Minimized Hemodiafiltration for Extracorporeal Membrane Oxygenation in Infants
CONCLUSION: There were no complications with the minimized HDF system in all 15 applications. It allows safe patient volume management when treating infants with ECMO, with effective elimination of urinary substances.PMID:37037222 | DOI:10.1055/s-0043-1766107 (Source: The Thoracic and Cardiovascular Surgeon)
Source: The Thoracic and Cardiovascular Surgeon - April 10, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Nicola Kwapil Andreas Teske Sven Dittrich Robert Blumauer Michela Cuomo Ariawan Purbojo Frank M ünch Source Type: research
Minimized Hemodiafiltration for Extracorporeal Membrane Oxygenation in Infants
CONCLUSION: There were no complications with the minimized HDF system in all 15 applications. It allows safe patient volume management when treating infants with ECMO, with effective elimination of urinary substances.PMID:37037222 | DOI:10.1055/s-0043-1766107 (Source: The Thoracic and Cardiovascular Surgeon)
Source: The Thoracic and Cardiovascular Surgeon - April 10, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Nicola Kwapil Andreas Teske Sven Dittrich Robert Blumauer Michela Cuomo Ariawan Purbojo Frank M ünch Source Type: research
Minimized Hemodiafiltration for Extracorporeal Membrane Oxygenation in Infants
Conclusion There were no complications with the minimized HDF system in all 15 applications. It allows safe patient volume management when treating infants with ECMO, with effective elimination of urinary substances. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | open access Full text (Source: The Thoracic and Cardiovascular Surgeon)
Source: The Thoracic and Cardiovascular Surgeon - April 10, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Kwapil, Nicola Teske, Andreas Dittrich, Sven Blumauer, Robert Cuomo, Michela Purbojo, Ariawan M ünch, Frank Tags: Pediatric and Congenital Cardiology Source Type: research
Ex-situ Normothermic ECMO Technology with Continuous Perfusate Hemofiltration for Organ Management
We present a model of NESHP using continuous perfusate hemofiltration (cPH) that resulted in successful orthotopic heart transplantation (HTx). (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2023 Category: Transplant Surgery Authors: T. Lesbekov, R. Kaliyev, Z. Nurmykhametova, L. Faizov, A. Medressova, M. Aripov, N. Tanaliyev, E. Zuparov, A. Iskakova, Y. Pya Tags: (869) Source Type: research
IJERPH, Vol. 20, Pages 5021: Case Report: Acute Intoxication from Phosphine Inhalation
Xiangdong Jian
Aluminum phosphide is a highly effective insecticide for fumigation in granaries and is often used in rural grain storage. However, people’s awareness of its toxicity is not strong. A case of acute inhalation toxicity of phosphine caused by the use of aluminum phosphide to fumigate a granary is reported here. The case presented with aspiration pneumonia and acute left heart failure. The patient was cured using comprehensive life support treatment, including respiratory support, antiarrhythmic treatment, and blood pressure maintenance with vasoactive drugs. There is no specific antidote f...
Source: International Journal of Environmental Research and Public Health - March 12, 2023 Category: Environmental Health Authors: Longke Shi Tianzi Jian Yiming Tao Yaqian Li Guangcai Yu Liwen Zhao Zixin Wen Baotian Kan Xiangdong Jian Tags: Case Report Source Type: research
Hypertriglyceridemia as a Cause of Continuous Renal Replacement Therapy Circuit Clotting: A Case Series
Conclusion: Due to the propensity of propofol use for critically ill patients in intensive care units, and the rather common occurrence of CRRT circuit clotting, hypertriglyceridemia may be underappreciated and undiagnosed. The exact pathophysiology behind hypertriglyceridemia-induced CRRT clotting has not been fully elucidated, although there are some hypotheses which include fibrin and fat droplet deposition (identified after electron microscopic examination of the hemofilter), increased blood viscosity, and development of a procoagulant state. Premature clotting poses a multitude of problems including inadequate treatme...
