Evolution and Antigenic Differentiation of Avian Influenza A(H7N9) Virus, China
Y. Liu et al. (Source: Emerging Infectious Diseases Journal)
Source: Emerging Infectious Diseases Journal - April 19, 2024 Category: Infectious Diseases Source Type: research

Viruses, Vol. 16, Pages 626: Detection and Characterization of Influenza A Virus Endemic Circulation in Suckling and Nursery Pigs Originating from Vaccinated Farms in the Same Production System
The objective of this study was to evaluate the detection of IAV in suckling and nursery piglets from IAV-vaccinated sows from farms with endemic IAV infections. Eight nasal swab collections were obtained from 135 two-week-old suckling piglets from four farms every other week from March to September 2013. Oral fluid samples were collected from the same group of nursery piglets. IAV RNA was detected in 1.64% and 31.01% of individual nasal swabs and oral fluids, respectively. H1N2 was detected most often, with sporadic detection of H1N1 and H3N2. Whole-genome sequences of IAV isolated from suckling piglets revealed an H1 hem...
Source: Viruses - April 18, 2024 Category: Virology Authors: Alessandra Silva Dias Amy L. Vincent Baker Rodney B. Baker Jianqiang Zhang Michael A. Zeller Pravina Kitikoon Phillip C. Gauger Tags: Article Source Type: research

Highly pathogenic avian influenza H5N1 virus infections of dairy cattle and livestock handlers in the United States of America
Volume 15, Issue 1, December 2024 . (Source: Virulence)
Source: Virulence - April 18, 2024 Category: Virology Authors: Hinh LyDepartment of Veterinary & Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, Twin Cities, MN, USA Source Type: research

Cost-effectiveness of high-dose influenza vaccination in the Netherlands: Incorporating the impact on both respiratory and cardiovascular hospitalizations
CONCLUSIONS: Implementing HD-QIV for adults aged 60 and over within the existing influenza vaccination campaign is highly cost effective. HD-QIV may support alleviating potential capacity issues in Dutch hospitals in the winter respiratory season.PMID:38631948 | DOI:10.1016/j.vaccine.2024.04.040 (Source: Vaccine)
Source: Vaccine - April 17, 2024 Category: Allergy & Immunology Authors: Simon van der Pol Florian Zeevat Maarten J Postma Cornelis Boersma Source Type: research

Comparing PCSK9 Monoclonal Antibody Treatment Strategies Following Myocardial Infarction Using Negative Control Outcomes: A Target Trial Emulation Study
CONCLUSION: A comparative effectiveness study of these treatments using the current approach would likely bias results due to the low number of PCSK9 mAb initiators.PMID:38629975 | DOI:10.1097/EDE.0000000000001730 (Source: Cancer Control)
Source: Cancer Control - April 17, 2024 Category: Cancer & Oncology Authors: Rosa Sloot Alexander Breskin Lisandro D Colantonio Andrew G Allmon Ying Yu Swati Sakhuja Ligong Chen Paul Muntner M Alan Brookhart Nafeesa Dhalwani Source Type: research

Influenza vaccination coverage and determinants of vaccination in peripheral arterial disease patients
Conclusions: This study highlights the low adherence to influenza vaccination in the PAD population of 2 university hospital centers. Vaccination is often related to age, and there is a need for adapted information regarding influenza consequences on cardiovascular disease overall, particularly on PAD. Addressing common information and advice about vaccination will be a challenge.PMID:38629325 | DOI:10.1024/0301-1526/a001120 (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - April 17, 2024 Category: Surgery Authors: Lucie Chastaingt Marie Laure Toba Carine Boulon Loubna Dari Joel Constans Hela Daoud Romain Chauvet Caroline Adou Julien Magne Philippe Lacroix Source Type: research

Cost-effectiveness of high-dose influenza vaccination in the Netherlands: Incorporating the impact on both respiratory and cardiovascular hospitalizations
CONCLUSIONS: Implementing HD-QIV for adults aged 60 and over within the existing influenza vaccination campaign is highly cost effective. HD-QIV may support alleviating potential capacity issues in Dutch hospitals in the winter respiratory season.PMID:38631948 | DOI:10.1016/j.vaccine.2024.04.040 (Source: Vaccine)
Source: Vaccine - April 17, 2024 Category: Allergy & Immunology Authors: Simon van der Pol Florian Zeevat Maarten J Postma Cornelis Boersma Source Type: research

