Aminoglycoside Pharmacokinetics in Critically Ill Patients Undergoing Continuous Renal Replacement Therapy
CONCLUSION AND RELEVANCE: Critically ill oncology patients undergoing CRRT exhibited reduced clearance and expanded Vd that was not significantly different between CRRT modalities. Current dosing regimens led to low peak concentrations and poor attainment of pharmacokinetic targets.PMID:36062536 | DOI:10.1177/10600280221120600 (Source: The Annals of Pharmacotherapy)
Source: The Annals of Pharmacotherapy - September 5, 2022 Category: Drugs & Pharmacology Authors: Chelsea K Krueger Jeffrey J Bruno Frank P Tverdek Mike Hernandez Ala Abudayyeh Source Type: research
Aminoglycoside Pharmacokinetics in Critically Ill Patients Undergoing Continuous Renal Replacement Therapy
CONCLUSION AND RELEVANCE: Critically ill oncology patients undergoing CRRT exhibited reduced clearance and expanded Vd that was not significantly different between CRRT modalities. Current dosing regimens led to low peak concentrations and poor attainment of pharmacokinetic targets.PMID:36062536 | DOI:10.1177/10600280221120600 (Source: The Annals of Pharmacotherapy)
Source: The Annals of Pharmacotherapy - September 5, 2022 Category: Drugs & Pharmacology Authors: Chelsea K Krueger Jeffrey J Bruno Frank P Tverdek Mike Hernandez Ala Abudayyeh Source Type: research
Circuit haemodynamics during non-citrate and regional citrate continuous renal replacement, and impact of blood flow on filter life
CONCLUSIONS: High-Qb RCA-CRRT was associated with greater access dysfunction, earlier filter loss and increased haemodynamic impacts of access dysfunction, suggesting low-Qb RCA-CRRT may improve circuit mechanics, function and longevity.PMID:36036083 | DOI:10.1177/03913988221118585 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - August 29, 2022 Category: Transplant Surgery Authors: Benjamin Sansom Andrew Udy Shyamala Sriram Jeffrey Presneill Rinaldo Bellomo Source Type: research
Circuit haemodynamics during non-citrate and regional citrate continuous renal replacement, and impact of blood flow on filter life
CONCLUSIONS: High-Qb RCA-CRRT was associated with greater access dysfunction, earlier filter loss and increased haemodynamic impacts of access dysfunction, suggesting low-Qb RCA-CRRT may improve circuit mechanics, function and longevity.PMID:36036083 | DOI:10.1177/03913988221118585 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - August 29, 2022 Category: Transplant Surgery Authors: Benjamin Sansom Andrew Udy Shyamala Sriram Jeffrey Presneill Rinaldo Bellomo Source Type: research
Circuit haemodynamics during non-citrate and regional citrate continuous renal replacement, and impact of blood flow on filter life
CONCLUSIONS: High-Qb RCA-CRRT was associated with greater access dysfunction, earlier filter loss and increased haemodynamic impacts of access dysfunction, suggesting low-Qb RCA-CRRT may improve circuit mechanics, function and longevity.PMID:36036083 | DOI:10.1177/03913988221118585 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - August 29, 2022 Category: Transplant Surgery Authors: Benjamin Sansom Andrew Udy Shyamala Sriram Jeffrey Presneill Rinaldo Bellomo Source Type: research
Circuit haemodynamics during non-citrate and regional citrate continuous renal replacement, and impact of blood flow on filter life
CONCLUSIONS: High-Qb RCA-CRRT was associated with greater access dysfunction, earlier filter loss and increased haemodynamic impacts of access dysfunction, suggesting low-Qb RCA-CRRT may improve circuit mechanics, function and longevity.PMID:36036083 | DOI:10.1177/03913988221118585 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - August 29, 2022 Category: Transplant Surgery Authors: Benjamin Sansom Andrew Udy Shyamala Sriram Jeffrey Presneill Rinaldo Bellomo Source Type: research
Circuit haemodynamics during non-citrate and regional citrate continuous renal replacement, and impact of blood flow on filter life
CONCLUSIONS: High-Qb RCA-CRRT was associated with greater access dysfunction, earlier filter loss and increased haemodynamic impacts of access dysfunction, suggesting low-Qb RCA-CRRT may improve circuit mechanics, function and longevity.PMID:36036083 | DOI:10.1177/03913988221118585 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - August 29, 2022 Category: Transplant Surgery Authors: Benjamin Sansom Andrew Udy Shyamala Sriram Jeffrey Presneill Rinaldo Bellomo Source Type: research
Circuit haemodynamics during non-citrate and regional citrate continuous renal replacement, and impact of blood flow on filter life
