Influenza vaccine uptake in juvenile idiopathic arthritis: a multi-centre cross-sectional study
Conclusion: Despite variations among countries, the uptake of influenza vaccines remains low in children with JIA. Improving awareness among families about the importance of influenza vaccination may increase vaccination rates in children with rheumatic diseases.What is Known:• Rheumatic children are at increased risk for influenza infection due to immunosuppressive therapy and immune dysregulation.• Influenza vaccine is formally recommended to children with rheumatic diseases.What is New:• This multicentre study showed that influenza vaccine uptake rates remain suboptimal among children with Juvenile Idiopathic Ar...
Source: European Journal of Pediatrics - April 15, 2024 Category: Pediatrics Source Type: research
Exploring the immune-inflammatory mechanism of Maxing Shigan Decoction in treating influenza virus A-induced pneumonia based on an integrated strategy of single-cell transcriptomics and systems biology
ConclusionMXSGD may play an anti-inflammatory and immunoregulatory role by regulating intestinal microbiome and intestinal metabolic small molecules, and ultimately play a role in the treatment of influenza A virus pneumonia. (Source: European Journal of Medical Research)
Source: European Journal of Medical Research - April 15, 2024 Category: Research Source Type: research
SARS-CoV-2 and influenza virus coinfections in the Tuscan population during the 2021/2022 influenza season
The 2021/2022 influenza season was not characterised by a well-defined incidence peak. As reported by the Italian National Institute of Health, a high value of incidence of influenza cases was recorded in week 13, but it was still lower than in other influenza seasons. This abnormal circulation was probably due to relaxation of the COVID-19 pandemic restriction measures, which greatly reduced the circulation of respiratory-transmitted viruses, including human respiratory syncytial virus (HRSV). The symptoms of SARS-CoV-2 and influenza are quite similar, sharing the human-to-human transmission route via respiratory droplets...
Source: Journal of Preventive Medicine and Hygiene - April 15, 2024 Category: International Medicine & Public Health Authors: Ilaria Manini, Giovanna Milano, Serena Marchi, Ilaria Vicenti, Camilla Biba, Lia Fiaschi, Claudia Maria Trombetta, Giacomo Lazzeri, Emanuele Montomoli Source Type: research
Avian ‘Bird’ Flu – undue media panic or genuine concern for pandemic potential requiring global preparedness action?
epidemics, avian influenza, H5N1, highly pathogenic avian influenza, HPAI (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - April 15, 2024 Category: Infectious Diseases Authors: Eskild Petersen, Ziad A Memish, David S Hui, Alessandra Scagliarini, Lone Simonsen, Edgar Simulundu, Jennifer Bloodgood, Lucille Blumberg, Shui- Shan Lee, Alimuddin Zumla Tags: Editorial Source Type: research
Seasonal influenza vaccine performance and the potential benefits of mRNA vaccines
Volume 20, Issue 1, December 2024 . (Source: Human Vaccines and Immunotherapeutics)
Source: Human Vaccines and Immunotherapeutics - April 15, 2024 Category: Allergy & Immunology Authors: Colin A. RussellRon A. M. FouchierParinaz GhaswallaYoonyoung ParkNevena VicicJintanat AnanworanichRaffael NachbagauerDeborah Rudina Department of Medical Microbiology & Infection Prevention, Amsterdam University Medical Center, University of Amsterdam, A Source Type: research
Design, synthesis, docking, and antiviral evaluation of some novel pyrimidinone-based α-aminophosphonates as potent H1N1 and HCoV-229E inhibitors
Bioorg Chem. 2024 Apr 8;147:107353. doi: 10.1016/j.bioorg.2024.107353. Online ahead of print.ABSTRACTDialkyl/aryl aminophosphonates, 3a-g and 4a-e were synthesized using the LiClO4 catalyzed Kabachnic Fields-type reaction straightforwardly and efficiently. The synthesized phosphonates structures were characterized using elemental analyses, FT-IR, 1H NMR, 13C NMR, and MS spectroscopy. The new compounds were subjected to in-silico molecular docking simulations to evaluate their potential inhibition against Influenza A Neuraminidase and RNA-dependent RNA polymerase of human coronavirus 229E. Subsequently, the compounds were f...
Source: Bioorganic Chemistry - April 14, 2024 Category: Chemistry Authors: Hend A Hekal Omar M Hammad Nasser R El-Brollosy Maha M Salem Abdou K Allayeh Source Type: research
Is HealthPathways viewed as a useful and trustworthy source of information by health professionals?
ConclusionsHealthPathways is viewed as a useful and trusted source of information for health professionals in the North Coast NSW region. HealthPathways provides an opportunity for timely dissemination of information during critical events, including natural disasters and emergencies.PMID:38616105 | DOI:10.1071/AH23107 (Source: Australian Health Review)
Source: Australian Health Review - April 14, 2024 Category: Hospital Management Authors: Rebecca Tretheway Victoria Visser Sarah Mollard Source Type: research
Is HealthPathways viewed as a useful and trustworthy source of information by health professionals?
ConclusionsHealthPathways is viewed as a useful and trusted source of information for health professionals in the North Coast NSW region. HealthPathways provides an opportunity for timely dissemination of information during critical events, including natural disasters and emergencies.PMID:38616105 | DOI:10.1071/AH23107 (Source: Australian Health Review)
Source: Australian Health Review - April 14, 2024 Category: Hospital Management Authors: Rebecca Tretheway Victoria Visser Sarah Mollard Source Type: research
Is HealthPathways viewed as a useful and trustworthy source of information by health professionals?
ConclusionsHealthPathways is viewed as a useful and trusted source of information for health professionals in the North Coast NSW region. HealthPathways provides an opportunity for timely dissemination of information during critical events, including natural disasters and emergencies.PMID:38616105 | DOI:10.1071/AH23107 (Source: Australian Health Review)
Source: Australian Health Review - April 14, 2024 Category: Hospital Management Authors: Rebecca Tretheway Victoria Visser Sarah Mollard Source Type: research
