The electroneutral Na < sup > + < /sup > -HCO < sub > 3 < /sub > < sup > - < /sup > cotransporter NBCn1 (SLC4A7) modulates colonic enterocyte pH < sub > i < /sub > , proliferation and migration
Am J Physiol Cell Physiol. 2024 Apr 22. doi: 10.1152/ajpcell.00079.2024. Online ahead of print.ABSTRACTNBCn1 (SLC4A7) is one of the two major Na+-HCO3- cotransporters in the human colonic epithelium, expressed predominantly in the highly proliferating colonocytes at the cryptal base. Increased NBCn1 expression levels are reported in tumours, including colorectal cancer. The study explores its importance for maintenance of the intracellular pH (pHi),as well as the proliferative, adhesive, and migratory behavior of the self-differentiating Caco2bbe colonic tumour cell line. In the self-differentiating Caco2BBe cells, NBCn1 m...
Source: Am J Physiol Cell Ph... - April 22, 2024 Category: Cytology Authors: Min Jiang Azam Salari Christian Stock Katerina Nikolovska Ebbe Boedtkjer Mahdi Amiri Ursula E Seidler Source Type: research
The electroneutral Na < sup > + < /sup > -HCO < sub > 3 < /sub > < sup > - < /sup > cotransporter NBCn1 (SLC4A7) modulates colonic enterocyte pH < sub > i < /sub > , proliferation and migration
Am J Physiol Cell Physiol. 2024 Apr 22. doi: 10.1152/ajpcell.00079.2024. Online ahead of print.ABSTRACTNBCn1 (SLC4A7) is one of the two major Na+-HCO3- cotransporters in the human colonic epithelium, expressed predominantly in the highly proliferating colonocytes at the cryptal base. Increased NBCn1 expression levels are reported in tumours, including colorectal cancer. The study explores its importance for maintenance of the intracellular pH (pHi),as well as the proliferative, adhesive, and migratory behavior of the self-differentiating Caco2bbe colonic tumour cell line. In the self-differentiating Caco2BBe cells, NBCn1 m...
Source: American Journal of Physiology. Cell Physiology - April 22, 2024 Category: Cytology Authors: Min Jiang Azam Salari Christian Stock Katerina Nikolovska Ebbe Boedtkjer Mahdi Amiri Ursula E Seidler Source Type: research
The electroneutral Na < sup > + < /sup > -HCO < sub > 3 < /sub > < sup > - < /sup > cotransporter NBCn1 (SLC4A7) modulates colonic enterocyte pH < sub > i < /sub > , proliferation and migration
Am J Physiol Cell Physiol. 2024 Apr 22. doi: 10.1152/ajpcell.00079.2024. Online ahead of print.ABSTRACTNBCn1 (SLC4A7) is one of the two major Na+-HCO3- cotransporters in the human colonic epithelium, expressed predominantly in the highly proliferating colonocytes at the cryptal base. Increased NBCn1 expression levels are reported in tumours, including colorectal cancer. The study explores its importance for maintenance of the intracellular pH (pHi),as well as the proliferative, adhesive, and migratory behavior of the self-differentiating Caco2bbe colonic tumour cell line. In the self-differentiating Caco2BBe cells, NBCn1 m...
Source: Am J Physiol Cell Ph... - April 22, 2024 Category: Cytology Authors: Min Jiang Azam Salari Christian Stock Katerina Nikolovska Ebbe Boedtkjer Mahdi Amiri Ursula E Seidler Source Type: research
The electroneutral Na < sup > + < /sup > -HCO < sub > 3 < /sub > < sup > - < /sup > cotransporter NBCn1 (SLC4A7) modulates colonic enterocyte pH < sub > i < /sub > , proliferation and migration
Am J Physiol Cell Physiol. 2024 Apr 22. doi: 10.1152/ajpcell.00079.2024. Online ahead of print.ABSTRACTNBCn1 (SLC4A7) is one of the two major Na+-HCO3- cotransporters in the human colonic epithelium, expressed predominantly in the highly proliferating colonocytes at the cryptal base. Increased NBCn1 expression levels are reported in tumours, including colorectal cancer. The study explores its importance for maintenance of the intracellular pH (pHi),as well as the proliferative, adhesive, and migratory behavior of the self-differentiating Caco2bbe colonic tumour cell line. In the self-differentiating Caco2BBe cells, NBCn1 m...
Source: American Journal of Physiology. Cell Physiology - April 22, 2024 Category: Cytology Authors: Min Jiang Azam Salari Christian Stock Katerina Nikolovska Ebbe Boedtkjer Mahdi Amiri Ursula E Seidler Source Type: research
The electroneutral Na < sup > + < /sup > -HCO < sub > 3 < /sub > < sup > - < /sup > cotransporter NBCn1 (SLC4A7) modulates colonic enterocyte pH < sub > i < /sub > , proliferation and migration
Am J Physiol Cell Physiol. 2024 Apr 22. doi: 10.1152/ajpcell.00079.2024. Online ahead of print.ABSTRACTNBCn1 (SLC4A7) is one of the two major Na+-HCO3- cotransporters in the human colonic epithelium, expressed predominantly in the highly proliferating colonocytes at the cryptal base. Increased NBCn1 expression levels are reported in tumours, including colorectal cancer. The study explores its importance for maintenance of the intracellular pH (pHi),as well as the proliferative, adhesive, and migratory behavior of the self-differentiating Caco2bbe colonic tumour cell line. In the self-differentiating Caco2BBe cells, NBCn1 m...
Source: Am J Physiol Cell Ph... - April 22, 2024 Category: Cytology Authors: Min Jiang Azam Salari Christian Stock Katerina Nikolovska Ebbe Boedtkjer Mahdi Amiri Ursula E Seidler Source Type: research
