Gynecomastia: a common indication for mammography in men of all age.
CONCLUSIONS: The evaluation of GM can be complex but a stepwise approach that starts with careful history taking and physical examination may obviate the need for extensive work-up. In this context, MX has been shown to be an accurate diagnostic tool for detecting GM and should be the first imaging examination to be performed in all clinically suspicious lesions referred for imaging. PMID: 27467870 [PubMed - as supplied by publisher] (Source: Acta Bio-Medica : Atenei Parmensis)
Source: Acta Bio-Medica : Atenei Parmensis - July 29, 2016 Category: Journals (General) Authors: Capasso R, Sica A, D'Amora M, Mostardi M, Martella I, Totaro M, Della Casa G, Vallara M, Pesce A, Gatta G, Cappabianca S Tags: Acta Biomed Source Type: research

Sociodemographic and clinical characteristics of candidates for liver transplantation
Resumo Objetivo Com o prop ósito de gerar evidências que contribuam para a prática clínica do enfermeiro na implementação de intervenções direcionadas para a melhoria do cuidado, o presente estudo teve como objetivo analisar dados sociodemográficos e clínicos de candidatos ao transplante de fígado. Métodos Estud o transversal, prospectivo, conduzido em hospital terciário do interior paulista. No início da coleta de dados, 77 pacientes estavam registrados na lista de espera, entretanto o cadastro é dinâmico. Assim, ...
Source: Acta Paulista de Enfermagem - July 22, 2016 Category: Nursing Source Type: research

Hyperprolactinemia Secondary to Pituitary Microadenoma versus Haloperidol-A Diagnostic Enigma: A Case Report and Brief Review.
CONCLUSION: Diagnosis and etiology of hyperprolactinemia were complicated by the minimal nature of clinical symptoms, the type of antipsychotic agent and the prolactin level. The MRI facilitated the diagnosis of pituitary microadenoma and further treatment option with bromocriptine. MRI of the pituitary is indicated for patients with hyperprolactinemia where the etiology is not clearly due to medication. PMID: 27440143 [PubMed - as supplied by publisher] (Source: Current Drug Safety)
Source: Current Drug Safety - July 19, 2016 Category: Drugs & Pharmacology Authors: Madhusoodanan S, Steinberg LR, Coleman A, Bavli S Tags: Curr Drug Saf Source Type: research

The Long Term Outcome Of Boys With Partial Androgen Insensitivity Syndrome And A Mutation In The Androgen Receptor Gene.
CONCLUSIONS: Boys with genetically confirmed PAIS are likely to have a poorer clinical outcome than those with XY DSD, normal testosterone synthesis and without an identifiable AR mutation. Routine genetic analysis of AR to confirm PAIS informs long-term prognosis and management. PMID: 27403927 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - July 12, 2016 Category: Endocrinology Authors: Lucas-Herald A, Bertelloni S, Juul A, Bryce J, Jiang J, Rodie M, Sinnott R, Boroujerdi M, Lindhardt-Johansen M, Hiort O, Holterhus PM, Cools M, Guaragna-Filho G, Guerra-Junior G, Weintrob N, Hannema S, Drop S, Guran T, Darendeliler F, Nordenstrom A, Hughe Tags: J Clin Endocrinol Metab Source Type: research

Johnson & Johnson is ordered to pay $70m to boy who developed gynecomastia
(Source: BMJ News)
Source: BMJ News - July 11, 2016 Category: Journals (General) Source Type: research

Inherited Xq13.2-q21.31 duplication in a boy with recurrent seizures and pubertal gynecomastia: Clinical, chromosomal and aCGH characterization
We report on a 16-year-old boy with a maternally inherited ~18.3 Mb Xq13.2-q21.31 duplication delimited by aCGH. As previously described in patients with similar duplications, his clinical features included intellectual disability, developmental delay, speech delay, generalized hypotonia, infantile feeding difficulties, self-injurious behavior, short stature and endocrine problems. As additional findings, he presented recurrent seizures and pubertal gynecomastia. His mother was phenotypically normal and had completely skewed inactivation of the duplicated X chromosome, as most female carriers of such duplications. Five pre...
Source: Meta Gene - July 9, 2016 Category: Genetics & Stem Cells Source Type: research

