High prevalence of hepatitis E among regular hemodialysis patients in South of Iran
CONCLUSION: This study reports the highest seroprevalence of HEV among hemodialysis patients in Iran. Inapparent HEV infection in the dialysis setting calls for regular screening of hemodialysis patients regardless of the hemodialysis duration, clinical symptoms, and liver function parameters.PMID:34308705 | DOI:10.1177/03913988211027177 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - July 26, 2021 Category: Transplant Surgery Authors: Mahbube Ouji Reza Taherkhani Fatemeh Farshadpour Source Type: research

High prevalence of hepatitis E among regular hemodialysis patients in South of Iran
CONCLUSION: This study reports the highest seroprevalence of HEV among hemodialysis patients in Iran. Inapparent HEV infection in the dialysis setting calls for regular screening of hemodialysis patients regardless of the hemodialysis duration, clinical symptoms, and liver function parameters.PMID:34308705 | DOI:10.1177/03913988211027177 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - July 26, 2021 Category: Transplant Surgery Authors: Mahbube Ouji Reza Taherkhani Fatemeh Farshadpour Source Type: research

High prevalence of hepatitis E among regular hemodialysis patients in South of Iran
CONCLUSION: This study reports the highest seroprevalence of HEV among hemodialysis patients in Iran. Inapparent HEV infection in the dialysis setting calls for regular screening of hemodialysis patients regardless of the hemodialysis duration, clinical symptoms, and liver function parameters.PMID:34308705 | DOI:10.1177/03913988211027177 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - July 26, 2021 Category: Transplant Surgery Authors: Mahbube Ouji Reza Taherkhani Fatemeh Farshadpour Source Type: research

Adjuvant hemoadsorption therapy in patients with severe COVID-19 and related organ failure requiring CRRT or ECMO therapy: A case series
CONCLUSIONS: In this case series of SARS-CoV-2 infected patients admitted to the intensive care unit with ARDS, we report effective interleukin (IL)-6 removal, reduced norepinephrine requirement, and improved lung function while receiving adjuvant, extracorporeal hemoadsorption therapy in the context of a multimodal treatment approach. The presented protocol for CytoSorb initiation may be a good foundation for the development of further prospective studies in the field and may eventually also be applied to other forms of hyperinflammatory ARDS.PMID:34256643 | DOI:10.1177/03913988211030517 (Source: The International Journal...
Source: The International Journal of Artificial Organs - July 14, 2021 Category: Transplant Surgery Authors: Florian Wunderlich-Sperl Sebastian Kautzky Christian Pickem Christoph H örmann Source Type: research

Adjuvant hemoadsorption therapy in patients with severe COVID-19 and related organ failure requiring CRRT or ECMO therapy: A case series
CONCLUSIONS: In this case series of SARS-CoV-2 infected patients admitted to the intensive care unit with ARDS, we report effective interleukin (IL)-6 removal, reduced norepinephrine requirement, and improved lung function while receiving adjuvant, extracorporeal hemoadsorption therapy in the context of a multimodal treatment approach. The presented protocol for CytoSorb initiation may be a good foundation for the development of further prospective studies in the field and may eventually also be applied to other forms of hyperinflammatory ARDS.PMID:34256643 | DOI:10.1177/03913988211030517 (Source: The International Journal...
Source: The International Journal of Artificial Organs - July 14, 2021 Category: Transplant Surgery Authors: Florian Wunderlich-Sperl Sebastian Kautzky Christian Pickem Christoph H örmann Source Type: research

Adjuvant hemoadsorption therapy in patients with severe COVID-19 and related organ failure requiring CRRT or ECMO therapy: A case series
CONCLUSIONS: In this case series of SARS-CoV-2 infected patients admitted to the intensive care unit with ARDS, we report effective interleukin (IL)-6 removal, reduced norepinephrine requirement, and improved lung function while receiving adjuvant, extracorporeal hemoadsorption therapy in the context of a multimodal treatment approach. The presented protocol for CytoSorb initiation may be a good foundation for the development of further prospective studies in the field and may eventually also be applied to other forms of hyperinflammatory ARDS.PMID:34256643 | DOI:10.1177/03913988211030517 (Source: The International Journal...
Source: The International Journal of Artificial Organs - July 14, 2021 Category: Transplant Surgery Authors: Florian Wunderlich-Sperl Sebastian Kautzky Christian Pickem Christoph H örmann Source Type: research

Adjuvant hemoadsorption therapy in patients with severe COVID-19 and related organ failure requiring CRRT or ECMO therapy: A case series
CONCLUSIONS: In this case series of SARS-CoV-2 infected patients admitted to the intensive care unit with ARDS, we report effective interleukin (IL)-6 removal, reduced norepinephrine requirement, and improved lung function while receiving adjuvant, extracorporeal hemoadsorption therapy in the context of a multimodal treatment approach. The presented protocol for CytoSorb initiation may be a good foundation for the development of further prospective studies in the field and may eventually also be applied to other forms of hyperinflammatory ARDS.PMID:34256643 | DOI:10.1177/03913988211030517 (Source: The International Journal...
Source: The International Journal of Artificial Organs - July 14, 2021 Category: Transplant Surgery Authors: Florian Wunderlich-Sperl Sebastian Kautzky Christian Pickem Christoph H örmann Source Type: research

