Citrate anticoagulation and systemic heparin anticoagulation during continuous renal replacement therapy among critically-ill children

CONCLUSION: RCA is a safe and effective anticoagulation method for CRRT in critically-ill children and it prolongs hemofilter survival.IMPACT: RCA is superior to systemic heparin for the prolongation of circuit survival (overall and for clotting-related loss) during CRRT. These data indicate that RCA can be used to maximize the effective delivery of CRRT in critically-ill patients admitted to the PICU. There are potential cost-saving implications from our results owing to benefits such as less circuit downtime and fewer circuit changes.PMID:38555381 | DOI:10.1038/s41390-024-03163-x
Source: Pediatric Research - Category: Pediatrics Authors: Source Type: research