Pharmacy-Based Influenza Vaccination: A Study of Patient Acceptance in Romania
(Source: Risk Management and Healthcare Policy)
Source: Risk Management and Healthcare Policy - April 23, 2024 Category: Health Management Tags: Risk Management and Healthcare Policy Source Type: research
Interim Estimates of 2023-2024 Seasonal Influenza Vaccine Effectiveness Among Adults in Korea
In this study, we aimed to estimate the interim vaccine effectiveness (VE) of the influenza vaccination to prevent influenza during the early season. From November 1, 2023, to December 31, 2023, we enrolled 2,632 subjects with influenza-like illness from eight hospitals participating in hospital-based influenza morbidity and mortality surveillance. A retrospective test-negative case-control study was conducted to estimate the VE. The results showed an adjusted VE of 22.5% (95% confidence interval [CI], 6.6 to 35.8) for the total population. The adjusted VE was 22.3% (95% CI, 6.1 to 35.7) for influenza A and 9.4% (95% CI, -...
Source: Journal of Korean Medical Science - April 23, 2024 Category: Biomedical Science Authors: Yu Jung Choi Jang Wook Sohn Won Suk Choi Seong-Heon Wie Jacob Lee Jin-Soo Lee Hye Won Jeong Joong Sik Eom Eliel Nham Hye Seong Jin Gu Yoon Ji Yun Noh Joon Young Song Hee Jin Cheong Woo Joo Kim Source Type: research
The influenza landscape and vaccination coverage in older adults during the SARS-Cov-2 pandemic: data from Several European Countries and Israel
Expert Rev Respir Med. 2024 Apr 23. doi: 10.1080/17476348.2024.2340470. Online ahead of print.ABSTRACTINTRODUCTION: The Raise Awareness of Influenza Strategies in Europe (RAISE) group gathered information about the healthcare burden of influenza (hospitalizations, intensive care unit [ICU] admissions, and excess deaths), surveillance systems, and the vaccine coverage rate (VCR) in older adults in 18 European countries and Israel.AREAS COVERED: Published medical literature and official medical documentation on the influenza disease burden in the participating countries were reviewed from 2010/11 until the 2022/23 influenza ...
Source: Expert Review of Respiratory Medicine - April 23, 2024 Category: Respiratory Medicine Authors: George Kassianos Jean-Marie Cohen Rok Civljak Nadav Davidovitch Oana Falup Pecurariu Filipe Froes Andrei Galev Inga Ivaskeviciene Kadri K õivumägi Zuzana Kristufkova Ernest Kuchar Jan Kyncl Helena C Maltezou Milo š Marković Aneta Nitsch-Osuch Raul Ort Source Type: research
Safety and effectiveness of isavuconazole in real-life non-neutropenic patients
There is a notable change in the profile of patients with invasive fungal infections (IFI): there has been a progressive rise of such infections in non-neutropenic population (i.e., COVID-19, influenza, biologic agents, corticosteroids, cancer, chronic obstructive pulmonary disorder [COPD] or cirrhosis) [1 –3]. However, information concerning the management of non-neutropenic patients with IFI remains limited. Caution should be exercised before these patients are treated like those who are neutropenic, given a considerable variability in pathogenesis and clinical manifestations of IFI [4]. (Source: International Journal ...
Source: International Journal of Infectious Diseases - April 23, 2024 Category: Infectious Diseases Authors: Patricia Monz ó-Gallo, Carlos Lopera, Ana M Badía-Tejero, Marina Machado, Julio García-Rodríguez, Pablo Vidal-Cortés, Esperanza Merino, Jorge Calderón, Jesús Fortún, Zaira R. Palacios-Baena, Javier Pemán, Joan Roig Sanchis, Manuela Aguilar-Guisad Source Type: research
Errors in Results and Discussion
This article was corrected online. (Source: JAMA Internal Medicine)
Source: JAMA Internal Medicine - April 22, 2024 Category: Internal Medicine Source Type: research
Locations and structures of influenza A virus packaging-associated signals and other functional elements via an < i > in silico < /i > pipeline for predicting constrained features in RNA viruses
by Emma Beniston, Jordan P. Skittrall
Influenza A virus contains regions of its segmented genome associated with ability to package the segments into virions, but many such regions are poorly characterised. We provide detailed predictions of the key locations within these packaging-associated regions, and their structures, by applying a recently-improved pipeline for delineating constrained regions in RNA viruses and applying structural prediction algorithms. We find and characterise other known constrained regions within influenza A genomes, including the region associated with the PA-X frameshift, regions associated wit...
Source: PLoS Computational Biology - April 22, 2024 Category: Biology Authors: Emma Beniston Source Type: research
Estimating the incidence of COVID-19, influenza and respiratory syncytial virus infection in three regions of Queensland, Australia, winter 2022: findings from a novel longitudinal testing-based sentinel surveillance programme
Conclusion
This testing-based surveillance programme could estimate disease trends and be a useful tool in settings where testing is less common or accessible. Difficulties with recruitment meant the study was underpowered. The frontline sentinel nature of workplaces meant participants were not representative of the general population but were high-risk groups providing early warning of disease. (Source: BMJ Open)
Source: BMJ Open - April 22, 2024 Category: General Medicine Authors: May, F., Ginige, S., Firman, E., Li, Y. S., Soonarane, Y. K., Smoll, N., Hunter, I., Pery, B., Macfarlane, B., Bladen, T., Allen, T., Green, T., Walker, J., Slinko, V., Stickley, M., Khandaker, G., Anuradha, S., Wattiaux, A. Tags: Open access, Public health, COVID-19 Source Type: research
Extracorporeal membrane oxygenation technology for adults: an evidence mapping based on systematic reviews
ConclusionsThere is limited available evidence for ECMO that large sample, multi-center, and multinational RCTs are needed. Most clinical topics are reported as beneficial or probably beneficial of SRs for ECMO. Evidence mapping is a valuable and reliable methodology to identify and present the existing evidence about therapeutic interventions. (Source: European Journal of Medical Research)
Source: European Journal of Medical Research - April 22, 2024 Category: Research Source Type: research
Isolation and genetic characterization of multiple genotypes of both H5 and H7 avian influenza viruses from environmental water in the Izumi plain, Kagoshima prefecture, Japan during the 2021/22 winter season
This study underscores the importance of monitoring both HPAIVs and LPAIVs to understand avian influenza virus ecology in migratory waterfowl populations.PMID:38640701 | DOI:10.1016/j.cimid.2024.102182 (Source: Comparative immunology, microbiology and infectious diseases.)
