Androgen treatment effects on hippocampus structure in boys with Klinefelter Syndrome
Klinefelter syndrome (KS) is a highly prevalent sex chromosome aneuploidy condition that affects up to 1 in 450 male births (Herlihy et al., 2011). The majority of affected males exhibit a 47,XXY karyotype, although more than one supernumerary X chromosome is sometimes observed (Rey et al., 2011, Boada et al., 2009). The physical phenotype typically includes tall stature, hypogonadism, reduced testosterone, infertility and gynecomastia. Features comprising the behavioral phenotype include mood symptoms and deficits in specific domains of cognitive function, predominantly language, learning and memory, and executive functio...
Source: Psychoneuroendocrinology - October 1, 2018 Category: Psychiatry Authors: Lara C. Foland-Ross, Judith Ross, Allan L. Reiss Source Type: research

Glandular Liposculpture in the Treatment of Gynecomastia
(Source: Aesthetic Plastic Surgery)
Source: Aesthetic Plastic Surgery - October 1, 2018 Category: Cosmetic Surgery Source Type: research

The Effect of Surgical Treatment for Gynecomastia on Quality of Life in Adolescents
Despite the psychosocial deficits associated with gynecomastia, surgical treatment of adolescent gynecomastia remains controversial. This longitudinal cohort study measures changes in health-related quality of life following surgical treatment of gynecomastia in adolescents. (Source: Journal of Adolescent Health)
Source: Journal of Adolescent Health - September 29, 2018 Category: Child Development Authors: Laura C. Nuzzi, Joseph M. Firriolo, Carolyn M. Pike, Felecia E. Cerrato, Amy D. DiVasta, Brian I. Labow Tags: Original article Source Type: research

Complications of Androgen Deprivation Therapy in Men With Prostate Cancer.
This article summarizes the key side effects associated with ADT and discusses strategies to optimize management. PMID: 30248169 [PubMed - in process] (Source: Oncology (Williston Park, N.Y.))
Source: Oncology (Williston Park, N.Y.) - September 18, 2018 Category: Cancer & Oncology Authors: Patil T, Bernard B Tags: Oncology (Williston Park) Source Type: research

Comparison of effects of aldosterone receptor antagonists spironolactone and eplerenone on cardiovascular outcomes and safety in patients with acute decompensated heart failure
AbstractDifferences in the clinical impacts of the aldosterone receptor antagonists spironolactone and eplerenone in patients with heart failure (HF) are unclear. Among 838 prospectively enrolled patients hospitalized for HF, 90 treated with eplerenone were compared with 90 treated with spironolactone. The primary endpoint was a composite of cardiovascular death and hospitalization. A serial evaluation of the clinical parameters was performed 1  year after discharge. The mean dose of spironolactone was 27 ± 8 mg and of eplerenone was 34 ± 15 mg. During follow-up (mea...
Source: Heart and Vessels - September 10, 2018 Category: Cardiology Source Type: research

Re: False Positive Uptake in Bilateral Gynecomastia on 68Ga-PSMA PET/CT Scan
No abstract available (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - September 8, 2018 Category: Nuclear Medicine Tags: Letter to the Editor Source Type: research

Changing practices: The addition of a novel surgical approach to gynecomastia
ConclusionThe “double donut” technique is particularly useful for males with grades II or III gynecomastia. It provides good wound results, with acceptable patient satisfaction and cosmetic outcomes. Although initially developed for patients with higher grade gynecomastia, the improved visibility and increased patient satisfaction allowed this to become the preferred technique at our institution. (Source: The American Journal of Surgery)
Source: The American Journal of Surgery - September 6, 2018 Category: Surgery Source Type: research

Atorvastatin induced gynecomastia in a dyslipidemic patient. A case report.
Authors: Bostanitis I, Tsalidou M PMID: 30145234 [PubMed - as supplied by publisher] (Source: Hellenic Journal of Cardiology)
Source: Hellenic Journal of Cardiology - August 27, 2018 Category: Cardiology Tags: Hellenic J Cardiol Source Type: research