Adjuvant hemoadsorption therapy in patients with severe COVID-19 and related organ failure requiring CRRT or ECMO therapy: A case series
CONCLUSIONS: In this case series of SARS-CoV-2 infected patients admitted to the intensive care unit with ARDS, we report effective interleukin (IL)-6 removal, reduced norepinephrine requirement, and improved lung function while receiving adjuvant, extracorporeal hemoadsorption therapy in the context of a multimodal treatment approach. The presented protocol for CytoSorb initiation may be a good foundation for the development of further prospective studies in the field and may eventually also be applied to other forms of hyperinflammatory ARDS.PMID:34256643 | DOI:10.1177/03913988211030517 (Source: The International Journal...
Source: The International Journal of Artificial Organs - July 14, 2021 Category: Transplant Surgery Authors: Florian Wunderlich-Sperl Sebastian Kautzky Christian Pickem Christoph H örmann Source Type: research

Adjuvant hemoadsorption therapy in patients with severe COVID-19 and related organ failure requiring CRRT or ECMO therapy: A case series
CONCLUSIONS: In this case series of SARS-CoV-2 infected patients admitted to the intensive care unit with ARDS, we report effective interleukin (IL)-6 removal, reduced norepinephrine requirement, and improved lung function while receiving adjuvant, extracorporeal hemoadsorption therapy in the context of a multimodal treatment approach. The presented protocol for CytoSorb initiation may be a good foundation for the development of further prospective studies in the field and may eventually also be applied to other forms of hyperinflammatory ARDS.PMID:34256643 | DOI:10.1177/03913988211030517 (Source: The International Journal...
Source: The International Journal of Artificial Organs - July 14, 2021 Category: Transplant Surgery Authors: Florian Wunderlich-Sperl Sebastian Kautzky Christian Pickem Christoph H örmann Source Type: research

Adjuvant hemoadsorption therapy in patients with severe COVID-19 and related organ failure requiring CRRT or ECMO therapy: A case series
CONCLUSIONS: In this case series of SARS-CoV-2 infected patients admitted to the intensive care unit with ARDS, we report effective interleukin (IL)-6 removal, reduced norepinephrine requirement, and improved lung function while receiving adjuvant, extracorporeal hemoadsorption therapy in the context of a multimodal treatment approach. The presented protocol for CytoSorb initiation may be a good foundation for the development of further prospective studies in the field and may eventually also be applied to other forms of hyperinflammatory ARDS.PMID:34256643 | DOI:10.1177/03913988211030517 (Source: The International Journal...
Source: The International Journal of Artificial Organs - July 14, 2021 Category: Transplant Surgery Authors: Florian Wunderlich-Sperl Sebastian Kautzky Christian Pickem Christoph H örmann Source Type: research

Adjuvant hemoadsorption therapy in patients with severe COVID-19 and related organ failure requiring CRRT or ECMO therapy: A case series
CONCLUSIONS: In this case series of SARS-CoV-2 infected patients admitted to the intensive care unit with ARDS, we report effective interleukin (IL)-6 removal, reduced norepinephrine requirement, and improved lung function while receiving adjuvant, extracorporeal hemoadsorption therapy in the context of a multimodal treatment approach. The presented protocol for CytoSorb initiation may be a good foundation for the development of further prospective studies in the field and may eventually also be applied to other forms of hyperinflammatory ARDS.PMID:34256643 | DOI:10.1177/03913988211030517 (Source: The International Journal...
Source: The International Journal of Artificial Organs - July 14, 2021 Category: Transplant Surgery Authors: Florian Wunderlich-Sperl Sebastian Kautzky Christian Pickem Christoph H örmann Source Type: research

Adjuvant hemoadsorption therapy in patients with severe COVID-19 and related organ failure requiring CRRT or ECMO therapy: A case series
CONCLUSIONS: In this case series of SARS-CoV-2 infected patients admitted to the intensive care unit with ARDS, we report effective interleukin (IL)-6 removal, reduced norepinephrine requirement, and improved lung function while receiving adjuvant, extracorporeal hemoadsorption therapy in the context of a multimodal treatment approach. The presented protocol for CytoSorb initiation may be a good foundation for the development of further prospective studies in the field and may eventually also be applied to other forms of hyperinflammatory ARDS.PMID:34256643 | DOI:10.1177/03913988211030517 (Source: The International Journal...
Source: The International Journal of Artificial Organs - July 14, 2021 Category: Transplant Surgery Authors: Florian Wunderlich-Sperl Sebastian Kautzky Christian Pickem Christoph H örmann Source Type: research

Adjuvant hemoadsorption therapy in patients with severe COVID-19 and related organ failure requiring CRRT or ECMO therapy: A case series
CONCLUSIONS: In this case series of SARS-CoV-2 infected patients admitted to the intensive care unit with ARDS, we report effective interleukin (IL)-6 removal, reduced norepinephrine requirement, and improved lung function while receiving adjuvant, extracorporeal hemoadsorption therapy in the context of a multimodal treatment approach. The presented protocol for CytoSorb initiation may be a good foundation for the development of further prospective studies in the field and may eventually also be applied to other forms of hyperinflammatory ARDS.PMID:34256643 | DOI:10.1177/03913988211030517 (Source: The International Journal...
Source: The International Journal of Artificial Organs - July 14, 2021 Category: Transplant Surgery Authors: Florian Wunderlich-Sperl Sebastian Kautzky Christian Pickem Christoph H örmann Source Type: research

