Retraction Note: The effects of pentoxifylline on circulating adhesion molecules in critically ill patients with acute renal failure treated by continuous veno-venous hemofiltration
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - July 25, 2023 Category: Intensive Care Source Type: research
Anti-Xa level monitoring of low-molecular-weight heparin during intermittent venovenous hemofiltration
This study aimed to evaluate the clinical use of the anti-factor Xa level (anti-Xa) for monitoring LMWH anticoagulant levels during intermittent venovenous hemofiltration (IVVHF). This prospective observational study enrolled patients who required IVVHF for renal failure in Beijing Hospital between May 2019 and February 2021. The LMWH anticoagulation was assessed by the coagulation grade of the filter and line. One hundred and ten participants were included. There were 90 patients with a filter and line coagulation grade of ≤ 1 and 20 patients with grade> 1. The anti-Xa level of 0.2 IU/mL was a critical value. The mul...
Source: Annals of Hematology - July 3, 2023 Category: Hematology Source Type: research
Comparison of the cytokine adsorption ability in continuous renal replacement therapy using polyethyleneimine-coated polyacrylonitrile (AN69ST) or polymethylmethacrylate (PMMA) hemofilters: a pilot single-center open-label randomized control trial
ConclusionAN69ST and PMMA membranes have different cytokine CHA in patients with sepsis. Therefore, these two hemofilters may have to be used depending on the target cytokine.Trial registration number: This study was registered in the University Hospital Medical Information Network on November 1, 2017 (Trial No: UMIN000029450,https://center6.umin.ac.jp). (Source: European Journal of Medical Research)
Source: European Journal of Medical Research - June 30, 2023 Category: Research Source Type: research
Hypertriglyceridemic pancreatitis managed with heparin and insulin: a case report
ConclusionSince our findings are consistent with a prior randomized controlled trial and compilation of case reports, it would strengthen the evidence for safety and efficacy of insulin and heparin therapy. This therapy, which is the only available therapy in most countries of our continent, would decrease most of the complications of hypertriglyceridemic pancreatitis that we face. We believe, our report would be a wake-up call for researchers and clinicians in our continent to change their practice and strengthen the evidence for the treatment. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - June 20, 2023 Category: General Medicine Source Type: research
Update on the Role of Polymethylmethacrylate Membrane Hemofilter in Acute and Chronic Renal Dysfunction
Contrib Nephrol. 2023 Jun 1;200:1-10. doi: 10.1159/000530476. Online ahead of print.ABSTRACTDespite recent technical advances in dialysis care over the past decades, the mortality rate of critically ill patients with acute kidney injury (AKI) requiring dialysis and of chronic kidney disease (CKD) remains unacceptably high. Several preclinical studies have increased our knowledge of the principal mechanisms involved in the pathophysiology of AKI and CKD. Additionally, the development of efficient and specific compensatory sorbent systems in renal replacement therapy to remove unwanted compounds has created the possibility t...
Source: Contributions to Nephrology - June 1, 2023 Category: Urology & Nephrology Authors: Alessandra Stasi Rossana Franzin Rosa Losapio Carlo Alfieri Loreto Gesualdo Giuseppe Castellano Source Type: research
