Ensuring hemodialysis adequacy by dialysis dose monitoring with UV spectroscopy analysis of spent dialyzate
CONCLUSION: Online monitoring of dialysis dose by Adimea® improves and maintains dialysis adequacy. Implementing online monitoring by Adimea into daily practice moves the quality of dialysis patient care a significant step forward.PMID:34812071 | DOI:10.1177/03913988211059841 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - November 23, 2021 Category: Transplant Surgery Authors: Li Zhang Wenhu Liu Chuanming Hao Yani He Ye Tao Shiren Sun Marten Jakob Daniele Marcelli Claudia Barth Xiangmei Chen Source Type: research

Ensuring hemodialysis adequacy by dialysis dose monitoring with UV spectroscopy analysis of spent dialyzate
CONCLUSION: Online monitoring of dialysis dose by Adimea® improves and maintains dialysis adequacy. Implementing online monitoring by Adimea into daily practice moves the quality of dialysis patient care a significant step forward.PMID:34812071 | DOI:10.1177/03913988211059841 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - November 23, 2021 Category: Transplant Surgery Authors: Li Zhang Wenhu Liu Chuanming Hao Yani He Ye Tao Shiren Sun Marten Jakob Daniele Marcelli Claudia Barth Xiangmei Chen Source Type: research

The influence of surface roughness on the damage of von Willebrand Factor under shear flow condition
In this study, the effect of surface roughness on VWF damage under flow condition was investigated. A roller pump circulation experimental platform with a roughness embedded sample chamber was constructed to provide blood shearing flow condition. VWF molecular weight analysis, VWF antigen (VWF-Ag) concentration assay, and VWF ristocetin cofactor activity (VWF-Rico) assay were performed on the sheared blood samples. These variables are the main functional indicators of VWF. It was found that the surface roughness induced VWF damage is mainly caused by the loss of HMW-VWF rather than reducing the total amount of VWF. The thr...
Source: The International Journal of Artificial Organs - November 5, 2021 Category: Transplant Surgery Authors: Xu Mei Bin Lu Min Zhong Yuxin Zhu Liudi Zhang Wanning Ge Source Type: research

The influence of surface roughness on the damage of von Willebrand Factor under shear flow condition
In this study, the effect of surface roughness on VWF damage under flow condition was investigated. A roller pump circulation experimental platform with a roughness embedded sample chamber was constructed to provide blood shearing flow condition. VWF molecular weight analysis, VWF antigen (VWF-Ag) concentration assay, and VWF ristocetin cofactor activity (VWF-Rico) assay were performed on the sheared blood samples. These variables are the main functional indicators of VWF. It was found that the surface roughness induced VWF damage is mainly caused by the loss of HMW-VWF rather than reducing the total amount of VWF. The thr...
Source: The International Journal of Artificial Organs - November 5, 2021 Category: Transplant Surgery Authors: Xu Mei Bin Lu Min Zhong Yuxin Zhu Liudi Zhang Wanning Ge Source Type: research

The influence of surface roughness on the damage of von Willebrand Factor under shear flow condition
In this study, the effect of surface roughness on VWF damage under flow condition was investigated. A roller pump circulation experimental platform with a roughness embedded sample chamber was constructed to provide blood shearing flow condition. VWF molecular weight analysis, VWF antigen (VWF-Ag) concentration assay, and VWF ristocetin cofactor activity (VWF-Rico) assay were performed on the sheared blood samples. These variables are the main functional indicators of VWF. It was found that the surface roughness induced VWF damage is mainly caused by the loss of HMW-VWF rather than reducing the total amount of VWF. The thr...
Source: The International Journal of Artificial Organs - November 5, 2021 Category: Transplant Surgery Authors: Xu Mei Bin Lu Min Zhong Yuxin Zhu Liudi Zhang Wanning Ge Source Type: research

The influence of surface roughness on the damage of von Willebrand Factor under shear flow condition
In this study, the effect of surface roughness on VWF damage under flow condition was investigated. A roller pump circulation experimental platform with a roughness embedded sample chamber was constructed to provide blood shearing flow condition. VWF molecular weight analysis, VWF antigen (VWF-Ag) concentration assay, and VWF ristocetin cofactor activity (VWF-Rico) assay were performed on the sheared blood samples. These variables are the main functional indicators of VWF. It was found that the surface roughness induced VWF damage is mainly caused by the loss of HMW-VWF rather than reducing the total amount of VWF. The thr...
Source: The International Journal of Artificial Organs - November 5, 2021 Category: Transplant Surgery Authors: Xu Mei Bin Lu Min Zhong Yuxin Zhu Liudi Zhang Wanning Ge Source Type: research

The influence of surface roughness on the damage of von Willebrand Factor under shear flow condition
In this study, the effect of surface roughness on VWF damage under flow condition was investigated. A roller pump circulation experimental platform with a roughness embedded sample chamber was constructed to provide blood shearing flow condition. VWF molecular weight analysis, VWF antigen (VWF-Ag) concentration assay, and VWF ristocetin cofactor activity (VWF-Rico) assay were performed on the sheared blood samples. These variables are the main functional indicators of VWF. It was found that the surface roughness induced VWF damage is mainly caused by the loss of HMW-VWF rather than reducing the total amount of VWF. The thr...
Source: The International Journal of Artificial Organs - November 5, 2021 Category: Transplant Surgery Authors: Xu Mei Bin Lu Min Zhong Yuxin Zhu Liudi Zhang Wanning Ge Source Type: research

