMEK surgery. (Source: Cornea)
Source: Cornea - February 5, 2019 Category: Opthalmology Tags: Basic Investigation Source Type: research

Topical Rho-Associated Kinase Inhibitor, Y27632, Accelerates Corneal Endothelial Regeneration in a Canine Cryoinjury Model
Conclusions: Canine corneal endothelial function recovers at a similar rate as NHPs but more slowly than rabbits after cryoinjury. Faster corneal endothelial wound healing was observed by in vivo confocal microscopy and FD-OCT in dogs treated with Y27632 versus vehicle controls. Thus, a canine cryoinjury model may be a useful alternative to NHPs in detecting a response to therapies directed at endothelial regeneration. (Source: Cornea)
Source: Cornea - February 5, 2019 Category: Opthalmology Tags: Basic Investigation Source Type: research

Thymic Stromal Lymphopoietin-Related Allergic Pathway in Patients With Vernal Keratoconjunctivitis
Purpose: To investigate the expression of thymic stromal lymphopoietin (TSLP) and the relevant signaling pathways in the giant papillae obtained from patients with vernal keratoconjunctivitis (VKC) and to study the potential functional role and molecular mechanism of TSLP. Methods: Giant papillae from VKC patients and control samples were used to perform immunohistochemical staining and analyze the mRNA expression of TSLP and related pathway by real-time polymerase chain reaction. Results: TSLP was markedly expressed in the epithelial cells and some inflammatory cells of giant papillae, but not in the control conju...
Source: Cornea - February 5, 2019 Category: Opthalmology Tags: Basic Investigation Source Type: research