Sertoli cell tumor arising in a cryptorchid testis presenting as a content of inguinal hernial sac.
Abstract Sertoli cell tumors (SCTs) are rare tumors accounting for
Source: Indian Journal of Pathology and Microbiology - July 1, 2016 Category: Pathology Authors: Venkatesh K, Hemalata M, Sathyavathi S, Kumar S Tags: Indian J Pathol Microbiol Source Type: research

Adrenal cortical carcinoma with tumor thrombus extension into the right atrium: A case report.
Authors: Wang Y, Zhou F, Pan H, Jin B Abstract Adrenal cortical carcinoma (ACC) is a rare aggressive malignant tumor associated with a poor prognosis. Patients with ACC usually present with abnormal hormone secretion, tumor growth or encroachment on the surrounding viscera. An early diagnosis of ACC is considered challenging. The present study reports a case of ACC with tumor thrombus extension into the inferior vena cava and right atrium. A 33-year-old male patient exhibited symptoms of gynecomastia and abdominal distention, which were due to the abnormal hormone secretion levels and to the presence of a large mas...
Source: Oncology Letters - June 19, 2016 Category: Cancer & Oncology Tags: Oncol Lett Source Type: research

46 XX karyotype during male fertility evaluation; case series and literature review.
Abstract Forty-six XX disorder of sex development is an uncommon medical condition observed at times during the evaluation of a man's fertility. The following is a case series and literature review of phenotypically normal men diagnosed with this karyotype. Our goal is to comprehend the patients' clinical presentation as well as their laboratory results aiming to explore options available for their management. A formal literature review through PubMed and MEDLINE databases was performed using "46 XX man" as a word search. A total of 55 patients, including those conveyed in this article were diagnosed wit...
Source: Asian Journal of Andrology - June 10, 2016 Category: Urology & Nephrology Authors: Majzoub A, Arafa M, Starks C, Elbardisi H, Al Said S, Sabanegh E Tags: Asian J Androl Source Type: research

Spectrum of the Breast Lesions With Increased 18F-FDG Uptake on PET/CT
Abstract: Interpretation of 18F-FDG PET/CT studies in breast is challenging owing to nonspecific FDG uptake in various benign and malignant conditions. Benign conditions include breast changes in pregnancy and lactation, gynecomastia, mastitis, fat necrosis, fibroadenoma, intraductal papilloma, and atypical ductal hyperplasia. Among malignancies, invasive ductal carcinoma and invasive lobular carcinoma are common histological types of breast carcinoma. Rarely, other unusual histological types of breast carcinomas (eg, intraductal papillary carcinoma, invasive micropapillary carcinoma, medullary carcinoma, mucinous carcinom...
Source: Clinical Nuclear Medicine - June 8, 2016 Category: Nuclear Medicine Tags: Atlas Article Source Type: research

The Safety and Efficacy of Mineralocorticoid Receptor Antagonists in Patients Who Require Dialysis: A Systematic Review and Meta-analysis
Conclusions Given the uncertainty of both the benefits and harms of MRAs in dialysis, large high-quality trials are required. (Source: American Journal of Kidney Diseases)
Source: American Journal of Kidney Diseases - June 4, 2016 Category: Urology & Nephrology Source Type: research

Gynecomastia Management: An Evolution and Refinement in Technique at UT Southwestern Medical Center
Source: Plastic and Reconstructive Surgery – Global Open - June 1, 2016 Category: Cosmetic Surgery Tags: Special Topic Source Type: research

Feminizing adrenal tumor in a 6-year-old boy
Publication date: Available online 30 May 2016 Source:Egyptian Pediatric Association Gazette Author(s): Hend M. Soliman, Mona Hafez, Gamal Eltagy, Ahmed Fares A 6-year-old boy presented with bilateral gynecomastia and breast tenderness. The condition started since 1year before medical consultation with gradual onset and progressive course of breast enlargement and accelerated growth with no history of any nipple discharge. There was no history of drug intake or chronic diseases. Investigations showed picture of pseudo precocious puberty with advanced bone age, suppressed LH, FSH and high estradiol (E2). Adrenal precu...
Source: Egyptian Pediatric Association Gazette - May 31, 2016 Category: Pediatrics Source Type: research