The influence of surface roughness on the damage of von Willebrand Factor under shear flow condition
In this study, the effect of surface roughness on VWF damage under flow condition was investigated. A roller pump circulation experimental platform with a roughness embedded sample chamber was constructed to provide blood shearing flow condition. VWF molecular weight analysis, VWF antigen (VWF-Ag) concentration assay, and VWF ristocetin cofactor activity (VWF-Rico) assay were performed on the sheared blood samples. These variables are the main functional indicators of VWF. It was found that the surface roughness induced VWF damage is mainly caused by the loss of HMW-VWF rather than reducing the total amount of VWF. The thr...
Source: The International Journal of Artificial Organs - November 5, 2021 Category: Transplant Surgery Authors: Xu Mei Bin Lu Min Zhong Yuxin Zhu Liudi Zhang Wanning Ge Source Type: research

The influence of surface roughness on the damage of von Willebrand Factor under shear flow condition
In this study, the effect of surface roughness on VWF damage under flow condition was investigated. A roller pump circulation experimental platform with a roughness embedded sample chamber was constructed to provide blood shearing flow condition. VWF molecular weight analysis, VWF antigen (VWF-Ag) concentration assay, and VWF ristocetin cofactor activity (VWF-Rico) assay were performed on the sheared blood samples. These variables are the main functional indicators of VWF. It was found that the surface roughness induced VWF damage is mainly caused by the loss of HMW-VWF rather than reducing the total amount of VWF. The thr...
Source: The International Journal of Artificial Organs - November 5, 2021 Category: Transplant Surgery Authors: Xu Mei Bin Lu Min Zhong Yuxin Zhu Liudi Zhang Wanning Ge Source Type: research

The influence of surface roughness on the damage of von Willebrand Factor under shear flow condition
In this study, the effect of surface roughness on VWF damage under flow condition was investigated. A roller pump circulation experimental platform with a roughness embedded sample chamber was constructed to provide blood shearing flow condition. VWF molecular weight analysis, VWF antigen (VWF-Ag) concentration assay, and VWF ristocetin cofactor activity (VWF-Rico) assay were performed on the sheared blood samples. These variables are the main functional indicators of VWF. It was found that the surface roughness induced VWF damage is mainly caused by the loss of HMW-VWF rather than reducing the total amount of VWF. The thr...
Source: The International Journal of Artificial Organs - November 5, 2021 Category: Transplant Surgery Authors: Xu Mei Bin Lu Min Zhong Yuxin Zhu Liudi Zhang Wanning Ge Source Type: research

The influence of surface roughness on the damage of von Willebrand Factor under shear flow condition
In this study, the effect of surface roughness on VWF damage under flow condition was investigated. A roller pump circulation experimental platform with a roughness embedded sample chamber was constructed to provide blood shearing flow condition. VWF molecular weight analysis, VWF antigen (VWF-Ag) concentration assay, and VWF ristocetin cofactor activity (VWF-Rico) assay were performed on the sheared blood samples. These variables are the main functional indicators of VWF. It was found that the surface roughness induced VWF damage is mainly caused by the loss of HMW-VWF rather than reducing the total amount of VWF. The thr...
Source: The International Journal of Artificial Organs - November 5, 2021 Category: Transplant Surgery Authors: Xu Mei Bin Lu Min Zhong Yuxin Zhu Liudi Zhang Wanning Ge Source Type: research

The influence of surface roughness on the damage of von Willebrand Factor under shear flow condition
In this study, the effect of surface roughness on VWF damage under flow condition was investigated. A roller pump circulation experimental platform with a roughness embedded sample chamber was constructed to provide blood shearing flow condition. VWF molecular weight analysis, VWF antigen (VWF-Ag) concentration assay, and VWF ristocetin cofactor activity (VWF-Rico) assay were performed on the sheared blood samples. These variables are the main functional indicators of VWF. It was found that the surface roughness induced VWF damage is mainly caused by the loss of HMW-VWF rather than reducing the total amount of VWF. The thr...
Source: The International Journal of Artificial Organs - November 5, 2021 Category: Transplant Surgery Authors: Xu Mei Bin Lu Min Zhong Yuxin Zhu Liudi Zhang Wanning Ge Source Type: research

The influence of surface roughness on the damage of von Willebrand Factor under shear flow condition
In this study, the effect of surface roughness on VWF damage under flow condition was investigated. A roller pump circulation experimental platform with a roughness embedded sample chamber was constructed to provide blood shearing flow condition. VWF molecular weight analysis, VWF antigen (VWF-Ag) concentration assay, and VWF ristocetin cofactor activity (VWF-Rico) assay were performed on the sheared blood samples. These variables are the main functional indicators of VWF. It was found that the surface roughness induced VWF damage is mainly caused by the loss of HMW-VWF rather than reducing the total amount of VWF. The thr...
Source: The International Journal of Artificial Organs - November 5, 2021 Category: Transplant Surgery Authors: Xu Mei Bin Lu Min Zhong Yuxin Zhu Liudi Zhang Wanning Ge Source Type: research

The influence of surface roughness on the damage of von Willebrand Factor under shear flow condition
In this study, the effect of surface roughness on VWF damage under flow condition was investigated. A roller pump circulation experimental platform with a roughness embedded sample chamber was constructed to provide blood shearing flow condition. VWF molecular weight analysis, VWF antigen (VWF-Ag) concentration assay, and VWF ristocetin cofactor activity (VWF-Rico) assay were performed on the sheared blood samples. These variables are the main functional indicators of VWF. It was found that the surface roughness induced VWF damage is mainly caused by the loss of HMW-VWF rather than reducing the total amount of VWF. The thr...
Source: The International Journal of Artificial Organs - November 5, 2021 Category: Transplant Surgery Authors: Xu Mei Bin Lu Min Zhong Yuxin Zhu Liudi Zhang Wanning Ge Source Type: research