Outcomes of systemic anticoagulation with bivalirudin for Impella 5.0
Int J Artif Organs. 2021 Jul 12:3913988211032238. doi: 10.1177/03913988211032238. Online ahead of print.ABSTRACTTemporary mechanical circulatory support (tMCS) devices are used for the management of cardiogenic shock. The Impella 5.0 (Abiomed; Danvers, MA) (IMP5) is a commonly used, surgically implanted, tMCS device that requires systemic anticoagulation and purge solution to avoid pump failure. To avoid heparin-induced thrombocytopenia (HIT) from unfractionated heparin (UFH) use, our program has explored the utility of bivalirudin (BIV) for systemic anticoagulation in IMP5. This single center, retrospective study included...
Source: The International Journal of Artificial Organs - July 12, 2021 Category: Transplant Surgery Authors: Carly Fabrizio Marissa N Levito Ryan Rivosecchi Michael Bashline Brittany Slocum Arman Kilic Catalin Toma Holt Murray Raj Ramanan Jeffrey Fowler Gavin W Hickey Edward T Horn Source Type: research

In vivo study of the angiogenesis potential of bone marrow-derived mesenchymal stem cell aggregates in their niche like environment
Int J Artif Organs. 2021 Jul 10:3913988211025538. doi: 10.1177/03913988211025538. Online ahead of print.ABSTRACTBACKGROUND: Sufficient blood vessel formation in bioengineered tissues is essential in order to keep the viability of the organs. Impaired development of blood vasculatures results in failure of the implanted tissue. The cellular source which is seeded in the scaffold is one of the crucial factors involved in tissue engineering methods.MATERIALS AND METHODS: Considering the notable competence of Bone Marrow derived Mesenchymal Stem Cell aggregates for tissue engineering purposes, in this study BM-aggregates and e...
Source: The International Journal of Artificial Organs - July 12, 2021 Category: Transplant Surgery Authors: Sara Anajafi Azam Ranjbar Monireh Torabi-Rahvar Naser Ahmadbeigi Source Type: research

Outcomes of systemic anticoagulation with bivalirudin for Impella 5.0
Int J Artif Organs. 2021 Jul 12:3913988211032238. doi: 10.1177/03913988211032238. Online ahead of print.ABSTRACTTemporary mechanical circulatory support (tMCS) devices are used for the management of cardiogenic shock. The Impella 5.0 (Abiomed; Danvers, MA) (IMP5) is a commonly used, surgically implanted, tMCS device that requires systemic anticoagulation and purge solution to avoid pump failure. To avoid heparin-induced thrombocytopenia (HIT) from unfractionated heparin (UFH) use, our program has explored the utility of bivalirudin (BIV) for systemic anticoagulation in IMP5. This single center, retrospective study included...
Source: The International Journal of Artificial Organs - July 12, 2021 Category: Transplant Surgery Authors: Carly Fabrizio Marissa N Levito Ryan Rivosecchi Michael Bashline Brittany Slocum Arman Kilic Catalin Toma Holt Murray Raj Ramanan Jeffrey Fowler Gavin W Hickey Edward T Horn Source Type: research

In vivo study of the angiogenesis potential of bone marrow-derived mesenchymal stem cell aggregates in their niche like environment
Int J Artif Organs. 2021 Jul 10:3913988211025538. doi: 10.1177/03913988211025538. Online ahead of print.ABSTRACTBACKGROUND: Sufficient blood vessel formation in bioengineered tissues is essential in order to keep the viability of the organs. Impaired development of blood vasculatures results in failure of the implanted tissue. The cellular source which is seeded in the scaffold is one of the crucial factors involved in tissue engineering methods.MATERIALS AND METHODS: Considering the notable competence of Bone Marrow derived Mesenchymal Stem Cell aggregates for tissue engineering purposes, in this study BM-aggregates and e...
Source: The International Journal of Artificial Organs - July 12, 2021 Category: Transplant Surgery Authors: Sara Anajafi Azam Ranjbar Monireh Torabi-Rahvar Naser Ahmadbeigi Source Type: research

Do anti-platelet drugs improve duration of continuous renal replacement therapy? A retrospective cohort study in cardiac ICU patients
The objective of this study was to investigate the impact of anti-platelet drug/s on duration of continuous renal replacement therapy (CRRT) in those patients where anti-coagulants were not used due to certain contraindications and in cases where patients were on anti-platelet drugs and were given anti-coagulant during CRRT.METHOD: This single-center, retrospective cohort study was conducted using the medical records patients treated with CRRT in the cardiac ICU of the inpatient urban facility, located in North India. Data was collected from only those patients who received CRRT for the duration of at least 12 h. Patient's...
Source: The International Journal of Artificial Organs - July 9, 2021 Category: Transplant Surgery Authors: Vivek Gupta Naved Aslam Shibba Takkar Chhabra Vikas Makkar Bishav Mohan Samir Kapoor Vikram Pal Singh Rajiv Kumar Suvir Grover Gurkirat Kaur Suman Sethi Simran Kaur Abhishek Goyal Bhupinder Singh Gurbhej Singh Sarju Ralhan Gurpreet Singh Wander Source Type: research

