Interaction and Antiviral Treatment of Coinfection between SARS-CoV-2 and Influenza in Vitro
CONCLUSIONS: In coinfection, the replication of SARS-CoV-2 would be interfered by influenza H1N1. Compared with molnupiravir or baloxavir monotherapy, treatment with a combination of molnupiravir and baloxavir should be considered for early treatment in patients with SARS-CoV-2 and influenza coinfection.PMID:38621598 | DOI:10.1016/j.virusres.2024.199371 (Source: Virus Research)
Source: Virus Research - April 15, 2024 Category: Virology Authors: Danlei Liu Ka-Yi Leung Hoi-Yan Lam Ruiqi Zhang Yujing Fan Xiaochun Xie Kwok-Hung Chan Ivan Fan-Ngai Hung Source Type: research
Respiratory pathogenic microbial infections: a narrative review
This article aims to review community-acquired respiratory illnesses covering a broad spectrum of viruses, bacteria, and atypical microorganisms and focuses on the cluster prevalence of multiple known respiratory pathogens in China, thereby providing effective prevention and control measures.PMID:38617014 | PMC:PMC11008481 | DOI:10.7150/ijms.93628 (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - April 15, 2024 Category: Biomedical Science Authors: Yiyin Long Yan Zheng Changlin Li Zhanjun Guo Peng Li Fuqing Zhang Wei Liu Yuliang Wang Source Type: research
Exploring the immune-inflammatory mechanism of Maxing Shigan Decoction in treating influenza virus A-induced pneumonia based on an integrated strategy of single-cell transcriptomics and systems biology
CONCLUSION: MXSGD may play an anti-inflammatory and immunoregulatory role by regulating intestinal microbiome and intestinal metabolic small molecules, and ultimately play a role in the treatment of influenza A virus pneumonia.PMID:38622728 | DOI:10.1186/s40001-024-01777-9 (Source: Cell Research)
Source: Cell Research - April 15, 2024 Category: Cytology Authors: Shiying Zhang Bei Li Liuting Zeng Kailin Yang Junyao Jiang Fangguo Lu Ling Li Weiqing Li Source Type: research
Interaction and Antiviral Treatment of Coinfection between SARS-CoV-2 and Influenza in Vitro
CONCLUSIONS: In coinfection, the replication of SARS-CoV-2 would be interfered by influenza H1N1. Compared with molnupiravir or baloxavir monotherapy, treatment with a combination of molnupiravir and baloxavir should be considered for early treatment in patients with SARS-CoV-2 and influenza coinfection.PMID:38621598 | DOI:10.1016/j.virusres.2024.199371 (Source: Cell Research)
Source: Cell Research - April 15, 2024 Category: Cytology Authors: Danlei Liu Ka-Yi Leung Hoi-Yan Lam Ruiqi Zhang Yujing Fan Xiaochun Xie Kwok-Hung Chan Ivan Fan-Ngai Hung Source Type: research
Cutting Edge: First Lung Infection Permanently Enlarges Lymph Nodes and Enhances New T Cell Responses
J Immunol. 2024 Apr 15:ji2400010. doi: 10.4049/jimmunol.2400010. Online ahead of print.ABSTRACTHumans experience frequent respiratory infections. Immunology and vaccinology studies in mice are typically performed in naive specific pathogen-free animals responding to their very first respiratory challenge. We found that the first respiratory infection induces lifelong enlargement of the lung-draining mediastinal lymph nodes (medLNs). Furthermore, infection-experienced medLNs supported better naive T cell surveillance and effector responses to new unrelated infections that exhibited more biased accumulation and memory establ...
Source: Journal of Immunology - April 15, 2024 Category: Allergy & Immunology Authors: J Michael Stolley Milcah C Scott Stephen D O'Flanagan Marco K ünzli Courtney A Matson Eyob Weyu Ryan A Langlois Vaiva Vezys David Masopust Source Type: research
In Patients With Inflammatory Bowel Disease, Racial Disparities Exist in Burden of Vaccine-preventable Disease Hospitalizations and Outcomes
CONCLUSIONS: Significant racial disparities in VPD hospitalization and in-hospital morbidity were found among adults with IBD in the United States. With the increasing prevalence of IBD in non-white populations, targeted efforts are needed to improve health equity.PMID:38619208 | DOI:10.1097/MCG.0000000000002005 (Source: Herpes)
Source: Herpes - April 15, 2024 Category: Infectious Diseases Authors: Christian Karime Miguel Salazar Cecily N Black Freddy Caldera Philip N Okafor Muhammad B Hammami Jana G Hashash Francis A Farraye Source Type: research
Automatic ultrasensitive lateral flow immunoassay based on a color-enhanced signal amplification strategy
Biosens Bioelectron. 2024 Mar 30;256:116262. doi: 10.1016/j.bios.2024.116262. Online ahead of print.ABSTRACTLateral flow immunoassays (LFIAs) are an essential and widely used point-of-care test for medical diagnoses. However, commercial LFIAs still have low sensitivity and specificity. Therefore, we developed an automatic ultrasensitive dual-color enhanced LFIA (DCE-LFIA) by applying an enzyme-induced tyramide signal amplification method to a double-antibody sandwich LFIA for antigen detection. The DCE-LFIA first specifically captured horseradish peroxidase (HRP)-labeled colored microspheres at the Test line, and then depo...
