Klinefelter syndrome: more than hypogonadism
Klinefelter syndrome (KS) is the most frequent chromosome disorder in males (1:650 newborn males), defined by 47,XXY karyotype. The classical phenotype is that of a tall male with relatively long legs, small, firm testes and gynecomastia. Azoospermia and infertility are almost inevitably present, but may be overcome by TESE and ICSI. Nevertheless, a broad spectrum of phenotypes has been described and>70% of the actually existing KS men may remain undiagnosed throughout their lifespan. Accordingly, hypogonadism is usually not evident until early adulthood and progresses with ageing. (Source: Metabolism - Clinical and Experimental)
Source: Metabolism - Clinical and Experimental - February 4, 2018 Category: Biomedical Science Authors: George A. Kanakis, Eberhard Nieschlag Source Type: research

Klinefelter syndrome: more than hypogonadism
Klinefelter syndrome (KS) is the most frequent chromosome disorder in males (1:650 newborn males), defined by 47,XXY karyotype. The classical phenotype is that of a tall male with relatively long legs, small, firm testes and gynecomastia. Azoospermia and infertility are almost inevitably present, but may be overcome by TESE and ICSI. Nevertheless, a broad spectrum of phenotypes has been described and more than 70% of the actually existing KS men may remain undiagnosed throughout their lifespan. Accordingly, hypogonadism is usually not evident until early adulthood and progresses with ageing. (Source: Metabolism - Clinical and Experimental)
Source: Metabolism - Clinical and Experimental - February 4, 2018 Category: Biomedical Science Authors: George A. Kanakis, Eberhard Nieschlag Source Type: research

Changing practices: The addition of a novel surgical approach to gynecomastia
Gynecomastia can be a significant impediment to quality of life for men who suffer from this affliction. Numerous surgical techniques have been described in the literature ranging from minimally invasive options such as liposuction to incision based reductions. The standard for the general surgeons at our institution has been subcutaneous mastectomy through a circumareolar incision, which often proved inadequate for patients with grade II or III gynecomastia. In November 2013 we adopted a new technique, the “double donut”, that offers the post-operative appearance of a limited incision, with the additional bene...
Source: American Journal of Surgery - February 3, 2018 Category: Surgery Authors: D.L. Wyrick, M. Roberts, Z.T. Young, A.T. Mancino Source Type: research

Changing practices: the addition of a novel surgical approach to gynecomastia
Gynecomastia can be a significant impediment to quality of life for men who suffer from this affliction. Numerous surgical techniques have been described in the literature ranging from minimally invasive options such as liposuction to incision based reductions. The standard for the general surgeons at our institution has been subcutaneous mastectomy through a circumareolar incision, which often proved inadequate for patients with grade II or III gynecomastia. In November 2013 we adopted a new technique, the “double donut”, that offers the post-operative appearance of a limited incision, with the additional bene...
Source: American Journal of Surgery - February 3, 2018 Category: Surgery Authors: D.L. Wyrick, M. Roberts, Z.T. Young, A.T. Mancino Source Type: research

Finasteride topical delivery systems for androgenetic alopecia.
This study will serve as a future perspective regarding topical delivery of finasteride. The literature analysis has exhibited that most of the previous investigators have used propylene glycol in their finasteride-loaded topical formulations, while poloxamer P407, monoolein, transcutol P and choline was used in few formulations. Moreover among all drug delivery systems, finasteride liposomal gel system consisting of 2% methyl cellulose and gel system containing poloxamer P407 exhibited the highest flux with a value of 28.4 ± 1.3 µg/cm2h and 23.1 ± 1.4 µg/cm2h, respectively. Several topical drug d...
Source: Current Drug Delivery - January 23, 2018 Category: Drugs & Pharmacology Authors: Khan MZU, Khan SA, Ubaid M, Shah A, Kousar R, Murtaza G Tags: Curr Drug Deliv Source Type: research

The Impact of Idiopathic Gynecomastia on Lives of Young Men Prior to Surgical Reduction
Purpose: Idiopathic gynecomastia (IGM) has received little attention in the adolescent and emerging adult literature; however, anecdotal evidence has shown that many young men suffer in silence, trying a variety of commercial products that do little or no good. The purpose of this qualitative descriptive analysis was to identify psychosocial factors reported by young men seeking surgical correction of IGM. (Source: Journal of Adolescent Health)
Source: Journal of Adolescent Health - January 17, 2018 Category: Child Development Authors: Lynn Rew, Cara Young Source Type: research