Do anti-platelet drugs improve duration of continuous renal replacement therapy? A retrospective cohort study in cardiac ICU patients
The objective of this study was to investigate the impact of anti-platelet drug/s on duration of continuous renal replacement therapy (CRRT) in those patients where anti-coagulants were not used due to certain contraindications and in cases where patients were on anti-platelet drugs and were given anti-coagulant during CRRT.METHOD: This single-center, retrospective cohort study was conducted using the medical records patients treated with CRRT in the cardiac ICU of the inpatient urban facility, located in North India. Data was collected from only those patients who received CRRT for the duration of at least 12 h. Patient's...
Source: The International Journal of Artificial Organs - July 9, 2021 Category: Transplant Surgery Authors: Vivek Gupta Naved Aslam Shibba Takkar Chhabra Vikas Makkar Bishav Mohan Samir Kapoor Vikram Pal Singh Rajiv Kumar Suvir Grover Gurkirat Kaur Suman Sethi Simran Kaur Abhishek Goyal Bhupinder Singh Gurbhej Singh Sarju Ralhan Gurpreet Singh Wander Source Type: research

Do anti-platelet drugs improve duration of continuous renal replacement therapy? A retrospective cohort study in cardiac ICU patients
The objective of this study was to investigate the impact of anti-platelet drug/s on duration of continuous renal replacement therapy (CRRT) in those patients where anti-coagulants were not used due to certain contraindications and in cases where patients were on anti-platelet drugs and were given anti-coagulant during CRRT.METHOD: This single-center, retrospective cohort study was conducted using the medical records patients treated with CRRT in the cardiac ICU of the inpatient urban facility, located in North India. Data was collected from only those patients who received CRRT for the duration of at least 12 h. Patient's...
Source: The International Journal of Artificial Organs - July 9, 2021 Category: Transplant Surgery Authors: Vivek Gupta Naved Aslam Shibba Takkar Chhabra Vikas Makkar Bishav Mohan Samir Kapoor Vikram Pal Singh Rajiv Kumar Suvir Grover Gurkirat Kaur Suman Sethi Simran Kaur Abhishek Goyal Bhupinder Singh Gurbhej Singh Sarju Ralhan Gurpreet Singh Wander Source Type: research

Pharmacokinetics of meropenem during advanced organ support (ADVOS < sup > ® < /sup > ) and continuous renal replacement therapy
Int J Artif Organs. 2021 Jun 18:3913988211021101. doi: 10.1177/03913988211021101. Online ahead of print.ABSTRACTThe advanced organ support (ADVOS) system allows to eliminate water-soluble as well as protein-bound molecules. Despite its clinical features, to date nothing is known about the elimination of clinically relevant drugs such as antiinfectives. Therefore, we report a case treated with ADVOS, continuous renal replacement therapy (CRRT), and meropenem (1 g 8-hourly) for empiric sepsis therapy monitored by meropenem drug levels. ADVOS showed more efficient elimination of meropenem compared to CRRT which has to be cons...
Source: The International Journal of Artificial Organs - June 19, 2021 Category: Transplant Surgery Authors: Christina K önig Stefan Kluge Valentin Fuhrmann Dominik Jarczak Source Type: research

Experimental study on the efficacy of a hybrid artificial nerve: The hot dog method
CONCLUSIONS: The hot dog method is simple, safe, and easy to execute. This method can serve as a new neural reconstruction method that uses artificial nerves.PMID:34144663 | DOI:10.1177/03913988211026000 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - June 19, 2021 Category: Transplant Surgery Authors: Ryosuke Tamura Kazunobu Hashikawa Shunsuke Sakakibara Takeo Osaki Daiki Kitano Hayato Maruguchi Tadashi Nomura Daisuke Sugiyama Hiroto Terashi Source Type: research

Pharmacokinetics of meropenem during advanced organ support (ADVOS < sup > ® < /sup > ) and continuous renal replacement therapy
Int J Artif Organs. 2021 Jun 18:3913988211021101. doi: 10.1177/03913988211021101. Online ahead of print.ABSTRACTThe advanced organ support (ADVOS) system allows to eliminate water-soluble as well as protein-bound molecules. Despite its clinical features, to date nothing is known about the elimination of clinically relevant drugs such as antiinfectives. Therefore, we report a case treated with ADVOS, continuous renal replacement therapy (CRRT), and meropenem (1 g 8-hourly) for empiric sepsis therapy monitored by meropenem drug levels. ADVOS showed more efficient elimination of meropenem compared to CRRT which has to be cons...
Source: The International Journal of Artificial Organs - June 19, 2021 Category: Transplant Surgery Authors: Christina K önig Stefan Kluge Valentin Fuhrmann Dominik Jarczak Source Type: research