Bilateral Atypical Ductal Hyperplasia with Microcalcifications in a Patient with Gynecomastia.
Authors: Vidal P, Berner JE, Klenner A, Tapia Ó PMID: 27218035 [PubMed] (Source: Archives of Plastic Surgery)
Source: Archives of Plastic Surgery - May 28, 2016 Category: Cosmetic Surgery Tags: Arch Plast Surg Source Type: research

Radiation therapy for primary breast lymphoma in male gynecomastia: a rare case report and review of the literature.
Abstract Primary breast lymphoma is a rare type of non-Hodgkin lymphoma and usually affects women, although a few cases have been reported in men. Chemotherapy and radiation therapy, or a combination of both, are frequently administered for treatment of primary breast lymphoma, as local control by surgical resection is poor. No standard therapy has been established, and the optimal radiation dose and irradiation field for male patients are unknown. The present report describes a 75-year-old man with bilateral cirrhosis-induced gynecomastia who was diagnosed with primary breast lymphoma; specifically, diffuse large...
Source: International Journal of Hematology - May 25, 2016 Category: Hematology Authors: Ishibashi N, Hata M, Mochizuki T, Ogawa K, Sugiura H, Takekawa Y, Maebayashi T, Aizawa T, Sakaguchi M, Abe O Tags: Int J Hematol Source Type: research

Normal Distribution Pattern and Physiological Variants of Ga-68-PSMA PET/CT
Conclusions This study demonstrates normal distribution pattern, range of SUVs and physiological variants of Ga-68-PSMA. Additionally, several potential pitfalls were documented. (Source: Journal of Nuclear Medicine)
Source: Journal of Nuclear Medicine - May 24, 2016 Category: Nuclear Medicine Authors: Demirci, E., Sahin, O. E., Ocak, M., Akovali, B., Kabasakal, L. Tags: SPECIAL MTA: Novel Nonradioactive Probes Posters Source Type: research

Sexual function and hormone profile in young adult men with idiopathic gynecomastia: Comparison with healthy controls.
Authors: Sir E, Üçer O, Aksoy A, Güngör M, Ceylan Y Abstract OBJECTIVES: To compare sexual function and hormone profile in male patients with gynecomastia with matched controls. MATERIALS-METHODS: Forty-seven male subjects with gynecomastia and thirty healthy controls were enrolled in this study. Serum free T3, free T4, TSH, FSH, prolactin, estradiol, total testosterone, free testosterone, DHEA-SO4, LH and total PSA were measured in the patients and controls. Sexual function of the patients and controls were evaluated using International Index of Erectile Function (IIEF). The hormone value...
Source: Breast Disease - May 17, 2016 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Severe Gynecomastia: New Technique Using Superior Pedicle NAC Flap Through a Circumareolar Approach
Conclusions: A new periareolar approach for correction of severe-grade gynecomastia permits broad resection of excess skin and submammary tissue while avoiding unattractive scars on the patient’s chest. (Source: Annals of Plastic Surgery)
Source: Annals of Plastic Surgery - May 17, 2016 Category: Cosmetic Surgery Tags: Breast Surgery Source Type: research

Post-traumatic onset of secondary progression of gynecomastia
Abstract Gynecomastia is a benign enlargement of the male breast which can be a source of significant anxiety and embarrassment for the patients. A great variety of etiologic factors have been investigated and discussed. However, only few studies in the literature have accentuated on the possible role of the chronic tissue trauma for the de novo development of gynecomastia. Nevertheless, the exact mechanism of its onset in such cases remains unclear. The authors report on a case of posttraumatic unilateral progression of preexisting stable gynecomastia. The possible role of a single episode of acute trauma as a tr...
Source: European Journal of Plastic Surgery - May 10, 2016 Category: Cosmetic Surgery Source Type: research

