Isolated tongue angioedema after alteplase infusion in acute ischemic stroke
CONCLUSION: Although the incidence of alteplase-induced angiodema in these patients is rare, this case report suggests the need for routine inspection of the tongue in acute ischemic patient in treatment with alteplase infusion, especially in female patients in treatment with ACE inhibitors.PMID:34323196 | DOI:10.2174/1574886316666210728104331 (Source: Current Drug Safety)
Source: Current Drug Safety - July 29, 2021 Category: Drugs & Pharmacology Authors: Ermanno Pisani Carmen Gaudiano Alfredo Petrone Furio Stancati Antonio Siniscalchi Source Type: research

Isolated tongue angioedema after alteplase infusion in acute ischemic stroke
CONCLUSION: Although the incidence of alteplase-induced angiodema in these patients is rare, this case report suggests the need for routine inspection of the tongue in acute ischemic patient in treatment with alteplase infusion, especially in female patients in treatment with ACE inhibitors.PMID:34323196 | DOI:10.2174/1574886316666210728104331 (Source: Current Drug Safety)
Source: Current Drug Safety - July 29, 2021 Category: Drugs & Pharmacology Authors: Ermanno Pisani Carmen Gaudiano Alfredo Petrone Furio Stancati Antonio Siniscalchi Source Type: research

Isolated tongue angioedema after alteplase infusion in acute ischemic stroke
CONCLUSION: Although the incidence of alteplase-induced angiodema in these patients is rare, this case report suggests the need for routine inspection of the tongue in acute ischemic patient in treatment with alteplase infusion, especially in female patients in treatment with ACE inhibitors.PMID:34323196 | DOI:10.2174/1574886316666210728104331 (Source: Current Drug Safety)
Source: Current Drug Safety - July 29, 2021 Category: Drugs & Pharmacology Authors: Ermanno Pisani Carmen Gaudiano Alfredo Petrone Furio Stancati Antonio Siniscalchi Source Type: research

Isolated tongue angioedema after alteplase infusion in acute ischemic stroke
CONCLUSION: Although the incidence of alteplase-induced angiodema in these patients is rare, this case report suggests the need for routine inspection of the tongue in acute ischemic patient in treatment with alteplase infusion, especially in female patients in treatment with ACE inhibitors.PMID:34323196 | DOI:10.2174/1574886316666210728104331 (Source: Current Drug Safety)
Source: Current Drug Safety - July 29, 2021 Category: Drugs & Pharmacology Authors: Ermanno Pisani Carmen Gaudiano Alfredo Petrone Furio Stancati Antonio Siniscalchi Source Type: research

Isolated tongue angioedema after alteplase infusion in acute ischemic stroke
CONCLUSION: Although the incidence of alteplase-induced angiodema in these patients is rare, this case report suggests the need for routine inspection of the tongue in acute ischemic patient in treatment with alteplase infusion, especially in female patients in treatment with ACE inhibitors.PMID:34323196 | DOI:10.2174/1574886316666210728104331 (Source: Current Drug Safety)
Source: Current Drug Safety - July 29, 2021 Category: Drugs & Pharmacology Authors: Ermanno Pisani Carmen Gaudiano Alfredo Petrone Furio Stancati Antonio Siniscalchi Source Type: research

Isolated tongue angioedema after alteplase infusion in acute ischemic stroke
CONCLUSION: Although the incidence of alteplase-induced angiodema in these patients is rare, this case report suggests the need for routine inspection of the tongue in acute ischemic patient in treatment with alteplase infusion, especially in female patients in treatment with ACE inhibitors.PMID:34323196 | DOI:10.2174/1574886316666210728104331 (Source: Current Drug Safety)
Source: Current Drug Safety - July 29, 2021 Category: Drugs & Pharmacology Authors: Ermanno Pisani Carmen Gaudiano Alfredo Petrone Furio Stancati Antonio Siniscalchi Source Type: research

Isolated tongue angioedema after alteplase infusion in acute ischemic stroke
CONCLUSION: Although the incidence of alteplase-induced angiodema in these patients is rare, this case report suggests the need for routine inspection of the tongue in acute ischemic patient in treatment with alteplase infusion, especially in female patients in treatment with ACE inhibitors.PMID:34323196 | DOI:10.2174/1574886316666210728104331 (Source: Current Drug Safety)
Source: Current Drug Safety - July 29, 2021 Category: Drugs & Pharmacology Authors: Ermanno Pisani Carmen Gaudiano Alfredo Petrone Furio Stancati Antonio Siniscalchi Source Type: research

Isolated tongue angioedema after alteplase infusion in acute ischemic stroke
CONCLUSION: Although the incidence of alteplase-induced angiodema in these patients is rare, this case report suggests the need for routine inspection of the tongue in acute ischemic patient in treatment with alteplase infusion, especially in female patients in treatment with ACE inhibitors.PMID:34323196 | DOI:10.2174/1574886316666210728104331 (Source: Current Drug Safety)
Source: Current Drug Safety - July 29, 2021 Category: Drugs & Pharmacology Authors: Ermanno Pisani Carmen Gaudiano Alfredo Petrone Furio Stancati Antonio Siniscalchi Source Type: research