Source: Blood Purification - March 10, 2023 Category: Hematology Source Type: research
Extremely high unbound flucloxacillin concentrations in a patient with acute septic renal failure during continuous venovenous hemofiltration: Therapeutic drug monitoring to optimize treatment
Int J Clin Pharmacol Ther. 2023 Mar 5. doi: 10.5414/CP204313. Online ahead of print.ABSTRACTA 75-year-old female orthopedic patient with spondylodiscitis was admitted to the intensive care unit, where she developed severe acute renal injury (AKI) due to a Staphylococcus aureus bloodstream infection. Continuous venovenous hemofiltration (CVVH) was initiated as renal replacement therapy. According to physician experience and based on (inter)national guidelines and the severity of the infection, treatment with intravenous (IV) flucloxacillin at an initial continuous dose of 9 g/24h was started. The dose was increased to 12 g/...
Source: Clinical Pharmacology and Therapeutics - March 5, 2023 Category: Drugs & Pharmacology Authors: Evine M Appelman Elisabeth A Wammes van-der-Heijden Sjoerd D Meenks Paddy K C Janssen Jos L M L le Noble Source Type: research
Extremely high unbound flucloxacillin concentrations in a patient with acute septic renal failure during continuous venovenous hemofiltration: Therapeutic drug monitoring to optimize treatment
Int J Clin Pharmacol Ther. 2023 Mar 5. doi: 10.5414/CP204313. Online ahead of print.ABSTRACTA 75-year-old female orthopedic patient with spondylodiscitis was admitted to the intensive care unit, where she developed severe acute renal injury (AKI) due to a Staphylococcus aureus bloodstream infection. Continuous venovenous hemofiltration (CVVH) was initiated as renal replacement therapy. According to physician experience and based on (inter)national guidelines and the severity of the infection, treatment with intravenous (IV) flucloxacillin at an initial continuous dose of 9 g/24h was started. The dose was increased to 12 g/...
Source: International Journal of Clinical Pharmacology and Therapeutics - March 5, 2023 Category: Drugs & Pharmacology Authors: Evine M Appelman Elisabeth A Wammes van-der-Heijden Sjoerd D Meenks Paddy K C Janssen Jos L M L le Noble Source Type: research
Extremely high unbound flucloxacillin concentrations in a patient with acute septic renal failure during continuous venovenous hemofiltration: Therapeutic drug monitoring to optimize treatment
Int J Clin Pharmacol Ther. 2023 Mar 5. doi: 10.5414/CP204313. Online ahead of print.ABSTRACTA 75-year-old female orthopedic patient with spondylodiscitis was admitted to the intensive care unit, where she developed severe acute renal injury (AKI) due to a Staphylococcus aureus bloodstream infection. Continuous venovenous hemofiltration (CVVH) was initiated as renal replacement therapy. According to physician experience and based on (inter)national guidelines and the severity of the infection, treatment with intravenous (IV) flucloxacillin at an initial continuous dose of 9 g/24h was started. The dose was increased to 12 g/...
Source: Clinical Pharmacology and Therapeutics - March 5, 2023 Category: Drugs & Pharmacology Authors: Evine M Appelman Elisabeth A Wammes van-der-Heijden Sjoerd D Meenks Paddy K C Janssen Jos L M L le Noble Source Type: research
Extremely high unbound flucloxacillin concentrations in a patient with acute septic renal failure during continuous venovenous hemofiltration: Therapeutic drug monitoring to optimize treatment
Int J Clin Pharmacol Ther. 2023 Mar 5. doi: 10.5414/CP204313. Online ahead of print.ABSTRACTA 75-year-old female orthopedic patient with spondylodiscitis was admitted to the intensive care unit, where she developed severe acute renal injury (AKI) due to a Staphylococcus aureus bloodstream infection. Continuous venovenous hemofiltration (CVVH) was initiated as renal replacement therapy. According to physician experience and based on (inter)national guidelines and the severity of the infection, treatment with intravenous (IV) flucloxacillin at an initial continuous dose of 9 g/24h was started. The dose was increased to 12 g/...