Tamoxifen in men: a review of adverse events
Summary Tamoxifen is an off‐label option to treat men for breast cancer, infertility, and idiopathic gynecomastia. Lately, tamoxifen has been proposed as a treatment to prevent gynecomastia in prostate cancer patients receiving antiandrogen therapy. We reviewed the adverse events (AEs) reported in studies of men prescribed tamoxifen for these conditions to better understand its side‐effect profile. We searched PubMed for randomized controlled trials (RCTs) that included safety data of tamoxifen treatment in men with prostate cancer, breast cancer, infertility, and idiopathic gynecomastia. Non‐RCTs were also reviewed....
Source: Andrology - May 6, 2016 Category: Urology & Nephrology Authors: E. Wibowo, P. A. Pollock, N. Hollis, R. J. Wassersug Tags: Review Article Source Type: research

Spironolactone-induced bilateral gynecomastia in a man detected by SPECT myocardial perfusion imaging
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - May 5, 2016 Category: Nuclear Medicine Source Type: research

Cultural gynecomastia in the 21st century India: “Witch's milk” revisited
Publication date: Available online 4 May 2016 Source:Pediatria Polska Author(s): Devi Dayal, Vimlesh Soni, Dhaarani Jayaraman, Sindhuja Lakshminarasimhan, Naresh Sachdeva To determine the clinical course of gynecomastia–galactorrhea resulting from the common cultural practice of expressing breast milk in neonates. Despite the common cultural practice of expressing breast milk in neonates, the resulting gynecomastia is rarely reported probably because it is considered benign and short lasting. We performed a retrospective analysis of data of 20 infants (14 girls) diagnosed as cultural gynecomastia at a tertiary...
Source: Pediatria Polska - May 5, 2016 Category: Pediatrics Source Type: research

Gynecomastia and hormones
Abstract Gynecomastia—the enlargement of male breast tissue in men—is a common finding, frequently observed in newborns, adolescents, and old men. Physiological gynecomastia, occurring in almost 25 % of cases, is benign and self-limited; on the other hand, several conditions and drugs may induce proliferation of male breast tissue. True gynecomastia is a common feature often related to estrogen excess and/or androgen deficiency as a consequence of different endocrine disorders. Biochemical evaluation should be performed once physiological or iatrogenic gynecomastia has been ruled out. Non-endocrin...
Source: Endocrine - May 4, 2016 Category: Endocrinology Source Type: research

Comparison of Cellular Alterations in Fat Cells Harvested With Laser-Assisted Liposuction and Suction-Assisted Liposuction
Conclusion: The authors’ results have promising clinical relevance since mesenchymal stem cells harvested during LAL have maintained appropriate cellular features to be used for autologous fat transfer and fat grafting. (Source: Journal of Craniofacial Surgery)
Source: Journal of Craniofacial Surgery - May 1, 2016 Category: Surgery Tags: Original Articles Source Type: research

Atypical onset of bicalutamide-induced liver injury.
Abstract Anti-androgen therapy is the leading treatment for advanced prostate cancer and is commonly used for neoadjuvant or adjuvant treatment. Bicalutamide is a non-steroidal anti-androgen, used during the initiation of androgen deprivation therapy along with a luteinizing hormone-releasing hormone agonist to reduce the symptoms of tumor-related flares in patients with advanced prostate cancer. As side effects, bicalutamide can cause fatigue, gynecomastia, and decreased libido through competitive androgen receptor blockade. Additionally, although not as common, drug-induced liver injury has also been reported. H...
Source: World Journal of Gastroenterology : WJG - April 21, 2016 Category: Gastroenterology Authors: Yun GY, Kim SH, Kim SW, Joo JS, Kim JS, Lee ES, Lee BS, Kang SH, Moon HS, Sung JK, Lee HY, Kim KH Tags: World J Gastroenterol Source Type: research

Incremental Role of Mammography in the Evaluation of Gynecomastia in Men Who Have Undergone Chest CT
American Journal of Roentgenology, Ahead of Print. (Source: American Journal of Roentgenology)
Source: American Journal of Roentgenology - April 21, 2016 Category: Radiology Authors: Emily B. SonnenblickMary SalvatoreJanet SzaboKaren A. LeeLaurie R. Margolies Source Type: research