Single-incision surgery for gynecomastia using TriPort: A case report.
Authors: Liu J, Han Y, Cheng K, Wang XH, Guo F, Yang ZL Abstract Gynecomastia is a common benign condition of the male breast, frequently observed in newborns, adolescents and the elderly. Surgical excision remains one of the most effective methods for the management of patients with gynecomastia, particularly those with fibrosis or a course of>1 year. The present study describes two cases of patients with gynecomastia and presents a novel method of treatment, combining endoscopic surgery and liposuction using a TriPort, which may effectively remove breast tissue and shorten hospitalization time compared with a ...
Source: Experimental and Therapeutic Medicine - August 19, 2018 Category: General Medicine Tags: Exp Ther Med Source Type: research

Clinical Characteristics of Asymmetric Bilateral Gynecomastia: Suggestion of Desirable Surgical Method Based on a Single-Institution Experience
(Source: Aesthetic Plastic Surgery)
Source: Aesthetic Plastic Surgery - August 9, 2018 Category: Cosmetic Surgery Source Type: research

Role of tamoxifen in idiopathic gynecomastia: A 10 ‐year prospective cohort study
The Breast Journal, EarlyView. (Source: The Breast Journal)
Source: The Breast Journal - August 6, 2018 Category: Cancer & Oncology Authors: Gurdeep S. Mannu MRCSEd , MariaSudul MSc , Joao H.Bettencourt ‐Silva PhD , Sandra MariaTsoti BSc , GilesCunnick FRCS , Sk FaridAhmed FRCS Source Type: research

Clinical and Etiological Aspects of Gynecomastia in Adult Males: A Multicenter Study.
Conclusions: Patients with gynecomastia presented more often with aesthetic concerns and secondarily with breast pain. The most frequent final diagnosis was idiopathic gynecomastia, whereas the most frequent identified etiologies were anabolic steroids consumption, hypogonadism, and use of pharmaceutical drugs. Despite the low frequency of etiologies such as thyroid dysfunction or adrenal carcinoma, we emphasize the importance of a thorough assessment of the patient, as gynecomastia may be the tip of the iceberg for the diagnosis of treatable diseases. PMID: 30003107 [PubMed - in process] (Source: Biomed Res)
Source: Biomed Res - July 15, 2018 Category: Research Authors: Costanzo PR, Pacenza NA, Aszpis SM, Suárez SM, Pragier UM, Usher JGS, Vásquez Cayoja M, Iturrieta S, Gottlieb SE, Rey RA, Knoblovits P Tags: Biomed Res Int Source Type: research

Prevalence, clinical characteristics and long-term outcomes of classical 11 β-hydroxylase deficiency (11BOHD) in Turkish population and novel mutations in CYP11B1 gene
ConclusionThis study presents the high allelic heterogeneity of CYP11B1 mutations in CAH patients from Turkey. Three dimensional protein simulations may provide additional support for the pathogenicity of the genetic alterations. Our results provide reliable information for genetic counseling, preventive and therapeutic strategies for the families.Graphical abstractA 3D structure of Cytochrome P450 11B1.Positions of all the coding region mutations in our cases are pointed by arrow, and marked by purple color for easy identification. (Source: The Journal of Steroid Biochemistry and Molecular Biology)
Source: The Journal of Steroid Biochemistry and Molecular Biology - July 11, 2018 Category: Biochemistry Source Type: research

The coexistence of Cushing syndrome and gynecomastia as the manifestations of adrenocortical carcinoma
Publication date: Available online 4 July 2018Source: The Kaohsiung Journal of Medical SciencesAuthor(s): Mongkontida Umphonsathien, Panudda Srichomkwun, Patinut Buranasupkajorn, Thiti Snabboon (Source: The Kaohsiung Journal of Medical Sciences)
Source: The Kaohsiung Journal of Medical Sciences - July 11, 2018 Category: Universities & Medical Training Source Type: research

When electrodiagnosis for tremor reveals a rare peripheral disease
ConclusionSpontaneous surface EMG activity compatible with fasciculations might be a valuable marker of a neuropathic tremor and potentially a revealing sign of SBMA. (Source: Neurophysiologie Clinique)
Source: Neurophysiologie Clinique - July 10, 2018 Category: Neuroscience Source Type: research

