Cytokine Storm Alleviated Using a Haemofilter in Veno-Venous Extracorporeal Membrane Oxygenation
Introduction: The massive release of cytokines into the bloodstream is the pathophysiological culprit of many life-threatening diseases. Cytosorb filter has lately experienced widespread use in various clinical settings. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , K. Steger, C. Heim Source Type: research
Citrate anticoagulation and systemic heparin anticoagulation during continuous renal replacement therapy among critically-ill children
CONCLUSION: RCA is a safe and effective anticoagulation method for CRRT in critically-ill children and it prolongs hemofilter survival.IMPACT: RCA is superior to systemic heparin for the prolongation of circuit survival (overall and for clotting-related loss) during CRRT. These data indicate that RCA can be used to maximize the effective delivery of CRRT in critically-ill patients admitted to the PICU. There are potential cost-saving implications from our results owing to benefits such as less circuit downtime and fewer circuit changes.PMID:38555381 | DOI:10.1038/s41390-024-03163-x (Source: Pediatric Research)
Source: Pediatric Research - March 30, 2024 Category: Pediatrics Authors: Seyma Koksal Atis Muhterem Duyu Zeynep Karakaya Alev Yilmaz Source Type: research
Citrate anticoagulation and systemic heparin anticoagulation during continuous renal replacement therapy among critically-ill children
CONCLUSION: RCA is a safe and effective anticoagulation method for CRRT in critically-ill children and it prolongs hemofilter survival.IMPACT: RCA is superior to systemic heparin for the prolongation of circuit survival (overall and for clotting-related loss) during CRRT. These data indicate that RCA can be used to maximize the effective delivery of CRRT in critically-ill patients admitted to the PICU. There are potential cost-saving implications from our results owing to benefits such as less circuit downtime and fewer circuit changes.PMID:38555381 | DOI:10.1038/s41390-024-03163-x (Source: Pediatric Research)
Source: Pediatric Research - March 30, 2024 Category: Pediatrics Authors: Seyma Koksal Atis Muhterem Duyu Zeynep Karakaya Alev Yilmaz Source Type: research
Citrate anticoagulation and systemic heparin anticoagulation during continuous renal replacement therapy among critically-ill children
CONCLUSION: RCA is a safe and effective anticoagulation method for CRRT in critically-ill children and it prolongs hemofilter survival.IMPACT: RCA is superior to systemic heparin for the prolongation of circuit survival (overall and for clotting-related loss) during CRRT. These data indicate that RCA can be used to maximize the effective delivery of CRRT in critically-ill patients admitted to the PICU. There are potential cost-saving implications from our results owing to benefits such as less circuit downtime and fewer circuit changes.PMID:38555381 | DOI:10.1038/s41390-024-03163-x (Source: Pediatric Research)
Source: Pediatric Research - March 30, 2024 Category: Pediatrics Authors: Seyma Koksal Atis Muhterem Duyu Zeynep Karakaya Alev Yilmaz Source Type: research
Effects of haemodiafiltration or haemofiltration compared with haemodialysis on prognosis in patients with end-stage renal disease: protocol an updated systematic review and meta-analysis of randomised trials with trial sequential analysis
Introduction
Haemodialysis is the most common treatment option for patients with life-sustaining end-stage kidney disease (ESKD). In recent years, haemodiafiltration or haemofiltration has been widely used in patients with ESKD, and there are still conflicting findings as to whether both are superior to traditional haemodialysis. This systematic review and meta-analysis were designed to determine whether haemodiafiltration or haemofiltration is more effective than haemodialysis in reducing all-cause mortality risk in patients with ESKD.
Methods and analysis
We will perform a systematic PubMed, Embase, Cochrane Central Reg...