Late-Onset Sterile Peripheral Ulcerative Keratitis Post-Corneal Collagen Crosslinking
Conclusions: PUK is a rare but serious complication after CXL. Long-term follow-up is necessary to detect late-onset PUK. It is a treatable condition associated with older age and autoimmune conditions but has a good visual outcome. (Source: Cornea)
Source: Cornea - February 5, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Imaging Kayser-Fleischer Ring in Wilson Disease Using In Vivo Confocal Microscopy
Conclusions: IVCM images can be used as an objective clinical diagnostic tool to facilitate the identification of K-F rings and the diagnosis of WD. (Source: Cornea)
Source: Cornea - February 5, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Corneal Endothelial Cell Density and Morphology After Phacoemulsification in Patients With Primary Open-Angle Glaucoma and Cataracts: 2-Year Results of a Randomized Multicenter Trial
Purpose: To evaluate corneal endothelial cell density (ECD) and morphology 2 years after phacoemulsification in subjects from the COMPASS trial (ClinicalTrials.gov, NCT01085357) who had mild-to-moderate primary open-angle glaucoma and visually significant cataracts. Methods: The central corneal endothelium was evaluated by serial specular microscopy at 0 to 24 months. ECD, coefficient of variation, and percentage of hexagonal cells were evaluated by a central image analysis reading center and central corneal thickness (CCT) was evaluated by ultrasound pachymetry. Results: Of 131 subjects who underwent routine phaco...
Source: Cornea - February 5, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Relationship Between Ocular Surface Epithelial Damage, Tear Abnormalities, and Blink in Patients With Dry Eye
This study involved 45 eyes of 45 female patients with dry eye (mean age: 57.6 years). In all eyes, tear meniscus radius (mm), spread grade of the tear film lipid layer (SG: 1-5: 1 being the best), fluorescein breakup time (FBUT, seconds), corneal and bulbar conjunctival epithelial damage (CED: 15 points maximum and CONJUNCTIVAL EPITHELIAL DAMAGE (CjED): 6 points maximum, respectively), and Schirmer I test (ST1, mm) were evaluated. Blink rate (BR, blinks per minute), palpebral aperture height (mm), upper-eyelid opening-phase amplitude/upper-eyelid closing-phase amplitude (mm), upper-eyelid opening-phase duration/upper-eyel...
Source: Cornea - February 5, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Association Between Sleep Quality, Mood Status, and Ocular Surface Characteristics in Patients With Dry Eye Disease
Purpose: To evaluate sleep and mood status in patients with dry eye disease (DED) and analyze the association between sleep quality, mood status, and ocular surface characteristics. Methods: Consecutive patients with DED (N = 106) and age- and sex-matched healthy controls (N = 50) were enrolled. Tear fluid break up time (TBUT), corneal fluorescein staining, and Schirmer I tests were performed in the order listed here to evaluate dry eye. A visual analog scale was used to assess dry eye symptom severity. All subjects also completed the Pittsburgh Sleep Quality Index (PSQI, scores ≥5.5 indicated poor sleep), Patient ...
Source: Cornea - February 5, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Vitamin D Enhances the Efficacy of Topical Artificial Tears in Patients With Dry Eye Disease
Purpose: To investigate the efficacy of topical carbomer-based lipid-containing artificial tears (CLAT) and hyaluronate (HU) in patients with dry eye disease (DED) based on serum 25-hydroxyvitamin D (25HD) levels and cholecalciferol (vitamin D) supplementation. Methods: A total of 116 patients with DED from June 2015 to June 2016 were included. The participants were divided into the vitamin D deficiency (VDD) group and the non-VDD group according to their serum 25HD levels. The patients determined the ways of cholecalciferol supplementation. Ocular Surface Disease Index (OSDI) score, visual analog pain scale score, li...
Source: Cornea - February 5, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Direct and Indirect Flap Measurements in Femtosecond Laser–Assisted In Situ Keratomileusis
Purpose: To compare direct and indirect LASIK flap thickness measurements using ultrasound and Scheimpflug technology. Methods: Eighty-two eyes treated with laser-assisted in situ keratomileusis refractive surgery using a femtosecond laser (IntraLase FS150) were prospectively included in the study. Flap thickness was set to 115 μm. Corneal flap thickness was measured using the direct method—ie, ultrasound pachymetry immediately after flap construction in the presence of cavitation bubbles—and indirect methods, with subtraction of intraoperative post-lift corneal thickness measured using ultrasound pachy...
Source: Cornea - February 5, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Comparison of Corneal Epithelial Remodeling Over 2 Years in LASIK Versus SMILE: A Contralateral Eye Study
Conclusions: Both LASIK and SMILE resulted in significant epithelial thickening. This response seemed to be surprisingly quite similar between the 2 different techniques. This study suggests that epithelial remodeling may correlate with relative curvature changes resulting after both techniques, rather than the obvious difference of subepithelial corneal denervation changes. (Source: Cornea)
Source: Cornea - February 5, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Wavefront-Guided Photorefractive Keratectomy in the Treatment of High Astigmatism Following Keratoplasty
Purpose: To report the outcome of wavefront-guided photorefractive keratectomy (WG-PRK) in the treatment of high astigmatism following keratoplasty. Methods: A retrospective, interventional analysis including patients with high astigmatism following either penetrating keratoplasty or deep anterior lamellar keratoplasty, who underwent WG-PRK. Results: Thirteen eyes (7 right eyes) of 12 patients (10 male) aged 35.1 ± 5.9 years were included. Preoperative astigmatism ranged between 3.00 and 5.00 D. Average follow-up time was 14.0 ± 6.2 months. Uncorrected distance visual acuity (UDVA) improved from 0.97 ...
Source: Cornea - February 5, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Descemet Membrane Endothelial Keratoplasty After Failed Penetrating Keratoplasty
Purpose: To demonstrate the feasibility of Descemet membrane endothelial keratoplasty (DMEK) performed after previous penetrating keratoplasty (PK) failure and to describe primary outcomes. Methods: Twenty-eight eyes of 28 patients who underwent DMEK after primary PK failure between January 2013 and November 2017 were included in this single-center retrospective study. Best spectacle-corrected visual acuity, endothelial cell density, and the recipient's central corneal thickness were recorded preoperatively and at 1, 3, and 6 months after surgery. Results: The main indications for primary PK were keratoconus (32%),...
Source: Cornea - February 5, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Cannula-Assisted Technique to Unfold Grafts in Descemet Membrane Endothelial Keratoplasty
This study is a retrospective, comparative, nonrandomized, interventional case series that includes 143 DMEKs performed between February 2014 and November 2015. All eyes were divided into 2 groups: in one group, there were 48 cases that underwent DMEK using tap techniques only (Tapping DMEK group), and in another group, there were 30 cases in which irrigating cannulas were used to unfold the graft as a secondary approach (Cannula DMEK group). Intraocular manipulation time and total graft manipulation time were assessed. Uncorrected visual acuity, best spectacle-corrected visual acuity, and endothelial cell count were evalu...
Source: Cornea - February 5, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Association of Iris Damage With Reduction in Corneal Endothelial Cell Density After Penetrating Keratoplasty
Purpose: To evaluate the effect of iris damage on endothelial cell loss in the early phase after penetrating keratoplasty (PKP). Methods: This prospective consecutive study included 74 patients who underwent PKP without graft rejection during the follow-up period. Endothelial cell density (ECD) was measured using specular microscopy at 1, 3, 6, and 12 months after PKP. Iris damage scores (IDSs) were determined on the basis of slit-lamp microscopy or anterior segment optical coherence tomography imaging. Graft survival rates were compared among the different IDSs. Using multivariate analysis, the factors influencing po...
Source: Cornea - February 5, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Reports of Post-keratoplasty Infections for Eye Bank-prepared and Non–Eye Bank-prepared Corneas: 12 Years of Data From a Single Eye Bank
Conclusions: Reports of infections remained low despite increased use of eye bank-prepared tissue. These results suggest that factors other than eye bank tissue preparation should be considered when investigating potential sources of pathogen contamination in donor corneas. (Source: Cornea)
Source: Cornea - February 5, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Reply
No abstract available (Source: Cornea)
Source: Cornea - January 8, 2019 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Anterior Segment Complications Associated With the Live Herpes Zoster Vaccine
No abstract available (Source: Cornea)
Source: Cornea - January 8, 2019 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Multicenter Study of Intense Pulsed Light Therapy for Patients With Refractory Meibomian Gland Dysfunction
No abstract available (Source: Cornea)
Source: Cornea - January 8, 2019 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Reply
No abstract available (Source: Cornea)
Source: Cornea - January 8, 2019 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Response to “Central Corneal Thickness Evaluation in Diabetic Peripheral Neuropathy”
No abstract available (Source: Cornea)
Source: Cornea - January 8, 2019 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Repeatability of Meibomian Gland Contrast, a Potential Indicator of Meibomian Gland Function
Conclusions: Meibomian gland contrast is a repeatable and reliable measure for changes in Meibomian gland contrast greater than 11 in the UL and 18 in the LL. (Source: Cornea)
Source: Cornea - January 8, 2019 Category: Opthalmology Tags: Techniques Source Type: research

