A case of infection-induced thrombotic thrombocytopenic purpura
CONCLUSION: TTP is an acute severe disease with complex etiology, abrupt onset, and dangerous conditions. In this patient with TTP, an important cause of the disease may have been an acute gastrointestinal infection. The plasma examination in another hospital revealed positive results for ADAMTS13 inhibitors, providing strong evidence for the diagnosis of this case. Multiple plasma exchanges and glucocorticoids yielded favorable treatment results and were critical measures of successful treatment of TTP.PMID:37182863 | DOI:10.3233/CH-231784 (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - May 14, 2023 Category: Hematology Authors: Shaohua Cui Chaoyue Liang Lixia Geng Source Type: research

A case of infection-induced thrombotic thrombocytopenic purpura
CONCLUSION: TTP is an acute severe disease with complex etiology, abrupt onset, and dangerous conditions. In this patient with TTP, an important cause of the disease may have been an acute gastrointestinal infection. The plasma examination in another hospital revealed positive results for ADAMTS13 inhibitors, providing strong evidence for the diagnosis of this case. Multiple plasma exchanges and glucocorticoids yielded favorable treatment results and were critical measures of successful treatment of TTP.PMID:37182863 | DOI:10.3233/CH-231784 (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - May 14, 2023 Category: Hematology Authors: Shaohua Cui Chaoyue Liang Lixia Geng Source Type: research

A case of infection-induced thrombotic thrombocytopenic purpura
CONCLUSION: TTP is an acute severe disease with complex etiology, abrupt onset, and dangerous conditions. In this patient with TTP, an important cause of the disease may have been an acute gastrointestinal infection. The plasma examination in another hospital revealed positive results for ADAMTS13 inhibitors, providing strong evidence for the diagnosis of this case. Multiple plasma exchanges and glucocorticoids yielded favorable treatment results and were critical measures of successful treatment of TTP.PMID:37182863 | DOI:10.3233/CH-231784 (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - May 14, 2023 Category: Hematology Authors: Shaohua Cui Chaoyue Liang Lixia Geng Source Type: research

A case of infection-induced thrombotic thrombocytopenic purpura
CONCLUSION: TTP is an acute severe disease with complex etiology, abrupt onset, and dangerous conditions. In this patient with TTP, an important cause of the disease may have been an acute gastrointestinal infection. The plasma examination in another hospital revealed positive results for ADAMTS13 inhibitors, providing strong evidence for the diagnosis of this case. Multiple plasma exchanges and glucocorticoids yielded favorable treatment results and were critical measures of successful treatment of TTP.PMID:37182863 | DOI:10.3233/CH-231784 (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - May 14, 2023 Category: Hematology Authors: Shaohua Cui Chaoyue Liang Lixia Geng Source Type: research

A case of infection-induced thrombotic thrombocytopenic purpura
CONCLUSION: TTP is an acute severe disease with complex etiology, abrupt onset, and dangerous conditions. In this patient with TTP, an important cause of the disease may have been an acute gastrointestinal infection. The plasma examination in another hospital revealed positive results for ADAMTS13 inhibitors, providing strong evidence for the diagnosis of this case. Multiple plasma exchanges and glucocorticoids yielded favorable treatment results and were critical measures of successful treatment of TTP.PMID:37182863 | DOI:10.3233/CH-231784 (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - May 14, 2023 Category: Hematology Authors: Shaohua Cui Chaoyue Liang Lixia Geng Source Type: research

A case of infection-induced thrombotic thrombocytopenic purpura
CONCLUSION: TTP is an acute severe disease with complex etiology, abrupt onset, and dangerous conditions. In this patient with TTP, an important cause of the disease may have been an acute gastrointestinal infection. The plasma examination in another hospital revealed positive results for ADAMTS13 inhibitors, providing strong evidence for the diagnosis of this case. Multiple plasma exchanges and glucocorticoids yielded favorable treatment results and were critical measures of successful treatment of TTP.PMID:37182863 | DOI:10.3233/CH-231784 (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - May 14, 2023 Category: Hematology Authors: Shaohua Cui Chaoyue Liang Lixia Geng Source Type: research

A case of infection-induced thrombotic thrombocytopenic purpura
CONCLUSION: TTP is an acute severe disease with complex etiology, abrupt onset, and dangerous conditions. In this patient with TTP, an important cause of the disease may have been an acute gastrointestinal infection. The plasma examination in another hospital revealed positive results for ADAMTS13 inhibitors, providing strong evidence for the diagnosis of this case. Multiple plasma exchanges and glucocorticoids yielded favorable treatment results and were critical measures of successful treatment of TTP.PMID:37182863 | DOI:10.3233/CH-231784 (Source: Clinical Hemorheology and Microcirculation)
Source: Clinical Hemorheology and Microcirculation - May 14, 2023 Category: Hematology Authors: Shaohua Cui Chaoyue Liang Lixia Geng Source Type: research