Experimental study on the efficacy of a hybrid artificial nerve: The hot dog method
CONCLUSIONS: The hot dog method is simple, safe, and easy to execute. This method can serve as a new neural reconstruction method that uses artificial nerves.PMID:34144663 | DOI:10.1177/03913988211026000 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - June 19, 2021 Category: Transplant Surgery Authors: Ryosuke Tamura Kazunobu Hashikawa Shunsuke Sakakibara Takeo Osaki Daiki Kitano Hayato Maruguchi Tadashi Nomura Daisuke Sugiyama Hiroto Terashi Source Type: research

Pharmacokinetics of meropenem during advanced organ support (ADVOS < sup > ® < /sup > ) and continuous renal replacement therapy
Int J Artif Organs. 2021 Jun 18:3913988211021101. doi: 10.1177/03913988211021101. Online ahead of print.ABSTRACTThe advanced organ support (ADVOS) system allows to eliminate water-soluble as well as protein-bound molecules. Despite its clinical features, to date nothing is known about the elimination of clinically relevant drugs such as antiinfectives. Therefore, we report a case treated with ADVOS, continuous renal replacement therapy (CRRT), and meropenem (1 g 8-hourly) for empiric sepsis therapy monitored by meropenem drug levels. ADVOS showed more efficient elimination of meropenem compared to CRRT which has to be cons...
Source: The International Journal of Artificial Organs - June 19, 2021 Category: Transplant Surgery Authors: Christina K önig Stefan Kluge Valentin Fuhrmann Dominik Jarczak Source Type: research

Experimental study on the efficacy of a hybrid artificial nerve: The hot dog method
CONCLUSIONS: The hot dog method is simple, safe, and easy to execute. This method can serve as a new neural reconstruction method that uses artificial nerves.PMID:34144663 | DOI:10.1177/03913988211026000 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - June 19, 2021 Category: Transplant Surgery Authors: Ryosuke Tamura Kazunobu Hashikawa Shunsuke Sakakibara Takeo Osaki Daiki Kitano Hayato Maruguchi Tadashi Nomura Daisuke Sugiyama Hiroto Terashi Source Type: research

Pharmacokinetics of meropenem during advanced organ support (ADVOS < sup > ® < /sup > ) and continuous renal replacement therapy
Int J Artif Organs. 2021 Jun 18:3913988211021101. doi: 10.1177/03913988211021101. Online ahead of print.ABSTRACTThe advanced organ support (ADVOS) system allows to eliminate water-soluble as well as protein-bound molecules. Despite its clinical features, to date nothing is known about the elimination of clinically relevant drugs such as antiinfectives. Therefore, we report a case treated with ADVOS, continuous renal replacement therapy (CRRT), and meropenem (1 g 8-hourly) for empiric sepsis therapy monitored by meropenem drug levels. ADVOS showed more efficient elimination of meropenem compared to CRRT which has to be cons...
Source: The International Journal of Artificial Organs - June 19, 2021 Category: Transplant Surgery Authors: Christina K önig Stefan Kluge Valentin Fuhrmann Dominik Jarczak Source Type: research

Experimental study on the efficacy of a hybrid artificial nerve: The hot dog method
CONCLUSIONS: The hot dog method is simple, safe, and easy to execute. This method can serve as a new neural reconstruction method that uses artificial nerves.PMID:34144663 | DOI:10.1177/03913988211026000 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - June 19, 2021 Category: Transplant Surgery Authors: Ryosuke Tamura Kazunobu Hashikawa Shunsuke Sakakibara Takeo Osaki Daiki Kitano Hayato Maruguchi Tadashi Nomura Daisuke Sugiyama Hiroto Terashi Source Type: research

Pharmacokinetics of meropenem during advanced organ support (ADVOS < sup > ® < /sup > ) and continuous renal replacement therapy
Int J Artif Organs. 2021 Jun 18:3913988211021101. doi: 10.1177/03913988211021101. Online ahead of print.ABSTRACTThe advanced organ support (ADVOS) system allows to eliminate water-soluble as well as protein-bound molecules. Despite its clinical features, to date nothing is known about the elimination of clinically relevant drugs such as antiinfectives. Therefore, we report a case treated with ADVOS, continuous renal replacement therapy (CRRT), and meropenem (1 g 8-hourly) for empiric sepsis therapy monitored by meropenem drug levels. ADVOS showed more efficient elimination of meropenem compared to CRRT which has to be cons...
Source: The International Journal of Artificial Organs - June 19, 2021 Category: Transplant Surgery Authors: Christina K önig Stefan Kluge Valentin Fuhrmann Dominik Jarczak Source Type: research

Experimental study on the efficacy of a hybrid artificial nerve: The hot dog method
CONCLUSIONS: The hot dog method is simple, safe, and easy to execute. This method can serve as a new neural reconstruction method that uses artificial nerves.PMID:34144663 | DOI:10.1177/03913988211026000 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - June 19, 2021 Category: Transplant Surgery Authors: Ryosuke Tamura Kazunobu Hashikawa Shunsuke Sakakibara Takeo Osaki Daiki Kitano Hayato Maruguchi Tadashi Nomura Daisuke Sugiyama Hiroto Terashi Source Type: research