Re: Gynecomastia Surgery—Impact on Life QualityA Prospective Case-Control Study
No abstract available (Source: Annals of Plastic Surgery)
Source: Annals of Plastic Surgery - January 17, 2018 Category: Cosmetic Surgery Tags: Letters and Commentary Source Type: research

Next Generation Sequencing expression profiling of mitochondrial subunits in men with Klinefelter syndrome.
Conclusion: It is known that defects of the mtDNA encoding mitochondrial subunits are responsible for the malfunction of Complex I, which will eventually lead to the Complex I deficiency, the most common respiratory chain defect in human disorders. Since it has been shown that decreased Complex I protein levels could induce apoptosis, wehypothesizethat the above-mentioned MT-ND6 down-expression contributes to the wide range of phenotypes observed in men with KS. PMID: 29333085 [PubMed - in process] (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - January 17, 2018 Category: Biomedical Science Tags: Int J Med Sci Source Type: research

Re: Gynecomastia Surgery—Impact on Life QualityA Prospective Case-Control Study
No abstract available (Source: Annals of Plastic Surgery)
Source: Annals of Plastic Surgery - January 12, 2018 Category: Cosmetic Surgery Tags: Letters and Commentary Source Type: research

Quantitative CT Assessment of Gynecomastia in the General Population and in Dialysis, Cirrhotic, and Obese Patients
Conclusions Breast tissue diameter is a simple and reliable quantitative tool for the assessment of gynecomastia. This method provides the ability to determine the incidence of gynecomastia by age in the general population. Radiological gynecomastia should be defined as 22 mm, 28 mm, or 36 mm (90th, 95th, and 97.5th percentiles, respectively). Radiological gynecomastia is not associated with obesity, but is associated with cirrhosis and dialysis. (Source: Academic Radiology)
Source: Academic Radiology - January 8, 2018 Category: Radiology Source Type: research

Daily subcutaneous testosterone for management of testosterone deficiency.
Authors: Yazdani N, Matthews Branch S Abstract Testosterone deficiency (TD) is a public health concern, a predictor of metabolic syndrome, and is associated with an increased all-cause and cardiovascular mortality. Testosterone deficiency in men is treated by a variety of methods including injectable testosterone compounds, patches, gels, pellets, and oral preparations. The use of testosterone alone has been linked to various adverse effects including, infertility, testicular atrophy, erythropoiesis, and gynecomastia. To determine the effectiveness of therapy using the Daily Subcutaneous Testosterone (DST) method i...
Source: Frontiers in Bioscience - Elite - January 5, 2018 Category: Biomedical Science Tags: Front Biosci (Elite Ed) Source Type: research

Closed-Suction Drains After Subcutaneous Mastectomy for Gynecomastia: Do they Reduce Complications?
(Source: Aesthetic Plastic Surgery)
Source: Aesthetic Plastic Surgery - January 4, 2018 Category: Cosmetic Surgery Source Type: research

[A POEMS syndrome revealed by a blue toe syndrome].
CONCLUSION: This is to our knowledge the first case of thrombotic microangiopathy in POEMS syndrome without embolic cause or calciphylaxis. PMID: 29288001 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - January 1, 2018 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

The unusual suspects: A review of unusual benign and malignant male breast imaging cases
Male breast disease is uncommon. Men presenting with breast symptoms may represent unique diagnostic challenges for the radiologist, particularly if imaging findings are not classic for gynecomastia or carcinoma. In this paper we review 10 unusual male breast cases, 5 benign and 5 malignant, including the radiologic findings, differential diagnosis, pathology and management. (Source: Clinical Imaging)
Source: Clinical Imaging - December 28, 2017 Category: Radiology Authors: Victoria L. Mango, Sarah Goodman, Kim Clarkin, Ralph T. Wynn, Lauren Friedlander, Hanina Hibshoosh, Richard Ha Source Type: research

