Inadvertent Injection of Botox Into the Anterior Chamber of the Eye With Crystalline Deposition
No abstract available (Source: Cornea)
Source: Cornea - December 6, 2022 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Clinically Based Automated Tracing and Tortuosity Estimation of Corneal Nerve Fibers From Confocal Microscopy Images
Conclusions: The proposed framework provides completely automated analysis of corneal nerve images. The results demonstrate the ability of our method to emulate the clinical classification of tortuosity levels and its potential for identifying healthy and pathological subjects. (Source: Cornea)
Source: Cornea - December 6, 2022 Category: Opthalmology Tags: Techniques Source Type: research

Sural Nerve Vertical Cross-Face Graft for Lacrimal Gland Neurotization to Improve Tear Secretion in Neurodeprivative Dry Eye
Conclusions: Vertical cross-face using a sural nerve graft to connect the lacrimal gland with the contralateral submandibular gland is a novel technique for treating patients with facial nerve palsy and severe neurodeprivative dry eye disease. This surgery both performed alone and combined with corneal neurotization is able to improve tear secretion and decrease the need for frequent instillations of tear substitutes. (Source: Cornea)
Source: Cornea - December 6, 2022 Category: Opthalmology Tags: Techniques Source Type: research

Ligneous Conjunctivitis Secondary to Viral Conjunctivitis
We present an interesting case of ligneous conjunctivitis caused by a viral infection that responded well to conservative management. Topical cyclosporine and heparin are a good treatment regimen that caused resolution of lesions and prevented recurrences. (Source: Cornea)
Source: Cornea - December 6, 2022 Category: Opthalmology Tags: Case Report Source Type: research

Infectious Crystalline Keratopathy Secondary to Mycobacterium chelonae
Conclusions: Although ICK is most commonly associated with Streptococcus species, it may be secondary to atypical bacteria including Mycobacterium species, underscoring the importance of diagnostic imaging and collecting corneal cultures to identify the pathogenic organism. (Source: Cornea)
Source: Cornea - December 6, 2022 Category: Opthalmology Tags: Case Report Source Type: research

Unintentional Descemet Cleft Introduces Novel Mechanism of Maintenance of Corneal Clarity
Conclusions: We hypothesize that corneal transparency can be maintained in the absence of endothelial cell function provided that aqueous humor cannot reach the cornea and disrupt the arrangement of the interfibrillar space. (Source: Cornea)
Source: Cornea - December 6, 2022 Category: Opthalmology Tags: Case Report Source Type: research

Antiamoebic Susceptibility in Acanthamoeba Keratitis: Comparison of Isolates From South India and Northern California
Conclusions: This study found no statistically significant differences in antiamoebic susceptibility of Indian versus US samples from Acanthamoeba keratitis clinical isolates. These findings suggest that differences in antiamoebic susceptibility are likely not responsible for differential outcomes in Acanthamoeba keratitis between the 2 locations. (Source: Cornea)
Source: Cornea - December 6, 2022 Category: Opthalmology Tags: Basic Investigation Source Type: research

“Groove and Peel” Deep Anterior Lamellar Keratoplasty: How Deep Can You Go?
Conclusions: The GP-DALK technique is effective in removing most of the corneal stroma and may be non-inferior to “big-bubble” deep anterior lamellar keratoplasty in some cases. (Source: Cornea)
Source: Cornea - December 6, 2022 Category: Opthalmology Tags: Basic Investigation Source Type: research

In Situ-forming Collagen Hydrogels Crosslinked by Multifunctional Polyethylene Glycol as a Matrix Therapy for Corneal Defects: 2-Month Follow-up In Vivo
Conclusions: The in situ-forming collagen-PEG gel promoted epithelialization that improved central corneal topography, epithelial layer morphology, and reduced expression of fibrotic and inflammatory biomarkers after 60 days compared to the saline group. (Source: Cornea)
Source: Cornea - December 6, 2022 Category: Opthalmology Tags: Basic Investigation Source Type: research

COVID-19 and Eye Banking: Ongoing Impacts of the Pandemic
Purpose: The purpose of this study was to assess the impact of ongoing waves of the COVID-19 pandemic and resulting guidelines on the corneal donor pool with resumption of clinical operations. Methods: A retrospective analysis of donors deemed eligible for corneal transplantation at an eye bank from July 1, 2020, through December 31, 2021. Donors ineligible due to meeting Eye Bank Association of America (EBAA) COVID-19 guidelines or a positive postmortem COVID-19 testing were examined. The correlation between COVID-19 rule outs and state COVID positivity was calculated. The number of scheduled surgeries, suitabl...
Source: Cornea - December 6, 2022 Category: Opthalmology Tags: Clinical Science Source Type: research

Deep Anterior Lamellar Keratoplasty: Can All Ruptures Be Fixed?
Conclusions: It is worth trying to repair all DM ruptures in DALK, and immediate penetrating keratoplasty conversion should be avoided. Understanding the physiomechanical mechanisms in DALK allows to correctly choose a proper rescue strategy to successfully repair DM ruptures. (Source: Cornea)
Source: Cornea - December 6, 2022 Category: Opthalmology Tags: Clinical Science Source Type: research

Validation and Repeatability of the Epidermolysis Bullosa Eye Disease Index in Dystrophic Epidermolysis Bullosa
Conclusions: Based on a 30-person repeated-measures study, we found that the EB-EDI has excellent reliability and validity specifically in patients with DEB. (Source: Cornea)
Source: Cornea - December 6, 2022 Category: Opthalmology Tags: Clinical Science Source Type: research

Microbial Keratitis in Patients With Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: Experience From a Tertiary Centre in Taiwan
Conclusions: Patients with SJS/TEN with SOCs are subject to recurrent corneal infections, which are responsible for deterioration of vision. Identifying the risk factors and aggressive treatment as early as possible is pivotal for infection control. (Source: Cornea)
Source: Cornea - December 6, 2022 Category: Opthalmology Tags: Clinical Science Source Type: research

Socioeconomic Correlates of Keratoconus Severity and Progression
Purpose: The purpose of this study was to investigate the social determinants of health for keratoconus. Methods: In this retrospective cohort study of patients with keratoconus, the electronic health record was reviewed for keratometry, treatments received, clinical comorbidities, and social characteristics. Outcomes included severe keratoconus at presentation (steep keratometry ≥52 diopters), disease progression (≥0.75 diopters increase from the first to the most recent clinical visit), and corneal transplantation. Logistic regression was used to evaluate factors associated with severity at presentation an...
Source: Cornea - December 6, 2022 Category: Opthalmology Tags: Clinical Science Source Type: research

Surgical Management of Intraocular Pressure With Ab Interno Canaloplasty in Postkeratoplasty Patients: 12-Month Results
This study was a single-center retrospective case series of postkeratoplasty eyes undergoing ABiC. Efficacy was evaluated based on graft survivability and mean reduction in IOP at 12 months postoperatively. Secondary end points consisted of visual acuity outcomes, number of topical hypotensive medications, and rate of complications. Results: ABiC was successfully performed in 17 eyes after keratoplasty (8 penetrating keratoplasty, 6 DSAEK, 2 penetrating keratoplasty + DSAEK, and 1 DMEK) with elevated IOP refractory to topical hypotensive medications. The baseline mean IOP was 26.2 ± 8.4 mm Hg and reduced significan...
Source: Cornea - December 6, 2022 Category: Opthalmology Tags: Clinical Science Source Type: research