Évolution sous testostérone d’une dysphorie de genre dans un syndrome de Klinefelter
This report also highlights the fact that the percentage of patients with dysphoria, which is much higher among the Klinefelter syndromes in the literature, might be due to the lack of testosterone treatment. This atypical and uncommon observation could be sought at larger scales in patients with fluctuating dysphoria. Finally and more broadly, it also recalls the importance of researching the total testosterone levels of patients suffering from dysphoria, which do not suffer from a psychiatric pathology. (Source: Sexologies)
Source: Sexologies - July 10, 2018 Category: Sexual Medicine Source Type: research

Evolution under testosterone of a gender dysphoria in a Klinefelter syndrome
This report also highlights the fact that the percentage of patients with dysphoria, which is much higher among the Klinefelter syndromes in the literature, might be due to the lack of testosterone treatment. This atypical and uncommon observation could be sought at larger scales in patients with fluctuating dysphoria. Finally and more broadly, it also recalls the importance of researching the total testosterone levels of patients suffering from dysphoria, which do not suffer from a psychiatric pathology. (Source: Sexologies)
Source: Sexologies - July 10, 2018 Category: Sexual Medicine Source Type: research

Prevalence, clinical characteristics and long-term outcomes of classical 11 β-hydroxylase deficiency (11BOHD) in Turkish population and novel mutations in CYP11B1 gene
ConclusionThis study presents the high allelic heterogeneity of CYP11B1 mutations in CAH patients from Turkey. Three dimensional protein simulations may provide additional support for the pathogenicity of the genetic alterations. Our results provide reliable information for genetic counseling, preventive and therapeutic strategies for the families.Graphical abstractA 3D structure of Cytochrome P450 11B1.Positions of all the coding region mutations in our cases are pointed by arrow, and marked by purple color for easy identification. (Source: The Journal of Steroid Biochemistry and Molecular Biology)
Source: The Journal of Steroid Biochemistry and Molecular Biology - July 6, 2018 Category: Biochemistry Source Type: research

The coexistence of Cushing syndrome and gynecomastia as the manifestations of adrenocortical carcinoma
Publication date: Available online 4 July 2018Source: The Kaohsiung Journal of Medical SciencesAuthor(s): Mongkontida Umphonsathien, Panudda Srichomkwun, Patinut Buranasupkajorn, Thiti Snabboon (Source: The Kaohsiung Journal of Medical Sciences)
Source: The Kaohsiung Journal of Medical Sciences - July 6, 2018 Category: Universities & Medical Training Source Type: research

When electrodiagnosis for tremor reveals a rare peripheral disease
ConclusionSpontaneous surface EMG activity compatible with fasciculations might be a valuable marker of a neuropathic tremor and potentially a revealing sign of SBMA. (Source: Neurophysiologie Clinique)
Source: Neurophysiologie Clinique - July 5, 2018 Category: Neuroscience Source Type: research

Évolution sous testostérone d’une dysphorie de genre dans un syndrome de Klinefelter
This report also highlights the fact that the percentage of patients with dysphoria, which is much higher among the Klinefelter syndromes in the literature, might be due to the lack of testosterone treatment. This atypical and uncommon observation could be sought at larger scales in patients with fluctuating dysphoria. Finally and more broadly, it also recalls the importance of researching the total testosterone levels of patients suffering from dysphoria, which do not suffer from a psychiatric pathology. (Source: Sexologies)
Source: Sexologies - July 5, 2018 Category: Sexual Medicine Source Type: research

Evolution under testosterone of a gender dysphoria in a Klinefelter syndrome
This report also highlights the fact that the percentage of patients with dysphoria, which is much higher among the Klinefelter syndromes in the literature, might be due to the lack of testosterone treatment. This atypical and uncommon observation could be sought at larger scales in patients with fluctuating dysphoria. Finally and more broadly, it also recalls the importance of researching the total testosterone levels of patients suffering from dysphoria, which do not suffer from a psychiatric pathology. (Source: Sexologies)
Source: Sexologies - July 5, 2018 Category: Sexual Medicine Source Type: research