Source: Biosensors and Bioelectronics - April 15, 2024 Category: Biotechnology Authors: Huiyang Jie Yu Wang Meng Zhao Xiuzhen Wang Zhong Wang Lingliao Zeng Xiaobao Cao Tao Xu Fan Xia Qian Liu Source Type: research
Interaction and Antiviral Treatment of Coinfection between SARS-CoV-2 and Influenza in Vitro
CONCLUSIONS: In coinfection, the replication of SARS-CoV-2 would be interfered by influenza H1N1. Compared with molnupiravir or baloxavir monotherapy, treatment with a combination of molnupiravir and baloxavir should be considered for early treatment in patients with SARS-CoV-2 and influenza coinfection.PMID:38621598 | DOI:10.1016/j.virusres.2024.199371 (Source: Virus Research)
Source: Virus Research - April 15, 2024 Category: Virology Authors: Danlei Liu Ka-Yi Leung Hoi-Yan Lam Ruiqi Zhang Yujing Fan Xiaochun Xie Kwok-Hung Chan Ivan Fan-Ngai Hung Source Type: research
Respiratory pathogenic microbial infections: a narrative review
This article aims to review community-acquired respiratory illnesses covering a broad spectrum of viruses, bacteria, and atypical microorganisms and focuses on the cluster prevalence of multiple known respiratory pathogens in China, thereby providing effective prevention and control measures.PMID:38617014 | PMC:PMC11008481 | DOI:10.7150/ijms.93628 (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - April 15, 2024 Category: Biomedical Science Authors: Yiyin Long Yan Zheng Changlin Li Zhanjun Guo Peng Li Fuqing Zhang Wei Liu Yuliang Wang Source Type: research
Cutting Edge: First Lung Infection Permanently Enlarges Lymph Nodes and Enhances New T Cell Responses
J Immunol. 2024 Apr 15:ji2400010. doi: 10.4049/jimmunol.2400010. Online ahead of print.ABSTRACTHumans experience frequent respiratory infections. Immunology and vaccinology studies in mice are typically performed in naive specific pathogen-free animals responding to their very first respiratory challenge. We found that the first respiratory infection induces lifelong enlargement of the lung-draining mediastinal lymph nodes (medLNs). Furthermore, infection-experienced medLNs supported better naive T cell surveillance and effector responses to new unrelated infections that exhibited more biased accumulation and memory establ...
Source: Journal of Immunology - April 15, 2024 Category: Allergy & Immunology Authors: J Michael Stolley Milcah C Scott Stephen D O'Flanagan Marco K ünzli Courtney A Matson Eyob Weyu Ryan A Langlois Vaiva Vezys David Masopust Source Type: research
Interaction and Antiviral Treatment of Coinfection between SARS-CoV-2 and Influenza in Vitro
CONCLUSIONS: In coinfection, the replication of SARS-CoV-2 would be interfered by influenza H1N1. Compared with molnupiravir or baloxavir monotherapy, treatment with a combination of molnupiravir and baloxavir should be considered for early treatment in patients with SARS-CoV-2 and influenza coinfection.PMID:38621598 | DOI:10.1016/j.virusres.2024.199371 (Source: Virus Research)
Source: Virus Research - April 15, 2024 Category: Virology Authors: Danlei Liu Ka-Yi Leung Hoi-Yan Lam Ruiqi Zhang Yujing Fan Xiaochun Xie Kwok-Hung Chan Ivan Fan-Ngai Hung Source Type: research
Respiratory pathogenic microbial infections: a narrative review
This article aims to review community-acquired respiratory illnesses covering a broad spectrum of viruses, bacteria, and atypical microorganisms and focuses on the cluster prevalence of multiple known respiratory pathogens in China, thereby providing effective prevention and control measures.PMID:38617014 | PMC:PMC11008481 | DOI:10.7150/ijms.93628 (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - April 15, 2024 Category: Biomedical Science Authors: Yiyin Long Yan Zheng Changlin Li Zhanjun Guo Peng Li Fuqing Zhang Wei Liu Yuliang Wang Source Type: research
Interaction and antiviral treatment of coinfection between SARS-CoV-2 and influenza in vitro
CONCLUSIONS: In coinfection, the replication of SARS-CoV-2 would be interfered by influenza H1N1. Compared with molnupiravir or baloxavir monotherapy, treatment with a combination of molnupiravir and baloxavir should be considered for early treatment in patients with SARS-CoV-2 and influenza coinfection.PMID:38621598 | DOI:10.1016/j.virusres.2024.199371 (Source: Virus Research)
Source: Virus Research - April 15, 2024 Category: Virology Authors: Danlei Liu Ka-Yi Leung Hoi-Yan Lam Ruiqi Zhang Yujing Fan Xiaochun Xie Kwok-Hung Chan Ivan Fan-Ngai Hung Source Type: research
Respiratory pathogenic microbial infections: a narrative review
This article aims to review community-acquired respiratory illnesses covering a broad spectrum of viruses, bacteria, and atypical microorganisms and focuses on the cluster prevalence of multiple known respiratory pathogens in China, thereby providing effective prevention and control measures.PMID:38617014 | PMC:PMC11008481 | DOI:10.7150/ijms.93628 (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - April 15, 2024 Category: Biomedical Science Authors: Yiyin Long Yan Zheng Changlin Li Zhanjun Guo Peng Li Fuqing Zhang Wei Liu Yuliang Wang Source Type: research