A Novel Mutation In Human Androgen Receptor Gene Causing Partial Androgen Insensitivity Syndrome In A Patient Presenting With Gynecomastia At Puberty.
CONCLUSION: The diagnosis of PAIS is based upon clinical phenotype and laboratory findings, and can be confirmed by detection of a defect in the AR gene. An accurate approach including a detailed family history suggesting an X-linked trait is an important clue to arrive at a quick diagnosis. PMID: 27087292 [PubMed - as supplied by publisher] (Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology)
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - April 19, 2016 Category: Endocrinology Tags: J Clin Res Pediatr Endocrinol Source Type: research

Prepubertal Gynecomastia Due to Indirect Exposure to Nonformulary Bioidentical Hormonal Replacement Therapy: A Case Report.
CONCLUSION: Indirect exposure to nonformulary hormonal replacement in our case report was an etiologic factor in the development of prepubertal gynecomastia. This novel estrogen exposure source has important implications in the differential diagnosis of prepubertal gynecomastia and potential adverse effects secondary to precocious hormonal exposure. PMID: 26995893 [PubMed - in process] (Source: Journal of Reproductive Medicine)
Source: Journal of Reproductive Medicine - March 22, 2016 Category: Reproduction Medicine Tags: J Reprod Med Source Type: research

The efficacy and safety of cold‐induced lipolysis in the treatment of pseudogynecomastia
ConclusionCold‐induced lipolysis is a safe, effective therapeutic option in the treatment of pseudogynecomastia. Lasers Surg. Med. © 2016 Wiley Periodicals, Inc. (Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - March 21, 2016 Category: Laser Surgery Authors: Jung Tae Park, Soon Hyo Kwon, Jung Won Shin, Kyoung Chan Park, Jung Im Na, Chang Hun Huh Tags: Clinical Report Source Type: research

The efficacy and safety of cold ‐induced lipolysis in the treatment of pseudogynecomastia
ConclusionCold‐induced lipolysis is a safe, effective therapeutic option in the treatment of pseudogynecomastia. Lasers Surg. Med. 48:584–589, 2016. © 2016 Wiley Periodicals, Inc. (Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - March 21, 2016 Category: Laser Surgery Authors: Jung Tae Park, Soon Hyo Kwon, Jung Won Shin, Kyoung Chan Park, Jung Im Na, Chang Hun Huh Tags: Clinical Report Source Type: research

Gynecomastia With Atypical Ductal Hyperplasia and Ductal Carcinoma In Situ Associated With Invasive Breast Carcinoma in a Male Patient on Antiretroviral Therapy: A Case Report
Breast carcinoma in males is rare although a 4-fold increased incidence is reported in HIV-infected men. Herein we report a case of invasive breast carcinoma in a HIV-positive man on antiretroviral therapy. The carcinoma was associated with features of florid gynecomastia, atypical ductal hyperplasia, ductal carcinoma in situ, and columnar cell change. This combination of morphological changes has not previously been reported in the context of male breast carcinoma and their etiopathological associations are discussed. (Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - March 2, 2016 Category: Pathology Authors: Coyne, J. D. Tags: Case Reports Source Type: research

LDOC1 Gene Expression in Men With Klinefelter Syndrome
Klinefelter syndrome (KS) results from an extra chromosome X, which is due to the failure of normal chromosomal segregation during meiosis. Patients with KS have gynecomastia, small testes, and azoospermia. Apoptosis is a mechanism responsible for the normal regulation of spermatogenesis. LDOC1 gene is a known regulator of nuclear factor mediated pathway to apoptosis through inhibition of nuclear factor kappa B (NF‐kappaB). Furthermore, the transcription factor myeloid zinc finger gene 1 (MZF‐1) has been shown to interact with LDOC1 and to enhance LDOC1 activity favoring apoptosis. We investigated the expression of LDO...
Source: Journal of Clinical Laboratory Analysis - March 1, 2016 Category: Laboratory Medicine Authors: Michele Salemi, Rosita A. Condorelli, Giusi Longo, Valentina Bullara, Carmelo Romano, Cristina Campagna, Paolo Bosco, Sandro Vignera, Aldo E. Calogero Tags: Research Article Source Type: research

