Immunohistochemical characterization of a steroid secreting oncocytic adrenal carcinoma responsible for paraneoplastic hyperparathyroidism
We report a unique case of a 44-year-old man with paraneoplastic hyperparathyroidism due to an oncocytic adrenocortical carcinoma (stage pT3N0R0M0, ENSAT 2 with a 4% Ki-67). Paraneoplastic hyperparathyroidism was associated with mild ACTH-independent hypercortisolism and increased estradiol secretion responsible for gynecomastia and hypogonadism. Biological investigations performed in blood samples from peripheral and adrenal veins revealed that the tumor secreted PTH and estradiol. Ectopic PTH secretion was confirmed by abnormally high expression of PTH mRNA and clusters of PTH immunoreactive cells in the tumor tissue. Do...
Source: European Journal of Endocrinology - March 4, 2023 Category: Endocrinology Authors: Haissaguerre Magalie Louiset Estelle Juhlin C Christofer Stenman Adam Laurent Christophe Trouette H élène Lefebvre Herv é Tabarin Antoine Source Type: research
Genes, Vol. 14, Pages 647: The Klinefelter Syndrome and Testicular Sperm Retrieval Outcomes
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Klinefelter syndrome (KS), caused by the presence of an extra X chromosome, is the most prevalent chromosomal sexual anomaly, with an estimated incidence of 1:500/1000 per male live birth (karyotype 47,XXY). High stature, tiny testicles, small penis, gynecomastia, feminine body proportions and hair, visceral obesity, and testicular failure are all symptoms of KS. Endocrine (osteoporosis, obesity, diabetes), musculoskeletal, cardiovascular, autoimmune disorders, cancer, neurocognitive disabilities, and infertility are also outcomes of KS. Causal theories are discussed in addition to hormonal characteristics and tes...
Source: Genes - March 4, 2023 Category: Genetics & Stem Cells Authors: Ros ália Sá Lu ís Ferraz Alberto Barros M ário Sousa Tags: Review Source Type: research
5G-Based Telerobotic Ultrasound System Improves Access to Breast Examination in Rural and Remote Areas: A Prospective and Two-Scenario Study
CONCLUSION: The 5G-based telerobotic US system is feasible for providing effective breast examinations in rural and remote areas.PMID:36766467 | DOI:10.3390/diagnostics13030362 (Source: Rural Remote Health)
Source: Rural Remote Health - February 11, 2023 Category: Rural Health Authors: Tian He Yin-Ying Pu Ya-Qin Zhang Zhe-Bin Qian Le-Hang Guo Li-Ping Sun Chong-Ke Zhao Hui-Xiong Xu Source Type: research
5G-Based Telerobotic Ultrasound System Improves Access to Breast Examination in Rural and Remote Areas: A Prospective and Two-Scenario Study
CONCLUSION: The 5G-based telerobotic US system is feasible for providing effective breast examinations in rural and remote areas.PMID:36766467 | DOI:10.3390/diagnostics13030362 (Source: Rural Remote Health)
Source: Rural Remote Health - February 11, 2023 Category: Rural Health Authors: Tian He Yin-Ying Pu Ya-Qin Zhang Zhe-Bin Qian Le-Hang Guo Li-Ping Sun Chong-Ke Zhao Hui-Xiong Xu Source Type: research
5G-Based Telerobotic Ultrasound System Improves Access to Breast Examination in Rural and Remote Areas: A Prospective and Two-Scenario Study
CONCLUSION: The 5G-based telerobotic US system is feasible for providing effective breast examinations in rural and remote areas.PMID:36766467 | PMC:PMC9913989 | DOI:10.3390/diagnostics13030362 (Source: Rural Remote Health)
Source: Rural Remote Health - February 11, 2023 Category: Rural Health Authors: Tian He Yin-Ying Pu Ya-Qin Zhang Zhe-Bin Qian Le-Hang Guo Li-Ping Sun Chong-Ke Zhao Hui-Xiong Xu Source Type: research
Increased Morbidity in Males Diagnosed with Gynecomastia: A nationwide register-based cohort study
CONCLUSIONS: The presence of idiopathic gynecomastia is an important first clinical symptom of an underlying disease and a significant predictor of future disease risk. These findings should stimulate more awareness among health care providers to increase identification of gynecomastia and its causes in males.PMID:36718997 | DOI:10.1210/clinem/dgad048 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - January 31, 2023 Category: Endocrinology Authors: Cecilie S Uldbjerg Youn-Hee Lim Elvira V Br äuner Anders Juul Source Type: research
Integrating the Fast-Track surgery concept into the surgical treatment of gynecomastia