Closed-Suction Drains After Subcutaneous Mastectomy for Gynecomastia: Do They Reduce Complications? A Different Approach
ConclusionOur technique presents a lot of advantages, reduced length of stay in the hospital, costs from drain site care and clinic visits, patients ’ discomfort, and antibiotic prescriptions.Level of Evidence VThis journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authorswww.springer.com/00266. (Source: Aesthetic Plastic Surgery)
Source: Aesthetic Plastic Surgery - December 20, 2017 Category: Cosmetic Surgery Source Type: research

Hormonal treatment and quality of life of prostate cancer patients: new evidences.
Authors: Tucci M, Leone G, Buttigliero C, Zichi C, DI Stefano RF, Pignataro D, Vignani F, Scagliotti GV, DI Maio M Abstract Androgen deprivation therapy (ADT) is the mainstay of treatment of patients with relapsed or metastatic hormone-sensitive prostatic carcinoma. The dramatic reduction of serum testosterone levels induced by ADT produces multiple side effects as vasomotor flushing, sexual dysfunction, fatigue, impairment of cognitive function, reduced quality of sleep, gynecomastia and anemia, that are able to decrease health-related quality of life (QoL). In addition, hormonal therapy can interfere with bone me...
Source: Minerva Urologica e Nefrologica - December 17, 2017 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research

A journey through liposuction and liposculture: Review
Conclusion Liposuction is a safe, simple and effective method of body contouring. It has enormous potential for its application in ablative and reconstructive surgery, far from the most common aesthetic processes with a very low complication rate. (Source: Annals of Medicine and Surgery)
Source: Annals of Medicine and Surgery - December 16, 2017 Category: General Medicine Source Type: research

Testicular Estrogen-Secreting Leydig Cell Tumor in 18F-FDG PET/CT: An Incidental Detection in a Patient Treated by Chemotherapy for Hodgkin Lymphoma
This report highlights that a focal 18F-FDG uptake in the testicular region with unexplained gynecomastia should suggest the diagnosis of an estrogen-secreting Leydig cell tumor on 18F-FDG PET/CT. (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - December 8, 2017 Category: Nuclear Medicine Tags: Interesting Images Source Type: research

How to manage pseudoangiomatous stromal hyperplasia: our clinical experience
Conclusion: Imaging findings of PASH are nonspecific. It is difficult to give a true prognostic diagnosis through pathological evaluation of big masses with core needle biopsy. We recommend surgical excision, especially for big lesions with suspicious features. PMID: 29151311 [PubMed] (Source: Turkish Journal of Medical Sciences)
Source: Turkish Journal of Medical Sciences - November 22, 2017 Category: General Medicine Tags: Turk J Med Sci Source Type: research

Patient-reported outcome measures following gynecomastia correction: a systematic review
ConclusionsThe rate of patient satisfaction was high, although most studies did not use validated or quantifiable evaluation methods for assessment of satisfaction. A new self-assessment tool, which should include functional, psycho-relational, and cosmetic components, is needed to measure satisfaction and quality of life in patients who have undergone gynecomastia correction.Level of Evidence:  Level III, therapeutic study (Source: European Journal of Plastic Surgery)
Source: European Journal of Plastic Surgery - November 17, 2017 Category: Cosmetic Surgery Source Type: research

Perioral and tongue fasciculations in Kennedy ’s disease
We report the case of a 54-year-old right-handed man who presented with a 2-year history of progressive upper-limb weakness with mild dysarthria and prominent involuntary perioral abnormal movements that were characterized as fasciculations. Electromyography disclosed motor neuron disease. The diagnosis of Kennedy ’s disease was established by polymerase chain reaction. Perioral abnormal movements and fasciculations may represent important clinical clues to the diagnosis of Kennedy’s disease, particularly when associated with proximal muscle atrophy and gynecomastia. In suspected cases, genetic testing fo r ele...
Source: Neurological Sciences - November 4, 2017 Category: Neurology Source Type: research

Ultrasonographic assessment of male breast diseases
Abstract Although rare and accounting for less than 1% of all breast cancers, the incidence of breast cancer in men has increased by 26% over the past few decades. Very little has been reported on the sonographic appearance of benign and malignant male breast conditions. The aim of this study was to describe the ultrasonographic features of male breast disease and the value of ultrasound in the evaluation of male breast disease. Between December 2006 and October 2014, ultrasound examinations were performed in 560 male patients presenting with enlargement of, pain in, and/or a lump in the breast. One hundred and thirty‐si...
Source: The Breast Journal - November 1, 2017 Category: Cancer & Oncology Authors: Xueyu Rong, Qiang Zhu, Wenxiu Jia, Teng Ma, Xixi Wang, Ning Guo, Hongtao Ji Tags: ORIGINAL ARTICLE Source Type: research