Isolated tongue angioedema after alteplase infusion in acute ischemic stroke
CONCLUSION: Although the incidence of alteplase-induced angiodema in these patients is rare, this case report suggests the need for routine inspection of the tongue in acute ischemic patient in treatment with alteplase infusion, especially in female patients in treatment with ACE inhibitors.PMID:34323196 | DOI:10.2174/1574886316666210728104331 (Source: Current Drug Safety)
Source: Current Drug Safety - July 29, 2021 Category: Drugs & Pharmacology Authors: Ermanno Pisani Carmen Gaudiano Alfredo Petrone Furio Stancati Antonio Siniscalchi Source Type: research

Isolated tongue angioedema after alteplase infusion in acute ischemic stroke
CONCLUSION: Although the incidence of alteplase-induced angiodema in these patients is rare, this case report suggests the need for routine inspection of the tongue in acute ischemic patient in treatment with alteplase infusion, especially in female patients in treatment with ACE inhibitors.PMID:34323196 | DOI:10.2174/1574886316666210728104331 (Source: Current Drug Safety)
Source: Current Drug Safety - July 29, 2021 Category: Drugs & Pharmacology Authors: Ermanno Pisani Carmen Gaudiano Alfredo Petrone Furio Stancati Antonio Siniscalchi Source Type: research

Combination blood pressure lowering in the presence or absence of background statin and aspirin therapy: a combined analysis of PROGRESS and ADVANCE Trials
Conclusion: BP lowering with perindopril and indapamide reduces the risk of major cardiovascular events independent of baseline use of aspirin and/or statins. (Source: Journal of Hypertension)
Source: Journal of Hypertension - July 9, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Treatment Source Type: research

The Forgotten Antiproteinuric Properties of Diuretics
Background: Although diuretics are one of the most widely used drugs by nephrologists, their antiproteinuric properties are not generally taken into consideration.Summary: Thiazide diuretics have been shown to reduce proteinuria by #x3e;35% in several prospective controlled studies, and these values are markedly increased when combined with a low-salt diet. Thiazide-like diuretics (indapamide and chlorthalidone) have shown similar effectiveness. The antiproteinuric effect of mineralocorticoid receptor antagonists (spironolactone, eplerenone, and finerenone) has been clearly established through prospective and controlled st...
Source: American Journal of Nephrology - July 7, 2021 Category: Neurology Source Type: research

The Forgotten Antiproteinuric Properties of Diuretics
Am J Nephrol. 2021 Jul 7:1-15. doi: 10.1159/000517020. Online ahead of print.ABSTRACTBACKGROUND: Although diuretics are one of the most widely used drugs by nephrologists, their antiproteinuric properties are not generally taken into consideration.SUMMARY: Thiazide diuretics have been shown to reduce proteinuria by >35% in several prospective controlled studies, and these values are markedly increased when combined with a low-salt diet. Thiazide-like diuretics (indapamide and chlorthalidone) have shown similar effectiveness. The antiproteinuric effect of mineralocorticoid receptor antagonists (spironolactone, eplerenone...
Source: American Journal of Nephrology - July 7, 2021 Category: Urology & Nephrology Authors: Hernando Trujillo Fernando Caravaca-Font án Jara Caro Enrique Morales Manuel Praga Source Type: research

The Forgotten Antiproteinuric Properties of Diuretics
Am J Nephrol. 2021 Jul 7:1-15. doi: 10.1159/000517020. Online ahead of print.ABSTRACTBACKGROUND: Although diuretics are one of the most widely used drugs by nephrologists, their antiproteinuric properties are not generally taken into consideration.SUMMARY: Thiazide diuretics have been shown to reduce proteinuria by >35% in several prospective controlled studies, and these values are markedly increased when combined with a low-salt diet. Thiazide-like diuretics (indapamide and chlorthalidone) have shown similar effectiveness. The antiproteinuric effect of mineralocorticoid receptor antagonists (spironolactone, eplerenone...
Source: American Journal of Nephrology - July 7, 2021 Category: Urology & Nephrology Authors: Hernando Trujillo Fernando Caravaca-Font án Jara Caro Enrique Morales Manuel Praga Source Type: research

The Forgotten Antiproteinuric Properties of Diuretics
Am J Nephrol. 2021 Jul 7:1-15. doi: 10.1159/000517020. Online ahead of print.ABSTRACTBACKGROUND: Although diuretics are one of the most widely used drugs by nephrologists, their antiproteinuric properties are not generally taken into consideration.SUMMARY: Thiazide diuretics have been shown to reduce proteinuria by >35% in several prospective controlled studies, and these values are markedly increased when combined with a low-salt diet. Thiazide-like diuretics (indapamide and chlorthalidone) have shown similar effectiveness. The antiproteinuric effect of mineralocorticoid receptor antagonists (spironolactone, eplerenone...
Source: American Journal of Nephrology - July 7, 2021 Category: Urology & Nephrology Authors: Hernando Trujillo Fernando Caravaca-Font án Jara Caro Enrique Morales Manuel Praga Source Type: research