The influence of surface roughness on the damage of von Willebrand Factor under shear flow condition
In this study, the effect of surface roughness on VWF damage under flow condition was investigated. A roller pump circulation experimental platform with a roughness embedded sample chamber was constructed to provide blood shearing flow condition. VWF molecular weight analysis, VWF antigen (VWF-Ag) concentration assay, and VWF ristocetin cofactor activity (VWF-Rico) assay were performed on the sheared blood samples. These variables are the main functional indicators of VWF. It was found that the surface roughness induced VWF damage is mainly caused by the loss of HMW-VWF rather than reducing the total amount of VWF. The thr...
Source: The International Journal of Artificial Organs - November 5, 2021 Category: Transplant Surgery Authors: Xu Mei Bin Lu Min Zhong Yuxin Zhu Liudi Zhang Wanning Ge Source Type: research

The influence of surface roughness on the damage of von Willebrand Factor under shear flow condition
In this study, the effect of surface roughness on VWF damage under flow condition was investigated. A roller pump circulation experimental platform with a roughness embedded sample chamber was constructed to provide blood shearing flow condition. VWF molecular weight analysis, VWF antigen (VWF-Ag) concentration assay, and VWF ristocetin cofactor activity (VWF-Rico) assay were performed on the sheared blood samples. These variables are the main functional indicators of VWF. It was found that the surface roughness induced VWF damage is mainly caused by the loss of HMW-VWF rather than reducing the total amount of VWF. The thr...
Source: The International Journal of Artificial Organs - November 5, 2021 Category: Transplant Surgery Authors: Xu Mei Bin Lu Min Zhong Yuxin Zhu Liudi Zhang Wanning Ge Source Type: research

Comparison of household income in in-hospital outcomes after implantation of left ventricular assist device
Int J Artif Organs. 2021 Oct 31:3913988211056960. doi: 10.1177/03913988211056960. Online ahead of print.ABSTRACTINTRODUCTION: Due to the inability to keep up with the demand for heart transplantation, there is an increased utilization of left ventricular assist devices (LVAD). However, paucity of data exists regarding the association of household income with in-hospital outcomes after LVAD implantation.METHODS: Retrospective cohort study using the NIS to identify all patients ⩾18 years who underwent LVAD implantation from 2011 to 2017. Statistical analysis was performed comparing low household income (⩽50th percentile)...
Source: The International Journal of Artificial Organs - November 1, 2021 Category: Transplant Surgery Authors: Bertrand Ebner Morgan Karetnick Jelani Grant Louis Vincent Jennifer Maning Neal Olarte Odunayo Olorunfemi Colombo Rosario Sandra Chaparro Source Type: research

Comparison of household income in in-hospital outcomes after implantation of left ventricular assist device
Int J Artif Organs. 2021 Oct 31:3913988211056960. doi: 10.1177/03913988211056960. Online ahead of print.ABSTRACTINTRODUCTION: Due to the inability to keep up with the demand for heart transplantation, there is an increased utilization of left ventricular assist devices (LVAD). However, paucity of data exists regarding the association of household income with in-hospital outcomes after LVAD implantation.METHODS: Retrospective cohort study using the NIS to identify all patients ⩾18 years who underwent LVAD implantation from 2011 to 2017. Statistical analysis was performed comparing low household income (⩽50th percentile)...
Source: The International Journal of Artificial Organs - November 1, 2021 Category: Transplant Surgery Authors: Bertrand Ebner Morgan Karetnick Jelani Grant Louis Vincent Jennifer Maning Neal Olarte Odunayo Olorunfemi Colombo Rosario Sandra Chaparro Source Type: research

Comparison of household income in in-hospital outcomes after implantation of left ventricular assist device
Int J Artif Organs. 2021 Oct 31:3913988211056960. doi: 10.1177/03913988211056960. Online ahead of print.ABSTRACTINTRODUCTION: Due to the inability to keep up with the demand for heart transplantation, there is an increased utilization of left ventricular assist devices (LVAD). However, paucity of data exists regarding the association of household income with in-hospital outcomes after LVAD implantation.METHODS: Retrospective cohort study using the NIS to identify all patients ⩾18 years who underwent LVAD implantation from 2011 to 2017. Statistical analysis was performed comparing low household income (⩽50th percentile)...
Source: The International Journal of Artificial Organs - November 1, 2021 Category: Transplant Surgery Authors: Bertrand Ebner Morgan Karetnick Jelani Grant Louis Vincent Jennifer Maning Neal Olarte Odunayo Olorunfemi Colombo Rosario Sandra Chaparro Source Type: research

Comparison of household income in in-hospital outcomes after implantation of left ventricular assist device
Int J Artif Organs. 2021 Oct 31:3913988211056960. doi: 10.1177/03913988211056960. Online ahead of print.ABSTRACTINTRODUCTION: Due to the inability to keep up with the demand for heart transplantation, there is an increased utilization of left ventricular assist devices (LVAD). However, paucity of data exists regarding the association of household income with in-hospital outcomes after LVAD implantation.METHODS: Retrospective cohort study using the NIS to identify all patients ⩾18 years who underwent LVAD implantation from 2011 to 2017. Statistical analysis was performed comparing low household income (⩽50th percentile)...
Source: The International Journal of Artificial Organs - November 1, 2021 Category: Transplant Surgery Authors: Bertrand Ebner Morgan Karetnick Jelani Grant Louis Vincent Jennifer Maning Neal Olarte Odunayo Olorunfemi Colombo Rosario Sandra Chaparro Source Type: research