The coexistence of Cushing syndrome and gynecomastia as the manifestations of adrenocortical carcinoma
Publication date: Available online 4 July 2018 Source:The Kaohsiung Journal of Medical Sciences Author(s): Mongkontida Umphonsathien, Panudda Srichomkwun, Patinut Buranasupkajorn, Thiti Snabboon (Source: The Kaohsiung Journal of Medical Sciences)
Source: The Kaohsiung Journal of Medical Sciences - July 5, 2018 Category: Universities & Medical Training Source Type: research

Do Adolescents with Gynecomastia Require Routine Evaluation by Endocrinology?
Conclusions: Endocrinologic workup identified secondary gynecomastia in 7.6 percent of patients, of which only 1.7 percent were evident on blood work. This workup is associated with an avoidable case-cost burden to the health care system and largely unnecessary testing for the child. Because a majority of secondary gynecomastia cases (67 percent) were drug-induced, we do not suggest routine endocrinology workup, as it adds little value. The authors’ data suggest that referral for surgery is warranted if gynecomastia persists beyond 16 years of age. CLINICAL QUESTION/LEVEL OF EVIDENCE: Diagnostic, IV. (Source: Pl...
Source: Plastic and Reconstructive Surgery - June 29, 2018 Category: Cosmetic Surgery Tags: Cosmetic: Original Articles Source Type: research

Statin Medications and the Risk of Gynecomastia
Clinical Endocrinology,Volume 0, Issue ja, -Not available-. (Source: Clinical Endocrinology)
Source: Clinical Endocrinology - June 20, 2018 Category: Endocrinology Authors: Sean C Skeldon , Bruce Carleton , James Brophy , Mohit Sodhi , Mahyar Etminan Source Type: research

Gynecomastia after euthyroidism restoration in a patient with type 1 diabetes and Graves ’ disease
Clinical Case Reports, EarlyView. (Source: Clinical Case Reports)
Source: Clinical Case Reports - June 15, 2018 Category: General Medicine Authors: Valeria Calcaterra , Edoardo Clerici , Valeria Ceolin , Corrado Regalbuto , Daniela Larizza Source Type: research

Correction of Tuberous Nipple Areolar Complex Deformity in Gynecomastia: The Deformity That Can Get Forgotten
This article concentrates on the tuberous deformity of the nipple areolar complex (NAC) that can present in gynecomastia and is sometimes overlooked at surgical correction. This deformity can be corrected at primary surgery if it is recognized preoperatively. If missed, or not adequately corrected, the postoperative result of primary reduction may be deemed incomplete by the patient and they will request revision. The deformity involves overprojection of the NAC in an anteroposterior direction, yet the base diameter may be close to normal. Correction involves reduction of the herniated breast bud, excision of excess areo...
Source: Annals of Plastic Surgery - June 13, 2018 Category: Cosmetic Surgery Tags: Circumspectus Medicinae: Texts and Contexts Source Type: research

Evaluation of Glandular Liposculpture as a Single Treatment for Grades I and II Gynecomastia
(Source: Aesthetic Plastic Surgery)
Source: Aesthetic Plastic Surgery - June 4, 2018 Category: Cosmetic Surgery Source Type: research

X chromosome gain is related to increased androgen receptor expression in male breast cancer
AbstractX chromosome gain has been previously described in male breast cancer (MBC). Androgen receptor (AR) gene is located on X chromosome. The aim of this study was to investigate the role of the X chromosome gain in the development of MBC and its relation with AR gene copy number and expression.The X chromosome status was assessed in 66 cases of male invasive and in situ duct breast carcinoma, in 34 cases of gynecomastia associated with cancer, and in 11 cases of tumor-free gynecomastia. Cases were tested by fluorescence in situ hybridization (FISH) to assess the X chromosome status and AR amplification. AR expression w...
Source: Virchows Archiv - May 25, 2018 Category: Pathology Source Type: research