[Anatomical study of men's nipple areola complex].
Abstract The surgical approach of gynecomastia, sexual reassignment surgery in female-to-male transsexuals and the increase of number of obese wishing to turn to plastic surgery led us to deepen the anatomical knowledge of the nipple areola complex (NAC) in men, poorly retailed in the literature. By inspiring us of the methodology of a Japanese study, we studied 50 healthy volunteers male, from 18 to 55 years old, from July till August 2015. We measured various distances relative to the NAC to define its vertical and horizontal position, as well as the internipple distance according to the size, to ...
Source: Annales de Chirurgie Plastique et Esthetique - February 23, 2016 Category: Cosmetic Surgery Authors: Vaucher R, Dast S, Assaf N, Sinna R Tags: Ann Chir Plast Esthet Source Type: research

A rapidly progressive defective spermatogenesis in a Mexican family affected by spino-bulbar muscular atrophy.
In this report we describe a Mexican family with three affected brothers with primary infertility caused by a progressive impairment of spermatogenesis leading to azoospermia before 40 years of age. They presented common features associated to patients affected by SMBA, such as gynecomastia, high level of CPK, muscle cramps, fasciculations, muscle wastage, and impaired swallowing. Two intracytoplasmic sperm injection (ICSI) cycles were performed in one of the patients resulting in fertilization failure. Molecular analysis of AR gene exon 1 revealed 54 CAG repeats in DNA extracted from leukocytes in affected patients and 22...
Source: Systems Biology in Reproductive Medicine - February 22, 2016 Category: Reproduction Medicine Authors: Piña-Aguilar RE, Regalado-Hernåndez MÁ, Moreno-García JD, Buentello-Volante B, Chacón-Camacho OF, Gallegos-Rivas MC, Kazakova E, Santillån-Hernåndez Y, Zenteno JC Tags: Syst Biol Reprod Med Source Type: research

Gynecomastia: A systematic review.
CONCLUSIONS: Several different surgical methods have been described with good results, minimal scars, and various levels of complications. Traditional surgical excision of glandular tissue combined with liposuction provides most consistent results and a low rate of complications. Pubertal gynecomastia may safely be managed by pharmacological anti-oestrogen treatment. PMID: 26051284 [PubMed - in process] (Source: Journal of Plastic Surgery and Hand Surgery)
Source: Journal of Plastic Surgery and Hand Surgery - February 18, 2016 Category: Surgery Tags: J Plast Surg Hand Surg Source Type: research

Enhancing Masculine Features After Massive Weight Loss
Conclusion Comprehensive excisional body contouring surgery of a central high tension abdominoplasty with a series of obliquely oriented ellipses throughout the torso appears to provide low risk improved body contour for the muscular male. Level of Evidence IV This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266. (Source: Aesthetic Plastic Surgery)
Source: Aesthetic Plastic Surgery - February 18, 2016 Category: Cosmetic Surgery Source Type: research

Mediastinal mixed germ cell tumor in an infertile male with Klinefelter syndrome:A case report and literature review
Dinesh Pradhan, Lileswar Kaman, Jasreman Dhillon, Sambit K MohantyJournal of Cancer Research and Therapeutics 2015 11(4):1034-1034 Klinefelter syndrome (KS) is a well-documented abnormality of the sex chromosome, with an incidence of 1 in 600 newborn males. It is characterized by a 47, XXY or a mosaic karyotype, hypergonadotrophic hypogonadism, infertility, reduced body hair, gynecomastia, and tall stature. Different neoplasms such as breast, testicular, and lymphoreticular malignancies may occur in 1% to2% of the cases with KS. Herein we describe a case of mediastinal mixed germ cell tumor (GCT) in a 40-year-old ...
Source: Journal of Cancer Research and Therapeutics - February 15, 2016 Category: Cancer & Oncology Authors: Dinesh PradhanLileswar KamanJasreman DhillonSambit K Mohanty Source Type: research