CONCLUSIONS: High-Qb RCA-CRRT was associated with greater access dysfunction, earlier filter loss and increased haemodynamic impacts of access dysfunction, suggesting low-Qb RCA-CRRT may improve circuit mechanics, function and longevity.PMID:36036083 | DOI:10.1177/03913988221118585 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - August 29, 2022 Category: Transplant Surgery Authors: Benjamin Sansom Andrew Udy Shyamala Sriram Jeffrey Presneill Rinaldo Bellomo Source Type: research
Circuit haemodynamics during non-citrate and regional citrate continuous renal replacement, and impact of blood flow on filter life
CONCLUSIONS: High-Qb RCA-CRRT was associated with greater access dysfunction, earlier filter loss and increased haemodynamic impacts of access dysfunction, suggesting low-Qb RCA-CRRT may improve circuit mechanics, function and longevity.PMID:36036083 | DOI:10.1177/03913988221118585 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - August 29, 2022 Category: Transplant Surgery Authors: Benjamin Sansom Andrew Udy Shyamala Sriram Jeffrey Presneill Rinaldo Bellomo Source Type: research
Effects of Continuous Blood Purification without Heparin on Strem-1, NSE, and IL-10 Levels In Patients With Sepsis
Cell Mol Biol (Noisy-le-grand). 2022 Apr 30;68(4):178-187. doi: 10.14715/cmb/2022.68.4.21.ABSTRACTOne of the most common causes of mortality and disability across the world is sepsis, a condition marked by an abnormal immunological reaction in the body. The prognosis of patients with sepsis is much improved when they are diagnosed early and provided with proper therapy. Soluble triggering receptors expressed on myeloid cells (STREM-1), Interleukin-10 (IL-10), neuronal serum enolase (NSE), and so on are possible biomarkers for the diagnosis of sepsis based on the pathophysiology. Blood purification treatment to control the ...
Source: Mol Biol Cell - August 21, 2022 Category: Molecular Biology Authors: Yongping Zeng Dansen Wu Xiuming Zhuo JingShi Song Source Type: research
Effects of Continuous Blood Purification without Heparin on Strem-1, NSE, and IL-10 Levels In Patients With Sepsis
Cell Mol Biol (Noisy-le-grand). 2022 Apr 30;68(4):178-187. doi: 10.14715/cmb/2022.68.4.21.ABSTRACTOne of the most common causes of mortality and disability across the world is sepsis, a condition marked by an abnormal immunological reaction in the body. The prognosis of patients with sepsis is much improved when they are diagnosed early and provided with proper therapy. Soluble triggering receptors expressed on myeloid cells (STREM-1), Interleukin-10 (IL-10), neuronal serum enolase (NSE), and so on are possible biomarkers for the diagnosis of sepsis based on the pathophysiology. Blood purification treatment to control the ...
Source: Cellular and Molecular Biology - August 21, 2022 Category: Molecular Biology Authors: Yongping Zeng Dansen Wu Xiuming Zhuo JingShi Song Source Type: research
Effects of Continuous Blood Purification without Heparin on Strem-1, NSE, and IL-10 Levels In Patients With Sepsis
Cell Mol Biol (Noisy-le-grand). 2022 Apr 30;68(4):178-187. doi: 10.14715/cmb/2022.68.4.21.ABSTRACTOne of the most common causes of mortality and disability across the world is sepsis, a condition marked by an abnormal immunological reaction in the body. The prognosis of patients with sepsis is much improved when they are diagnosed early and provided with proper therapy. Soluble triggering receptors expressed on myeloid cells (STREM-1), Interleukin-10 (IL-10), neuronal serum enolase (NSE), and so on are possible biomarkers for the diagnosis of sepsis based on the pathophysiology. Blood purification treatment to control the ...
Source: Mol Biol Cell - August 21, 2022 Category: Molecular Biology Authors: Yongping Zeng Dansen Wu Xiuming Zhuo JingShi Song Source Type: research
Effects of Continuous Blood Purification without Heparin on Strem-1, NSE, and IL-10 Levels In Patients With Sepsis
Cell Mol Biol (Noisy-le-grand). 2022 Apr 30;68(4):178-187. doi: 10.14715/cmb/2022.68.4.21.ABSTRACTOne of the most common causes of mortality and disability across the world is sepsis, a condition marked by an abnormal immunological reaction in the body. The prognosis of patients with sepsis is much improved when they are diagnosed early and provided with proper therapy. Soluble triggering receptors expressed on myeloid cells (STREM-1), Interleukin-10 (IL-10), neuronal serum enolase (NSE), and so on are possible biomarkers for the diagnosis of sepsis based on the pathophysiology. Blood purification treatment to control the ...
Source: Cellular and Molecular Biology - August 21, 2022 Category: Molecular Biology Authors: Yongping Zeng Dansen Wu Xiuming Zhuo JingShi Song Source Type: research