“Ghost DMEK” Technique: Circular Peripheral Staining of Descemet's Membrane Endothelial Keratoplasty Grafts
Conclusions: Peripheral staining of DMEK grafts (ghost DMEK) is a simple and effective method for graft visualization in the anterior chamber, obviating the need for trypan blue staining and other techniques and devices currently used for the identification of graft orientation and folding status, thus simplifying and shortening surgery. (Source: Cornea)
Source: Cornea - January 8, 2019 Category: Opthalmology Tags: Techniques Source Type: research

Secukinumab-Associated Crystalline Corneal Deposition
Conclusions: To the best of the authors' knowledge, this is the first report of corneal crystal deposition attributed to secukinumab. The number of monoclonal antibodies in use across multiple medical disciplines is increasing, and corneal specialists may see this presentation more frequently in the future. These drugs provide critical disease-modifying treatment to patients with debilitating systemic pathology. It is important that we understand the natural history of their side effects to allow their full utilization. (Source: Cornea)
Source: Cornea - January 8, 2019 Category: Opthalmology Tags: Case Report Source Type: research

Capnocytophaga Keratitis: Clinical Presentation and Use of Metagenomic Deep Sequencing for Diagnosis
Conclusions: Capnocytophaga is a rare and aggressive infection. Even when traditional culture identifies the pathogen rapidly, keratitis can progress to perforation. In cases of severe keratitis in which traditional culture methods are unrevealing, metagenomic deep sequencing has potential to provide actionable diagnoses. (Source: Cornea)
Source: Cornea - January 8, 2019 Category: Opthalmology Tags: Case Report Source Type: research