Potential case of gynecomastia in mummified remains of an early modern period northern finnish vicar
Clinical Anatomy, EarlyView. (Source: Clinical Anatomy)
Source: Clinical Anatomy - May 25, 2018 Category: Anatomy Authors: TiinaV äre , Francesco M.Galassi , JaakkoNiinimäki , Juho‐AnttiJunno Source Type: research

Potential case of gynecomastia in mummified remains of an early modern period northern finnish vicar
Clinical Anatomy,Volume 31, Issue 5, Page 641-644, July 2018. (Source: Clinical Anatomy)
Source: Clinical Anatomy - May 25, 2018 Category: Anatomy Authors: TiinaV äre , Francesco M.Galassi , JaakkoNiinimäki , Juho‐AnttiJunno Source Type: research

Is There a Rationale behind Pharmacotherapy in Idiopathic Gynecomastia?
Conclusion: High digit ratio in men with gynecomastia may tend to be a marker of overexpression of ER and PR. This may justify an early use of tamoxifen in men with gynecomastia and a high digit ratio.Horm Res Paediatr (Source: Hormone Research in Paediatrics)
Source: Hormone Research in Paediatrics - May 17, 2018 Category: Endocrinology Source Type: research

Diagnosis and Management of Gynecomastia for Urologists
AbstractPurpose of ReviewOur aim is to review the steps of diagnosis and management of gynecomastia with a special focus on treatment of gynecomastia associated with androgen deprivation therapy for prostate cancer.Recent FindingsRecent studies investigating tamoxifen and radiation therapy for both therapy and prophylaxis of bicalutamide-induced gynecomastia are reviewed.SummaryGynecomastia is a common clinical problem, affecting between one and two thirds of middle-aged men. Diagnosis is typically made by history and physical exam. Common causes include chronic medical conditions and medications; however, unexplained gyne...
Source: Current Urology Reports - May 17, 2018 Category: Urology & Nephrology Source Type: research

Recovery of reproductive function following androgen abuse
Purpose of review To summarize recent data on the adverse reproductive consequences of androgen abuse, focusing on the recovery of reproductive function following androgen discontinuation. Recent findings Evidence is mostly based on case reports and observational studies. Androgen abuse leads to a state of hypogonadotropic hypogonadism associated with impaired spermatogenesis, testicular atrophy, gynecomastia as well as menstrual irregularities, virilization and subfertility. Recovery of the hypothalamic–pituitary–gonadal axis following androgen withdrawal depends on the type and characteristics of androge...
Source: Current Opinion in Endocrinology, Diabetes and Obesity - May 2, 2018 Category: Endocrinology Tags: ANDROGENS: Edited by David Handelsman Source Type: research

New approach based on immunochemical techniques for monitoring of selective estrogen receptor modulators (SERMs) in human urine
Publication date: 15 July 2018 Source:Journal of Pharmaceutical and Biomedical Analysis, Volume 156 Author(s): J.-Pablo Salvador, Ester Vila-Roca, Núria Monfort, Rosa Ventura, M.-Pilar Marco Antiestrogenic compounds such as tamoxifen, toremifen and chlomifen are used illegally by athletes to minimize physical impacts such as gynecomastia resulting from the secondary effects of anabolic androgenic steroids, used to increase athletic efficiency unlawfully. The use of these compounds is banned by the World Anti-Doping Agency (WADA) and controls are made through analytical methodologies such as HPLC–MS/MS, which ...
Source: Journal of Pharmaceutical and Biomedical Analysis - April 26, 2018 Category: Drugs & Pharmacology Source Type: research

Prevalence, clinical characteristics and long-term outcomes of classical 11 β-hydroxylase deficiency (11BOHD) in Turkish population and novel mutations in CYP11B1 gene
Conclusion This study presents the high allelic heterogeneity of CYP11B1 mutations in CAH patients from Turkey. Three dimensional protein simulations may provide additional support for the pathogenicity of the genetic alterations. Our results provide reliable information for genetic counseling, preventive and therapeutic strategies for the families. Graphical abstract (Source: The Journal of Steroid Biochemistry and Molecular Biology)
Source: The Journal of Steroid Biochemistry and Molecular Biology - April 18, 2018 Category: Biochemistry Source Type: research