Pharmacokinetics of meropenem during advanced organ support (ADVOS < sup > ® < /sup > ) and continuous renal replacement therapy
Int J Artif Organs. 2021 Jun 18:3913988211021101. doi: 10.1177/03913988211021101. Online ahead of print.ABSTRACTThe advanced organ support (ADVOS) system allows to eliminate water-soluble as well as protein-bound molecules. Despite its clinical features, to date nothing is known about the elimination of clinically relevant drugs such as antiinfectives. Therefore, we report a case treated with ADVOS, continuous renal replacement therapy (CRRT), and meropenem (1 g 8-hourly) for empiric sepsis therapy monitored by meropenem drug levels. ADVOS showed more efficient elimination of meropenem compared to CRRT which has to be cons...
Source: The International Journal of Artificial Organs - June 19, 2021 Category: Transplant Surgery Authors: Christina K önig Stefan Kluge Valentin Fuhrmann Dominik Jarczak Source Type: research

Experimental study on the efficacy of a hybrid artificial nerve: The hot dog method
CONCLUSIONS: The hot dog method is simple, safe, and easy to execute. This method can serve as a new neural reconstruction method that uses artificial nerves.PMID:34144663 | DOI:10.1177/03913988211026000 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - June 19, 2021 Category: Transplant Surgery Authors: Ryosuke Tamura Kazunobu Hashikawa Shunsuke Sakakibara Takeo Osaki Daiki Kitano Hayato Maruguchi Tadashi Nomura Daisuke Sugiyama Hiroto Terashi Source Type: research

Pharmacokinetics of meropenem during advanced organ support (ADVOS < sup > ® < /sup > ) and continuous renal replacement therapy
Int J Artif Organs. 2021 Jun 18:3913988211021101. doi: 10.1177/03913988211021101. Online ahead of print.ABSTRACTThe advanced organ support (ADVOS) system allows to eliminate water-soluble as well as protein-bound molecules. Despite its clinical features, to date nothing is known about the elimination of clinically relevant drugs such as antiinfectives. Therefore, we report a case treated with ADVOS, continuous renal replacement therapy (CRRT), and meropenem (1 g 8-hourly) for empiric sepsis therapy monitored by meropenem drug levels. ADVOS showed more efficient elimination of meropenem compared to CRRT which has to be cons...
Source: The International Journal of Artificial Organs - June 19, 2021 Category: Transplant Surgery Authors: Christina K önig Stefan Kluge Valentin Fuhrmann Dominik Jarczak Source Type: research

Experimental study on the efficacy of a hybrid artificial nerve: The hot dog method
CONCLUSIONS: The hot dog method is simple, safe, and easy to execute. This method can serve as a new neural reconstruction method that uses artificial nerves.PMID:34144663 | DOI:10.1177/03913988211026000 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - June 19, 2021 Category: Transplant Surgery Authors: Ryosuke Tamura Kazunobu Hashikawa Shunsuke Sakakibara Takeo Osaki Daiki Kitano Hayato Maruguchi Tadashi Nomura Daisuke Sugiyama Hiroto Terashi Source Type: research

Pharmacokinetics of meropenem during advanced organ support (ADVOS < sup > ® < /sup > ) and continuous renal replacement therapy
Int J Artif Organs. 2021 Jun 18:3913988211021101. doi: 10.1177/03913988211021101. Online ahead of print.ABSTRACTThe advanced organ support (ADVOS) system allows to eliminate water-soluble as well as protein-bound molecules. Despite its clinical features, to date nothing is known about the elimination of clinically relevant drugs such as antiinfectives. Therefore, we report a case treated with ADVOS, continuous renal replacement therapy (CRRT), and meropenem (1 g 8-hourly) for empiric sepsis therapy monitored by meropenem drug levels. ADVOS showed more efficient elimination of meropenem compared to CRRT which has to be cons...
Source: The International Journal of Artificial Organs - June 19, 2021 Category: Transplant Surgery Authors: Christina K önig Stefan Kluge Valentin Fuhrmann Dominik Jarczak Source Type: research

Experimental study on the efficacy of a hybrid artificial nerve: The hot dog method
CONCLUSIONS: The hot dog method is simple, safe, and easy to execute. This method can serve as a new neural reconstruction method that uses artificial nerves.PMID:34144663 | DOI:10.1177/03913988211026000 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - June 19, 2021 Category: Transplant Surgery Authors: Ryosuke Tamura Kazunobu Hashikawa Shunsuke Sakakibara Takeo Osaki Daiki Kitano Hayato Maruguchi Tadashi Nomura Daisuke Sugiyama Hiroto Terashi Source Type: research

Pharmacokinetics of meropenem during advanced organ support (ADVOS < sup > ® < /sup > ) and continuous renal replacement therapy
Int J Artif Organs. 2021 Jun 18:3913988211021101. doi: 10.1177/03913988211021101. Online ahead of print.ABSTRACTThe advanced organ support (ADVOS) system allows to eliminate water-soluble as well as protein-bound molecules. Despite its clinical features, to date nothing is known about the elimination of clinically relevant drugs such as antiinfectives. Therefore, we report a case treated with ADVOS, continuous renal replacement therapy (CRRT), and meropenem (1 g 8-hourly) for empiric sepsis therapy monitored by meropenem drug levels. ADVOS showed more efficient elimination of meropenem compared to CRRT which has to be cons...
Source: The International Journal of Artificial Organs - June 19, 2021 Category: Transplant Surgery Authors: Christina K önig Stefan Kluge Valentin Fuhrmann Dominik Jarczak Source Type: research