Comment to: “Complications and Outcomes After Gynecomastia Surgery: Analysis of 204 Pediatric and 1583 Adult Cases from a National Multi-center Database”
(Source: Aesthetic Plastic Surgery)
Source: Aesthetic Plastic Surgery - October 26, 2017 Category: Cosmetic Surgery Source Type: research

Comment to: “Complications and Outcomes After Gynecomastia Surgery: Analysis of 204 Pediatric and 1583 Adult Cases from a National Multi-center Database”
Level of Evidence V This journal requires that authors assign a level of evidence to each article. For a full description of these evidence-based medicine ratings, please refer to the Table of Contents or the online Instructions to Authorswww.springer.com/00266. (Source: Aesthetic Plastic Surgery)
Source: Aesthetic Plastic Surgery - October 26, 2017 Category: Cosmetic Surgery Source Type: research

Multiparameter Investigation of a 46,XX/46,XY Tetragametic Chimeric Phenotypical Male Patient with Bilateral Scrotal Ovotestes and Ovulatory Activity
We report on an adult male initially presenting with gynecomastia and a painless scrotal mass without additional genital anomalies. Hyperpigmentation of the skin following the Blaschko's lines was identified. He underwent gonadectomy because of suspected cancer. Histological analyses revealed an ovotestis with ovulatory activity confirmed by immunohistochemistry with multiple markers. Karyotyping of cultured peripheral blood lymphocytes and a buccal smear revealed a 46,XX/46,XY chimeric constitution with different percentages. Multiple molecular analyses as well as blood typing implied a tetragametic origin. After the unil...
Source: Sexual Development - October 25, 2017 Category: Biology Source Type: research

Breast diseases in children: the spectrum of radiologic findings in a cohort study.
CONCLUSION: In our study, the most common referral reason to radiology was a palpable breast mass. Neonatal hypertrophy and early breast development in younger children, and developmental abnormalities in older children may be kept in mind as the most common radiologic findings. Our study confirms the substantial absence of malignancies in children as well as a widely different disease spectrum in comparison with the adult population. PMID: 29033391 [PubMed - as supplied by publisher] (Source: Diagnostic and Interventional Radiology : The Turkish Society of Radiology)
Source: Diagnostic and Interventional Radiology : The Turkish Society of Radiology - October 16, 2017 Category: Radiology Authors: Durmaz E, Öztek MA, Arıöz Habibi H, Kesimal U, Sindel HT Tags: Diagn Interv Radiol Source Type: research

Reply: Gynecomastia Classification for Surgical Management A Systematic Review and Novel Classification System
No abstract available (Source: Plastic and Reconstructive Surgery)
Source: Plastic and Reconstructive Surgery - October 1, 2017 Category: Cosmetic Surgery Tags: Letters Source Type: research

Translation And Cultural Adaptation Of The Body-Q Chest Module Into Finnish For Use In Gynecomastia, Weight Loss And FTM Chest Surgery
The BODY-Q is a patient-reported outcome (PRO) instrument developed for weight loss and/or body contouring that measures appearance, health-related quality of life and experience of care. The aim of this study was to translate and culturally adapt a new module of the BODY-Q for chest surgery into Finnish and to establish a local branch for data collection for the international field-test. (Source: Value in Health)
Source: Value in Health - October 1, 2017 Category: International Medicine & Public Health Authors: JP Repo, A Klassen, P Homsy, A Lindford, P Popov Source Type: research

Testosterone Therapy: Review of Clinical Applications.
Abstract Testosterone therapy is increasingly common in the United States, and many of these prescriptions are written by primary care physicians. There is conflicting evidence on the benefit of male testosterone therapy for age-related declines in testosterone. Physicians should not measure testosterone levels unless a patient has signs and symptoms of hypogonadism, such as loss of body hair, sexual dysfunction, hot flashes, or gynecomastia. Depressed mood, fatigue, decreased strength, and a decreased sense of vitality are less specific to male hypogonadism. Testosterone therapy should be initiated only after two...
Source: American Family Physician - October 1, 2017 Category: Primary Care Authors: Petering RC, Brooks NA Tags: Am Fam Physician Source Type: research

