Antibody-independent surface plasmon resonance assays for influenza vaccine quality control
Appl Microbiol Biotechnol. 2024 Apr 24;108(1):307. doi: 10.1007/s00253-024-13145-y.ABSTRACTSurface plasmon resonance (SPR)-based biosensors have emerged as a powerful platform for bioprocess monitoring due to their ability to detect biointeractions in real time, without the need for labeling. Paramount for the development of a robust detection platform is the immobilization of a ligand with high specificity and affinity for the in-solution species of interest. Following the 2009 H1N1 pandemic, much effort has been made toward the development of quality control platforms for influenza A vaccine productions, many of which ha...
Source: Applied Microbiology and Biotechnology - April 24, 2024 Category: Microbiology Authors: Benjamin Serafin Amine Kamen Gregory de Crescenzo Olivier Henry Source Type: research
Discovery of baloxavir sodium as a novel anti-CCHFV inhibitor: biological evaluation of in vitro and in vivo
This study identified baloxavir sodium as a novel scaffold structure and mechanism of anti-CCHF compound, providing a promising new strategy for clinical treatment of CCHF after further optimization.PMID:38657838 | DOI:10.1016/j.antiviral.2024.105890 (Source: Antiviral Research)
Source: Antiviral Research - April 24, 2024 Category: Virology Authors: Kai Liu Liushuai Li Yajie Liu Xi Wang Jia Liu Jiang Li Fei Deng Runze Zhang Yiwu Zhou Zhihong Hu Wu Zhong Manli Wang Chun Guo Source Type: research
Non-specific effects of the inactivated influenza vaccine. A test-negative study: The inactivated influenza vaccine and SARS-CoV-2 infections
CONCLUSIONS: While earlier observational studies suggested a protective non-specific effect of IIV and SARS-CoV-2 infections, this smaller, but well controlled test-negative design study does not suggest an effect, either positive or negative. Larger test-negative design studies, or alternative designs such as the self-controlled case series design are needed to confirm these findings and provide more definite answers on the topic.PMID:38658205 | DOI:10.1016/j.vaccine.2024.04.044 (Source: Vaccine)
Source: Vaccine - April 24, 2024 Category: Allergy & Immunology Authors: Anne Jasmijn Sellies Mirjam J Knol Hester E de Melker Patricia C J L Bruijning-Verhagen Annemarijn R de Boer Source Type: research
Epidemiological characteristics of human infections with avian influenza A(H5N6) virus, China and Laos: A multiple case descriptive analysis, February 2014-June 2023
CONCLUSION: As A(H5N6) continues to circulate and cause severe illness, surveillance and prompt information sharing is important for creating and implementing effective public health measures to reduce the likelihood of additional human infections.PMID:38655247 | PMC:PMC11037882 | DOI:10.14745/ccdr.v50i12a09 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - April 24, 2024 Category: Infectious Diseases Authors: Simran Sandhu Christina Ferrante Aaron MacCosham Nicole Atchessi Christina Bancej Source Type: research
Disease burden attributable to respiratory syncytial virus outbreaks in long-term care
CONCLUSION: Integration of RSV into existing respiratory pathogen surveillance programs is important to characterize susceptibility, transmissibility and virulence of RSV in at-risk populations. There is a need for public health organizations to publish the findings from outbreak investigations to provide evidence to inform RSV outbreak prevention and response in LTCH settings.PMID:38655245 | PMC:PMC11037883 | DOI:10.14745/ccdr.v50i12a03 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - April 24, 2024 Category: Infectious Diseases Authors: Christina Ferrante Christina Bancej Nicole Atchessi Source Type: research
Canadian vaccine safety surveillance reports following immunization with seasonal influenza vaccines, 2021-2022
CONCLUSION: Findings from our analysis of reports to CAEFISS and CVD following vaccination with SIV are consistent with the known safety profile of SIVs distributed during the 2021/2022 influenza season. The majority of reports were non-serious with the most common AEFI symptoms occurring at the vaccination site or systemic symptoms that were self-limiting. The majority of vaccination error reports involved the administration of the vaccine at an inappropriate site, although no serious AEFIs were reported.PMID:38655243 | PMC:PMC11037881 | DOI:10.14745/ccdr.v50i12a02 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - April 24, 2024 Category: Infectious Diseases Authors: Elissa Giang Yuhui Xu Thivya Naganathan Natalia Abraham Marie-Th érèse Bawolak Battouli Said Salim Ashley Weeks Amanda Shaw Susanna Ogunnaike-Cooke Source Type: research
Epidemiological characteristics of human infections with avian influenza A(H5N6) virus, China and Laos: A multiple case descriptive analysis, February 2014-June 2023
CONCLUSION: As A(H5N6) continues to circulate and cause severe illness, surveillance and prompt information sharing is important for creating and implementing effective public health measures to reduce the likelihood of additional human infections.PMID:38655247 | PMC:PMC11037882 | DOI:10.14745/ccdr.v50i12a09 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - April 24, 2024 Category: Infectious Diseases Authors: Simran Sandhu Christina Ferrante Aaron MacCosham Nicole Atchessi Christina Bancej Source Type: research
Disease burden attributable to respiratory syncytial virus outbreaks in long-term care
CONCLUSION: Integration of RSV into existing respiratory pathogen surveillance programs is important to characterize susceptibility, transmissibility and virulence of RSV in at-risk populations. There is a need for public health organizations to publish the findings from outbreak investigations to provide evidence to inform RSV outbreak prevention and response in LTCH settings.PMID:38655245 | PMC:PMC11037883 | DOI:10.14745/ccdr.v50i12a03 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - April 24, 2024 Category: Infectious Diseases Authors: Christina Ferrante Christina Bancej Nicole Atchessi Source Type: research