Experimental study on the efficacy of a hybrid artificial nerve: The hot dog method
CONCLUSIONS: The hot dog method is simple, safe, and easy to execute. This method can serve as a new neural reconstruction method that uses artificial nerves.PMID:34144663 | DOI:10.1177/03913988211026000 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - June 19, 2021 Category: Transplant Surgery Authors: Ryosuke Tamura Kazunobu Hashikawa Shunsuke Sakakibara Takeo Osaki Daiki Kitano Hayato Maruguchi Tadashi Nomura Daisuke Sugiyama Hiroto Terashi Source Type: research

Pharmacokinetics of meropenem during advanced organ support (ADVOS < sup > ® < /sup > ) and continuous renal replacement therapy
Int J Artif Organs. 2021 Jun 18:3913988211021101. doi: 10.1177/03913988211021101. Online ahead of print.ABSTRACTThe advanced organ support (ADVOS) system allows to eliminate water-soluble as well as protein-bound molecules. Despite its clinical features, to date nothing is known about the elimination of clinically relevant drugs such as antiinfectives. Therefore, we report a case treated with ADVOS, continuous renal replacement therapy (CRRT), and meropenem (1 g 8-hourly) for empiric sepsis therapy monitored by meropenem drug levels. ADVOS showed more efficient elimination of meropenem compared to CRRT which has to be cons...
Source: The International Journal of Artificial Organs - June 19, 2021 Category: Transplant Surgery Authors: Christina K önig Stefan Kluge Valentin Fuhrmann Dominik Jarczak Source Type: research

Experimental study on the efficacy of a hybrid artificial nerve: The hot dog method
CONCLUSIONS: The hot dog method is simple, safe, and easy to execute. This method can serve as a new neural reconstruction method that uses artificial nerves.PMID:34144663 | DOI:10.1177/03913988211026000 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - June 19, 2021 Category: Transplant Surgery Authors: Ryosuke Tamura Kazunobu Hashikawa Shunsuke Sakakibara Takeo Osaki Daiki Kitano Hayato Maruguchi Tadashi Nomura Daisuke Sugiyama Hiroto Terashi Source Type: research

Pharmacokinetics of meropenem during advanced organ support (ADVOS < sup > ® < /sup > ) and continuous renal replacement therapy
Int J Artif Organs. 2021 Jun 18:3913988211021101. doi: 10.1177/03913988211021101. Online ahead of print.ABSTRACTThe advanced organ support (ADVOS) system allows to eliminate water-soluble as well as protein-bound molecules. Despite its clinical features, to date nothing is known about the elimination of clinically relevant drugs such as antiinfectives. Therefore, we report a case treated with ADVOS, continuous renal replacement therapy (CRRT), and meropenem (1 g 8-hourly) for empiric sepsis therapy monitored by meropenem drug levels. ADVOS showed more efficient elimination of meropenem compared to CRRT which has to be cons...
Source: The International Journal of Artificial Organs - June 19, 2021 Category: Transplant Surgery Authors: Christina K önig Stefan Kluge Valentin Fuhrmann Dominik Jarczak Source Type: research

Experimental study on the efficacy of a hybrid artificial nerve: The hot dog method
CONCLUSIONS: The hot dog method is simple, safe, and easy to execute. This method can serve as a new neural reconstruction method that uses artificial nerves.PMID:34144663 | DOI:10.1177/03913988211026000 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - June 19, 2021 Category: Transplant Surgery Authors: Ryosuke Tamura Kazunobu Hashikawa Shunsuke Sakakibara Takeo Osaki Daiki Kitano Hayato Maruguchi Tadashi Nomura Daisuke Sugiyama Hiroto Terashi Source Type: research

Pharmacokinetics of meropenem during advanced organ support (ADVOS < sup > ® < /sup > ) and continuous renal replacement therapy
Int J Artif Organs. 2021 Jun 18:3913988211021101. doi: 10.1177/03913988211021101. Online ahead of print.ABSTRACTThe advanced organ support (ADVOS) system allows to eliminate water-soluble as well as protein-bound molecules. Despite its clinical features, to date nothing is known about the elimination of clinically relevant drugs such as antiinfectives. Therefore, we report a case treated with ADVOS, continuous renal replacement therapy (CRRT), and meropenem (1 g 8-hourly) for empiric sepsis therapy monitored by meropenem drug levels. ADVOS showed more efficient elimination of meropenem compared to CRRT which has to be cons...
Source: The International Journal of Artificial Organs - June 19, 2021 Category: Transplant Surgery Authors: Christina K önig Stefan Kluge Valentin Fuhrmann Dominik Jarczak Source Type: research

