Corneal Cross-Linking: Current USA Status Report From the Cornea Society
Abstract: The initial published clinical report on riboflavin/ultraviolet A corneal cross-linking (CXL) for treatment of progressive keratoconus dates back to 2003. CXL has since then been widely used outside the United States for treatment of progressive keratoconus and post-laser in situ keratomileusis ectasia. The Food and Drug Administration (FDA) approved Avedro Inc.'s corneal cross-linking system (KXL) for treatment of patients with progressive keratoconus and post-laser in situ keratomileusis ectasia in April 2016. The procedure is not currently approved for stable keratoconus. There are 2 FDA-approved topical oph...
Source: Cornea - September 11, 2018 Category: Opthalmology Tags: Special Article Source Type: research

Human Corneal Changes After Rose Bengal Photodynamic Antimicrobial Therapy for Treatment of Fungal Keratitis
No abstract available (Source: Cornea)
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Letter to the Editor Source Type: research

Topical Tacrolimus as Adjuvant Therapy to Corticosteroids in Acute Endothelial Graft Rejection After Penetrating Keratoplasty: A Randomized Controlled Trial Erratum
No abstract available (Source: Cornea)
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Erratum Source Type: research

Comparative Image Atlas of Current and New Technologies in Corneal Donor Tissue Evaluation: Erratum
No abstract available (Source: Cornea)
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Erratum Source Type: research

Femtosecond Laser–Assisted Graft Preparation for Descemet Membrane Endothelial Keratoplasty
Conclusions: The femtosecond laser may be a useful adjunct in graft preparation for DMEK. (Source: Cornea)
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Techniques Source Type: research

Descemet Stripping Automated Endothelial Keratoplasty With a Retention Suture: Description of a Technique for Patients at High Risk of Graft Detachment
Conclusions: A cloverleaf or parallel retention suture in conjunction with Descemet stripping automated endothelial keratoplasty seems to reduce the risk of detachment in high-risk patients, while maintaining adequate cell density and graft clarity at 1 year. (Source: Cornea)
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Techniques Source Type: research

Novel Technique for Improving Graft Unfolding in Vitrectomized Eyes Using a Temporary Diaphragm in Descemet Membrane Endothelial Keratoplasty
Purpose: To describe a new surgical technique for performing Descemet membrane endothelial keratoplasty (DMEK) using a temporary hydrophilic methacrylate sheet in the anterior chamber in cases of previous vitrectomy with complete removal of the vitreous body. Methods: Medical records were reviewed for baseline and follow-up best spectacle-corrected visual acuity, endothelial cell count, and indication for DMEK using a temporary hydrophilic methacrylate sheet. Operative notes were analyzed in all cases to identify any specific intraoperative event. Results: Seven eyes of 7 patients were included in this analysis. Me...
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Techniques Source Type: research

Primary Modified Predescemetic Deep Anterior Lamellar Keratoplasty in Acute Corneal Hydrops
Conclusions: Primary pdDALK was possible as single-stage definitive treatment with early visual rehabilitation and avoidance of scarring in our case series. Simultaneous correction of pathology by closure of DM break, anatomical correction of ectasia and thinning, optical correction by improved corneal topography and by regaining corneal structure and transparency, and retention of host DM and endothelium are advantages. Advanced DALK surgeons may use this technique. (Source: Cornea)
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Case Report Source Type: research

Conjunctival Eosinophilic Masses With Chronic Eosinophilic Pneumonia
Conclusions: Based on the clinical course and histopathology, the conjunctival proliferative masses in our case were assumed to be associated with CEP. (Source: Cornea)
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Case Report Source Type: research

“Eye Dropping”—A Case Report of Transconjunctival Lysergic Acid Diethylamide Drug Abuse
Conclusions: To the best of our knowledge, this is the first reported case of bilateral hemorrhagic conjunctival abrasion and corneal abrasion secondary to LSD. “Kissing” conjunctival lesions, which have been previously reported with heroin use, should raise suspicion for drug abuse. (Source: Cornea)
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Case Report Source Type: research