Hemofiltration as an alternative for IL-6 inhibitors in COVID-19 cytokines storm associated with underlaying bacterial infections: A review Article
Infect Disord Drug Targets. 2023 May 2. doi: 10.2174/1871526523666230502143507. Online ahead of print.ABSTRACTSARS-CoV-2 causes mostly mild cases. However, a considerable number of patients develop fatal acute respiratory distress syndrome due to the cytokine storm and imbalanced immune response. Several therapies depending on immunomodulation have been used, including glucocorticoids and IL-6 blockers. However, their efficacy is not perfect with all patients and patients with concomitant bacterial infections and sepsis. Accordingly, studies on different immunomodulators, including extracorporeal techniques, are crucial to...
Source: Infectious Disorders Drug Targets - May 4, 2023 Category: Infectious Diseases Authors: Samy Zaky Mohamed El Badry Hoda A Makhlouf Sherief M Abd-Elsalam Tarik S Sarhan Noha H Eltaweel Heba Aly Akram Abdelbary Ahmed Said Mohammed Hamdy Farouk Amin Abdelbaki Hanaa Fathelbab Reham Hammad Fathiya El-Raey Source Type: research

Hemofiltration as an alternative for IL-6 inhibitors in COVID-19 cytokines storm associated with underlaying bacterial infections: A review Article
Infect Disord Drug Targets. 2023 May 2. doi: 10.2174/1871526523666230502143507. Online ahead of print.ABSTRACTSARS-CoV-2 causes mostly mild cases. However, a considerable number of patients develop fatal acute respiratory distress syndrome due to the cytokine storm and imbalanced immune response. Several therapies depending on immunomodulation have been used, including glucocorticoids and IL-6 blockers. However, their efficacy is not perfect with all patients and patients with concomitant bacterial infections and sepsis. Accordingly, studies on different immunomodulators, including extracorporeal techniques, are crucial to...
Source: Infectious Disorders Drug Targets - May 4, 2023 Category: Infectious Diseases Authors: Samy Zaky Mohamed El Badry Hoda A Makhlouf Sherief M Abd-Elsalam Tarik S Sarhan Noha H Eltaweel Heba Aly Akram Abdelbary Ahmed Said Mohammed Hamdy Farouk Amin Abdelbaki Hanaa Fathelbab Reham Hammad Fathiya El-Raey Source Type: research

Hemofiltration as an alternative for IL-6 inhibitors in COVID-19 cytokines storm associated with underlaying bacterial infections: A review Article
Infect Disord Drug Targets. 2023 May 2. doi: 10.2174/1871526523666230502143507. Online ahead of print.ABSTRACTSARS-CoV-2 causes mostly mild cases. However, a considerable number of patients develop fatal acute respiratory distress syndrome due to the cytokine storm and imbalanced immune response. Several therapies depending on immunomodulation have been used, including glucocorticoids and IL-6 blockers. However, their efficacy is not perfect with all patients and patients with concomitant bacterial infections and sepsis. Accordingly, studies on different immunomodulators, including extracorporeal techniques, are crucial to...
Source: Infectious Disorders Drug Targets - May 4, 2023 Category: Infectious Diseases Authors: Samy Zaky Mohamed El Badry Hoda A Makhlouf Sherief M Abd-Elsalam Tarik S Sarhan Noha H Eltaweel Heba Aly Akram Abdelbary Ahmed Said Mohammed Hamdy Farouk Amin Abdelbaki Hanaa Fathelbab Reham Hammad Fathiya El-Raey Source Type: research

Hemofiltration as an alternative for IL-6 inhibitors in COVID-19 cytokines storm associated with underlaying bacterial infections: A review Article
Infect Disord Drug Targets. 2023 May 2. doi: 10.2174/1871526523666230502143507. Online ahead of print.ABSTRACTSARS-CoV-2 causes mostly mild cases. However, a considerable number of patients develop fatal acute respiratory distress syndrome due to the cytokine storm and imbalanced immune response. Several therapies depending on immunomodulation have been used, including glucocorticoids and IL-6 blockers. However, their efficacy is not perfect with all patients and patients with concomitant bacterial infections and sepsis. Accordingly, studies on different immunomodulators, including extracorporeal techniques, are crucial to...
Source: Infectious Disorders Drug Targets - May 4, 2023 Category: Infectious Diseases Authors: Samy Zaky Mohamed El Badry Hoda A Makhlouf Sherief M Abd-Elsalam Tarik S Sarhan Noha H Eltaweel Heba Aly Akram Abdelbary Ahmed Said Mohammed Hamdy Farouk Amin Abdelbaki Hanaa Fathelbab Reham Hammad Fathiya El-Raey Source Type: research

Blood Purification with oXiris © in Critically Ill Children with Vasoplegic Shock
Conclusion: Hemofiltration and extracorporeal blood purification with oXiris © can be used in pediatric patients with vasoplegic shock with rapid improvement in hemodynamics in selected patients.Blood Purif (Source: Blood Purification)
Source: Blood Purification - April 27, 2023 Category: Hematology Source Type: research

Extracorporeal blood purification benefits in post-caesarean patient with severe acute respiratory distress syndrome due to miliary tuberculosis: a case report
ConclusionThe bacterial infection of tuberculosis, acute respiratory distress syndrome, and the stress response from the caesarean section contributed to the high levels of cytokines, which correlated with the patient ’s severe inflammatory condition. The cytokine levels were greatly reduced after the blood purification procedure and this might be associated with the patient’s clinical improvement. Extracorporeal blood purification could help to disrupt the vicious cycle of inflammation. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - April 12, 2023 Category: General Medicine Source Type: research