Gynecomastia Classification for Surgical Management: A Systematic Review and Novel Classification System
No abstract available (Source: Plastic and Reconstructive Surgery)
Source: Plastic and Reconstructive Surgery - September 29, 2017 Category: Cosmetic Surgery Tags: Letters Source Type: research

Reply: Gynecomastia Classification for Surgical Management: A Systematic Review and Novel Classification System
No abstract available (Source: Plastic and Reconstructive Surgery)
Source: Plastic and Reconstructive Surgery - September 29, 2017 Category: Cosmetic Surgery Tags: Letters Source Type: research

Multiparameter Investigation of a 46,XX/46,XY Tetragametic Chimeric Phenotypical Male Patient with Bilateral Scrotal Ovotestes and Ovulatory Activity.
We report on an adult male initially presenting with gynecomastia and a painless scrotal mass without additional genital anomalies. Hyperpigmentation of the skin following the Blaschko's lines was identified. He underwent gonadectomy because of suspected cancer. Histological analyses revealed an ovotestis with ovulatory activity confirmed by immunohistochemistry with multiple markers. Karyotyping of cultured peripheral blood lymphocytes and a buccal smear revealed a 46,XX/46,XY chimeric constitution with different percentages. Multiple molecular analyses as well as blood typing implied a tetragametic origin. After the unil...
Source: Sexual Development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation - September 20, 2017 Category: Genetics & Stem Cells Authors: van Bever Y, Wolffenbuttel KP, Brüggenwirth HT, Blom E, de Klein A, Eussen BHJ, van der Windt F, Hannema SE, Dessens AB, Dorssers LCJ, Biermann K, Hersmus R, de Rijke YB, Looijenga LHJ Tags: Sex Dev Source Type: research

Multiparameter Investigation of a 46,XX/46,XY Tetragametic Chimeric Phenotypical Male Patient with Bilateral Scrotal Ovotestes and Ovulatory Activity
We report on an adult male initially presenting with gynecomastia and a painless scrotal mass without additional genital anomalies. Hyperpigmentation of the skin following the Blaschko's lines was identified. He underwent gonadectomy because of suspected cancer. Histological analyses revealed an ovotestis with ovulatory activity confirmed by immunohistochemistry with multiple markers. Karyotyping of cultured peripheral blood lymphocytes and a buccal smear revealed a 46,XX/46,XY chimeric constitution with different percentages. Multiple molecular analyses as well as blood typing implied a tetragametic origin. After the unil...
Source: Sexual Development - September 19, 2017 Category: Biology Source Type: research

Gynecomastia: histological appearance in different age groups.
CONCLUSIONS: Fibrous gynecomastia was found to be more common in adolescents and young adults, while the florid type was more frequent in older patients. Patients presenting with florid gynecomastia showed a higher rate of recurrence than patients with the fibrous type of gynecomastia. PMID: 28876176 [PubMed - as supplied by publisher] (Source: Journal of Plastic Surgery and Hand Surgery)
Source: Journal of Plastic Surgery and Hand Surgery - September 7, 2017 Category: Surgery Tags: J Plast Surg Hand Surg Source Type: research

Low zinc levels may contribute to gynecomastia in puberty
This study aimed to determine whether there were any differences in trace element levels between adolescent boys with gynecomastia and control boys and to determine the correlations between the levels of trace elements and body mass index (BMI) and sex hormones. The pubertal gynecomastia group comprised of 41 patients (mean age=13.2 ±0.9 years), who were admitted to Hacettepe University İhsan Doğramacı Children’s Hospital in Ankara. Control group comprised of 21 healthy male children. Analyses of trace element levels were performed atomic absorption spectrometry. The mean zinc level of control group was 101...
Source: Journal of Trace Elements in Medicine and Biology - September 3, 2017 Category: Biochemistry Source Type: research