Characterization of Corneal Donor Tissue Lesions by Anterior Segment Optical Coherence Tomography Compared With Eye Bank Technician Slit-Lamp Examination
Conclusions: Our study highlights both advantages and limitations of OCT compared with technician SLE in the evaluation of donor corneal tissue. Although OCT may miss some peripheral lesions and LASIK scars that are identifiable on SLE, OCT's depth resolution is helpful in differentiating whether shallow anterior opacities actually extend deeper into the stroma or are confined superficially to the epithelium. (Source: Cornea)
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Basic Investigation Source Type: research

Therapeutic Effects of Topical 8-Oxo-2’-deoxyguanosine on Ethanol-Induced Ocular Chemical Injury Models
Purpose: To evaluate the therapeutic effects of topical 8-oxo-2’-deoxyguanosine (8-oxo-dG) on experimental ocular chemical injury models. Methods: We created ocular chemical injury models with 8-week-old BALB/c mice (n = 70) by applying 100% ethanol; the mice were then treated with 8-oxo-dG eye drops 10 and 5 mg/mL and phosphate-buffered saline (PBS) twice daily. After 7 days, clinical findings such as corneal integrity, clarity, and neovascularization were assessed. Histology, immunohistochemistry findings, and inflammatory cytokine levels using real-time polymerase chain reactions in the corneas of the mice we...
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Basic Investigation Source Type: research

Association Between Advanced Keratoconus and Serum Levels of Zinc, Calcium, Magnesium, Iron, Copper, and Selenium
In this study, 50 patients with advanced KCN and 50 control subjects were included. Plasma levels of Zn, Ca, Mg, Fe, Cu, and Se were compared between the groups. Results: Mean ± SD age of the patients in the case and control groups was 29.3 ± 3.5 and 28.9 ± 5.9 years, respectively (P = 0.669). Among serum parameters, there were no statistically significant differences between the 2 groups in serum levels of Ca, Mg, and Fe (P> 0.05), whereas serum levels of Zn and Cu were significantly lower in the case group than the control group [65.92 ± 7.90 vs. 87.36 ± 13.64 μg/dL and 78.48 &...
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Basic Investigation Source Type: research

Clinical Outcomes After Implantation of 320°-Arc Length Intrastromal Corneal Ring Segments in Keratoconus
Purpose: To evaluate the clinical outcomes after implantation of a new 320°-arc length Ferrara intrastromal corneal ring segment (320-ICRS) in eyes of patients with keratoconus. Methods: A multicentric nonrandomized study was conducted in which a new 320-ICRS was placed in 138 eyes of 130 patients with keratoconus. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), keratometry, corneal volume, asphericity, lines of vision gain/loss, and vectorial analysis were assessed preoperatively and at the final follow-up visit after the procedure. Results: The mean follow-up time was 6.2 &...
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