Effects of the atrium on intraventricular flow patterns during mechanical circulatory support
In this study, the influence of the left atrium (LA) on the intra-ventricular flow was investigated via Computational Fluid Dynamics (CFD) simulations. Ventricular flow was simulated by a combined Eulerian (carrier flow)/Lagrangian (particles) approach taking into account either the LA or a cylindrical inflow section to mimic a fully support condition. The flow deviation at the mitral valve, the blood low-velocity volume as well as the residence time and shear stress history of the particles were calculated. Inclusion of the LA deflects the flow at the mitral valve by 25°, resulting in an asymmetric flow jet entering t...
Source: The International Journal of Artificial Organs - October 30, 2021 Category: Transplant Surgery Authors: Mojgan Ghodrati Thomas Schl öglhofer Alexander Maurer Thananya Khienwad Daniel Zimpfer Dietrich Beitzke Francesco Zonta Francesco Moscato Heinrich Schima Philipp Aigner Source Type: research

Effects of the atrium on intraventricular flow patterns during mechanical circulatory support
In this study, the influence of the left atrium (LA) on the intra-ventricular flow was investigated via Computational Fluid Dynamics (CFD) simulations. Ventricular flow was simulated by a combined Eulerian (carrier flow)/Lagrangian (particles) approach taking into account either the LA or a cylindrical inflow section to mimic a fully support condition. The flow deviation at the mitral valve, the blood low-velocity volume as well as the residence time and shear stress history of the particles were calculated. Inclusion of the LA deflects the flow at the mitral valve by 25°, resulting in an asymmetric flow jet entering t...
Source: The International Journal of Artificial Organs - October 30, 2021 Category: Transplant Surgery Authors: Mojgan Ghodrati Thomas Schl öglhofer Alexander Maurer Thananya Khienwad Daniel Zimpfer Dietrich Beitzke Francesco Zonta Francesco Moscato Heinrich Schima Philipp Aigner Source Type: research

MELD score is predictive of 90-day mortality after veno-arterial extracorporeal membrane oxygenation support
This study assessed the prognostic impact of MELD in patients with cardiogenic shock undergoing VA ECMO via a single-center retrospective review from January 2014 to March 2020. MELD, MELD-XI, and MELD-Na scores were calculated using laboratory values collected within 48 h of VA ECMO initiation. Multivariate Cox regression analyses determined the association between MELD scores and the primary outcome of 90-day mortality. Receiver operating characteristics (ROC) were used to estimate the discriminatory power for MELD in comparison with previously validated SAVE score.RESULTS: Of the 194 patients, median MELD was 20.1 (13.7...
Source: The International Journal of Artificial Organs - October 27, 2021 Category: Transplant Surgery Authors: Mohamad Karnib Rebecca Haraf Nour Tashtish Erica Zanath Tarek Elshazly Raul Angel Garcia Scott Billings Michael Fetros Allison Bradigan Michael Zacharias Yasir Abu-Omar Yakov Elgudin Marc Pelletier Sadeer Al-Kindi Francis Lytle Chantal ElAmm Source Type: research

CytoSorb purification in critically ill SARS-CoV-2 patients
CONCLUSIONS: CytoSorb treatment was effective in improving several laboratory parameters and inflammation in our experience and no treatment-related adverse effects were recorded. In the light of the unique pathophysiology of SARS-CoV-2 infection, CytoSorb treatment is extremely promising, since it might both reduce inflammation and activation of coagulation.PMID:34702109 | DOI:10.1177/03913988211052572 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - October 27, 2021 Category: Transplant Surgery Authors: Marina Pieri Evgeny Fominskiy Pasquale Nardelli Matteo A Bonizzoni Anna M Scandroglio Source Type: research

MELD score is predictive of 90-day mortality after veno-arterial extracorporeal membrane oxygenation support
This study assessed the prognostic impact of MELD in patients with cardiogenic shock undergoing VA ECMO via a single-center retrospective review from January 2014 to March 2020. MELD, MELD-XI, and MELD-Na scores were calculated using laboratory values collected within 48 h of VA ECMO initiation. Multivariate Cox regression analyses determined the association between MELD scores and the primary outcome of 90-day mortality. Receiver operating characteristics (ROC) were used to estimate the discriminatory power for MELD in comparison with previously validated SAVE score.RESULTS: Of the 194 patients, median MELD was 20.1 (13.7...
Source: The International Journal of Artificial Organs - October 27, 2021 Category: Transplant Surgery Authors: Mohamad Karnib Rebecca Haraf Nour Tashtish Erica Zanath Tarek Elshazly Raul Angel Garcia Scott Billings Michael Fetros Allison Bradigan Michael Zacharias Yasir Abu-Omar Yakov Elgudin Marc Pelletier Sadeer Al-Kindi Francis Lytle Chantal ElAmm Source Type: research

CytoSorb purification in critically ill SARS-CoV-2 patients
CONCLUSIONS: CytoSorb treatment was effective in improving several laboratory parameters and inflammation in our experience and no treatment-related adverse effects were recorded. In the light of the unique pathophysiology of SARS-CoV-2 infection, CytoSorb treatment is extremely promising, since it might both reduce inflammation and activation of coagulation.PMID:34702109 | DOI:10.1177/03913988211052572 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - October 27, 2021 Category: Transplant Surgery Authors: Marina Pieri Evgeny Fominskiy Pasquale Nardelli Matteo A Bonizzoni Anna M Scandroglio Source Type: research