Source: International Journal of Clinical Pharmacology and Therapeutics - March 5, 2023 Category: Drugs & Pharmacology Authors: Evine M Appelman Elisabeth A Wammes van-der-Heijden Sjoerd D Meenks Paddy K C Janssen Jos L M L le Noble Source Type: research
Extremely high unbound flucloxacillin concentrations in a patient with acute septic renal failure during continuous venovenous hemofiltration: Therapeutic drug monitoring to optimize treatment
Int J Clin Pharmacol Ther. 2023 Mar 5. doi: 10.5414/CP204313. Online ahead of print.ABSTRACTA 75-year-old female orthopedic patient with spondylodiscitis was admitted to the intensive care unit, where she developed severe acute renal injury (AKI) due to a Staphylococcus aureus bloodstream infection. Continuous venovenous hemofiltration (CVVH) was initiated as renal replacement therapy. According to physician experience and based on (inter)national guidelines and the severity of the infection, treatment with intravenous (IV) flucloxacillin at an initial continuous dose of 9 g/24h was started. The dose was increased to 12 g/...
Source: Clinical Pharmacology and Therapeutics - March 5, 2023 Category: Drugs & Pharmacology Authors: Evine M Appelman Elisabeth A Wammes van-der-Heijden Sjoerd D Meenks Paddy K C Janssen Jos L M L le Noble Source Type: research
Ceftaroline and Avibactam Removal by Continuous Renal Replacement Therapies: An in vitro Study
Discussion: Avibactam and ceftaroline are extensively removed through the polysulfone membrane, and a dose adjustment may be recommended for patients under CRRT to ensure pharmacodynamic target achievement.Blood Purif (Source: Blood Purification)
Source: Blood Purification - March 1, 2023 Category: Hematology Source Type: research
Customized Citrate Anticoagulation versus No Anticoagulant in Continuous Venovenous Hemofiltration in Critically Ill Patients with Acute Kidney Injury: A Prospective Randomized Controlled Trial
Conclusion: Customized citrate-based replacement solution improved filter survival in CVVH compared to anticoagulant-free strategy. This regimen is safe, feasible, and suitable for low- to middle-income countries.Blood Purif (Source: Blood Purification)
Source: Blood Purification - March 1, 2023 Category: Hematology Source Type: research
Abstract No. 547 Heparin Reversal with Protamine Sulfate after Percutaneous Hepatic Perfusion (PHP): How Much Is Too Much?
Percutaneous hepatic perfusion (PHP) is a palliative intraarterial therapy approach for unresectable hepatic malignancies. During PHP, high dose chemotherapeutic melphalan is saturating the liver parenchyma and an extracorporeal hemofiltration extracts excess melphalan. Blood clotting in the extracorporeal filter system is prevented by administering unfractionated heparin (UFH), which can be reversed with protamine after the procedure. Aim of this retrospective two-center-study was to analyze the potential effect of UFH reversal with protamine on complication rates following PHP. (Source: Journal of Vascular and Interventi...
Source: Journal of Vascular and Interventional Radiology : JVIR - February 24, 2023 Category: Radiology Authors: C. Dewald, L. Becker, F. Wacker, A. Vogel, R. Bruening, J. Hinrichs Source Type: research
Lactic acidosis after allogeneic hematopoietic stem cell transplantation potentially related to letermovir
Br J Clin Pharmacol. 2023 Feb 7. doi: 10.1111/bcp.15686. Online ahead of print.ABSTRACTA 53-year-old woman with a history of acute myeloid leukemia received a second allogenic hematopoietic stem cell transplant (HSCT) and was prescribed, among other medications, acyclovir and letermovir (480 mg daily oral dose) for prophylaxis of respectively herpes simplex and cytomegalovirus infection. The patient was admitted in the intensive care unit (ICU) for dyspnoea and oliguria. Laboratory investigations revealed acute kidney injury, but also a severe and progressive lactic acidosis. Liver function tests were within normal range. ...
Source: Herpes - February 7, 2023 Category: Infectious Diseases Authors: B érénice Manczak Marie-Cl émence Verdier Joseph P Dewulf Florian Lemaitre Vincent Haufroid Philippe Hantson Source Type: research