Hypospadias as a novel feature in spinal bulbar muscle atrophy
This study includes the first epidemiologic description of the co-occurrence of hypospadias and SBMA in subjects and their male relatives in Swedish population-based health registers, as well as an additional clinical case. One boy with severe hypospadias was screened for mutations in the AR gene and was found to have 42 CAG repeats in it, which is in the full range of mutations causing SBMA later in life. We also detected a maximum of four cases displaying the combination of SBMA and hypospadias in our national register databases. This is the third case report with hypospadias in association with CAG repeat expansions in ...
Source: Journal of Neurology - February 12, 2016 Category: Neurology Source Type: research

Plasma Kisspeptin Levels in Newborn Infants with Breast Enlargement.
CONCLUSION: The findings of this study suggest that plasma kisspeptin and serum prolactin levels may be involved in the physiopathology of breast enlargement in newborns. PMID: 26831552 [PubMed - in process] (Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology)
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - February 4, 2016 Category: Endocrinology Tags: J Clin Res Pediatr Endocrinol Source Type: research

Endocrine and molecular investigations in a cohort of 25 adolescent males with prominent/persistent pubertal gynecomastia
Summary Pubertal gynecomastia is a common condition observed in up to 65% of adolescent males. It is usually idiopathic and tends to regress within 1–2 years. In this descriptive cross‐sectional study, we investigated 25 adolescent males with prominent (>B3) and/or persistent (>2 years) pubertal gynecomastia (P/PPG) to determine whether a hormonal/genetic defect might underline this condition. Endocrine investigation revealed the absence of hormonal disturbance for 18 boys (72%). Three patients presented Klinefelter syndrome and three a partial androgen insensitivity syndrome (PAIS) as a result of p...
Source: Andrology - February 4, 2016 Category: Urology & Nephrology Authors: F. Paris, L. Gaspari, F. Mbou, P. Philibert, F. Audran, Y. Morel, A. Biason‐Lauber, C. Sultan Tags: Original Article Source Type: research

Male Breast: Clinical and Imaging Evaluations of Benign and Malignant Entities with Histologic Correlation
Breast cancer is an uncommon disease in men. As a result, the diagnosis may not initially be considered. Understanding the common benign and malignant entities affecting the male breast is critical for timely and accurate diagnosis in the primary care setting. Most patients present with a palpable breast mass or pain. The usual etiology is gynecomastia, the most common breast condition in males, but breast cancer must always be excluded through careful imaging evaluation when physical examination findings are suspicious or inconclusive. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - February 1, 2016 Category: Journals (General) Authors: Alec Chau, Neda Jafarian, Marilin Rosa Tags: Review Source Type: research

Gynecomastia and Hyperprolactinemia Secondary to Advanced Allergic Fungal Rhinosinusitis in a Pediatric Patient.
We present an immunocompetent pediatric patient who presented with gynecomastia and was found to have hyperprolactinemia. Imaging showed a sphenoid mass and referral was made for a pituitary tumor. The mass was not a pituitary tumor and he was formally diagnosed with allergic fungal sinusitis and treated surgically. There are no previous reports of allergic fungal rhinosinusitis causing pituitary dysfunction in a pediatric patient. We also present a brief review and discussion of the treatment of allergic fungal sinusitis. PMID: 26768883 [PubMed - in process] (Source: Turkish Neurosurgery)
Source: Turkish Neurosurgery - January 16, 2016 Category: Neurosurgery Authors: Menendez JY, Woodworth BA, Jr J Tags: Turk Neurosurg Source Type: research

Derivation of integration-free iPSCs from a Klinefelter syndrome patient.
CONCLUSIONS: KS patient-derived iPS cells that could differentiate into cardiomyocyte-like cells were established. PMID: 26709348 [PubMed - as supplied by publisher] (Source: Reproductive Biology)
Source: Reproductive Biology - January 16, 2016 Category: Reproduction Medicine Authors: Shimizu T, Shiohara M, Tai T, Nagao K, Nakajima K, Kobayashi H Tags: Reprod Med Biol Source Type: research