MELD score is predictive of 90-day mortality after veno-arterial extracorporeal membrane oxygenation support
This study assessed the prognostic impact of MELD in patients with cardiogenic shock undergoing VA ECMO via a single-center retrospective review from January 2014 to March 2020. MELD, MELD-XI, and MELD-Na scores were calculated using laboratory values collected within 48 h of VA ECMO initiation. Multivariate Cox regression analyses determined the association between MELD scores and the primary outcome of 90-day mortality. Receiver operating characteristics (ROC) were used to estimate the discriminatory power for MELD in comparison with previously validated SAVE score.RESULTS: Of the 194 patients, median MELD was 20.1 (13.7...
Source: The International Journal of Artificial Organs - October 27, 2021 Category: Transplant Surgery Authors: Mohamad Karnib Rebecca Haraf Nour Tashtish Erica Zanath Tarek Elshazly Raul Angel Garcia Scott Billings Michael Fetros Allison Bradigan Michael Zacharias Yasir Abu-Omar Yakov Elgudin Marc Pelletier Sadeer Al-Kindi Francis Lytle Chantal ElAmm Source Type: research

CytoSorb purification in critically ill SARS-CoV-2 patients
CONCLUSIONS: CytoSorb treatment was effective in improving several laboratory parameters and inflammation in our experience and no treatment-related adverse effects were recorded. In the light of the unique pathophysiology of SARS-CoV-2 infection, CytoSorb treatment is extremely promising, since it might both reduce inflammation and activation of coagulation.PMID:34702109 | DOI:10.1177/03913988211052572 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - October 27, 2021 Category: Transplant Surgery Authors: Marina Pieri Evgeny Fominskiy Pasquale Nardelli Matteo A Bonizzoni Anna M Scandroglio Source Type: research

Rescue extracorporeal life support as a bridge to durable left ventricular assist device
CONCLUSION: The concept of bridging patients presenting in end-stage heart failure and cardiogenic shock with ECLS prior to durable LVAD implantation is a feasible method to ensure acceptable survival rates and significant recovery of the end-organ function.PMID:34674570 | DOI:10.1177/03913988211053874 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - October 22, 2021 Category: Transplant Surgery Authors: Alina Zubarevich Konstantin Zhigalov Marcin Szczechowicz Arian Arjomandi Rad Robert Vardanyan Saeed Torabi Maria Papathanasiou Peter Luedike Achim Koch Nikolaus Pizanis Markus Kamler Bastian Schmack Arjang Ruhparwar Alexander Weymann Source Type: research

Rescue extracorporeal life support as a bridge to durable left ventricular assist device
CONCLUSION: The concept of bridging patients presenting in end-stage heart failure and cardiogenic shock with ECLS prior to durable LVAD implantation is a feasible method to ensure acceptable survival rates and significant recovery of the end-organ function.PMID:34674570 | DOI:10.1177/03913988211053874 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - October 22, 2021 Category: Transplant Surgery Authors: Alina Zubarevich Konstantin Zhigalov Marcin Szczechowicz Arian Arjomandi Rad Robert Vardanyan Saeed Torabi Maria Papathanasiou Peter Luedike Achim Koch Nikolaus Pizanis Markus Kamler Bastian Schmack Arjang Ruhparwar Alexander Weymann Source Type: research

Rescue extracorporeal life support as a bridge to durable left ventricular assist device
CONCLUSION: The concept of bridging patients presenting in end-stage heart failure and cardiogenic shock with ECLS prior to durable LVAD implantation is a feasible method to ensure acceptable survival rates and significant recovery of the end-organ function.PMID:34674570 | DOI:10.1177/03913988211053874 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - October 22, 2021 Category: Transplant Surgery Authors: Alina Zubarevich Konstantin Zhigalov Marcin Szczechowicz Arian Arjomandi Rad Robert Vardanyan Saeed Torabi Maria Papathanasiou Peter Luedike Achim Koch Nikolaus Pizanis Markus Kamler Bastian Schmack Arjang Ruhparwar Alexander Weymann Source Type: research

In vitro hemocompatibility investigation for the development of low-flow centrifugal blood pumps with less platelet clogging
Int J Artif Organs. 2021 Oct 18:3913988211052570. doi: 10.1177/03913988211052570. Online ahead of print.ABSTRACTLow-flow blood pumps rated under 1 L/min are emerging for new medical applications, such as hemofiltration in acute use. In those pumps, platelet adhesion and aggregation have to be carefully considered because of clogging risk in the filter part. To find an acceptable hemocompatibility that can be applied to low-flow centrifugal blood pump design, the platelet aggregation index, clogging on a micromesh filter, and the hemolysis index were investigated using a low-flow blood pump designed for hemofiltration use. ...
Source: The International Journal of Artificial Organs - October 18, 2021 Category: Transplant Surgery Authors: Akiko Oota-Ishigaki Takashi Yamane Daisuke Sakota Ryo Kosaka Osamu Maruyama Masahiro Nishida Source Type: research