Canadian vaccine safety surveillance reports following immunization with seasonal influenza vaccines, 2021-2022
CONCLUSION: Findings from our analysis of reports to CAEFISS and CVD following vaccination with SIV are consistent with the known safety profile of SIVs distributed during the 2021/2022 influenza season. The majority of reports were non-serious with the most common AEFI symptoms occurring at the vaccination site or systemic symptoms that were self-limiting. The majority of vaccination error reports involved the administration of the vaccine at an inappropriate site, although no serious AEFIs were reported.PMID:38655243 | PMC:PMC11037881 | DOI:10.14745/ccdr.v50i12a02 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - April 24, 2024 Category: Infectious Diseases Authors: Elissa Giang Yuhui Xu Thivya Naganathan Natalia Abraham Marie-Th érèse Bawolak Battouli Said Salim Ashley Weeks Amanda Shaw Susanna Ogunnaike-Cooke Source Type: research
Epidemiological characteristics of human infections with avian influenza A(H5N6) virus, China and Laos: A multiple case descriptive analysis, February 2014-June 2023
CONCLUSION: As A(H5N6) continues to circulate and cause severe illness, surveillance and prompt information sharing is important for creating and implementing effective public health measures to reduce the likelihood of additional human infections.PMID:38655247 | PMC:PMC11037882 | DOI:10.14745/ccdr.v50i12a09 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - April 24, 2024 Category: Infectious Diseases Authors: Simran Sandhu Christina Ferrante Aaron MacCosham Nicole Atchessi Christina Bancej Source Type: research
Disease burden attributable to respiratory syncytial virus outbreaks in long-term care
CONCLUSION: Integration of RSV into existing respiratory pathogen surveillance programs is important to characterize susceptibility, transmissibility and virulence of RSV in at-risk populations. There is a need for public health organizations to publish the findings from outbreak investigations to provide evidence to inform RSV outbreak prevention and response in LTCH settings.PMID:38655245 | PMC:PMC11037883 | DOI:10.14745/ccdr.v50i12a03 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - April 24, 2024 Category: Infectious Diseases Authors: Christina Ferrante Christina Bancej Nicole Atchessi Source Type: research
Canadian vaccine safety surveillance reports following immunization with seasonal influenza vaccines, 2021-2022
CONCLUSION: Findings from our analysis of reports to CAEFISS and CVD following vaccination with SIV are consistent with the known safety profile of SIVs distributed during the 2021/2022 influenza season. The majority of reports were non-serious with the most common AEFI symptoms occurring at the vaccination site or systemic symptoms that were self-limiting. The majority of vaccination error reports involved the administration of the vaccine at an inappropriate site, although no serious AEFIs were reported.PMID:38655243 | PMC:PMC11037881 | DOI:10.14745/ccdr.v50i12a02 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - April 24, 2024 Category: Infectious Diseases Authors: Elissa Giang Yuhui Xu Thivya Naganathan Natalia Abraham Marie-Th érèse Bawolak Battouli Said Salim Ashley Weeks Amanda Shaw Susanna Ogunnaike-Cooke Source Type: research
Epidemiological characteristics of human infections with avian influenza A(H5N6) virus, China and Laos: A multiple case descriptive analysis, February 2014-June 2023
CONCLUSION: As A(H5N6) continues to circulate and cause severe illness, surveillance and prompt information sharing is important for creating and implementing effective public health measures to reduce the likelihood of additional human infections.PMID:38655247 | PMC:PMC11037882 | DOI:10.14745/ccdr.v50i12a09 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - April 24, 2024 Category: Infectious Diseases Authors: Simran Sandhu Christina Ferrante Aaron MacCosham Nicole Atchessi Christina Bancej Source Type: research
Disease burden attributable to respiratory syncytial virus outbreaks in long-term care
CONCLUSION: Integration of RSV into existing respiratory pathogen surveillance programs is important to characterize susceptibility, transmissibility and virulence of RSV in at-risk populations. There is a need for public health organizations to publish the findings from outbreak investigations to provide evidence to inform RSV outbreak prevention and response in LTCH settings.PMID:38655245 | PMC:PMC11037883 | DOI:10.14745/ccdr.v50i12a03 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - April 24, 2024 Category: Infectious Diseases Authors: Christina Ferrante Christina Bancej Nicole Atchessi Source Type: research
Canadian vaccine safety surveillance reports following immunization with seasonal influenza vaccines, 2021-2022
CONCLUSION: Findings from our analysis of reports to CAEFISS and CVD following vaccination with SIV are consistent with the known safety profile of SIVs distributed during the 2021/2022 influenza season. The majority of reports were non-serious with the most common AEFI symptoms occurring at the vaccination site or systemic symptoms that were self-limiting. The majority of vaccination error reports involved the administration of the vaccine at an inappropriate site, although no serious AEFIs were reported.PMID:38655243 | PMC:PMC11037881 | DOI:10.14745/ccdr.v50i12a02 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - April 24, 2024 Category: Infectious Diseases Authors: Elissa Giang Yuhui Xu Thivya Naganathan Natalia Abraham Marie-Th érèse Bawolak Battouli Said Salim Ashley Weeks Amanda Shaw Susanna Ogunnaike-Cooke Source Type: research