Glandular Liposculpture in the Treatment of Gynecomastia
(Source: Aesthetic Plastic Surgery)
Source: Aesthetic Plastic Surgery - April 11, 2018 Category: Cosmetic Surgery Source Type: research

"Post-finasteride syndrome": what to tell our female patients?
This article is protected by copyright. All rights reserved. PMID: 29624646 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 6, 2018 Category: Dermatology Authors: Mervis JS, Borda LJ, Miteva M Tags: Br J Dermatol Source Type: research

Estrogen-induced myelotoxicity in a 4-year-old golden retriever dog due to a Sertoli cell tumor.
Abstract A 4-year-old, unilateral cryptorchid golden retriever dog was presented to the Ontario Veterinary College Health Sciences Centre with gynecomastia, dribbling urine, lethargy, neutropenia, and thrombocytopenia. A Sertoli cell tumor was diagnosed in a cryptorchid testicle with estrogen-induced myelotoxicity. The tumor was removed and bone marrow regenerated within 4 months. PMID: 29606731 [PubMed - in process] (Source: The Canadian Veterinary Journal)
Source: The Canadian Veterinary Journal - April 1, 2018 Category: Veterinary Research Authors: Marshall H Tags: Can Vet J Source Type: research

A Young Male with Bilateral Gynecomastia [What Is Your Guess?]
(Source: Clinical Chemistry)
Source: Clinical Chemistry - March 28, 2018 Category: Chemistry Authors: Mohapatra, S., Chakraborty, S. Tags: What Is Your Guess? Source Type: research

Estrogen: The necessary evil for human health, and ways to tame it
Publication date: June 2018 Source:Biomedicine & Pharmacotherapy, Volume 102 Author(s): Seema Patel, Ahmad Homaei, Akondi Butchi Raju, Biswa Ranjan Meher Estrogen is a pivotal enzyme for survival and health in both genders, though their quantum, tropism, tissue-specific distribution, and receptor affinity varies with different phases of life. Converted from androgen via aromatase enzyme, this hormone is indispensable to glucose homeostasis, immune robustness, bone health, cardiovascular health, fertility, and neural functions. However, estrogen is at the center of almost all human pathologies as well-infectious, a...
Source: Biomedicine and Pharmacotherapy - March 22, 2018 Category: Drugs & Pharmacology Source Type: research

Estrogen: The necessary evil for human health, and ways to tame it.
Abstract Estrogen is a pivotal enzyme for survival and health in both genders, though their quantum, tropism, tissue-specific distribution, and receptor affinity varies with different phases of life. Converted from androgen via aromatase enzyme, this hormone is indispensable to glucose homeostasis, immune robustness, bone health, cardiovascular health, fertility, and neural functions. However, estrogen is at the center of almost all human pathologies as well-infectious, autoimmune, metabolic to degenerative. Both hypo and hyper level of estrogen has been linked to chronic and acute diseases. While normal aging is ...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - March 21, 2018 Category: Drugs & Pharmacology Authors: Patel S, Homaei A, Raju AB, Meher BR Tags: Biomed Pharmacother Source Type: research

Hypertrophic osteoarthropathy: estrogens, prostaglandinE 2 , prostaglandin A 2 , and the inflammatory reflex
AbstractIt has been claimed that hyperestrogenism occurs in hypertrophic osteoarthropathy (HOA), but not in simple clubbing. However, one of our patients had simple clubbing and hyperestrogenism. We therefore measured estrogens, androgens, sex hormone-binding globulin (SHBG), and gonadotropins in five patients with HOA and in 18 patients with simple clubbing. Of the patients with HOA, 80% had a high urinary estriol concentration. In their serum, 80% had high estrone, 0% high estradiol, and 40% high SHBG. Of the patients with simple clubbing, 89% had a high urinary estriol concentration. In their serum, 76% had high estrone...
Source: Clinical Rheumatology - February 26, 2018 Category: Rheumatology Source Type: research