Influenza vaccination coverage and determinants of vaccination in peripheral arterial disease patients
Conclusions: This study highlights the low adherence to influenza vaccination in the PAD population of 2 university hospital centers. Vaccination is often related to age, and there is a need for adapted information regarding influenza consequences on cardiovascular disease overall, particularly on PAD. Addressing common information and advice about vaccination will be a challenge.PMID:38629325 | DOI:10.1024/0301-1526/a001120 (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - April 17, 2024 Category: Surgery Authors: Lucie Chastaingt Marie Laure Toba Carine Boulon Loubna Dari Joel Constans Hela Daoud Romain Chauvet Caroline Adou Julien Magne Philippe Lacroix Source Type: research

GSE261920 Human long noncoding RNA, VILMIR, is induced by major respiratory viral infections and modulates the host interferon response
Contributors : Kristen John ; Ian Huntress ; Ethan Smith ; Hsuan Chou ; Tammy S Tollison ; Sergio Covarrubias ; Elisa Crisci ; Susan Carpenter ; Xinxia PengSeries Type : Non-coding RNA profiling by high throughput sequencingOrganism : Homo sapiensLong noncoding RNAs (lncRNAs) are a newer class of noncoding transcripts identified as key regulators of biological processes. Here we aimed to identify novel lncRNA targets that play critical roles in major human respiratory viral infections by systematically mining large-scale transcriptomic datasets. Using bulk RNA-sequencing (RNA-seq) analysis, we identified a previous...
Source: GEO: Gene Expression Omnibus - April 17, 2024 Category: Genetics & Stem Cells Tags: Non-coding RNA profiling by high throughput sequencing Homo sapiens Source Type: research

Potential impact of annual vaccination with reformulated COVID-19 vaccines: Lessons from the US COVID-19 scenario modeling hub
ConclusionsCOVID-19 is projected to be a significant public health threat over the coming 2 years. Broad vaccination has the potential to substantially reduce the burden of this disease, saving tens of thousands of lives each year. (Source: PLoS Medicine)
Source: PLoS Medicine - April 17, 2024 Category: Internal Medicine Authors: Sung-mok Jung Source Type: research

Synthesis of Rupestonic Acid L-Ephedrine Derivatives with Preliminary In vitro Anti-influenza Viral Activity
CONCLUSION: The rupestonic acid L-ephedrine ester (A) and rupestonic acid L-ephedrine complex (B) were synthesized and characterized using 1H NMR and 13C NMR. Moreover, their purity was determined by HPLC. Both compounds A and B exhibited more potent activities against the strains of A/PR/8/34 (H1N1) and A/FM/1/47 (H1N1) than rupestonic acid. Compound A can be regarded as a very promising lead compound for the development of anti-influenza inhibitors. Based on these results, more rupestonic acid derivatives will be designed and synthesized in the future for the development of anti-influenza inhibitors.PMID:38623973 | DOI:1...
Source: Current Pharmaceutical Design - April 16, 2024 Category: Drugs & Pharmacology Authors: Jianping Yong Canzhong Lu Source Type: research

Comparative Analysis of Clinical Outcomes Using Propensity Score Matching: Coronavirus Disease 2019 vs. Seasonal Influenza in Korea
CONCLUSION: The omicron group did not demonstrate better clinical outcomes than the pre-omicron group, and exhibited significant disease severity compared to the influenza group. Considering the likely persistence of COVID-19 infections, it is imperative to sustain comprehensive studies and ongoing policy support for the virus to enhance the prognosis for individuals affected by COVID-19.PMID:38622937 | DOI:10.3346/jkms.2024.39.e128 (Source: J Korean Med Sci)
Source: J Korean Med Sci - April 16, 2024 Category: General Medicine Authors: Jae Kyeom Sim Hye Sun Lee Juyeon Yang Jin Gwack Bryan Inho Kim Jeong-Ok Cha Kyung Hoon Min Young Seok Lee Severe Acute Respiratory Infection (SARI) Investigators Source Type: research