Source: Comparative immunology, microbiology and infectious diseases. - April 19, 2024 Category: Allergy & Immunology Authors: Kosuke Okuya Mana Esaki Kaori Tokorozaki Taichi Hasegawa Makoto Ozawa Source Type: research
Immunogenicity and protective efficacy of a multivalent herpesvirus vectored vaccine against H9N2 low pathogenic avian influenza in chicken
This study investigated H9- and ND-specific humoral and mucosal responses, H9-specific cell-mediated immunity, and protection conferred by the rHVT-H9-F vaccine in specific pathogen-free (SPF) chickens. Vaccination elicited systemic NDV F- and AIV H9-specific antibody response but also local antibodies in eye wash fluid and oropharyngeal swabs. The ex vivo H9-specific stimulation of splenic and pulmonary T cells in the vaccinated group demonstrated the ability of vaccination to induce systemic and local cellular responses. The clinical protection against a challenge using a LPAIV H9N2 strain of the G1 lineage isolated in M...
Source: Vaccine - April 19, 2024 Category: Allergy & Immunology Authors: Fiona Ingrao Eva Ngabirano Fabienne Rauw Gwena ëlle Dauphin B énédicte Lambrecht Source Type: research
Safety of concomitant administration of 23-valent polysaccharide pneumococcal vaccine and influenza vaccine among the elderly
CONCLUSIONS: Concomitant administration of PPSV-23 and influenza vaccine in the elderly was not associated with a higher risk of most prespecified adverse events (AEs) compared to sequential vaccination. This study supports the safety of concomitant administration of PPSV-23 and influenza vaccine.PMID:38641496 | DOI:10.1016/j.vaccine.2024.03.078 (Source: Vaccine)
Source: Vaccine - April 19, 2024 Category: Allergy & Immunology Authors: Heehyun Won Jeong Ah Kim Na-Young Jeong Nam-Kyong Choi Source Type: research
The global impact of SARS-CoV-2 variant BA.2.86: a comprehensive analysis with the latest developments and transmission trends - an epidemiological study
CONCLUSIONS: The SARS-CoV-2, novel variant BA.2.86, spread over six continents and 89 countries and affected 19,532 people worldwide. The disease is more prevalent in the United Kingdom, United States of America, and European countries. The detection of the disease in multiple continents and countries suggests some degree of transmissibility. Global health authorities need to rethink their policies and implement strict strategies to eradicate emerging variants and minimize the global disease burden.PMID:38639533 | DOI:10.26355/eurrev_202404_35928 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - April 19, 2024 Category: Drugs & Pharmacology Authors: S A Meo A S Meo D M Halepoto Source Type: research
Evolution and Antigenic Differentiation of Avian Influenza A(H7N9) Virus, China
Emerg Infect Dis. 2024 Apr 19;30(6). doi: 10.3201/eid3006.230530. Online ahead of print.ABSTRACTWe characterized the evolution and molecular characteristics of avian influenza A(H7N9) viruses isolated in China during 2021-2023. We systematically analyzed the 10-year evolution of the hemagglutinin gene to determine the evolutionary branch. Our results showed recent antigenic drift, providing crucial clues for updating the H7N9 vaccine and disease prevention and control.PMID:38640498 | DOI:10.3201/eid3006.230530 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - April 19, 2024 Category: Infectious Diseases Authors: Yang Liu Yuhua Chen Zhiyi Yang Yaozhong Lin Siyuan Fu Junhong Chen Lingyu Xu Tengfei Liu Beibei Niu Qiuhong Huang Haixia Liu Chaofeng Zheng Ming Liao Weixin Jia Source Type: research
Evolution and Antigenic Differentiation of Avian Influenza A(H7N9) Virus, China
Y. Liu et al. (Source: Emerging Infectious Diseases Journal)
Source: Emerging Infectious Diseases Journal - April 19, 2024 Category: Infectious Diseases Source Type: research
Viruses, Vol. 16, Pages 626: Detection and Characterization of Influenza A Virus Endemic Circulation in Suckling and Nursery Pigs Originating from Vaccinated Farms in the Same Production System
The objective of this study was to evaluate the detection of IAV in suckling and nursery piglets from IAV-vaccinated sows from farms with endemic IAV infections. Eight nasal swab collections were obtained from 135 two-week-old suckling piglets from four farms every other week from March to September 2013. Oral fluid samples were collected from the same group of nursery piglets. IAV RNA was detected in 1.64% and 31.01% of individual nasal swabs and oral fluids, respectively. H1N2 was detected most often, with sporadic detection of H1N1 and H3N2. Whole-genome sequences of IAV isolated from suckling piglets revealed an H1 hem...
Source: Viruses - April 18, 2024 Category: Virology Authors: Alessandra Silva Dias Amy L. Vincent Baker Rodney B. Baker Jianqiang Zhang Michael A. Zeller Pravina Kitikoon Phillip C. Gauger Tags: Article Source Type: research