The metabolic and endocrine characteristics in spinal and bulbar muscular atrophy
ConclusionsMetabolic alterations in glucose homeostasis (diabetes) and fat metabolism (combined hyperlipidemia), and sex hormone abnormalities (androgen insensitivity) could be observed among SBMA patients without association with the neuromuscular phenotype. Dehydroepiandrosterone sulfate was the only biomarker that correlated strongly with both weakness duration and the CAG repeat length after adjusting for age and BMI, indicating its potential as a biomarker for both disease severity and duration and, therefore, its possible use as a reliable outcome measure in future therapeutic studies. (Source: Journal of Neurology)
Source: Journal of Neurology - February 20, 2018 Category: Neurology Source Type: research

Clinical Characteristics of Asymmetric Bilateral Gynecomastia: Suggestion of Desirable Surgical Method Based on a Single-Institution Experience
AbstractBackgroundAsymmetric bilateral gynecomastia (ABGM) is uncommon, and reports on its characteristics are rare. In the present study, we investigated the clinical characteristics and surgical treatment of ABGM.MethodsWe conducted a retrospective study of 1159 patients with gynecomastia who underwent subcutaneous mastectomy with liposuction at Damsoyu Hospital from January 2014 to February 2016. We then analyzed differences in the characteristics and operative results between two groups of patients: those with asymmetric and symmetric gynecomastia. Asymmetric gynecomastia was defined as gynecomastia meeting both of the...
Source: Aesthetic Plastic Surgery - February 20, 2018 Category: Cosmetic Surgery Source Type: research

Évolution sous testostérone d’une dysphorie de genre dans un syndrome de Klinefelter
This report also highlights the fact that the percentage of patients with dysphoria, which is much higher among the Klinefelter syndromes in the literature, might be due to the lack of testosterone treatment. This atypical and uncommon observation could be sought at larger scales in patients with fluctuating dysphoria. Finally and more broadly, it also recalls the importance of researching the total testosterone levels of patients suffering from dysphoria, which do not suffer from a psychiatric pathology. (Source: Sexologies)
Source: Sexologies - February 16, 2018 Category: Sexual Medicine Source Type: research

Evolution under testosterone of a gender dysphoria in a Klinefelter syndrome
This report also highlights the fact that the percentage of patients with dysphoria, which is much higher among the Klinefelter syndromes in the literature, might be due to the lack of testosterone treatment. This atypical and uncommon observation could be sought at larger scales in patients with fluctuating dysphoria. Finally and more broadly, it also recalls the importance of researching the total testosterone levels of patients suffering from dysphoria, which do not suffer from a psychiatric pathology. (Source: Sexologies)
Source: Sexologies - February 7, 2018 Category: Sexual Medicine Source Type: research

Does Prophylactic Radiotherapy to avoid Gynecomastia in Patients with Prostate Cancer increase the risk of Breast Cancer?
In this study with data from the Norwegian Cancer Registry, we did not find increased risk of breast cancer (BC) in irradiated patients compared to non-irradiated patients. It is noteworthy that in the RT group, there were two cases of malignant phyllodes breast tumor, an extremely rare type of BC associated with gynecomastia. (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - February 5, 2018 Category: Radiology Authors: Bj ørg Y. Aksnessæther, Arne Solberg, Olbjørn H. Klepp, Tor Åge Myklebust, Eva Skovlund, Solveig Roth Hoff, Lars J. Vatten, Jo-Åsmund Lund Tags: Clinical Investigation Source Type: research

Does Prophylactic Radiation Therapy to Avoid Gynecomastia in Patients With Prostate Cancer Increase the Risk of Breast Cancer?
Prostate cancer (PC) patients who undergo antiandrogen monotherapy are offered prophylactic radiation therapy (PRT) to the breast buds to avoid gynecomastia. The aim of the present study was to evaluate whether the risk of breast cancer (BC) in men with PC as their first cancer diagnosis was influenced by PRT. (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - February 5, 2018 Category: Radiology Authors: Bj ørg Y. Aksnessæther, Arne Solberg, Olbjørn H. Klepp, Tor Åge Myklebust, Eva Skovlund, Solveig Roth Hoff, Lars J. Vatten, Jo-Åsmund Lund Tags: Clinical Investigation Source Type: research