Sex Differences Between Female and Male Individuals in Antipsychotic Efficacy and Adverse Effects in the Treatment of Schizophrenia
ConclusionsWhile overall sex differences were limited across efficacy and tolerability for antipsychotic treatment, there were some specific findings with risperidone. Further examination of sex differences within antipsychotic trials will be important to improve efficacy and reduce adverse responses across as well as individualising care for people with schizophrenia. (Source: CNS Drugs)
Source: CNS Drugs - May 7, 2024 Category: Neurology Source Type: research

Peripubertal gynecomastia for Apollo?
Ann Endocrinol (Paris). 2024 Apr 10:S0003-4266(24)00048-9. doi: 10.1016/j.ando.2024.03.003. Online ahead of print.NO ABSTRACTPMID:38704308 | DOI:10.1016/j.ando.2024.03.003 (Source: Annales d'Endocrinologie)
Source: Annales d'Endocrinologie - May 4, 2024 Category: Endocrinology Authors: Philippe Charlier Source Type: research

Peripubertal gynecomastia for Apollo?
Ann Endocrinol (Paris). 2024 Apr 10:S0003-4266(24)00048-9. doi: 10.1016/j.ando.2024.03.003. Online ahead of print.NO ABSTRACTPMID:38704308 | DOI:10.1016/j.ando.2024.03.003 (Source: Annales d'Endocrinologie)
Source: Annales d'Endocrinologie - May 4, 2024 Category: Endocrinology Authors: Philippe Charlier Source Type: research

Peripubertal gynecomastia for Apollo?
Ann Endocrinol (Paris). 2024 Apr 10:S0003-4266(24)00048-9. doi: 10.1016/j.ando.2024.03.003. Online ahead of print.NO ABSTRACTPMID:38704308 | DOI:10.1016/j.ando.2024.03.003 (Source: Annales d'Endocrinologie)
Source: Annales d'Endocrinologie - May 4, 2024 Category: Endocrinology Authors: Philippe Charlier Source Type: research

Peripubertal gynecomastia for Apollo?
Ann Endocrinol (Paris). 2024 Apr 10:S0003-4266(24)00048-9. doi: 10.1016/j.ando.2024.03.003. Online ahead of print.NO ABSTRACTPMID:38704308 | DOI:10.1016/j.ando.2024.03.003 (Source: Annales d'Endocrinologie)
Source: Annales d'Endocrinologie - May 4, 2024 Category: Endocrinology Authors: Philippe Charlier Source Type: research

Screening Mammography for Males With Elevated Breast Cancer Risk, Mutation Carriers, and Gynecomastia
CONCLUSION: Gynecomastia may be associated with an increased risk of breast cancer in carriers. Larger studies are needed to determine whether and when to screen male carriers.PMID:38670861 | DOI:10.1016/j.clbc.2024.03.014 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - April 26, 2024 Category: Cancer & Oncology Authors: Ahuva Grubstein Marva Dahan Wael Jomar Tal Friehmann Shlomit Tamir Tzippy Shochat Eli Atar Tanir M Allweis Source Type: research

Screening Mammography for Males With Elevated Breast Cancer Risk, Mutation Carriers, and Gynecomastia
CONCLUSION: Gynecomastia may be associated with an increased risk of breast cancer in carriers. Larger studies are needed to determine whether and when to screen male carriers.PMID:38670861 | DOI:10.1016/j.clbc.2024.03.014 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - April 26, 2024 Category: Cancer & Oncology Authors: Ahuva Grubstein Marva Dahan Wael Jomar Tal Friehmann Shlomit Tamir Tzippy Shochat Eli Atar Tanir M Allweis Source Type: research

Anthropometric indices fail to predict complications after mastectomy for gynecomastia in adolescents
Gynecomastia is the abnormal enlargement of male glandular breast tissue. It is common during puberty and typically resolves spontaneously. However, approximately 10% of patients experience persistent and often permanent breast enlargement. Gynecomastia can have negative psychological effects on adolescents and may predispose them to depression, anxiety, low self-esteem, and reduced quality of life.1,2 Although routine management involves watchful waiting, there is evidence suggesting that surgical intervention before age 18 may lead to better psychosocial outcomes. (Source: Journal of Plastic, Reconstructive and Aesthetic Surgery)
Source: Journal of Plastic, Reconstructive and Aesthetic Surgery - April 12, 2024 Category: Cosmetic Surgery Authors: Matthew J. Heron, Rafael Felix P. Tiongco, Katherine J. Zhu, Mehran Habibi, Carisa M. Cooney, Kristen P. Broderick Source Type: research