In vitro hemocompatibility investigation for the development of low-flow centrifugal blood pumps with less platelet clogging
Int J Artif Organs. 2021 Oct 18:3913988211052570. doi: 10.1177/03913988211052570. Online ahead of print.ABSTRACTLow-flow blood pumps rated under 1 L/min are emerging for new medical applications, such as hemofiltration in acute use. In those pumps, platelet adhesion and aggregation have to be carefully considered because of clogging risk in the filter part. To find an acceptable hemocompatibility that can be applied to low-flow centrifugal blood pump design, the platelet aggregation index, clogging on a micromesh filter, and the hemolysis index were investigated using a low-flow blood pump designed for hemofiltration use. ...
Source: The International Journal of Artificial Organs - October 18, 2021 Category: Transplant Surgery Authors: Akiko Oota-Ishigaki Takashi Yamane Daisuke Sakota Ryo Kosaka Osamu Maruyama Masahiro Nishida Source Type: research

In vitro hemocompatibility investigation for the development of low-flow centrifugal blood pumps with less platelet clogging
Int J Artif Organs. 2021 Oct 18:3913988211052570. doi: 10.1177/03913988211052570. Online ahead of print.ABSTRACTLow-flow blood pumps rated under 1 L/min are emerging for new medical applications, such as hemofiltration in acute use. In those pumps, platelet adhesion and aggregation have to be carefully considered because of clogging risk in the filter part. To find an acceptable hemocompatibility that can be applied to low-flow centrifugal blood pump design, the platelet aggregation index, clogging on a micromesh filter, and the hemolysis index were investigated using a low-flow blood pump designed for hemofiltration use. ...
Source: The International Journal of Artificial Organs - October 18, 2021 Category: Transplant Surgery Authors: Akiko Oota-Ishigaki Takashi Yamane Daisuke Sakota Ryo Kosaka Osamu Maruyama Masahiro Nishida Source Type: research

In vitro hemocompatibility investigation for the development of low-flow centrifugal blood pumps with less platelet clogging
Int J Artif Organs. 2021 Oct 18:3913988211052570. doi: 10.1177/03913988211052570. Online ahead of print.ABSTRACTLow-flow blood pumps rated under 1 L/min are emerging for new medical applications, such as hemofiltration in acute use. In those pumps, platelet adhesion and aggregation have to be carefully considered because of clogging risk in the filter part. To find an acceptable hemocompatibility that can be applied to low-flow centrifugal blood pump design, the platelet aggregation index, clogging on a micromesh filter, and the hemolysis index were investigated using a low-flow blood pump designed for hemofiltration use. ...
Source: The International Journal of Artificial Organs - October 18, 2021 Category: Transplant Surgery Authors: Akiko Oota-Ishigaki Takashi Yamane Daisuke Sakota Ryo Kosaka Osamu Maruyama Masahiro Nishida Source Type: research

In vitro hemocompatibility investigation for the development of low-flow centrifugal blood pumps with less platelet clogging
Int J Artif Organs. 2021 Oct 18:3913988211052570. doi: 10.1177/03913988211052570. Online ahead of print.ABSTRACTLow-flow blood pumps rated under 1 L/min are emerging for new medical applications, such as hemofiltration in acute use. In those pumps, platelet adhesion and aggregation have to be carefully considered because of clogging risk in the filter part. To find an acceptable hemocompatibility that can be applied to low-flow centrifugal blood pump design, the platelet aggregation index, clogging on a micromesh filter, and the hemolysis index were investigated using a low-flow blood pump designed for hemofiltration use. ...
Source: The International Journal of Artificial Organs - October 18, 2021 Category: Transplant Surgery Authors: Akiko Oota-Ishigaki Takashi Yamane Daisuke Sakota Ryo Kosaka Osamu Maruyama Masahiro Nishida Source Type: research

Lung ultrasound and the role of lung aeration score in patients with acute respiratory distress syndrome on extracorporeal membrane oxygenation
CONCLUSIONS: LUS correlated with findings on CT and CXR for quantifying lung aeration and the clinical presentation of patients. LUS also picked up more pleural effusions and pneumothorax than CXR. Together with traditional imaging techniques, the routine use of LUS should be considered for this patient group.PMID:34643145 | DOI:10.1177/03913988211051395 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - October 13, 2021 Category: Transplant Surgery Authors: Stefanie Curry Aileen Tan Luna Gargani Oriana Ng Andrew Roscoe Kiran Salaunkey Bobby Agrawal Alain Vuylsteke Jo-Anne Fowles Antonio Rubino Source Type: research

Donor variability alters differentiation and mechanical cohesion of tissue-engineered constructs with human endothelial/MSC co-culture
Int J Artif Organs. 2021 Oct 13:3913988211051758. doi: 10.1177/03913988211051758. Online ahead of print.ABSTRACTTo move towards clinical applications, tissue engineering (TE) should be validated with human primary cells and offer easy connection to the native vascularisation. Based on a sheet-like bone substitute developed previously, we investigated a mesenchymal stem cells/endothelial cells (MSCs/ECs) coculture to enhance pre-vascularisation. Using MSCs from six independent donors whose differentiation potential was assessed towards two lineages, we focused on donor variability and cell crosstalk regarding bone different...
Source: The International Journal of Artificial Organs - October 13, 2021 Category: Transplant Surgery Authors: Timoth ée Baudequin Marie Naudot S ébastien Dupont Sylvie Testelin Bernard Devauchelle Fahmi Bedoui Jean-Pierre Marolleau C écile Legallais Source Type: research