High-Resolution Anterior Segment Optical Coherence Tomography in Intraepithelial Versus Invasive Ocular Surface Squamous Neoplasia
Conclusions: A visible clear plane of separation and increased thickness on ASOCT may serve as surrogate markers of intraepithelial OSSN and help differentiate it from invasive OSSN. (Source: Cornea)
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Conjunctival Squamous Neoplasia: Staging and Initial Treatment
Conclusions: The AJCC stage does not correlate with the initial treatment of CIN. The AJCC T3 category should be reviewed to differentiate diffuse SCCs with broad surface extension from tumors with deep scleral invasion. (Source: Cornea)
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Infrared Video Meibography of Lower Lid Meibomian Glands Shows Easily Distorted Glands: Implications for Longitudinal Assessment of Atrophy or Growth Using Lower Lid Meibography
Purpose: To evaluate measurement reliability of the meibomian gland (MG) tissue area during infrared video meibography (IR-VM) of the lower lid. Methods: This is a retrospective analysis, using ImageJ, of IR-VM of 17 lids of 11 consecutive patients (age 56.6 ± 15.9 years; 9 females and 2 males) focusing on the presence of a statistically significant variation of the MG tissue area and the MG tissue area relative to the total measurement field (TMF) secondary to inadvertent lid distortion and/or an altered vertical gaze direction during a single-image acquisition video sequence. Results: For lids with distort...
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Effect of the Meibomian Gland Squeezer for Treatment of Meibomian Gland Dysfunction
Purpose: To investigate the effect of the meibomian gland squeezer for treatment of meibomian gland dysfunction (MGD). Methods: Seventy patients (140 eyes) with MGD were randomly divided into 2 groups: 36 patients who were treated by the meibomian gland squeezer as the treatment group and 34 patients were selected as the control group. Patients were evaluated at baseline, and 2-week and 1-month visits for subjective symptoms, objective signs and pain assessments, including ocular symptom scores, Ocular Surface Disease Index, tear breakup time, corneal fluorescein staining, Schirmer scores with no anesthetic (Schirmer ...
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Meibomian Gland Dropout in Hematological Patients Before Hematopoietic Stem Cell Transplantation
Purpose: To perform qualitative and quantitative analysis of meibomian gland (MG) dropout in hematological patients before hematopoietic stem cell transplantation (HSCT) and to correlate it with both ocular surface and hematological characteristics. Methods: This prospective study included 46 consecutive patients undergoing HSCT and 30 age- and sex-matched healthy controls. Noninvasive meibography of the lower eyelid, meiboscore (Pult scale), Schirmer test type I, tear film breakup time, and corneal and conjunctival staining were measured. Subjective symptoms were scored by the Ocular Surface Disease Index. The dry ey...
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Development of the Modified Lenticule Edge Dissection Technique for Small Incision Lenticule Extraction
Conclusions: The modified lenticule edge dissection technique of SMILE is simpler and faster in identifying the correct dissection plane. It is efficient in reducing surgical manipulation, shortening the learning curve required for lenticule dissection, and allows surgeons to perform SMILE more safely and efficiently. (Source: Cornea)
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Moderately Long-Term Safety and Efficacy of Repeat Penetrating Keratoplasty
Conclusions: Repeat PK provided relatively safe and effective moderately long-term surgical outcomes. (Source: Cornea)
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Early Results of Penetrating Keratoplasty in Patients With Unilateral Chemical Injury After Simple Limbal Epithelial Transplantation
Conclusions: PKP was found to have a good outcome when the surface has been stabilized by SLET as an initial procedure in unilateral ocular chemical injury. The visual outcome was restricted mainly by other causes such as glaucoma and amblyopia. (Source: Cornea)
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Indications and Outcomes of Penetrating Keratoplasty in Infants and Children of Beijing, China
Purpose: To retrospectively investigate the indications and outcomes of pediatric penetrating keratoplasty (PKP) and to explore factors that affect graft survival. Methods: Patients who had undergone PKP from May 2010 to December 2016, aged ≤12 years were categorized as infants (≥3 months and (Source: Cornea)
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Visual Outcomes and Prognostic Factors of Successful Penetrating Keratoplasty in 0- to 7-Year-Old Children With Congenital Corneal Opacities
Conclusions: Most of the clear grafts after PK in children with congenital corneal opacities achieved ambulatory vision. The visual outcome was better in binocular opacity cases than in monocular ones. (Source: Cornea)
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Outcome of Human Donor Corneas Stored for More Than 4 Weeks
Conclusions: Corneas stored in organ culture for more than 4 weeks are equally suitable for DSAEK and PKP transplantation as corneas stored in organ culture for up to 4 weeks. (Source: Cornea)
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Comparison of Visual Acuity Outcomes Between Nanothin Descemet Stripping Automated Endothelial Keratoplasty and Descemet Membrane Endothelial Keratoplasty
Conclusions: Compared with DMEK, NT-DSAEK provides comparable visual outcomes and complications rates. (Source: Cornea)
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Corneal Cross-Linking: Current USA StatusReport From the Cornea Society
Abstract: The initial published clinical report on riboflavin/ultraviolet A corneal cross-linking (CXL) for treatment of progressive keratoconus dates back to 2003. CXL has since then been widely used outside the United States for treatment of progressive keratoconus and post-laser in situ keratomileusis ectasia. The Food and Drug Administration (FDA) approved Avedro Inc.'s corneal cross-linking system (KXL) for treatment of patients with progressive keratoconus and post-laser in situ keratomileusis ectasia in April 2016. The procedure is not currently approved for stable keratoconus. There are 2 FDA-approved topical oph...
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Special Article Source Type: research