Conclusions: The proposed fast-track pathway is feasible for surgical treatment of gynecomastia, leading to an enhanced recovery and high patient satisfaction without increasing the rate of complications. The fast-track surgery concept with implementation of local anesthetic techniques should be given serious consideration in gynecomastia management.PMID:36650940 | DOI:10.1080/2000656X.2023.2166946 (Source: Hand Surgery)
Source: Hand Surgery - January 18, 2023 Category: Surgery Authors: Jinguang He Jiafei Yang Tingting Dai Jiao Wei Source Type: research
Integrating the Fast-Track surgery concept into the surgical treatment of gynecomastia
Conclusions: The proposed fast-track pathway is feasible for surgical treatment of gynecomastia, leading to an enhanced recovery and high patient satisfaction without increasing the rate of complications. The fast-track surgery concept with implementation of local anesthetic techniques should be given serious consideration in gynecomastia management.PMID:36650940 | DOI:10.1080/2000656X.2023.2166946 (Source: Journal of Plastic Surgery and Hand Surgery)
Source: Journal of Plastic Surgery and Hand Surgery - January 18, 2023 Category: Surgery Authors: Jinguang He Jiafei Yang Tingting Dai Jiao Wei Source Type: research
Integrating the Fast-Track surgery concept into the surgical treatment of gynecomastia
Conclusions: The proposed fast-track pathway is feasible for surgical treatment of gynecomastia, leading to an enhanced recovery and high patient satisfaction without increasing the rate of complications. The fast-track surgery concept with implementation of local anesthetic techniques should be given serious consideration in gynecomastia management.PMID:36650940 | DOI:10.1080/2000656X.2023.2166946 (Source: Hand Surgery)
Source: Hand Surgery - January 18, 2023 Category: Surgery Authors: Jinguang He Jiafei Yang Tingting Dai Jiao Wei Source Type: research
Integrating the Fast-Track surgery concept into the surgical treatment of gynecomastia
Conclusions: The proposed fast-track pathway is feasible for surgical treatment of gynecomastia, leading to an enhanced recovery and high patient satisfaction without increasing the rate of complications. The fast-track surgery concept with implementation of local anesthetic techniques should be given serious consideration in gynecomastia management.PMID:36650940 | DOI:10.1080/2000656X.2023.2166946 (Source: Journal of Plastic Surgery and Hand Surgery)
Source: Journal of Plastic Surgery and Hand Surgery - January 18, 2023 Category: Surgery Authors: Jinguang He Jiafei Yang Tingting Dai Jiao Wei Source Type: research
Extracardiac findings with increased perfusion during clinical O-15-H2O PET/CT myocardial perfusion imaging: A case series
ConclusionsMalignant and benign extracardiac coincidental findings with increased perfusion are readily visible and frequently seen on O-15-H2O PET MPI. We recommend evaluating the summed O-15-H2O PET images in addition to the low-dose CT attenuation images. (Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - January 5, 2023 Category: Nuclear Medicine Source Type: research
Anabolic –androgenic steroids: How do they work and what are the risks?
Anabolic–androgenic steroids (AAS) are a class of hormones that are widely abused for their muscle-building and strength-increasing properties in high, nontherapeutic, dosages. This review provides an up-to-date and comprehensive overview on how these hormones work and what side effects they might elicit. We discuss how AAS are absorbed into the circulation after intramuscular injection or oral ingestion and how they are subsequently transported to the tissues, where they will move into the extravascular compartment and diffuse into their target cells. Inside these cells, AAS can biotransform into different metabolites o...
Source: Frontiers in Endocrinology - December 19, 2022 Category: Endocrinology Source Type: research
Efficacy and Safety of Cold-Induced Noninvasive Targeted Fat Reduction in Pseudogynecomastia
CONCLUSION: Cryolipolysis was demonstrated to be an effective and safe option for reducing breast fat in pseudogynecomastia. Male with mild to moderate breast enlargement without skin excess can be ideal candidates.PMID:36478423 | DOI:10.5021/ad.21.180 (Source: Annals of Dermatology)
Source: Annals of Dermatology - December 8, 2022 Category: Dermatology Authors: Ji Yeon Hong Su Jung Park Soo Yeon Kim Beom Joon Kim Source Type: research