Lung ultrasound and the role of lung aeration score in patients with acute respiratory distress syndrome on extracorporeal membrane oxygenation
CONCLUSIONS: LUS correlated with findings on CT and CXR for quantifying lung aeration and the clinical presentation of patients. LUS also picked up more pleural effusions and pneumothorax than CXR. Together with traditional imaging techniques, the routine use of LUS should be considered for this patient group.PMID:34643145 | DOI:10.1177/03913988211051395 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - October 13, 2021 Category: Transplant Surgery Authors: Stefanie Curry Aileen Tan Luna Gargani Oriana Ng Andrew Roscoe Kiran Salaunkey Bobby Agrawal Alain Vuylsteke Jo-Anne Fowles Antonio Rubino Source Type: research

Donor variability alters differentiation and mechanical cohesion of tissue-engineered constructs with human endothelial/MSC co-culture
Int J Artif Organs. 2021 Oct 13:3913988211051758. doi: 10.1177/03913988211051758. Online ahead of print.ABSTRACTTo move towards clinical applications, tissue engineering (TE) should be validated with human primary cells and offer easy connection to the native vascularisation. Based on a sheet-like bone substitute developed previously, we investigated a mesenchymal stem cells/endothelial cells (MSCs/ECs) coculture to enhance pre-vascularisation. Using MSCs from six independent donors whose differentiation potential was assessed towards two lineages, we focused on donor variability and cell crosstalk regarding bone different...
Source: The International Journal of Artificial Organs - October 13, 2021 Category: Transplant Surgery Authors: Timoth ée Baudequin Marie Naudot S ébastien Dupont Sylvie Testelin Bernard Devauchelle Fahmi Bedoui Jean-Pierre Marolleau C écile Legallais Source Type: research

Lung ultrasound and the role of lung aeration score in patients with acute respiratory distress syndrome on extracorporeal membrane oxygenation
CONCLUSIONS: LUS correlated with findings on CT and CXR for quantifying lung aeration and the clinical presentation of patients. LUS also picked up more pleural effusions and pneumothorax than CXR. Together with traditional imaging techniques, the routine use of LUS should be considered for this patient group.PMID:34643145 | DOI:10.1177/03913988211051395 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - October 13, 2021 Category: Transplant Surgery Authors: Stefanie Curry Aileen Tan Luna Gargani Oriana Ng Andrew Roscoe Kiran Salaunkey Bobby Agrawal Alain Vuylsteke Jo-Anne Fowles Antonio Rubino Source Type: research

Donor variability alters differentiation and mechanical cohesion of tissue-engineered constructs with human endothelial/MSC co-culture
Int J Artif Organs. 2021 Oct 13:3913988211051758. doi: 10.1177/03913988211051758. Online ahead of print.ABSTRACTTo move towards clinical applications, tissue engineering (TE) should be validated with human primary cells and offer easy connection to the native vascularisation. Based on a sheet-like bone substitute developed previously, we investigated a mesenchymal stem cells/endothelial cells (MSCs/ECs) coculture to enhance pre-vascularisation. Using MSCs from six independent donors whose differentiation potential was assessed towards two lineages, we focused on donor variability and cell crosstalk regarding bone different...
Source: The International Journal of Artificial Organs - October 13, 2021 Category: Transplant Surgery Authors: Timoth ée Baudequin Marie Naudot S ébastien Dupont Sylvie Testelin Bernard Devauchelle Fahmi Bedoui Jean-Pierre Marolleau C écile Legallais Source Type: research

Lung ultrasound and the role of lung aeration score in patients with acute respiratory distress syndrome on extracorporeal membrane oxygenation
CONCLUSIONS: LUS correlated with findings on CT and CXR for quantifying lung aeration and the clinical presentation of patients. LUS also picked up more pleural effusions and pneumothorax than CXR. Together with traditional imaging techniques, the routine use of LUS should be considered for this patient group.PMID:34643145 | DOI:10.1177/03913988211051395 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - October 13, 2021 Category: Transplant Surgery Authors: Stefanie Curry Aileen Tan Luna Gargani Oriana Ng Andrew Roscoe Kiran Salaunkey Bobby Agrawal Alain Vuylsteke Jo-Anne Fowles Antonio Rubino Source Type: research

Donor variability alters differentiation and mechanical cohesion of tissue-engineered constructs with human endothelial/MSC co-culture
Int J Artif Organs. 2021 Oct 13:3913988211051758. doi: 10.1177/03913988211051758. Online ahead of print.ABSTRACTTo move towards clinical applications, tissue engineering (TE) should be validated with human primary cells and offer easy connection to the native vascularisation. Based on a sheet-like bone substitute developed previously, we investigated a mesenchymal stem cells/endothelial cells (MSCs/ECs) coculture to enhance pre-vascularisation. Using MSCs from six independent donors whose differentiation potential was assessed towards two lineages, we focused on donor variability and cell crosstalk regarding bone different...
Source: The International Journal of Artificial Organs - October 13, 2021 Category: Transplant Surgery Authors: Timoth ée Baudequin Marie Naudot S ébastien Dupont Sylvie Testelin Bernard Devauchelle Fahmi Bedoui Jean-Pierre Marolleau C écile Legallais Source Type: research

Lung ultrasound and the role of lung aeration score in patients with acute respiratory distress syndrome on extracorporeal membrane oxygenation
CONCLUSIONS: LUS correlated with findings on CT and CXR for quantifying lung aeration and the clinical presentation of patients. LUS also picked up more pleural effusions and pneumothorax than CXR. Together with traditional imaging techniques, the routine use of LUS should be considered for this patient group.PMID:34643145 | DOI:10.1177/03913988211051395 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - October 13, 2021 Category: Transplant Surgery Authors: Stefanie Curry Aileen Tan Luna Gargani Oriana Ng Andrew Roscoe Kiran Salaunkey Bobby Agrawal Alain Vuylsteke Jo-Anne Fowles Antonio Rubino Source Type: research