The Barcelona Principles: An Agreement on the Use of Human Donated Tissue for Ocular Transplantation, Research, and Future Technologies©
Preamble The Barcelona Principles: An Agreement on the use of human donated tissue for ocular transplantation, research, and future technologies (Agreement) is a global bioethical framework (GBF), developed by the eye bank and ophthalmic communities, to inform on the management of altruistic and voluntary donations; their subsequent utility within ophthalmology and research; their retention as a public resource for the shared benefit of all; and their accessibility by waiting recipients. The Agreement is the result of global sector engagement over a 12-month period—led by the Global Alliance of Eye Bank Associatio...
Source: Cornea - September 8, 2018 Category: Opthalmology Tags: Special Article Source Type: research

Reply
No abstract available (Source: Cornea)
Source: Cornea - August 8, 2018 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Changes in Central Corneal Thickness With Corneal Collagen Cross-Linking
No abstract available (Source: Cornea)
Source: Cornea - August 8, 2018 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Interface Fungal Keratitis After Descemet Stripping Automated Endothelial Keratoplasty: A Review of the Literature With a Focus on Outcomes
Conclusions: Penetrating keratoplasty is frequently required to eliminate interface fungal infection after Descemet stripping automated EK. A satisfactory visual outcome is usually achieved. (Source: Cornea)
Source: Cornea - August 8, 2018 Category: Opthalmology Tags: Review Source Type: research

Etiology of Global Corneal Blindness and Current Practices of Corneal Transplantation: A Focused Review
Conclusions: Most corneal blindness worldwide is secondary to anterior corneal pathology because of infections and trauma. However, this does not align with the current trends and practices in the field of corneal transplantation. We discuss potential solutions to address the current leading causes of global corneal blindness, including increasing the number of anterior lamellar keratoplasties performed, using long-term preserved corneas by trained surgeons, and improving eye bank handling and distribution of procured tissues. (Source: Cornea)
Source: Cornea - August 8, 2018 Category: Opthalmology Tags: Review Source Type: research

Cincinnati Protocol for Preoperative Screening and Donor Selection for Ocular Surface Stem Cell Transplantation
Conclusions: Our protocol for OSST preoperative screening and donor selection minimizes the antigenic burden for transplanted tissue by selecting the best available donor match. (Source: Cornea)
Source: Cornea - August 8, 2018 Category: Opthalmology Tags: Techniques Source Type: research

Simulation Model for DMEK Donor Preparation
Conclusions: The described simulation model can assist surgeons and eye bank technicians to learn steps in donor preparation in DMEK. (Source: Cornea)
Source: Cornea - August 8, 2018 Category: Opthalmology Tags: Techniques Source Type: research

Double-Bubble Technique in Descemet Membrane Endothelial Keratoplasty for Vitrectomized Eyes: A Case Series
Conclusions: This technique (double bubble technique) enables safe and easy DMEK surgery, even in eyes that have been previously vitrectomized and IOL-sutured. Further clinical studies with a large number of patients exhibiting complex eyes are required to definitively establish the clinical value of this technique. (Source: Cornea)
Source: Cornea - August 8, 2018 Category: Opthalmology Tags: Techniques Source Type: research

Isolated Conjunctival Inflammation as a Manifestation of IgG4-Related Disease
Conclusions: Isolated conjunctival inflammation without orbital involvement can be a presentation of IgG4-RD. (Source: Cornea)
Source: Cornea - August 8, 2018 Category: Opthalmology Tags: Case Report Source Type: research