Combined Keratectomy and Localized Limbal Cauterization for Treating Lisch Epithelial Corneal Dystrophy
Conclusions: Simple epitheliectomy combined with focal cauterization of the limbal focus of origin can be a simple, safe, and minimally invasive option for treatment of LECD. (Source: Cornea)
Source: Cornea - January 8, 2019 Category: Opthalmology Tags: Case Report Source Type: research

Efficacy of Luliconazole Against Broad-Range Filamentous Fungi Including Fusarium solani Species Complex Causing Fungal Keratitis
Conclusions: LLCZ has the strongest in vitro antifungal activity among all drugs used against broad-range filamentous fungi including FSSC. LLCZ may potentially be a new medical treatment option for fungal keratitis. (Source: Cornea)
Source: Cornea - January 8, 2019 Category: Opthalmology Tags: Basic Investigation Source Type: research

Minimizing Endothelial Cell Loss Caused by Orientation Stamps on Preloaded Descemet Membrane Endothelial Keratoplasty Grafts
Conclusions: Loss of endothelial cells associated with graft-stamping was greater in preloaded tissue than in prestripped tissue and was less with a smaller F-stamp than with a larger S-stamp. Using a smaller stamp could help minimize ECL in prestripped and preloaded DMEK grafts. (Source: Cornea)
Source: Cornea - January 8, 2019 Category: Opthalmology Tags: Basic Investigation Source Type: research

Ocular Toxicity of Mirvetuximab
Conclusions: Mirvetuximab soravtansine therapy can cause transient corneal toxicity. A short course of topical steroids can reduce the patient symptoms. (Source: Cornea)
Source: Cornea - January 8, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Tear Meniscus and Corneal Sub-basal Nerve Plexus Assessment in Primary Sjögren Syndrome and Sicca Syndrome Patients
Purpose: To evaluate lower tear meniscus and corneal sub-basal nerve plexus in primary Sjögren's syndrome (pSS) and Sicca syndrome patients. Methods: Cross-sectional study of 116 patients with Sicca syndrome associated with pSS and not associated with Sjögren's syndrome (non-SS Sicca) and 20 normal control subjects. Tear meniscus height and area were measured using anterior segment optical coherence tomography; corneal sub-basal nerve plexus density, length, and tortuosity were evaluated using in vivo confocal microscopy. Data analysis was performed using IBM-SPSS Statistics 24.0. Results: Corneal sub-bas...
Source: Cornea - January 8, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Vault Changes Caused by Light-Induced Pupil Constriction and Accommodation in Eyes With an Implantable Collamer Lens
Purpose: An appropriate vault after implantation of a posterior chamber phakic intraocular lens with a central hole (ICL KS-AP) is important for successful long-term outcomes. In the present study, we used anterior segment optical coherence tomography (AS-OCT) to examine dynamic pupil and vault changes under photopic and scotopic conditions and during accommodation in eyes with ICL KS-AP. Methods: This retrospective study included patients at an outpatient ophthalmology clinic who underwent ICL KS-AP implantation>1 month before enrollment. All patients underwent dynamic AS-OCT imaging under photopic and scotopic co...
Source: Cornea - January 8, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Evaluation of Autologous Blood in Pterygium Surgery With Conjunctival Autograft
Purpose: Autologous blood has been used exploratively with conjunctival autograft in pterygium surgery. However, it is controversial whether autologous blood performed better than other fixation methods, including fibrin glue and sutures. This meta-analysis was conducted to evaluate the effectiveness of using autologous blood in pterygium surgery with conjunctival autograft. Methods: The study was conducted according to the PRISMA guidelines. The MEDLINE, Cochrane library, and Embase databases were systematically searched from their establishment until April 1, 2018. Randomized controlled trials comparing autologous b...
Source: Cornea - January 8, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Randomized Study of Collagen Cross-Linking With Conventional Versus Accelerated UVA Irradiation Using Riboflavin With Hydroxypropyl Methylcellulose: Two-Year Results
Conclusions: Improvement in visual acuity and maximum keratometric reading 2 years after CXL was found after both conventional and accelerated UVA irradiation using methylcellulose–riboflavin. This suggests that when using riboflavin with methylcellulose, the less time-consuming accelerated protocol is a valuable and effective option in CXL treatment. (Source: Cornea)
Source: Cornea - January 8, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Scleral Ischemia in Acute Ocular Chemical Injury: Long-Term Impact on Rehabilitation With Limbal Stem Cell Therapy
Conclusions: The presence and extent of scleral ischemia are important prognostic factors when assessing recovery in eyes with acute chemical injury. The authors recommend that it be added as a poor prognostic indicator in the existing classifications of acute chemical injury. (Source: Cornea)
Source: Cornea - January 8, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Evaluation of Big Bubble Technique for Deep Anterior Lamellar Keratoplasty in Patients With Radial Keratotomy
Conclusions: In eyes that underwent prior RK, DALK by manual dissection should be considered as a preferable surgical technique. (Source: Cornea)
Source: Cornea - January 8, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Management of Type 2 Bubble Formed During Big Bubble Deep Anterior Lamellar Keratoplasty
Conclusions: DM baring techniques should be avoided in eyes with type 2 BB. Instead, deep stromal dissection searching for an incomplete type 1 bubble or using one of the manual dissection techniques as a guide to the clear pre-Descemetic stroma is safer and more reliable. (Source: Cornea)
Source: Cornea - January 8, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Retrospective Single-Center Registry Study on Graft Thickness 1 Year After Descemet Stripping Automated Endothelial Keratoplasty
Purpose: To compare the graft thickness of eye bank precut grafts with graft thickness measured 1 year after Descemet stripping automated endothelial keratoplasty (DSAEK) and to correlate the graft thickness of eye bank precut grafts with best spectacle-corrected visual acuity (BSCVA) and endothelial cell density (ECD) 1 year after DSAEK. Methods: This was a retrospective registry study of 183 eyes of 179 DSAEK patients. Grafts were cut in the eye bank after 1 day in dextran-containing medium, and thickness was measured by optical coherence tomography immediately after precutting. Examinations 1 year after DSAEK inclu...
Source: Cornea - January 8, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