Donor variability alters differentiation and mechanical cohesion of tissue-engineered constructs with human endothelial/MSC co-culture
Int J Artif Organs. 2021 Oct 13:3913988211051758. doi: 10.1177/03913988211051758. Online ahead of print.ABSTRACTTo move towards clinical applications, tissue engineering (TE) should be validated with human primary cells and offer easy connection to the native vascularisation. Based on a sheet-like bone substitute developed previously, we investigated a mesenchymal stem cells/endothelial cells (MSCs/ECs) coculture to enhance pre-vascularisation. Using MSCs from six independent donors whose differentiation potential was assessed towards two lineages, we focused on donor variability and cell crosstalk regarding bone different...
Source: The International Journal of Artificial Organs - October 13, 2021 Category: Transplant Surgery Authors: Timoth ée Baudequin Marie Naudot S ébastien Dupont Sylvie Testelin Bernard Devauchelle Fahmi Bedoui Jean-Pierre Marolleau C écile Legallais Source Type: research

Clinical outcomes of severe COVID-19 patients receiving early VV-ECMO and the impact of pre-ECMO ventilator use
We describe clinical outcomes and survival rates in 52 COVID-19 patients with ARDS treated with early VV-ECMO at a large, high-volume center ECMO program. Outcomes included arterial blood gases, respiratory parameters, inflammatory markers, adverse events, and survival rates. Patients' mean age was 47.8 ± 12.1 years, 33% were female, and 75% were Hispanic. At the end of study period, 56% (n = 29) of the patients survived and were discharged and 44% (n = 23) of the patients expired. Survival rate was 75.0% (9 out of 12) in patients placed on ECMO prior to mechanical ventilation. Longer duration on mechanical ventilat...
Source: The International Journal of Artificial Organs - October 7, 2021 Category: Transplant Surgery Authors: Chandra Kunavarapu Samrat Yeramaneni Jairo Melo Rachel K Sterling Lindsey C Huskey Lindsay Sears Charles Burch Steve M Rodriguez Phillip J Habib Fernando Triana Jeffrey DellaVolpe Source Type: research

Clinical outcomes of severe COVID-19 patients receiving early VV-ECMO and the impact of pre-ECMO ventilator use
We describe clinical outcomes and survival rates in 52 COVID-19 patients with ARDS treated with early VV-ECMO at a large, high-volume center ECMO program. Outcomes included arterial blood gases, respiratory parameters, inflammatory markers, adverse events, and survival rates. Patients' mean age was 47.8 ± 12.1 years, 33% were female, and 75% were Hispanic. At the end of study period, 56% (n = 29) of the patients survived and were discharged and 44% (n = 23) of the patients expired. Survival rate was 75.0% (9 out of 12) in patients placed on ECMO prior to mechanical ventilation. Longer duration on mechanical ventilat...
Source: The International Journal of Artificial Organs - October 7, 2021 Category: Transplant Surgery Authors: Chandra Kunavarapu Samrat Yeramaneni Jairo Melo Rachel K Sterling Lindsey C Huskey Lindsay Sears Charles Burch Steve M Rodriguez Phillip J Habib Fernando Triana Jeffrey DellaVolpe Source Type: research

Clinical outcomes of severe COVID-19 patients receiving early VV-ECMO and the impact of pre-ECMO ventilator use
We describe clinical outcomes and survival rates in 52 COVID-19 patients with ARDS treated with early VV-ECMO at a large, high-volume center ECMO program. Outcomes included arterial blood gases, respiratory parameters, inflammatory markers, adverse events, and survival rates. Patients' mean age was 47.8 ± 12.1 years, 33% were female, and 75% were Hispanic. At the end of study period, 56% (n = 29) of the patients survived and were discharged and 44% (n = 23) of the patients expired. Survival rate was 75.0% (9 out of 12) in patients placed on ECMO prior to mechanical ventilation. Longer duration on mechanical ventilat...
Source: The International Journal of Artificial Organs - October 7, 2021 Category: Transplant Surgery Authors: Chandra Kunavarapu Samrat Yeramaneni Jairo Melo Rachel K Sterling Lindsey C Huskey Lindsay Sears Charles Burch Steve M Rodriguez Phillip J Habib Fernando Triana Jeffrey DellaVolpe Source Type: research

Clinical outcomes of severe COVID-19 patients receiving early VV-ECMO and the impact of pre-ECMO ventilator use
We describe clinical outcomes and survival rates in 52 COVID-19 patients with ARDS treated with early VV-ECMO at a large, high-volume center ECMO program. Outcomes included arterial blood gases, respiratory parameters, inflammatory markers, adverse events, and survival rates. Patients' mean age was 47.8 ± 12.1 years, 33% were female, and 75% were Hispanic. At the end of study period, 56% (n = 29) of the patients survived and were discharged and 44% (n = 23) of the patients expired. Survival rate was 75.0% (9 out of 12) in patients placed on ECMO prior to mechanical ventilation. Longer duration on mechanical ventilat...
Source: The International Journal of Artificial Organs - October 7, 2021 Category: Transplant Surgery Authors: Chandra Kunavarapu Samrat Yeramaneni Jairo Melo Rachel K Sterling Lindsey C Huskey Lindsay Sears Charles Burch Steve M Rodriguez Phillip J Habib Fernando Triana Jeffrey DellaVolpe Source Type: research