Sclerocornea–Microphthalmia–Aphakia Complex: Description of Two Additional Cases Associated With Novel FOXE3 Mutations and Review of the Literature
Conclusions: The sclerocornea–microphthalmia–aphakia complex is a severe malformative ocular phenotype resulting from mutations in the FOXE3 transcription factor. To date, patients from at least 14 families with this uncommon ocular disorder have been described. The identification of 2 novel pathogenic variants in our patients expands the mutational spectrum in FOXE3-related congenital eye disorders. In addition, we performed a review of the clinical and genotypic characteristics of all published patients carrying biallelic FOXE3 mutations. (Source: Cornea)
Source: Cornea - August 8, 2018 Category: Opthalmology Tags: Case Report Source Type: research

Limbal Stem Cell Deficiency Secondary to Diffuse Non-necrotizing Anterior Scleritis: A Clinicopathological Report
Conclusions: LSCD can be a rare complication of DNNAS. After control of ocular surface inflammation, autologous limbal stem cell grafting and amniotic membrane transplantation can be effective in normalizing the ocular surface. (Source: Cornea)
Source: Cornea - August 8, 2018 Category: Opthalmology Tags: Case Report Source Type: research

Validity and Reliability of a Novel Handheld Osmolarity System for Measurement of a National Institute of Standards Traceable Solution
Conclusions: The osmolarity system reliably and accurately measured the osmolarity of an NIST solution in a laboratory setting, using an adaptor to correct for differences in resistance between a laboratory NIST solution measurement and direct measurements on the palpebral conjunctiva of the eyelid. The handheld osmolarity system represents a rapid and accurate instrument for measurement of tear osmolarity in a simulated testing setting. (Source: Cornea)
Source: Cornea - August 8, 2018 Category: Opthalmology Tags: Basic Investigation Source Type: research

Designing Minimally Invasive Preocular Contact Tips for Potential Application in Tear Collection
Conclusions: The PCT proposed in this study can be a promising tool for minimally invasive collection of basal tears from the inferior palpebral conjunctiva. (Source: Cornea)
Source: Cornea - August 8, 2018 Category: Opthalmology Tags: Basic Investigation Source Type: research

Predictive Value of Corneal Donor Demographics on Endothelial Cell Density
Purpose: Corneal endothelial cell density (ECD) is an important measure for determining suitability for transplantation. Although age has been correlated with ECD, the impact of sex and ethnicity is unclear. Methods: Corneal donor information from SightLife Eye Bank was collected between 2012 and 2016. Tests of association were adjusted for covariates using linear regression including age, race, and sex. “Unsuitable for transplantation” was a label assigned to specimens with extensive cell dropout, ECD (Source: Cornea)
Source: Cornea - August 8, 2018 Category: Opthalmology Tags: Basic Investigation Source Type: research