A Multicenter Study Evaluating the Risk Factors and Outcomes of Repeat Descemet Stripping Endothelial Keratoplasty
Conclusions: Repeating DSEK improves vision following failed or decompensated DSEK surgery. Higher preoperative repeat DSEK IOPs were associated with improved visual outcomes, and initial graft rebubble rates, which decreased over time, were likely due to surgeon experience. (Source: Cornea)
Source: Cornea - January 8, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Descemet Membrane Endothelial Keratoplasty (DMEK) Graft Dislocation Into the Vitreous Cavity
Conclusions: The risk of fibrous proliferation and retinal detachment after posterior dislocation of DMEK grafts may be less than in grafts including corneal stroma, but pars plana vitrectomy and retrieval of the dislocated corneal transplant are still indicated after revision corneal transplant surgery where visual symptoms or signs of fibrotic change around the dislocated graft are evident. (Source: Cornea)
Source: Cornea - January 8, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research

Influence of Intraoperative Air Tamponade Time on Graft Adherence in Descemet Membrane Endothelial Keratoplasty
Purpose: To study the influence of different intraoperative air tamponade times on graft adherence after Descemet membrane endothelial keratoplasty (DMEK). Methods: In this interventional case series, we evaluated 117 eyes with Fuchs endothelial corneal dystrophy (FECD) that underwent DMEK using intraoperative air tamponade times of 60 minutes (group I; n = 39), 45 minutes (group II; n = 39), or 30 minutes (group III; n = 39). At 1 and 6 months postoperatively, graft adherence status, endothelial cell density, central pachymetry, and postoperative complications were recorded. Results: At 1 month, 19 of the 117 eyes...
Source: Cornea - January 8, 2019 Category: Opthalmology Tags: Clinical Science Source Type: research