Experimental study on the efficacy of a hybrid artificial nerve: The hot dog method
CONCLUSIONS: The hot dog method is simple, safe, and easy to execute. This method can serve as a new neural reconstruction method that uses artificial nerves.PMID:34144663 | DOI:10.1177/03913988211026000 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - June 19, 2021 Category: Transplant Surgery Authors: Ryosuke Tamura Kazunobu Hashikawa Shunsuke Sakakibara Takeo Osaki Daiki Kitano Hayato Maruguchi Tadashi Nomura Daisuke Sugiyama Hiroto Terashi Source Type: research

Pharmacokinetics of meropenem during advanced organ support (ADVOS < sup > ® < /sup > ) and continuous renal replacement therapy
Int J Artif Organs. 2021 Jun 18:3913988211021101. doi: 10.1177/03913988211021101. Online ahead of print.ABSTRACTThe advanced organ support (ADVOS) system allows to eliminate water-soluble as well as protein-bound molecules. Despite its clinical features, to date nothing is known about the elimination of clinically relevant drugs such as antiinfectives. Therefore, we report a case treated with ADVOS, continuous renal replacement therapy (CRRT), and meropenem (1 g 8-hourly) for empiric sepsis therapy monitored by meropenem drug levels. ADVOS showed more efficient elimination of meropenem compared to CRRT which has to be cons...
Source: The International Journal of Artificial Organs - June 19, 2021 Category: Transplant Surgery Authors: Christina K önig Stefan Kluge Valentin Fuhrmann Dominik Jarczak Source Type: research

Experimental study on the efficacy of a hybrid artificial nerve: The hot dog method
CONCLUSIONS: The hot dog method is simple, safe, and easy to execute. This method can serve as a new neural reconstruction method that uses artificial nerves.PMID:34144663 | DOI:10.1177/03913988211026000 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - June 19, 2021 Category: Transplant Surgery Authors: Ryosuke Tamura Kazunobu Hashikawa Shunsuke Sakakibara Takeo Osaki Daiki Kitano Hayato Maruguchi Tadashi Nomura Daisuke Sugiyama Hiroto Terashi Source Type: research

Pharmacokinetics of meropenem during advanced organ support (ADVOS < sup > ® < /sup > ) and continuous renal replacement therapy
Int J Artif Organs. 2021 Jun 18:3913988211021101. doi: 10.1177/03913988211021101. Online ahead of print.ABSTRACTThe advanced organ support (ADVOS) system allows to eliminate water-soluble as well as protein-bound molecules. Despite its clinical features, to date nothing is known about the elimination of clinically relevant drugs such as antiinfectives. Therefore, we report a case treated with ADVOS, continuous renal replacement therapy (CRRT), and meropenem (1 g 8-hourly) for empiric sepsis therapy monitored by meropenem drug levels. ADVOS showed more efficient elimination of meropenem compared to CRRT which has to be cons...
Source: The International Journal of Artificial Organs - June 19, 2021 Category: Transplant Surgery Authors: Christina K önig Stefan Kluge Valentin Fuhrmann Dominik Jarczak Source Type: research

Experimental study on the efficacy of a hybrid artificial nerve: The hot dog method
CONCLUSIONS: The hot dog method is simple, safe, and easy to execute. This method can serve as a new neural reconstruction method that uses artificial nerves.PMID:34144663 | DOI:10.1177/03913988211026000 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - June 19, 2021 Category: Transplant Surgery Authors: Ryosuke Tamura Kazunobu Hashikawa Shunsuke Sakakibara Takeo Osaki Daiki Kitano Hayato Maruguchi Tadashi Nomura Daisuke Sugiyama Hiroto Terashi Source Type: research

Pharmacokinetics of meropenem during advanced organ support (ADVOS < sup > ® < /sup > ) and continuous renal replacement therapy
Int J Artif Organs. 2021 Jun 18:3913988211021101. doi: 10.1177/03913988211021101. Online ahead of print.ABSTRACTThe advanced organ support (ADVOS) system allows to eliminate water-soluble as well as protein-bound molecules. Despite its clinical features, to date nothing is known about the elimination of clinically relevant drugs such as antiinfectives. Therefore, we report a case treated with ADVOS, continuous renal replacement therapy (CRRT), and meropenem (1 g 8-hourly) for empiric sepsis therapy monitored by meropenem drug levels. ADVOS showed more efficient elimination of meropenem compared to CRRT which has to be cons...
Source: The International Journal of Artificial Organs - June 19, 2021 Category: Transplant Surgery Authors: Christina K önig Stefan Kluge Valentin Fuhrmann Dominik Jarczak Source Type: research

Experimental study on the efficacy of a hybrid artificial nerve: The hot dog method
CONCLUSIONS: The hot dog method is simple, safe, and easy to execute. This method can serve as a new neural reconstruction method that uses artificial nerves.PMID:34144663 | DOI:10.1177/03913988211026000 (Source: The International Journal of Artificial Organs)
Source: The International Journal of Artificial Organs - June 19, 2021 Category: Transplant Surgery Authors: Ryosuke Tamura Kazunobu Hashikawa Shunsuke Sakakibara Takeo Osaki Daiki Kitano Hayato Maruguchi Tadashi Nomura Daisuke Sugiyama Hiroto Terashi Source Type: research