Outcomes of Thermal Pulsation Treatment for Dry Eye Syndrome in Patients With Sjogren Disease
Purpose: To evaluate the clinical outcomes of thermal pulsation treatment in patients with meibomian gland dysfunction (MGD) and dry eye secondary to Sjogren disease. Methods: Twenty-four eyes from 13 patients with previously diagnosed Sjogren disease who presented to our institution with dry eye symptoms and had thermal pulsation treatment were prospectively followed up. Patients underwent comprehensive slit-lamp examination, including MGD grading, gland oil flow, corneal and conjunctival staining scores, and tear break-up time (TBUT). Tear osmolarity was tested before and after treatment. Results: The average pat...
Source: Cornea - August 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Ocular Surface Findings in Patients With Lichen Planopilaris
Conclusions: Patients with LPP, scored worse in ocular surface tests. This finding warrants special scrutiny for dry eye and MG dysfunction in these patients. (Source: Cornea)
Source: Cornea - August 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Evaluation of the Effectiveness of Cross-Linking Combined With Photorefractive Keratectomy for Treatment of Keratoconus
Conclusions: CXL Plus improved the refractive status of keratoconus during 18 months of follow-up, despite its potential early postoperative complications of delayed epithelial healing and corneal haze. CXL Plus reduced the myopic component more than the astigmatic component of keratoconus. However, the safety and stability of the procedure were offset by longer-term postoperative complications and a high rate of postoperative progression of keratoconus. (Source: Cornea)
Source: Cornea - August 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Central Corneal Thickness Increase Due to Stromal Thickening With Diabetic Peripheral Neuropathy Severity
Conclusions: This study demonstrates that CCT increases with DPN severity because of an increase in stromal thickness. CCT increase associated with DPN has important clinical implications including glaucoma progression, keratoconus susceptibility, and intraocular pressure assessment and should be accounted for when evaluating patients with diabetes. (Source: Cornea)
Source: Cornea - August 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Corneal Subbasal Nerve Density and Sensitivity After Pars Plana Vitrectomy Using Contact or Noncontact Wide-Angle Viewing Systems
Purpose: To assess corneal subbasal nerve density (SBND) and corneal sensitivity (CS) after pars plana vitrectomy (PPV) for rhegmatogenous retinal detachment (RRD) without intraoperative 360-degree laser treatment using contact or noncontact panoramic viewing systems. Methods: This is a prospective study of 34 eyes affected by RRD, which underwent PPV using contact (18 eyes) and noncontact (16 eyes) panoramic viewing systems; 12 eyes which underwent scleral buckling, and 17 eyes which underwent cataract surgery. SBND and CS were assessed before surgery and 3 and 6 months postoperatively by in vivo confocal microscopy ...
Source: Cornea - August 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Risk Factors for Sporadic Diffuse Lamellar Keratitis After Microkeratome Laser-Assisted In Situ Keratomileusis: A Retrospective Large Database Analysis
Purpose: To determine the factors associated with sporadic diffuse lamellar keratitis (DLK) after microkeratome laser-assisted in situ keratomileusis (LASIK). Methods: This large database retrospective study included consecutive cases of LASIK performed between 2007 and 2016 at Care-Vision Laser Centers, Tel-Aviv, Israel. Patients were divided into 2 groups according to whether or not they subsequently developed DLK. Results: A total of 24,026 eyes of 12,013 patients with a mean age of 32.9 ± 10.3 years were included. Post-LASIK DLK developed in 464 eyes (1.9%), and the annual rate decreased from 7.1% (2007)...
Source: Cornea - August 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Incidence, Indications, and Outcomes of Eyes Needing Early Flap Lifting After LASIK
Purpose: To analyze the incidence, indications, and outcomes associated with early flap relifting after uncomplicated laser in situ keratomileusis (LASIK). Methods: All LASIK cases from a single surgical center between 2007 and 2015 were reviewed. Early postoperative flap lift cases ( (Source: Cornea)
Source: Cornea - August 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Functional Optical Zone After Small-Incision Lenticule Extraction as Stratified by Attempted Correction and Optical Zone
Purpose: To compare the functional optical zone (OZ) with different levels of myopia and different OZ groups after small-incision lenticule extraction. Methods: This retrospective study included 249 patients (120 men) after small-incision lenticule extraction correction. We grouped participants according to attempted correction [low: spherical equivalent (SE)> −3.0 D; moderate: −6.0 D ≥ SE ≥ −3.0 D; high: SE ≥ −6.0 D] and planned functional optical zone (PFOZ) (OZ-1: PFOZ ≤ 6.3 mm; OZ-2: 6.3 mm 6.5 mm), and we compared the achieved functional optical zone (AFOZ) and total corneal...
Source: Cornea - August 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research

Incidence and Outcomes of Positive Donor Rim Cultures and Infections in the Cornea Preservation Time Study
Conclusions: A longer preservation time was not associated with a higher rate of positive donor rim cultures. The overall rate of infection across the entire cohort was low. (Source: Cornea)
Source: Cornea - August 8, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research