Source: BMJ Open - March 23, 2024 Category: General Medicine Authors: Zhang, F., Liao, J., Bai, Y., Zhang, Z., Huang, L., Zhong, Y. Tags: Open access, Renal medicine Source Type: research
National study on the risks of COVID-19 infection for paediatric kidney transplant recipients: a retrospective, cross-sectional study
Conclusion
We report 10.4% of the UK paediatric renal transplantation population had documented COVID-19 infections with positive SARS-CoV-2 PCR RNA with 28% of those affected requiring hospitalisation. The increased incidence of AKI, particularly after the first wave of the COVID-19 pandemic, was possibly due to increased testing. There was low morbidity and mortality compared with the adult population. (Source: Archives of Disease in Childhood)
Source: Archives of Disease in Childhood - March 19, 2024 Category: Pediatrics Authors: Withers, C., Patel, R., Reynolds, B. C., Christian, M., Muorah, M., Tse, Y., Edwards, L., Yadav, P., Haq, S., Hegde, S., Callaghan, C. J., Bamford, A., Marks, S. D. Tags: COVID-19 Original research Source Type: research
Comparison of disease and economic burden between MRSA infection and MRSA colonization in a university hospital: a retrospective data integration study
ConclusionsMRSA infection was associated with longer length of stay and higher hospital charges than both MSSA infection and MRSA colonization. Furthermore, hemodialysis or hemofiltration was identified as a common underlying factor contributing to increased length of stay and hospital charges. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - February 29, 2024 Category: Infectious Diseases Source Type: research
A Retrospective Study on the Start and End of Continuous Hemodialysis using a Polymethylmethacrylate Hemofilter for Severe Acute Pancreatitis
Conclusion Prognostic factor scores of the Japanese severity criteria and LIS, as well as the KDIGO stage, are valuable indicators for determining the start and end of PMMA-CHD therapy.PMID:38220199 | DOI:10.2169/internalmedicine.2708-23 (Source: Internal Medicine)
Source: Internal Medicine - January 14, 2024 Category: Internal Medicine Authors: Kiyohiko Kinjoh Ryoji Nagamura Yutaka Sakuda Source Type: research
Immunologic Effects of Heparin Associated With Hemodialysis: Focus on Heparin-Induced Thrombocytopenia
Intermittent hemodialysis (HD) is almost invariably performed with heparin, and thus HD patients are at risk of developing the immune-mediated adverse effect heparin-induced thrombocytopenia (HIT), caused by anti-platelet factor 4/heparin IgG, which strongly activates platelets. HIT patients develop hypercoagulability with greatly increased risk of thrombosis, both venous and arterial. Certain HIT-associated complications are more likely to develop among HD patients, including hemofilter thrombosis despite heparin, intravascular catheter and/or arteriovenous fistula-associated thrombosis, post-heparin bolus anaphylactoid/a...
Source: Seminars in Nephrology - January 8, 2024 Category: Urology & Nephrology Authors: Theodore E. Warkentin Source Type: research
Rescue strategies for valproic acid overdose poisoning: Case series and literature review
This article details the three cases of acute poisoning from VPA. The fundamental approach to treatment employs HP assisted by blood concentration monitoring to alleviate shock and stabilize hemodynamics. This investigation presents guidance for the treatment and management of acute poisoning with VPA in clinical settings. (Source: Clinical Case Reports)
Source: Clinical Case Reports - December 28, 2023 Category: General Medicine Authors: Renzhu Liu,
Lu Xiao,
Yixiang Hu,
Qingzi Yan,
Xiang Liu Tags: CASE SERIES Source Type: research
Effects of enhanced adsorption haemofiltration versus haemoadsorption in severe, refractory septic shock with high levels of endotoxemia: the ENDoX bicentric, randomized, controlled trial
Endotoxin adsorption is a promising but controversial therapy in severe, refractory septic shock and conflicting results exist on the effective capacity of available devices to reduce circulating endotoxin and... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - December 14, 2023 Category: Intensive Care Authors: Pedro David Wendel-Garcia, Barbara Eberle, Eva-Maria Kleinert, Matthias Peter Hilty, Stephan Blumenthal, Katharina Spanaus, Patricia Fodor and Marco Maggiorini Tags: Research Source Type: research
Sensors, Vol. 23, Pages 9792: Simulation and Analysis of Anodized Aluminum Oxide Membrane Degradation
ado-Alvarado
Microelectromechanical systems (MEMS)-based filter with microchannels enables the removal of various microorganisms, including viruses and bacteria, from fluids. Membranes with porous channels can be used as filtration interfaces in MEMS hemofilters or mini-dialyzers. The main problems associated with the filtration process are optimization of membrane geometry and fouling. A nanoporous aluminum oxide membrane was fabricated using an optimized two-step anodization process. Computational strength modeling and analysis of the membrane with specified parameters were performed using the ANSYS structural module...
Source: Sensors - December 13, 2023 Category: Biotechnology Authors: Saher Manzoor Faheem Qasim Muhammad Waseem Ashraf Shahzadi Tayyaba Nimra Tariq Agust ín L. Herrera-May Enrique Delgado-Alvarado Tags: Article Source Type: research
Removal characteristics of presepsin by operating conditions and hemofilter
AbstractPresepsin, which is used as a biomarker for sepsis, is thought to be removed by dialysis, but the actual removal properties of dialysis are unknown. We investigated the presepsin removal properties of continuous hemodiafiltration using the high concentration of presepsin from human plasma drained by plasma exchange. Each solution in plasma exchange was connected to a continuous hemodiafiltration blood circuit and circulated at 4 conditions. The results show that presepsin was confirmed to be removed more efficiently in hemofiltration than in hemodialysis. In addition, when using a polymethylmethacrylate hemofilter ...
Source: Journal of Artificial Organs - December 5, 2023 Category: Transplant Surgery Source Type: research
The gap between predictive equations and measured resting energy expenditure during continuous venovenous hemofiltration
Rationale: Predicted resting energy expenditure (pREE) calculated with equations has shown a large disagreement compared to measured REE (mREE) with indirect calorimetry, as a large variety of parameters influences the metabolic rate of critically ill patients. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: W. Pieteraerens, J. Jonckheer, E. De Waele, D. Goethals Source Type: research