Postoperative Granulomas at Liposuction Incision Sites
Since most liposuction incisions heal uneventfully, difficult healing in such incisions must be investigated. In the cases of two gynecomastia liposuction patients in which a water-based lubricating gel was used on the liposuction incisions, the incisions failed to heal. For both patients, workup uncovered palisading granulomas at the lateral inframammary fold incision sites several months after otherwise successful surgeries. These two cases are presented and the previous literature is reviewed, with consideration given to the etiology and prevention of such granulomas. Level of Evidence: 5 Risk (Source: Aesthetic Surgery Journal)
Source: Aesthetic Surgery Journal - January 15, 2016 Category: Cosmetic Surgery Authors: Weniger, F. G., White, P. F., Barrero Castedo, C. E. Tags: Case Report Source Type: research

Volume: 22 Issue: 2
This study investigated the utility of online CME for emergency physicians in Nova Scotia. Early outcomes of arthroplasty of the first carpometacarpal joint using pyrocarbon spherical implantsGiven its workload, the first carpometacarpal joint is the most common hand joint to develop osteoarthritis. When nonsurgical, conservative treatment options fail, surgical management is warranted. Although several surgical procedures are available, hand surgeons are revisiting implant arthroplasty despite the absence of an ideal implant design and material. The physical and biological properties of pyrocarbon, however, have recently ...
Source: Plastic Surgery - January 12, 2016 Category: Cosmetic Surgery Source Type: research

Brazilian Portuguese version of the Short Mood and Feelings Questionnaire (SMFQ) for screening children and adolescents seeking plastic surgery
The development of patient-reported outcome (PRO) measures to assess emotional state in children and adolescents seeking plastic surgery is important to determine whether the intervention is indicated or not. According to the American Society of Plastic Surgeons, nearly 236,000 cosmetic plastic surgeries were performed in adolescents aged between 13 and 19 in 2012.1 In Brazil, there was an increase of 141% in the number of plastic surgeries performed in adolescents between 14 and 18 years. The most common cosmetic surgeries sought by girls both in Brazil and worldwide are liposuction and breast augmentation, and by boys, a...
Source: Journal of Plastic, Reconstructive and Aesthetic Surgery - January 7, 2016 Category: Cosmetic Surgery Authors: Eduardo Rodrigues Sucupira, Miguel Sabino Neto, Maria José Azevedo de Brito, Gal Moreira Dini, Lydia Masako Ferreira Source Type: research

[Tacrolimus-induced gynecomastia in a patient with polymyositis].
Authors: Muñoz Gómez MM, Montané E, Orellano AL, Olivé A PMID: 26678165 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - December 20, 2015 Category: Journals (General) Tags: Med Clin (Barc) Source Type: research

Cytological evaluation of breast lesions in symptomatic patients presenting to Kenyatta National Hospital, Kenya: a retrospective study
Conclusions: Breast cytology effectively diagnosed neoplastic and non-neoplastic breast lesions. Neoplastic breast lesions occurred more frequently in women whereas non-neoplastic lesions occurred more frequently in men. To address the limitations associated with narrative reporting of breast cytology results, a synoptic reporting format incorporating the United Kingdom’s National Health Service Breast Screening Programme’s diagnostic categories (C1 to C5) is recommended for adoption by this hospital. (Source: BMC Women's Health)
Source: BMC Women's Health - December 15, 2015 Category: OBGYN Authors: Ken NkongeEmily RogenaEdwin WalongDennis Nkonge Source Type: research

An Assessment of Gender Differences in Plastic Surgery Patient Education and Information in the United States: Are We Neglecting Our Male Patients?
Conclusions Many plastic surgeons choose to ignore or minimize male patients in their online marketing efforts. However, as the number of men seeking cosmetic procedures continues to grow, plastic surgeons will benefit from incorporating male patients into their practice model. (Source: Aesthetic Surgery Journal)
Source: Aesthetic Surgery Journal - December 15, 2015 Category: Cosmetic Surgery Authors: Sinno, S., Lam, G., Brownstone, N. D., Steinbrech, D. S. Tags: Original Article Source Type: research