Closed-Suction Drains After Subcutaneous Mastectomy for Gynecomastia: Do They Reduce Complications?
ConclusionsClosed-suction drains may reduce rates of clinically significant seromas requiring needle aspiration. Though drains carry their own pertinent adverse effects (e.g., patient discomfort and anxiety, cost, and additional clinic visits), there remains no universal standard of care and surgeon practices vary widely. Given the potential to reduce seroma rates, we recommend that surgeons consider placing drains and discuss with patients the benefits and risks of drains after surgical treatment of gynecomastia.Level of Evidence IVThis journal requires that authors assign a level of evidence to each article. For a full d...
Source: Aesthetic Plastic Surgery - August 25, 2017 Category: Cosmetic Surgery Source Type: research

Management of Adolescent Gynecomastia: An Update.
Abstract Gynecomastia refers to an enlargement of the male breast caused by benign proliferation of the glands ducts and stromal components including fat. It is the most common form of breast swelling seen in adolescent males. During pubertal development, gynecomastia can develop as a result of transient relative imbalances between androgens and estrogens. Pubertal gynecomastia is self-limited in 75 to 90% of adolescents and regresses over 1 to 3 years. However it may cause significant psychological stress and depression in adolescents. For boys with persistent gynecomastia that is causing substantial tenderness o...
Source: Acta Bio-Medica : Atenei Parmensis - August 23, 2017 Category: General Medicine Authors: Soliman AT, De Sanctis V, Yassin M Tags: Acta Biomed Source Type: research

Delayed Diagnosis of Acromegaly in the Context of Post-Traumatic Stress Disorder due to Symptoms Mimicking Known Psychotropic Medication Side Effects.
CONCLUSION: This case shows that side effects of medications can easily mimic some medical conditions. The possibility of unrecognized disease should not be overlooked simply because a patient's symptoms that develop after starting a medication correspond well the side effect profile of the prescribed medications. This is especially true if side effects do not stop with alteration of medication dose, cessation of the medication, or changing to another medication. Pituitary adenomas are rare in patients treated for PTSD. However, attribution of PTSD patient's symptoms to the side effects of selective serotonin reuptake inhi...
Source: Military Medicine - August 17, 2017 Category: International Medicine & Public Health Tags: Mil Med Source Type: research

Feminizing Adrenocortical Carcinoma Without Gynecomastia.
Authors: Chentli F, Chabour F, Bouchibane D, Nouar N Abstract Malignant feminizing adrenocortical tumors are exceedingly rare. Their main presentation is gynecomastia. In these estrogen secreting tumors (with or without other adrenocortical hormones) lack of gynecomastia is exceptional as in our case. A 44-year-old man presented with abdominal pain. Radiological assessment revealed a tumor measuring 120 × 95 mm in the retroperitoneal area with numerous metastases. Pathological examination pleaded for an adrenal origin with a Weiss's score of 5. Six months later, the tumor relapsed, and he had a second surgery...
Source: Oman Medical Journal - August 16, 2017 Category: Middle East Health Tags: Oman Med J Source Type: research

Orange Peel Excision of Gland: A Novel Surgical Technique for Treatment of Gynecomastia
No abstract available (Source: Annals of Plastic Surgery)
Source: Annals of Plastic Surgery - August 11, 2017 Category: Cosmetic Surgery Tags: Letters and Commentary Source Type: research

False Positive Uptake in Bilateral Gynecomastia on 68Ga-PSMA PET/CT Scan
Abstract: A 66-year-old man on hormonal therapy with prostate cancer was referred for 68Ga-PSMA PET/CT scan for biochemical recurrence. 68Ga-PSMA PET/CT scan detected moderate heterogeneous tracer concentration in bilateral breast parenchyma, in addition to the abnormal tracer concentration in enlarged prostate gland, right external iliac lymph node, and sclerotic lesion in L4 vertebra. On clinical examination, he was found to have bilateral gynecomastia. Abnormal concentration of 68Ga-PSMA in breast cancer is now well known, and in this context, it is important to know that tracer localization can occur in gynecomastia as...
Source: Clinical Nuclear Medicine - August 7, 2017 Category: Nuclear Medicine Tags: Interesting Images Source Type: research