Infra-areolar subcutaneous mastectomy in the surgical treatment of adolescent gynecomastia
ConclusionsThe results of infra-areolar subcutaneous mastectomy are very promising in pubertal gynecomastia due to good skin elasticity and without obesity in the adolescent age group. We believe that this method provides an almost invisible incision and a natural pectoral appearance for adolescent patients who have experienced serious emotional problems related to their body images. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - March 27, 2024 Category: Surgery Source Type: research

Gynecomastia Surgery in 4996 Male Patients Over 14 Years: A Retrospective Analysis of Surgical Trends, Predictive Risk Factors, and Short-Term Outcomes
CONCLUSION: In this study, we analyzed 4996 male adult GS patients from the ACS-NSQIP database, revealing an increased caseload and significant general surgeon involvement. Risk factors like bleeding disorders, inpatient status, and prior sepsis were linked to postoperative complications, while BMI was crucial for predicting adverse events. Overall, our findings may aid in enhancing patient care through advanced preoperative screening and closer perioperative management.LEVEL OF EVIDENCE III: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medici...
Source: Hand Surgery - March 26, 2024 Category: Surgery Authors: Leonard Knoedler Samuel Knoedler Michael Alfertshofer Frederik J Hansen Thilo Schenck Giuseppe Sofo Doha Obed Katharina Hollmann Laura C Siegwart Felix H Vollbach Amir K Bigdeli Martin Kauke-Navarro Bohdan Pomahac Source Type: research

Gynecomastia Surgery in 4996 Male Patients Over 14 Years: A Retrospective Analysis of Surgical Trends, Predictive Risk Factors, and Short-Term Outcomes
CONCLUSION: In this study, we analyzed 4996 male adult GS patients from the ACS-NSQIP database, revealing an increased caseload and significant general surgeon involvement. Risk factors like bleeding disorders, inpatient status, and prior sepsis were linked to postoperative complications, while BMI was crucial for predicting adverse events. Overall, our findings may aid in enhancing patient care through advanced preoperative screening and closer perioperative management.LEVEL OF EVIDENCE III: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medici...
Source: Hand Surgery - March 26, 2024 Category: Surgery Authors: Leonard Knoedler Samuel Knoedler Michael Alfertshofer Frederik J Hansen Thilo Schenck Giuseppe Sofo Doha Obed Katharina Hollmann Laura C Siegwart Felix H Vollbach Amir K Bigdeli Martin Kauke-Navarro Bohdan Pomahac Source Type: research

Gynecomastia Surgery in 4996 Male Patients Over 14 Years: A Retrospective Analysis of Surgical Trends, Predictive Risk Factors, and Short-Term Outcomes
ConclusionIn this study, we analyzed 4996 male adult GS patients from the ACS-NSQIP database, revealing an increased caseload and significant general surgeon involvement. Risk factors like bleeding disorders, inpatient status, and prior sepsis were linked to postoperative complications, while BMI was crucial for predicting adverse events. Overall, our findings may aid in enhancing patient care through advanced preoperative screening and closer perioperative management.Level of Evidence IIIThis journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine r...
Source: Aesthetic Plastic Surgery - March 25, 2024 Category: Cosmetic Surgery Source Type: research

Comparison of different medical treatments for primary hyperaldosteronism: a systematic review and network meta-analysis
CONCLUSION: The present NMA indicated that the blood pressure reduction and potassium-correcting effects of the three MRAs may demonstrate marginal differences, with confidence levels in the evidence being very low. Therefore, further research is needed to explore the efficacy of these MRAs, especially regarding their impact on mortality and cardiovascular outcomes.TRIAL REGISTRATION: PROSPERO (CRD: 42023446811).PMID:38511069 | PMC:PMC10953100 | DOI:10.1177/20406223241239775 (Source: Adv Data)
Source: Adv Data - March 21, 2024 Category: Epidemiology Authors: Wen-Yu Ho Ching-Chung Hsiao Ping-Hsun Wu Jui-Yi Chen Yu-Kang Tu Vin-Cent Wu Jia-Jin Chen Source Type: research

Comparison of different medical treatments for primary hyperaldosteronism: a systematic review and network meta-analysis
CONCLUSION: The present NMA indicated that the blood pressure reduction and potassium-correcting effects of the three MRAs may demonstrate marginal differences, with confidence levels in the evidence being very low. Therefore, further research is needed to explore the efficacy of these MRAs, especially regarding their impact on mortality and cardiovascular outcomes.TRIAL REGISTRATION: PROSPERO (CRD: 42023446811).PMID:38511069 | PMC:PMC10953100 | DOI:10.1177/20406223241239775 (Source: Adv Data)
Source: Adv Data - March 21, 2024 Category: Epidemiology Authors: Wen-Yu Ho Ching-Chung Hsiao Ping-Hsun Wu Jui-Yi Chen Yu-Kang Tu Vin-Cent Wu Jia-Jin Chen Source Type: research