Gynecomastia: glandular-liposculpture through a single transaxillary one hole incision.
Authors: Lee YK, Lee JH, Kang SY Abstract Gynecomastia is characterized by the benign proliferation of breast tissue in men. Herein, we present a new method for the treatment of gynecomastia, using ultrasound-assisted liposuction with both conventional and reverse-cutting edge tip cannulas in combination with a pull-through lipectomy technique with pituitary forceps through a single transaxillary incision. Thirty patients were treated with this technique at the author's institution from January 2010 to January 2015. Ten patients were treated with conventional surgical excision of the glandular/fibrous breast tissue...
Source: Journal of Plastic Surgery and Hand Surgery - August 1, 2017 Category: Surgery Tags: J Plast Surg Hand Surg Source Type: research

Adverse effects of androgen deprivation therapy in patients with prostate cancer: focus on metabolic complications.
Authors: Tzortzis V, Samarinas M, Zachos I, Oeconomou A, Pisters LL, Bargiota A Abstract Prostate cancer is the most common cancer among men and androgen deprivation therapy (ADT) is the most effective treatment for this disease. The cornerstone of the treatment of prostate cancer is inhibition of testosterone production which interrupts testosterone-induced growth of the prostate tumor. The dramatic decrease in testosterone levels, however, has several undesirable effects on the metabolic profile and bone metabolism and can also lead to fatigue, loss of libido, gynecomastia, and anemia, provoke vasomotor flushing,...
Source: Hormones - July 27, 2017 Category: Endocrinology Tags: Hormones (Athens) Source Type: research

Optimal Positioning of the Nipple –Areola Complex in Men Using the Mohrenheim-Estimated-Tangential-Tracking-Line (METT-Line): An Intuitive Approach
In this study, a statistically significant deviation was seen in almost all dimensions, although the clinical relevance cannot be conclusively assessed. We found a positional relationship of the NAC to the infraclavicular groove ( “Mohrenheim pit”) in the vertical and 4–4.5 cm above the submammary fold. The position of the NAC can be satisfactorily determined by a combination of plastic surgical intuition, patient wishes and practical metric methods using the Mohrenheim-Estimated-Tangential-Tracking-Line (METT-Line).Level of Evidence VThis journal requires that authors assign a level of evidence to e...
Source: Aesthetic Plastic Surgery - July 19, 2017 Category: Cosmetic Surgery Source Type: research

A Systematic Review and Framework for the Use of Hormone Therapy with Salvage Radiation Therapy for Recurrent Prostate Cancer
Conclusions Similar to the selective use of HT with radiotherapy in localized prostate cancer, not all patients appear to derive a meaningful benefit from HT with SRT. Patient, tumor, and treatment factors must be considered when recommending the use of HT with SRT. Knowledge gaps exist in the level 1 data regarding the optimal duration and type of HT, as well as the ability to use predictive biomarkers to personalize the use of HT with SRT. Important clinical trials (RADICALS and NRG GU-006) are aimed to answer these questions. Patient summary In this report, we performed a systematic review of the literature to determine...
Source: European Urology - July 15, 2017 Category: Urology & Nephrology Source Type: research

Reduction of the Areolar Diameter After Ultrasound-Assisted Liposuction for Gynecomastia
Conclusions: In cases of gynecomastia, the removal of the glandular and fatty tissue underneath the areola releases the expanding forces and pressure that enlarge it. In many cases of gynecomastia, UAL alone is effective in reducing the size of the NAC and allows the surgeon to avoid placing scars on the breast. (Source: Annals of Plastic Surgery)
Source: Annals of Plastic Surgery - July 12, 2017 Category: Cosmetic Surgery Tags: Breast Surgery Source Type: research

Management of Gynecomastia in Patients With Different Body Types: Considerations on 312 Consecutive Treated Cases
No abstract available (Source: Annals of Plastic Surgery)
Source: Annals of Plastic Surgery - July 12, 2017 Category: Cosmetic Surgery Tags: Letters and Invited Commentary Source Type: research

Reply to the Comment on: Management of Gynecomastia in Patients With Different Body Types: Considerations on 312 Consecutive Treated Cases
No abstract available (Source: Annals of Plastic Surgery)
Source: Annals of Plastic Surgery - July 12, 2017 Category: Cosmetic Surgery Tags: Letters and Invited Commentary Source Type: research

Discussion: The Characteristics and Short-Term Surgical Outcomes of Adolescent Gynecomastia by B.S. Choi et al.
(Source: Aesthetic Plastic Surgery)
Source: Aesthetic Plastic Surgery - June 21, 2017 Category: Cosmetic Surgery Source Type: research